Aqueous preparations and ethanolic extracts of three Brazilian chemotypes of Lippia alba (Mill.) N.E. Brown (Verbenaceae) were investigated for the chemical variability of their non volatile constituents by HPLC/DAD/ESI-MS analysis. The main class of compounds in all the extracts investigated was phenylpropanoids, mainly verbascoside, followed by the flavonoids tricin-7-O-diglucuronide (present in Lippia alba chemotypes 2 and 3), luteolin-7-O-glucuronide (present in L. alba chemotype 1) and mono-and di-O-glucuronic derivatives of apigenin and tricin. Four iridoids, geniposidic acid, theveside, 8-epi-loganin and mussaenoside were also identified.
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