The roots of Casearia multinervosa (Flacourtiaceae/Salicaceae) have yielded the new compounds 10ε-acetoxyhumula-3,7-diene (1), (rel)-(2S,5S,6S,8R,9R,10S)-6-hydroxy-2-(2-methylbutanoyloxy)-clero-3,13(16),14-trien-4,5-dial (2), (rel)-(2R,5R,6R,8S,9S,10R)-6-methoxy-2-(2-methylbutanoyloxy)-clero-3,13(16),14-trien-4,5-dial (3), (rel) (2S,5S,6S,8R,9R,10S, 18R,19S)-18-acetoxy-18,19-epoxy-6-hydroxy-2-(2-methylbutanoyloxy)-19-methoxyclero-3,13(16),14-triene (4), and 3ε-(hexadec-11-enyl)-4ε-hydroxy-5-methylene-2,3-dihydrofuran-2-one (5).
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