The hydrodistilled volatile oil from the aerial parts of Artemisia kulbadica Boiss. & Buhse was investigated by a combination of GC and GC/MS. Twenty-seven compounds were identified, representing 92.9% of the total oil. Sabinene (25.1%), trans-thujone (18.7%) and γ-cadinene (16.0%) were the main components. The antimicrobial activity was determined against six bacterial strains and one fungal. The oil was active against all the tested strains.
RechingerKH. (1980) Artemisia. In Flora Iranica. Compositae, RechingerKH, HedgeIC (Eds), No. 158, P.185–216, Akademische Druck and Verlagsanstalt, Graz, Austria, 214.
2.
MozaffarianV. (1996) ArtemisiaL. (Compositae) In A dictionary of Iranian Plant Names. Farhang Mo'aser Publishers, Tehran, Iran.
3.
LiGQ, GuoXB, JinR, WangZC, JianHX, LiZY. (1982) Clinical studies on treatment of cerebral malaria with ginghaosu and its derivatives. Journal of Traditional Chinese Medicine, 2, 125–130.
4.
KlaymanDL, LinAJ, ActonN, ScovillJP, HochuJM, MilkhousWK, TheoharidesAD, DobekAS. (1984). Isolation of artemisinin (Qinghaosu) from Artemisia annua growing In the United States. Journal of Natural Products, 47, 715–716.
5.
BiliaAR, KaiserM, VincieriFF, TasdemirD. (2008) Antitrypanosomol and antileishmaial activities of organic and aqueous extracts of Artemisia annua. Natural Product Communications, 3, 1963–1966.
6.
VincieriFF, BillaAR. (2008) Comparative analysis of antimalarial principles in Artemisia annua L. herbal drugs from East Africa. Natural Product Communications, 3, 2003–2006.
7.
BiliaAR, De MalgalhaesPM, BergonziMC, VincieriFF. (2006) Simultaneous analysis of artemisinin and flavonoids of several extracts of Artemisia annua L. obtained from a commercial sample and a selected cultivar. Phytomedicine, 13, 487–493.
8.
BiliaAR, FlaminiG, MorgenniF, IsacchiB, VincieriFF. (2008) GC MS analysis of the volatile constituents of essential oil and aromatic water of Artemisia annua L. at different developmental stages. Natural Product Communications, 3, 2075–2078.
9.
JuteauF, MasottiV, BessiereJM, DherbomezM, VianoJ. (2002) Antibacterial and antioxidant activities of Artemisia annua essential oil. Fitoterapia, 73, 532–535.
10.
JuteauF, JerkovicL, MasottiV, MilosM, MastelicJ, BessiereJM, VianoJ. (2003) Composition and antimicrobial activity of the essential oil of Artemisia absinthium from Croatia and France. Planta Medica, 69, 158–161.
11.
RustaiyanA, SigariH, JakupovicJ, GrenzM. (1989) A sesquiterpene lactone from Artemisia diffusa. Phytochemistry, 28, 2723–2725.
12.
RustaiyanA, NahrevanianH, KazemiM. (2007) Effects of extracts of Artemisia diffusa against Plasmodium berghei as a new antimalarial agent. BIT's 5thAnniversary Congress of International Drug Discovery Science and Technology (IDDBST), May 28-June 5, Shanghai, China.
13.
Khazraei-AlizadehK, RustaiyanA, MasoudiS. (2002) Composition of the volatile oil of Artemisia diffusa Krasch. ex Poljak. growing wild in Iran. Journal of Essential Oil Research, 13, 185–186.
14.
RamazaniM, Fazli-BazzazBS, Saghafi-KhademF, DabaghianA. (2004) Antimicrobial activity of four Artemisia species of Iran. Fitoterapia, 75, 201–203.
GuoevenalpZ, CakirA, HarmandarM, GleispachH. (1998) The essential oils of Artemisia austriaca and Artemisia spicigera C. Koch, from Turkey. Flavour and Fragrance Journal, 13, 26–28.
17.
