Three new flavonoids, namely 6-methoxyluteolin-4′-O-lactate, apigenin-4′-O-α-L-rhamnopyranoside and tamarixetin-3-{O-[β-D-glucopyranosyl-(1→2)]-α-L-rhamnopyranoside}-7-O-β-D-glucopyranoside, together with six known flavones have been isolated from the aerial parts of Ambrosia maritima L. The structures of the isolated compounds have been established by conventional methods of chemical and physical analyses and were confirmed by 1H and 13C NMR spectroscopy.
MironeC, AlbertF, TosiA, MocchettiF, MoscaS, GiorginoM, PecoraS, ParmianS, OrtolaniC. (2004) Efficacy and safety of subcutaneous immunotherapy with a biologically standardized extract of Ambrosia artemisiifolia pollen: a double-blind, placebo-controlled study. Clinical and Experimental Allergy, 34, 1408–1414.
2.
BoulosL. (1983) Medicinal Plants of North Africa.Reference Publications Inc., Michigan, USA.
3.
BoulosL. (1966) Flora of the Nile Region in Egyptian Nubia. Feddes Repertorium, 73, 184–215.
4.
BarclayAS, PerdueRE. (1976) Distribution of anticancer activity in higher plants. Cancer Treatment Reports.60, 1081–1113.
5.
AliAA, ShawanMM, KilaniAI, KamelNA, HareediMA. (2001) Study of the hypoglycaemic activity of Ambrosia maritima. International Congress and 49th Annual Meeting of the Society for Medicinal Plant Research, Erlangen, Germany.
6.
HeylFW. (1919) The yellow coloring substances of ragweed pollen. Journal of the American Chemical Society, 41, 1285–1289.
7.
WollenweberE, HradetzkyD, MannK, RoitmanJN, YatskievychG, ProkschM, ProkschP. (1987) Exudate flavonoids from aerial parts of five Ambrosia species. Journal of Plant Physiology, 131, 37–43.
8.
HerzW, SumiY. (1964) Constituents of Ambrosia hispida Pursh. Journal of Organic Chemistry, 29, 3438–3439.
9.
HerzW, AndersonGD, WagnerH, MaurerG, FloresG, FarkasL. (1973) Isolierung, synthese und strukturbeweis von 5, 7–dihydroxy-3, 4′, 6, 8-tetramethoxy-flavon, einem neuen flavon aus Ambrosia grayi Nelson. Tetrahedron Letters, 2571–2572.
10.
SeamanF, RodriguezE, CarmanNJ, MabryTJ. (1972) A new flavonoid from Ambrosia dumosa.Phytochemistry, 11, 2626–2627.
11.
FukuiK, NakayamaM, HorieT. (1970) Synthetic studies of the flavone derivatives. XVII. Synthesis of 5,7-dihydroxy-6-methoxyflavone derivatives. Bulletin of the Chemical Society of Japan, 43, 1524–1529.
12.
WollenweberE, Valant-VetscheraKM, IvanchevaS, KuzmanovB. (1987) Flavonoid aglycones from the leaf surfaces of some Achillea species. Phytochemistry, 26, 181–182.
13.
HarborneJB, ChristineAW. (1971) 6-Hydroxyluteolin and scutellarein as phyletic markers in higher plants. Phytochemistry, 10, 367–378.
14.
MarkhamKR. (1982) Techniques of Flavonoids Identification.Academic Press, London.
15.
AgrawalPK. (1989) Carbon-13 NMR of Flavonoids.Elsevier, New York.
