A new rearranged abietane diterpenoid, eriophoroxide (1), was obtained from the root extract of Salvia eriophora Boiss. and Kotschy ex Boiss. Its structure was elucidated by spectroscopic methods and semi-empirical/ab-initio calculations. DNA damaging, cytotoxic and antioxidant activities of the plant extract were tested.
MortonJF (1981) Atlas of Medicinal Plants of Middle America, ThomasCC (Ed.). Springfield, Illinois, 780–784.
5.
HedgeIC (1982) Salvia. In Flora of Turkey and the East Aegean Islands, Vol 7, DavisPH (Ed.), University Press, Edinburgh, 400–459.
6.
UlubelenA, TopçuG, ChaiHB, PezzutoJM (1999) Cytotoxic activity of diterpenoids isolated from Salvia hypargeia.Pharmaceutical Biology, 37, 148–151.
7.
UlubelenA, TopçuG (1998) Chemical and biological investigations of Salvia species growing in Turkey. In Studies in Natural Products Chemistry. Vol 20, Atta-ur-Rahman (Ed). Elsevier Science, Amsterdam, 659–718.
8.
TopçuG, TürkmenZ, UlubelenA, SchillingJ, KingstonDGI (2004) Highly hydroxylated triterpenes from Salvia kronenburgii.Journal of Natural Products, 67, 118–121.
9.
TopçuG, AltınerEN, GözcüS, HalfonB, AydoğmuşZ, PezzutoJM, ZhouBN, KingstonDGI (2003) Cytotoxic di- and triterpenoids from Salvia staminea.Planta Medica, 69, 464–467.
10.
UlubelenA, ÖksüzS, TopçuG, GörenAC, Bozok-JohanssonC, ÇelikC, KökdilG, VoelterW (2001) A new antibacterial diterpene from the roots of Salvia caespitosa.Natural Product Letters, 15, 307–314.
11.
UlubelenA, TopçuG, Bozok-JohanssonC (1997) Norditerpenoids and diterpenoids from Salvia multicaulis with antituberculous activity. Journal of Natural Products, 60, 1275–1280.
12.
UlubelenA, ÖksüzS, KolakU, TanN, Bozok-JohanssonC, ÇelikC, KohlbauHJ, VoelterW (1999) Diterpenoids from the roots of Salvia bracteata.Phytochemistry, 52, 1455–1459.
13.
GörenAC, TopçuG, ÖksüzS, KökdilG, VoelterW, UlubelenA (2002) Diterpenoids from Salvia ceratophylla.Natural Product Letters, 16, 47–52.
14.
TopçuG, UlubelenA (1990) Diterpenoids from Salvia wiedemannii.Phytochemistry, 29, 2346–2348.
15.
UlubelenA, TopçuG, TanN (1995) Diterpenoids from Salvia heldreichiana.Phytochemistry, 40, 1473–1475.
16.
UlubelenA, TopçuG, ErişC, SönmezU, KartalM, KurucuS, Bozok-JohanssonC (1994) Terpenoids from Salvia sclarea.Phytochemistry, 36, 971–974.
17.
ChangHM, ChengKP, ChoangTF, ChowHF, ChuiKY, HonPM, TanFWL, YangY, ZhongZP, LeeCM, ShamHL, ChanCF, CuiYX, WongHNC (1990) Structure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge. Journal of Organic Chemistry, 55, 3537–3543.
18.
UlubelenA, BirmanH, ÖksüzS, TopçuG, KolakU, BarlaA, VoelterW (2002) Cardioactive diterpenes from the roots of Salvia eriophora.Planta Medica, 68, 818–821.
19.
DewarMJS, ZoebischEG, HealyEF, StewartJJP (1985) AM1: A general purpose quantum mechanical molecular model. Journal of the American Chemical Society, 107, 3902–3909.
20.
BeckeAD (1997) Density-functional thermochemistry. V. Systematic optimization of exchange-correlation functionals. Journal of Chemical Physics, 107, 8554–8560.
21.
SchmiderHL, BeckeAD (1998) Optimized density functionals from the extended G2 test set. Journal of Chemical Physics, 108, 9624–9631.
22.
LevineIN (2000) Quantum Chemistry. Prentice Hall Inc., New York, 693–709.