The composition of the volatile leaf oil of Ficus exasperata Vahl (Moraceae) is reported. The oil was obtained by hydrodistillation and analyzed for its constituents by means of gas chromatography-mass spectrometry (GC-MS). The oil is comprised of terpenoids and aliphatic compounds. The quantitatively significant compounds were 1,8-cineole (13.8%), (E)-phytol (13.7%) and p-cymene (11.4%). In addition, all other compounds were present above 2%. The oil shows no antibacterial activity against the tested organisms (MIC 625ppm).
MousaaO, VuorelaP, KivirantaJ, WahabSA, HiltumenR. (1999) Bioactivity of certain Egyptian Ficus species. Journal of Ethnopharmacology, 41, 71–76.
2.
OkaforJI, EzeEA, NjokuOU. (2001) Antifungal activities of the leaves of Baphia nitida, Cassia alata, Ficus exasperata and Gossypium arboretum. Nigerian Journal of Natural Product and Medicine, 5, 59–60.
3.
Nimenibo-UadiaR. (2003) Ficus exasperata: effects on diabetes mellitus in an experimental rat model. Global Journal of Pure and Applied Sciences, 9, 529–532.
4.
AkahPA, OrisakweOE, GamanielKS, ShittuA. (1998) Evaluation of Nigerian traditional medicines: II. Effects of some Nigerian folk remedies on peptic ulcer. Journal of Ethnopharmacology, 62, 123–127.
5.
OgunleyeDS, AdeyemiAO, SanniSA. (2003) Hypoglycaemic activities of the stem bark of Cola acuminata Vahl and leaf of Ficus exasperata (P. Beauv) Schott & Endl. Nigerian Quarterly Journal of Hospital Medicine, 13, 58–60.
6.
MacfoyCA, ClineEI. (1990) In vitro antibacterial activities of three plants used in traditional medicine in Sierra Leone. Journal of Ethnopharmacology, 28, 323–327.
7.
UmerieSC, OgbuaguAS, OgbuaguJO. (2004) Stabilization of palm oils by using Ficus exasperata leaves in local processing methods. Bioresource Technology, 94, 307–310.
8.
AdebayoAS, GbadamosiIA, AdewunmiCO, AdesinaSK. (2001) Influence of herbal materials on soap foaming and organolepsis. Nigerian Journal of Natural Products and Medicine, 5, 41–44.
9.
BaahJ, TaitRM, TuahAK. (1999) The effect of supplementation with Ficus leaves on the utilization of cassava peels by sheep. Bioresource Technology, 67, 47–51
10.
AporiSO, CastroFB, ShandWJ, OrskovER. (1998) Chemical composition, in sacco degradation and in vitro gas production of some Ghanaian browse plants. Animal Feed Science and Technology, 76, 129–138.
11.
SonibareMA, JiayeolaAA, EgunyomiA. (2005) Chemotaxonomic significance of leaf alkanes in species of Ficus (Moraceae). Biochemical Systematics and Ecology, 33, 79–86.
12.
RajabMS, CantrellCL, FranzblauSG, FischerNH. (1998) Antimycobacterial ativity of (E)-phytol and derivatives: a preliminary structure-activity study. Planta Medica, 64, 1, 2–4.
13.
SantosFA, RaoVSN. (2000) Antiinflammatory and antinociceptive effects of 1,8-cineole a terpenoid oxide present in many plant essential oils. Phytotherapy Research, 14, 240–244.
14.
British Pharmacopoeia. (1980) H.M Stationary Office, Vol II, London, p A109.
15.
AdamsRP. (1995) Identification of Essential Oil Components by Gas Chromatography/Mass Spectroscopy, Allured Publishing Corporation, Carol Stream, Illinois.
16.
SahmDH, WashingtonJA. (1991). Antibacterial susceptibility tests: Dilution methods. In: ‘Manual of Clinical Microbiology’, BalowsA, HauslerWJ, HerrmannKL, IsenbergHD, ShamodyHJ (Eds), American Society for Microbiology, Washington DC, USA.
