Although there are a number of Ruta species in the world, R. graveolens L., R. chalepensis L., R. montana (L.) L., R. angustifolia Pers. and R. pinnata L. fil. are the most studied. However, the first two of them have been the most extensively investigated for their chemical constituents and biological activities. They are used for their anthelmintic, diuretic, emmenagogue, and aphrodisiac properties. In dermatology, they are used against psoriasis and vitiligo, and as mycosis fungicides. In many countries, the plant extracts have been used as birth control agents.
SteckW, BaileyBK, ShylukJP, GamborkOL. (1971) Coumarins and alkaloids from cell cultures of Ruta graveolens. Phytochemistry, 10, 191–194.
2.
ReischJ, NovakI, SzendreiK, MinkerE. (1967) Rutamarin ein cumarin-derivat aus Ruta graveolens. Acta Pharmaceutica Suecica, 4, 179–181.
3.
ReischJ, SzendreiK, NovakI, MinkerE, RózsaZs. (1971) Acridone alkaloids of callus tissue of Ruta graveolens. Experientia, 27, 1005–1007.
4.
ReischJ, SzendreiK, RózsaZs, NovakI, MinkerE. (1972) Rutacultin und rutamarin alcohole aus den wurzeln von Ruta graveolens. Phytochemistry, 11, 1529–1530.
5.
BrookerRM, EbleJN, StarkowskyNA. (1967) Chalepensin, chalepin and chalepin acetate, three novel furocoumarins from Ruta chalepensis. Lloydia, 30, 73–77.
6.
NovakI, BuzasG, MinkerE, KoltaiM, SzendreiK. (1965) Ein neues alkaloid aus Ruta graveolens L. Pharmazie, 20, 655–658.
7.
ReischJ, RózsaZs, SzendreiK, MinkerE. (1972) Weitere acridone-alkaloide aus Ruta graveolens. Phytochemistry, 11, 2121–2122.
ReischJ, RózsaZs, SzendreiK, KöresiJ. (1975) 2-(N-Undecyl-chinolon-(4) aus den blüten von Ptelea trifoliata und wurzeln von Ruta graveolens. Phytochemistry, 14, 840–841.
ReischJ, RoszaZs, SzendreiK, NovakI, MinkerE. (1977) Furoacridone, 1-hydroxy-3-methoxy-N-methyl-acridon und isogravacridonchlorin aus den wurzeln von Ruta graveolens. Phytochemistry, 16, 151–152.
12.
GrundonMF, OkelyHM. (1979) A new quinoline alkaloid from Ruta graveolens. Phytochemistry, 18, 1768–1769.
13.
UlubelenA, TeremB, TuzlacıE, ChengKF, KongYC. (1986) Alkaloids and coumarins from Ruta chalepensis. Phytochemistry, 25, 2692–2693.
14.
UlubelenA, TeremB. (1988) Alkaloids and coumarins from the roots of Ruta chalepensis. Phytochemistry, 27, 650–651.
15.
UlubelenA, GünerH, ÇetindağM. (1988) Alkaloids and coumarins from the roots of Ruta chalepensis var. latifolia. Planta medica, 54, 551–552.
16.
UlubelenA, GünerH. (1988) Isolation of dehydromoskachan C from Ruta chalepensis var. latifolia. Journal of Natural Products, 51, 1012–1013.
17.
UlubelenA, TanN. (1990) A moskachan from roots of Ruta chalepensis. Phytochemistry, 29, 3991–3992.
18.
UlubelenA, ErtugrulL, BirmanH, YiğitR, ErsevenG, OlgaçV. (1994) Antifertility effects of some coumarins isolated from Ruta chalepensis and Ruta chalepensis var. latifolia in rodents. Phytotherapy Research, 8, 233–236.
19.
UlubelenA. (1990) A new alkaloid montanine from Ruta montana. Journal of Natural Products, 53, 207–208.
20.
UlubelenA, DoğancaS. (1991) Constituents of the aerial parts of Ruta montana. Fitoterapia, 62, 279.
ChiuKW, FungAYL. (1997) The cardiovascular effect of green beans (Phaseolus aureus), common rue (Ruta graveolens) and kelp (Laminaria japonica) in rats. General Pharmacology, 29, 859–862.
23.
Aguilar-SantamariaL, TortorielloJ. (1998) Anticonvulsant and sedative effects of crude extracts of Ternstroemia priglei and Ruta chalepensis. Phytotherapy Research, 10, 531–533.
24.
AttaAH, AlkofahiA. (1998) Anti-nociceptive and anti-inflammatory effects of some Jordanian medicinal plant extracts. Journal of Ethnopharmacology, 60, 117–124.
25.
HmamouchiM, LahlouM, AgoumiA. (2000) Moluscicidal activity of some Moroccan medicinal plants. Fitoterapia, 71, 308–314.
26.
OlivaA, LahozE, ContilloR, AliottaG. (1999) Fungistatic activity of Ruta graveolens extract and its allelochemicals. Journal of Chemical Ecology, 25, 519–525.
27.
KostovaI, IvanovaA, MikhovaB, KlaiberI. (1999) Alkaloids and coumarins from Ruta graveolens. Monatshefte für Chemie, 130, 703–707.
28.
Zeichende-Sa R, ReyA, ArganarazE, BindsteinE. (2000) Perinatal toxicology of Ruta chalepensis (Rutaceae) in mice. Journal of Ethnopharmacology, 69, 93–98.
29.
ChenC-C, HuangY-L, WangC-W, OuJ-C. (2001) Water soluble glycosides from Ruta graveolens. Journal of Natural Products, 64, 990–992.
30.
MilesiS, MassotB, GontierE, BourgautF, GuckertA. (2001) Ruta graveolens L.: A promising species for the production of furanucoumarins. Plant Science, 161, 189–199.
De FrietasTG, AugustoPM, MontanariT. (2005) Effect of Ruta graveolens on pregnant mice. Contraception, 71, 74–77.
33.
RaghavSK, GuptaB, AgrawalC, GoswamiK, DasHR. (2006) Anti-inflammatory effect of Ruta graveolens L. in murine macrophage cells. Journal of Ethnopharmacology, 104, 234–239.
34.
IaukL, ManganoK, RapisardaA, RagusaS, MaiolinoL, MusumeciR, CostanzoR, SerraA, SpecialeA. (2004) Protection against murine endotoxemia by treatment with Ruta chalepensis L. a plant with anti-inflammatory properties. Journal of Ethnopharmacology, 90, 267–272.
35.
MeepagalaKM, SchraderKK, WedgeDE, DukeSO. (2005) Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs. Phytochemistry, 66, 2689–2695.
36.
PauliniH, WaibelR, KieferJ, SchimmerO. (1991) Gravacridonediol acetate, a new dihydrofuroacridone alkaloid from Ruta graveolens. Planta Medica, 57, 82–83.
