The alkaloid pattern of the endemic plant Papaver coreanum Nakai (Papaveraceae) was determined for the first time. Eight alkaloids could be identified by LC/ESIMS/MS and high-resolution mass spectrometry. Among them, protopine and allocryptopine represent the main components. Besides norsanguinarine, sanguinarine, dihydrosanguinarine, oxysanguinarine, lincangenine, and cryptopine, some other trace alkaloids were found whose structures remain unknown.
Herbs in Changbaek Mountain (1982) Jilin Province, Institute of Chinese Medicine and Medicinal Plant (Ed.), Jilin, China, 468–470.
2.
BokLT. (1980) Illustrated Flora of Korea.Hyangmun Publication, Seoul, Korea, 380.
3.
FrickS, KramellR, SchmidtJ, FistAJ, KutchanTM. (2005) Comparative qualitative and quantitative determination of alkaloids in narcotic and condiment Papaver somniferum cultivars. Journal of Natural Products, 68, 666–673.
4.
SchmidtJ, BoettcherC, KuhntC, KutchanTM, ZenkMH. (2007) Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding. Phytochemistry, 68, 189–202.
5.
LiscombeDK, ZieglerJ, SchmidtJ, AmmerC, FacchiniPJ. (2009) Targeted metabolite and transcript profiling for elucidating enzyme function: Isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species. Plant Journal, 60, 729–743.
HegnauerR. (1990) Chemotaxonomie der Pflanzen.BirkhäuserVerlag Basel, Vol. IX, 187–208.
8.
PreiningerV. (1986) Chemotaxonomy of Papaveraceae and Fumariaceae. The Alkaloids: Chemistry and Pharmacology. Vol. 29, BrossiA. (Ed.), Academic Press, Orlando USA, 1–98.
9.
KutchanTM. (1998) Molecular Genetics of Plant Alkaloid Biosynthesis. The Alkaloids: Chemistry and Biology. Vol. 50, CordellGA. (Ed.), Academic Press, California USA, 257–316.
10.
ShulginAT, PerryWE. (2002) The simple plant isoquinolines.Transform Press, Berkeley, California USA.
11.
ChenY, Sheng-DingF, LiHW, LiYH, YangHM. (1991) Studies on the alkaloids of Stephania lincangensis (Chinese). Zhiwuxue Bao, 33, 552–555.
12.
Barbosa-FilhoJM, da-CunhaEVL, GrayAI. (2000) Alkaloids of the Menispermaceae. The Alkaloids: Chemistry and Biology. Vol. 54, 1–190.
13.
DostalJ, SlavikJ. (2000) Novčjší poznatky o sanguinarinu a příbuzných alkaloidech (recent knowledge on sanguinarine and related alkaloids). Chemicke Listy, 94, 15–20.
