Two new steroidal alkaloids (1-2) have been isolated from the leaves and roots of Solanum hypomalacophyllum Bitter, respectively. Their structures have been elucidated as deacetoxysolaphyllidine-3-O-β-D-glucopyranoside (1) and 4-keto-5,6-dihydro-(20S)-verazine (2). Furthermore, two known steroidal alkaloids, 20R-verazine and 20S-verazine, and the common secondary metabolites oleanolic acid and β-sitosterol were isolated from the roots, whereas deacetoxysolaphyllidine was obtained from the leaves.
ColettoA, KinuppV, AbsyM, KerrW. (2004) Pollen morphology and study of the visitors (Hymenoptera, Apidae) in central Amazoniam. Acta Botánica Brasilica, 18653-657.
2.
ChowdhuryN, BhattacharjeeI, LaskarS, ChnadraG. (2007) Efficacy of Solanum villosum Mill. (Solanaceae: Solanales) as a biocontrol agent against fourth instar larvae of Culex quinquefasciatus Say. Turkish Journal of Zoology, 31365-370.
3.
RoddickJ, WeissenbergM, LeonardA. (2001) Membrane disruption and enzyme inhibition by naturally-occurring and modified chacotriose-containing Solanum steroidal glycoalkaloids. Phytochemistry, 56603-610.
4.
SinghO, SubharaniK, SinghN, DeviN, NeviditaL. (2007) Isolation of steroidal glycosides from Solanum xanthocarpum and studies on their antifungal activities. Natural Product Research, 21585-590.
5.
ArthanD, SvatiJ, KittakoopP, PittayakhachonwutD, TanticharoenM, ThebtaranonthY. (2002) Antiviral isoflavonoid sulfate and steroidal glycosides from the fruits of Solanum torvum. Phytochemistry, 59459-463.
6.
WanyonviA, ChhabraS, MkojiG, NjueW, TarusP. (2003) Molluscicidal and antimicrobial activity of Solanum aculeastrum. Fitoterapia, 74298-301.
7.
KeelerR, BakerD, GaffieldW. (1990) Spirosolane-containing Solanum species and induction of congenital craniofacial malformations. Toxicon, 28873-884.
8.
LuY, LuoJ, HuangX, KongL. (2009) Four new steroidal glycosides from Solanum torvum and their cytotoxic activities. Steroids, 7495-101.
9.
UsubillagaA. (1984) Alkaloids from Solanum hypomalacophyllum. Journal of Natural Products, 4752-54.
10.
UsubillagaA, SeelkopfC, KarleI, DalyJ, WitkopB. (1970)Structure of solaphyllidine, a novel 4-oxosteroidal alkaloid. Journal of the American Chemical Society, 92700-701.
11.
KarleI. (1970) The crystal structure of solaphyllidine, C29H47NO5, a new steroidal alkaloid. Acta Crystallographica, B26, 1639-1645.
12.
AlarcónL, VelascoJ, UsubillagaA. (2006) Determinación de la actividad antibacteriana de los alcaloides presentes en los frutos verdes del Solanum hypomalacophyllum Bitter. Revista Latinoamericana de Química, 3415-21.
13.
HanX, RüeggerH. (1992) Epimeric (20R, 20S)-verazine isolated from Veratrum maackii: two-dimensional NMR studies and total assignment of 1H- and 13C-resonances. Planta Medica, 58449-453.
14.
De ValeriB, UsubillagaA. (1989) Sapogenins from Solanum meridense. Phytochemistry, 282509-2511.