Three new and four known iridoids have been isolated from the leaves of Spathodea campanulata, the structures of the new compounds were determined as 6-O-trans-caffeoyl-decinnamoyl globularimin, 6-O-trans-caffeoyl-asystasioside E and 6-O-trans-caffeoyl-5,7-bisdeoxycynanchoside and provisionally named as spatheosides A (1), B (2) and C (3) respectively. The known iridoids were identified as verminoside (4), 6′-O-trans-caffeoyl-loganic acid (5), catalpol (6) and ajugol (7). The structures of the isolated compounds were characterized by different spectroscopic methods.
ScoginR. (1980) Anthocyanins of the Bignoniaceae. Biochemical Systematics and Ecology, 8, 273–276
5.
NgouelaS, TsamoE, SondengamBL. (1988) Extractives from Bignoniaceae: Constituents of the stem bark of Spathodea campanulata. Planta Medica, 54, 476
6.
NgouelaS, NyasseB, TsamoE, SondengamBL, ConnollyJD. (1990) Sapthodic acid: A triterpene acid from the stem bark of Spathodea campanulata. Phytochemistry, 29, 3959–3961
7.
NgouelaS, TsamoE, SondengamBL, ConnollyJD. (1991) Spathodol, a new polyhydroxysterol from the leaves of Spathodea campanulata. Journal of Natural Products, 54, 873–876
8.
SaxenaS, PantN, JainDC, BhakuniRS. (2003) Antimalarial agents from plant sources. Current Science, 85, 1314–1329
9.
MbossoEJT, NgouelaS, NguediaJCA, PenlapV, RohmerM, TsamoE. (2008) Spathoside, a cerebroside and other antibacterial constituents of the stem bark of Spathodea campanulata. Natural Product Research, 22, 296–304.
10.
El-HelaAA. (2001) Phenolics from Spathodea campanulata P. Beauvois leaves. Al-Azhar Journal of Pharmaceutical Sciences, 27, 152–161
SubramanianSS, SulochanaN, NagarajanS. (1973) Caffeic acid from the leaves of Spathodea campanulata. Current Science, 42, 403
13.
El-HelaAA. (2001) A new iridoid glucoside from Spathodea campanulata P. Beauvois leaves. Al-Azhar Journal of Pharmaceutical Sciences, 27, 115–119
14.
von PoserGL, SchripsemaJ, HenriquesAT, JensenSR. (2000) The distribution of iridoids in Bignoniaceae. Biochemical Systematics and Ecology, 28, 351–366.
15.
TrigoJR, Dos SantosWF. (2000) Insect mortality in Spathodea campanulata P. Beauvois Bignoniaceae flowers. Revista Brasileira de Biologia, 60, 537–538
16.
NiyonzimaG, LaekemanG, WitrrouwM, Van PoelB, PieterL, PaperD, De dercqG, FranzG, VlietinckA. (1999) Hypoglycemic, anticomplement and anti-HIV activities of Spathodea campanulata stem bark. Phytomedicine, 6, 45–49
17.
MakindeJM, AmusanOO, AdesoganEK. (1988) The antimalarial activity of Spathodea campanulata stem bark extract on Plasmodium berghei berghei in mice. Planta Medica, 54, 122–125
18.
AmusanOOG, MsonthiJD, MakhubuLP. (1995) Molluscicidal activity of Spathodea campanulata, Andrachne ovalis, Phytolacca dodecandra and Hypoxis rooperi. Fitoterapia, 66, 113–116
19.
AmusanOOG, AdesoganEK, MakindeJM. (1996) Antimalarial active principles of Spathodea campanulata stem bark. Phytotherapy Research, 10, 692–693.
SticherO, Afifi-YazarFÜ. (1979) Minecoside und Verminoside, zwei neue Iridoidglucoside aus Veronica officinalis L. (Scrophulariaceae). Helvetica Chemica Acta, 62, 535–539.
29.
El-NaggarLJ, BealJL. (1980) Iridoids. A review. Journal of Natural Products, 43, 649–707.