Division of Cytokines Into Th1/Th2: A Word of Caution

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Challis JR , Lockwood CJ , Myatt L. , Norman J. , Strauss JF , Petraglia FP Inflammation and pregnancy. Reprod Sci. 2009 ; 16(2):206-215.

Zhu J. , Paul WE CD4 T cells: fates, functions, and faults. Blood. 2008;112(5):1557-1569.

Zhang S. , Wang Q. Factors determining the formation and release of bioactive IL-12: regulatory mechanisms for IL-12p70 synthesis and inhibition. Biochem Biophys Res Commun. 2008;372(4);):509-512.

Naugler WE , Karin M. The wolf in sheep’s clothing: the role of interleukin-6 in immunity, inflammation and cancer. Trends Mol Med. 2008 ;14(3):109-119.

Acosta-Rodriguez EV , Napolitani G. , Lanzavecchia A. , Sallusto F. Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Med. 2007; 8(6):942-949.

Overwijk WW , Schluns KS Functions of γC cytokines in immune homeostasis: current and potential clinical applications. Clin Immunol. 2009;132(2):153-165.

Carroll HP , Pauovic V. , Gadina M. Crossed signals: the role of interleukin-15 and -18 in autoimmunity. Rheumatology. 2008; 47(9):1269-1277.

Halonen M. , Lohman IC , Stern DA , et al. Th1/Th2 patterns and balance in cytokine production in the parents and infants of a large birth cohort. J Immunol. 2009;182(5):3285-3293.