Two new biflavonoids, 4′-methoxydaphnodorin D1 and 4′-methoxydaphnodorin D2, along with six known biflavonoids, were isolated from the roots of Wikstroemia indica. The structures of the new compounds were determined by extensive NMR and HRESIMS spectroscopic analyses in combination with CD measurements.
A group of editors for Chinese Materia Medica. (1999) Chinese Materia Medica. In Wikstroemia indica (Linn) C. A. Mey. Shanghai Science and Technology Press, Shanghai, China, 423–427.
2.
LeeK.H., TagaharaK., SuzukiH., WuR.Y., HarunaM., HallI.H., HuangH.C., ItoK., IidaT., LaiJ.S. (1981) Antitumor Agents. 49. Tricin, kaempferol-3-O-beta-D-glucopyranoside and (+)-nortrachelogenin, antileukemic principles from Wikstroemia indica. Journal of Natural Products, 44, 530–535.
3.
HuK., KobayashiH., DongA., IwasakiS., YaoX. (2000) Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Medica, 66, 564–567.
4.
NunomeS., IshiyamaA., KobayashiM., OtoguroK., KiyoharaH., YamadaH., OmuraS. (2004) In vitro antimalarial activity of biflavonoids from Wikstroemia indica. Planta Medica, 70, 76–78.
5.
WangL.Y., UneharaT., KitanakaS. (2005) Anti-inflammatory activity of new guaiane type sesquiterpene from Wikstroemia indica. Chemical and Pharmaceutical Bulletin, 53, 137–139.
6.
HuangW.H., LiY.L., WangH., SuM.X., JiangZ.Y., OoiV.E.C., ChungH.Y. (2009) Toxicological study of a Chinese herbal medicine, Wikstroemia indica. Natural Product communications, 4, 1227–1230.
7.
HoW.S., XueJ.Y., SunS.S.M., OoiV.E.C., LiY.L. (2010) Antiviral activity of daphnoretin isolated from Wikstroemia indica. Phytotherapy Research, 24, 657–661.
8.
HuangW.H., ZhangX.L., WangY.F., YeW.C., OoiV.E.C., ChungH.Y., LiY.L. (2010) Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen). Chinese Medicine, 5, no pp. given.
9.
BabaK., TakeuchiK., KozawaM. (1987) Chemical studies on the constituents of the Thymelaeaceous plants. V. Structure of a new biflavonoid, daphnodorin D from the root of Daphne odora Thunb. Yakygaku Zasshi, 107, 863–868.
10.
TaniguchiM., FujiwaraA., BabaK. (1997) Three flavonoids from Daphne odora. Phytochemistry, 45, 183–188.
11.
BabaK., TaniguchiM., KozawaM. (1994) Three biflavonoids from Wikstroemia sikokiana. Phytochemistry, 37, 879–883.
12.
NiwaM., TatematsuH., LiuG.Q., HirataY. (1984) Isolation and structures of two new C-3/C-3″-biflavanones, neochamaejasmin A and neochamaejasmin B. Chemistry Letters, 13, 539–542.
13.
TaniguchiM., FujiwaraA., BabaK., WangN.H. (1998) Two biflavonoids from Daphne acutiloba. Phytochemistry, 49, 863–867.
