5α, 8α-Epidioxy-24(S)-ethylcholest-6-en-3β-ol (1) was isolated from the marine sponge Biemna triraphis Topsent collected at Andavadoaka, near Toliary (west coast of Madagascar-Indian Ocean). The structure was elucidated from NMR spectroscopic data. This is the first report of this compound in a marine sponge belonging to the Biemna genus.
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