Chemical analysis of the stem bark of Cylicodiscus gabunensis (Mimosaceae) yielded, in addition to the known eryhrodiol (4) and sojagol (IV) (5), three new glycosides designated coumestoside A (1), coumestoside B (2) and erythrodiside A (3). Their structures were established by chemical and spectroscopic means as 9-O-β-D-glucopyranosyl-4-hydroxycoumestrol, 9-O-α-L-rhamnopyranosyl-4-hydroxycoumestrol and 3-O-α-L-rhamnopyranosylerythrodiol-28-O-β-D-galactopyranoside, respectively.
KouitcheuMLB, PenlapBV, KouamJ, OyonoE, EtoaFX. (2007) Toxicological evaluation of ethyl acetate extract of Cylicodiscus gabunensis bark (Mimosaceae), Journal of Ethnopharmacology, in press, (available online at www.sciencedirect.com)
2.
KouitcheuMLB, PenlapBV, KouamJ, NgadjuiBT, FomumZT, EtoaFX. (2006) Evaluation of antidiarrhoealactivity of the stem bark of Cylicodiscus gabunensis (Mimosaceae). African Journal of Biotechnology, 5, 1062–1066.
3.
KouitcheuMLB, PenlapBV, KouamJ, NgadjuiBT, FomumZT, EtoaFX. (2007) Evaluation of antimicrobial activity of the stem bark of Cylicodiscus gabunensis (Mimosaceae). African Journal of Traditional, Complementary and Alternative Medicines, 4, 87–93.
4.
JudeEO, BasilNI, AniekanEU. (2006) Antiplasmodial activity of Cylicodiscus gabunensis.Journal of Ethnopharmacology, 107, 175–178
5.
RichterHG, DallwitzMJ. 2000 onwards. Commercial timbers descriptions, illustrations, identification, and information retrieval. In English, French, German, Portuguese, and Spanish. Version: 16th April 2006, http://delta-intkey.com.
6.
TaneP, BergquisK-E, TénéM, NgadjuiTB, AyaforJF, OlovS. (1995) Cyliclodione, an unsymetrical dimeric diterpene from Cylicodiscus gabunensis.Tetrahedron, 51, 11595–11600.
TchivoundaHP, KoudogboB, BesaceY, CasadevallE. (1990) Cylicodiscic acid, a dihydroxypentacyclic triterpene carboxylic acid from Cylicodiscus gabunensis.Phytochemistry, 29, 3255–3258.
9.
GuJH, JungJH, KimK – J, KimM –S, HongJ. (2006) Structural determination of saponins extracted from starfish by fast atom bombardment collision-induced dissociation mass spectrometry. Analytical Science, 22, 641–644.
10.
YadavaRN. (2001) A new biologically active triterpenoid saponin from the leaves of Lepidagathis hyalina Nees. Natural Product Letters, 15, 315–322.
11.
NaimaB, BéchirH, GeorgesL, MohamedA. (2001) Contribution à l’étude de l'activité biologique d'extaits de feuilles de Cestrum parqui L'Hérit. (Solanaceae) sur le criquet pèlerin Schistocerc gregaria (Forsk). Biotechnology, Agronomy, Society and Environment, 5, 85–90.
12.
ZiloH, GrisebachH. (1968) Biosynthesis of isoflavone – XVII. Identification and biosynthesis of coumestanesin Soja Hispida, Phytochemistry, 7, 1765–1772.
13.
NkenfackAE, KouamJ, VouffoTW, MeyerM, TempestaMS, FomumZT. (1994) An isoflavanone and a coumetan from Erythrina sigmoidea.Phytochemistry, 15, 521–526
FranciscoAV, RaimundoB-F, YvoneBMP, ManoelAN, GilvandeteMPS, EdsonR-F. (2004) Triterpenoid saponins from stem bark of Pentaclethra macroloba.Journal of the Brazilian Chemical Society, 15, 595–602.
16.
WilliamKA, AbdallahAO, BroggerC. (1987) Isorhamnetin 3–(2,6-dirhamnosylgalactoside)–7-rhamnoside and 3–(6– rhamnosylgalatoside–7-rhamnoside from Rhazya stricta.Phytochemistry, 26, 291–294.
17.
ToriK, SeoS, ShimaokaA, TomitaY. (1974) Carbon-13 NMR spectra of olean-12-ene. Full signal assignments including quaternary carbon signals. Assigned by use of indirect 13C, 1H spin coupling. Tetrahedron Letters, 4227–4230.
18.
ToriK, SeoS, YoshimuraY, AritaH, TomitaY. (1977) Glycosidation shifts in carbon-13 NMR spectroscopy: Carbon-13 signal shifts from aglycone and glucose to glucoside. Tetrahedron Letters, 179–182.
19.
KouamJ, NkengfackAE, FomumZT, UbillasR, TempestaMS. (1991) Two new triterpenoid saponins from Erythrina sigmoidea.Journal of Natural Products, 54, 1288–1292.
20.
NkenfackAE, KouamJ, VouffoWT, FomumZT, DagneE, SternerO, BrownLM, JiG. (1993) Further flavonoids from Erythrina species. Phytochemistry, 32, 1305–1311.