SunY, LiYH, WuXX, ZhengW, GuoZH, LiY, ChenT, HuaZC, XuQ. (2006) Ethanol extract from Artemisia vestita, a traditional Tibetan medicine, exerts anti-sepsis action through down-regulating the MAPK and NF-κB pathways. International Journal of Molecular Medicine, 17, 957–962.
18.
SayyahM, NadjafiniaL, KamalinejadM. (2004) Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil. Journal of Ethnopharmacology, 94, 283–287.
19.
BohlmanF, BurkhardtT, ZedroC. (1972) Naturally Occurring Acetylenes, Academic Press, New York, NY.
WollenweberE, Favre-BonvinH, HoulvilleM, RustaiyanA. (1992) A phloracetophenone derivative and flavonoid aglycones from the lipophilic exudates of Artemisia aucheri. Phytochemistry (Life Science Advances), 11, 105–107.
22.
RybalkoKS, KonovalovaOA, SheichenkoVI, ZakharovPI. (1977) Armin-A new coumarin from Artemisia armeniaca. Chemistry of Natural Compounds, 12, 262–265.
23.
RustalyanA, ZareK, GanjiMT, SadriHA. (1986) A melampolide and two dihydro artemorin derivatives from Artemisia gypsacea. Phytochemistry, 28, 1535–1536.
24.
RustaiyanA, BamoniriA, RaffatradM, JakupovicJ, BohlmannF. (1987) Eudesmane derivatives and highly oxygenated monoterpenes from Iranian Artemisia species. Phytochemistry, 26, 2307–2310.
FirouzniaA, TaghiAkbari M, RustaiyanA, MasoudiS, BigdeliM, Tabtabaei-AnarakiM. (2007) Composition of the essential oils of Artemisia turanica Krasch., Helichrysum oocephalum Boiss. and Centaurea ispahanica Boiss. three Asteraceae herbs growing wild in Iran. Journal of Essential Oil Bearing Plants, 10, 88–93.
27.
RustaiyanA, MasoudiS, KazemiM. (2007) Volatile oils constituents from different parts of Artemisia ciniformis Krasch. et M. Pop. ex Poljak and Artemisia incana (L.) Druce. from Iran. Journal of Essential Oil Research, 19, 548–551.
28.
NematollahiF, RustaiyanA, LarijaniK, NadimiM, MasoudiS. (2006) Essential oil composition of Artemisia biennis Wild. and Pulicaria undulata (L.) C.A. Mey., two Compositae herbs growing wild in Iran. Journal of Essential Oil Research, 18, 339–341.
29.
MirjaliliBF, Hakimi-MeybodyMH, Mazloum-ArdakaniM, RustaiyanA, AmeriN, MasoudiS, BamoniriA. (2006) Chemical composition of the essential oil from aerial parts, leaves, flowers and roots of Artemisia persica Boiss. from Iran. Journal of Essential Oil Research, 18, 544–547.
30.
Khorsand-MohammadpoorS, YariM, RustaiyanA, MasoudiS. (2002) Chemical constituents of the essential oil of Artemisia aucheri Boiss. a species endemic to Iran. Journal of Essential Oil Research, 14, 122–123.
31.
ChagondaLS, MakandaC, ChalchatJC. (1999) The essential oil of cultivated Artemisia afra Jacq. from Zimbabwe. Flavour and Fragrance Journal, 14, 140–142.
32.
ShahGC, MathelaCS. (2006) Essential oil constituent of Artemisia wallichiana Bess. Journal of Essential Oil Research, 18, 377–378.
33.
BarazandehMM.. (2003) Essential oil composition of Artemisia fragrans Willd. from Iran. Journal of Essential Oil Research, 15, 414–415
34.
BicchiC, RubioloP.MarschallH, WeyerstahlP, LaurentR. (1998) Constituents of Artemisia roxburghiana Besser essential oil. Flavour and Fragrance Journal, 13, 40–45.
35.
HaiderF, DwivediPD, NaqviAA, BagchiGD. (2003) Essential oil composition of Artemisia vulgaris harvested at different growth periods under Indo-Gangetic plain conditions. Journal of Essential Oil Research, 15, 376–378.
