Two new cycloartane glycosides were isolated from the whole herbs of Camptosorus sibiricus Rupr.. By means of chemical and spectroscopic methods (IR, 1D- and 2D- NMR, HRMS, ESI-MS), the structures were established as (24R)-3β,7β,24,25,30-pentahydroxycycloartane 3-O-β-D-glucopyranosyl-24-O-β-D-glucopyranosyl-30-O-β-D-glucopyranoside (1), and (24R)-3β,7β,24,25,30-pentahydroxycycloartane 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl-24-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside (2). The two new compounds were tested for their cytotoxicity in vitro against human tumor cell lines (A375-S2, Hela) using the MTT method, but both compounds were inactive.
ZhangBF, WangSJ. (1979) Studies on Comptosorus sibiricus Rupr. used for cardiovascular diseases. Journal of Shenyang Pharmaceutical University, 11, 29–35.
2.
LiN, LiX, MaZJ, WangJH. (2005) A new cycloartane glycoside from the whole herbs of Comptosorus sibiricus Rupr.. Journal of Asian Natural Product Research, 7, 161–164.
3.
LiN, LiX, ZhangP, LiZL, YangSL, WangJH. (2004) New cycloartane glycoside from Camptosorus sibiricus Rupr.. Archives of Pharmacal Research, 27, 727–729.
4.
LiN, LiX, YangSL, WangJH. (2006) A new cycloartane glycoside from Camptosorus sibiricus Rupr.. Natural Product Research, 20, 1041–1045.
5.
HuaHM, LiX, PeiYH. (2001) A review on spectroscopic characteristics of cycloartane triterpenoids. Natural Product Research Development, 13, 65–70.
6.
IsaevMI, GorovitsMB, AbubakirovNK. (1989) Triterpene glycosides of Astragalus and their genins XXX. Cycloaraloside A from Astragalus amarus. Chemistry of Natural Compounds (English Translation), 684–687.
7.
IsaevMI, ImomnazarovBA, FadaevYM, KintyaPA. (1992) Triterpene glycosides of Astragalus and their genins XLII. Cycloartanes of Astragalus tragacantha. Chemistry of Natural Compounds (English Translation), 315–320.
8.
CalisI, ZorM. (1996) Four novel cycloartane glycosides from Astragalus oleifolius. Journal of Natural Products, 59, 1019–1023.
