From the commercial extract of the leaves of Stevia rebaudiana, two additional new diterpenoid glycosides were isolated and their structures were characterized as 13-[(2-O-β-D-glucopyranosyl-3-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester (1) and 13-[(2-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy] ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester (2) on the basis of extensive spectral data (NMR and MS) and chemical studies.
BrandleJ.E., StarrrattA.N., GijenM. (1998) Stevia rebaudiana: its agricultural, biological and chemical properties. Canadian Journal of Plant Sciences, 78, 527–536.
2.
ChaturvedulaV.S.P., RheaJ., MilanowskiD., MocekU., PrakashI. (2011) Two minor diterpenoid glycosides from the leaves of Stevia rebaudiana. Natural Product Communications, 6, 175–178.
3.
ChaturvedulaV.S.P., ClosJ.F., RheaJ., MilanowskiD., MocekU., DuBoisG.E., PrakashI. (2011) Minor diterpenoid glycosides from the leaves of Stevia rebaudiana. Phytochemistry Letters, in press
4.
KohdaH., KasaiR., YamsakiK., MurakamiK., TanakaO. (1976) New sweet diterpene glucosides from Stevia rebaudiana. Phytochemistry, 15, 981–983.
5.
KobayashiM., HorikawaS., DegrandiI.H., UenoJ., MitsuhashiH. (1977) Dulcosides A and B, new diterpene glycosides from Stevia rebaudiana. Phytochemistry, 16, 1405–1408.
6.
StarrattA.N., KirbyC.W., PocsR., BrandleJ.E. (2002) Rebaudioside F, a diterpene glycoside from Stevia rebaudiana. Phytochemistry, 59, 367–370.
7.
SakamotoI., YamasakiK., TanakaO. (1977) Application of 13C NMR spectroscopy to chemistry of plant glycosides: rebaudiosides D and E, new sweet diterpene glucosides of Stevia rebaudiana Bertoni. Chemical and Pharmaceutical Bulletin, 25, 3437–3439.
8.
OhtaniK., AikawaY., KasaiR., ChouW., YamasakiK., TanakaO. (1992) Minor diterpene glycosides from sweet leaves of Rubus suavissimus. Phytochemistry, 31, 1553–1559.
9.
BedirE., ToyangN.J., KhanI.A., WalkerL.A., ClarkA.M. (2001) A new dammarane type triterpene glycoside from Polyscias fulva. Journal of Natural Products, 64, 95–97.
10.
ChaturvedulaV.S.P., SchillingJ.K., MillerJ.S., AndriantsiferanaR., RasamisonV.E., KingstonD.G.I. (2003) New cytotoxic oleanane saponins from the infructescences of Polyscias amplifolia from the Madagascar rainforest. Planta Medica, 69, 440–444.
TanakaT., NakashimaT., UedaT., TomiiK., KounoI. (2007) Facile discrimination of aldose enantiomers by reversed-phase HPLC. Chemical and Pharmaceutical Bulletin, 55, 899–901.