36.
ArzeJBL, CollinG, GarneauFX, JeanFI, GagnonH. (2004) Essential oils from Bolivia. III. Asteraceae: Artemisia copa Philippi. Journal of Essential Oil Research, 16, 554–557.
37.
RustaiyanA, BalalaeiS, MohammadiF, MasoudiS, YariM. (2000) Comparison of the volatile oils of Artemisia santolina Schrenk and Artemisia gypsacea Krasch., M. Pop. et Lincz. ex Poljak. from Iran. Journal of Essential Oil Research, 12, 330–332.
38.
GravenEH, DeanSG, SvobodaKP, MaviS, GundidzaMG. (2006) Antimicrobial and antioxidative properties of the volatile (essential) oil of Artemisia afra Jacq. Flavour and Fragrance Journal, 7, 121–123.
39.
HaiderF, NaqviAA, BagchiGD. (2006) Chemical constituents of Artemisia verlotiorum essential oil on cultivation at the subtropical conditions of North India. Journal of Essential Oil Research, 18, 551–552.
40.
QiuHX, LeiY, HuangJ. (2006) Seasonal analyses of the essential oil of Artemisia ferganensis. Journal of Essential Oil Research, 18, 357–359.
41.
WeyerstahlP, MarschallH, KaulVK. (2006) The essential oil of Artemisia moorcroftiana Wall. Flavour and Fragrance Journal, 7, 73–77.
42.
ShafiPM, NambiarMKG, CleryRA, SarmaYR, VeenaS. (2004) Composition and antifungal activity of the oil of Artemisia nilagirica (Clarke) Pamp. Journal of Essential Oil Research, 16, 377–379.
43.
AkroutA, ChemliR, SimmondsM, KiteG, HammamiM, ChreifI. (2003) Seasonal variation of the essential oil of Artemisia campestris L. 15, 333–336.
44.
SilvestreAJD, SilvaAMS, AlmeidaLMPM, PereiraCCL, CavaleiroJAS. (1999) The essential oil of Artemisia campestris L. subsp. maritima Arcangelis. Acta Horticulturae, 500, 93–96.
45.
MassadaY. (1976) Analysis of Essential Oil by Gas Chromatography and spectrometry. Wiley: New York.
46.
AdamsRP. (2000) Identification of Essential Oil Components by Gas Chromatography/Quadruple Mass spectroscopy, Allured Publishing Corp., Carol Stream, IL.
47.
RamaswamiSK, BrisceseP, GargiulloRJ, VonngeldernT. (1988) A World Perspective, LawrenceBM, MookerjeeBD, WillisBJ (Eds). Elsevier, Amsterdam, p. 951.
48.
Van Den DoolH, KratzPD. (1963) A generalization of the retention index system including linear temperature programmed gasliquid partition chromatography. Journal of Chromatography, 11, 463–471.
49.
BaronEJ, FinegoldSM. (1995) Bailey and Scott's Diagnostic Microbiology, 8th ed. Mosby, St. Louis, MO, USA.
50.
PattnaikS, SubramanyamVR, BapajiM, KoleCR. (1997) Antibacterial and antifungal activity of aromatic constituents of essential oils. Microbios, 89, 39–46.
51.
TzakouO, PitarokiliD, ChinouIB, HarvalaC. (2001) Composition and antimicrobial activity of the essential oil of Salvia ringens. Planta Medica, 67, 81–83.
52.
DormanHJD, DeansSG. (2000) Antimicrobial agents from plants: antibacterial activity of plant volatile oils. Journal of Applied Microbiology, 88, 308–316.
53.
Vardar-UnluG, CandanF, SokmenA, DafereraD, PolissiouM, SokmenM, DonmezE, TepeB. (2003) Antimicrobial and antioxidant activity of the essential oil and methanol extracts of Thymus pectinatus Fisch. et Mey. var. pectinatus (Lamiaceae),. Journal of Agricultural and Food Chemistry, 51, 63–67.