Two novel antioxidants, obtusilactone A (1) and (-)-sesamin (2) have been identified in Cinnamomum kotoense Kanehira. Both showed effective 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity compared with vitamin C, and reducing power compared with BHA. These results suggest that these constituents of C. kotoense act as natural antioxidants and play a potential role in cancer prevention.
JinD, HakamataH, TakahashiK, KotaniA, KusuF. (2004) Determination of quercetin in human plasma after ingestion of commercial canned green tea by semi-micro HPLC with electrochemical detection. Biomedical Chromatography, 18, 662–666.;
WangDF, LiJ, WangCH, ZhaoGW, JinY, ChenDD, YeS. (2000) Study on the component and immune activity of polysaccharides from tea. Journal of Tea Science, 1, 45–50;
4.
ScalbertA, JohnsonIT, SaltmarshM. (2005) Polyphenols: antioxidants and beyond. American Journal of Clinical Nutrition, 81, S215–S217;
5.
LuY, FooLY. (1997) Identification and quantification of major polyphenols in apple pomace. Food Chemistry, 59, 187–194;
6.
SurhYJ. (2003) Cancer chemoprevention with dietary phytochemicals. Nature Reviews Cancer, 3, 768–780.
7.
LiaoJC. (1996) Lauraceae in Flora of Taiwan, 2nd ed. Editorial Committee of the Flora of Taiwan: Taipei, 2, 443–483;
8.
ChenCH, LoWL, LiuYC, ChenCY. (2006) Chemical and cytotoxic constituents from the leaves of Cinnamomum kotoense. Journal of Natural Products, 69, 927–933;
9.
ChenCY. (2006) Butanolides from the stems of Cinnamomum kotoense. Natural Product Communications, 1, 453–455;
10.
ChenFC, PengCF, TsaiIL, ChenIS. (2005) Antitubercular constituents from the stem wood of Cinnamomum kotoense. Journal of Natural Products, 68, 1318–1323.
11.
BaschalEE, ChenKJ, ElliottLG, HerringMJ, VerdeSC, WolkowTD. (2006) The fission yeast DNA structure checkpoint protein Rad26ATRIP/LCD1/UVSD accumulates in the cytoplasm following microtubule destabilization. BMC Cell Biology, 7, 32;
12.
MaricS, JukicM, KatalinicV, MilosM. (2007) Comparison of chemical composition and free radical scavenging ability of glycosidically bound and free volatiles from Bosnian pine (Pinus heldreichii Christ. var. leucodermis). Molecules, 12, 283–289;
13.
GülçinI, ElmastasM, Aboul-EneinHY. (2001) Determination of antioxidant and radical scavenging activity of basil (Ocimum basilicum L.family Lamiaceae). Phytotherapy Research, 21, 354–361.