Two new C18-diterpenoid alkaloids, piepunendines A (1) and B (2) were isolated from the roots of Aconitum piepunense. Their structures were established on the basis of spectral data (1H and 13C NMR, 2D NMR, HR ESIMS). Piepunendine B is the first naturally occurring C18-diterpenoid alkaloid having the 2-(p-hydroxyphenyl)ethoxy group at C-8.
YangQE. (1999) Taxonomic notes on some species of Aconitum L. (Ranunculaceae) from Yunnan, China Acta Phytotaxonomica Sinica, 6, 514–544.
2.
CaiL, ChenDL, LiuSY, WangFP. (2006) Two new C19-diterpenoid alkaloids from Aconitum piepunense. Chemical & Pharmaceutical Bulletin, in press.
3.
PelletierSW, ModyNV, JoshiBS, SchrammLC. (1984) 13C and proton NMR shift assignments and physical constants of C19-diterpenoid. In “Alkaloids: Chemical and Biological Perspectives”, Vol. 2 ed. by PelletierSW, Wiley, New York, pp. 205.
4.
XieGB, WangFP. (2003) New C19-diterpenoid alkaloids from Aconitum liljestrandii, Heterocycles, 60, 631–636.
