Abstract
Background:
Information technology can be used to improve the management of non-communicable diseases, such as diabetes. This study aims to evaluate the willingness of older outpatients with type 2 diabetes to use mobile phones to support medication adherence and receive text message appointment reminders and investigated the factors associated with this willingness.
Methods:
This study was a cross-sectional study conducted at the outpatient department of Dong Da General Hospital. Participants aged 60 and over managed and treated for type 2 diabetes were asked about mobile phone usage. Data were also collected on sociodemographic information, diabetes characteristics, and medical history.
Results:
In the 584 study participants recruited, the mean age was 73.2 (SD: 8.3) years. Approximately 80% patients with diabetes had medium or high treatment adherence and 52.4% had hemoglobin A1c (HbAlc) < 7.5%. In the multilevel logistic regression analysis, the following factors were significantly associated with willingness to using phones to support medication adherence: college, university, or higher level (odds ratio [OR] = 2.35, 95% confidence interval [CI] = 1.10, 4.99), current smoking (OR = 5.40, 95% CI = 1.01, 28.94), whether they had a mobile phone and type of phone (basic phone: OR = 2.47, 95% CI = 1.42, 4.30; smartphone: OR = 17.93, 95% CI = 8.81, 36.47) . The following factors were significantly associated with willingness to receive these appointment reminders via mobile phone: whether they had a mobile phone and type of phone (basic phone: OR = 2.79, 95% CI = 1.70, 4.59; smartphone: OR = 9.61, 95% CI = 4.61, 19.99) and HbA1c < 7.5 (OR = 0.65, 95% CI = 0.43, 0.99).
Conclusions:
Our study would suggest that there is potential value in using mobile phone to improve the management of diabetes in community living older people but this alone cannot be relied upon.
Introduction
In recent years, although infectious diseases have caused many difficulties and challenges for health systems, economies, and societies around the world, non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, cancer, and chronic lung disease now account for approximately 60% of all deaths worldwide. 1 According to worldwide estimates by the International Diabetes Federation (IDF), in 2019, there were about 463 million people aged 20 to 79 years old with diabetes (9.3%). 2 This was estimated to increase to 578 million people (10.2%) by 2030 and 700 million (10.9%) by 2045. 2 Vietnam is in a period of epidemiological transition with the burden of NCDs, especially diabetes, increasing rapidly. 3
Diabetes prevention and management is one of the National Health Target Programs in Vietnam. Patient adherence to diabetes treatment and engagement with providers of diabetes care is one of the key strategies of this program. Currently, adherence with best practice diabetes management is poor for a large proportion of the population in Vietnam. 4 In addition, Vietnam has a rapidly aging population and as a result the prevalence of older people with diabetes is increasing. Strategies to improve adherence with diabetes management and comprehensive geriatric assessment in Vietnam therefore need to account for the needs of older people. 4
Information technology can be used to improve the management of NCDs, such as diabetes. 5 - 8 There have been several studies that have investigated the use of information technology in the management of sending text message services (SMSs) NCDs. Saleh et al 9 investigated the value of SMS to 1000 patients with NCDs. They found that 93.9% of patients found receiving text messages useful, and easy to read and understand. This intervention resulted in a decrease in the complications caused by treatment of diabetes and hypertension. A relatively simple intervention, such as text message information, can be used to improve adherence with diabetes management. 9
Despite rapid advances in health care technology, older people often face challenges and barriers in using this technology due to physical impairment (poor vision or poor motor control), cognitive difficulties, lack of technological skills, and lack of perceived ability and time. 10 It is therefore important to know more about the perspectives of older people toward adopting new technology-based interventions aimed at improving the adherence with the treatment of chronic conditions, such as diabetes. Therefore, we conducted a study to evaluate the willingness of older outpatients with diabetes to use mobile phones to support medication adherence and receive appointment reminders by mobile phone text message and investigated the factors associated with this willingness.
Material and Methods
Research Design and Location
This study was a cross-sectional study conducted at the outpatient Diabetes Clinic of the Department of Medical Examination, Dong Da General Hospital, from September 2020 to August 2021.
Participants
The study participants were selected through convenience sampling based on whether they met the following inclusion criteria: managed and treated for type 2 diabetes as an outpatient at the hospital for at least one year, aged 60 years and above, able to hear and respond to interview questions and willing to participate in the study.
Data Collection
Data were obtained from face-to-face interviews and audit of medical records.
Data from face-to-face interviews
Participants were interviewed using a pre-designed questionnaire. The interviews were conducted in a separate room and lasted from 10 to 15 minutes. Willingness to use a mobile phone to receive messages to support medication adherence and reminders about next clinic appointments was determined using the following questions, respectively: are you willing to use a mobile phone to receive messages to remind you about your medication schedule? (yes/no) and would you like to receive text messages about your next clinic appointment via a mobile phone (yes/no).
Current Diabetes Treatment adherence was classified based on the Morisky Medication Adherence scale. 11 This questionnaire includes eight items, the first seven being dichotomous (yes/no) to identify adherence or non-adherence. The eighth question asks patients to respond using a five-point Likert scale. The total score ranges from 0 to 8 points. Scores ranging from 0 to 5 were classified as low treatment adherence, 6 as medium treatment adherence, and 7 to 8 as high treatment adherence. This scale has been validated in Vietnamese and it is short and suitable for this study. 12 The Cronbach alpha of this is 0.6.
Participants were asked about mobile phone usage. This included questions about whether they used or owned a mobile phone, if so, whether it was a basic phone (only call and text messages function) or smartphone (call, text, network connection allowing access to internet, and able to use email application) and whether they used the following features on the phone: Wi-Fi, text message, internet, or email.
The following sociodemographic information was obtained: age group (60-69, 70-79, and 80+ years old), gender (male/female), educational level (secondary school or lower/high school/college, university or higher), income level (lowest quartile/second quartile/third quartile/highest quartile), alcohol consumption status (not drinking/occasionally drinking/drinking one to two glasses daily), and smoking status (never smoker/former smoker/current smoker).
Cognitive was assessed by Mini-Cog test (three word recall, and clock drawing and three word recall). 13
Data collected from medical records
Diabetes control was determined based on HbA1c, where <7.5% indicated good control and >7.5% indicated poor control. 14 Hemoglobin A1c was collected from routine blood test results at the most recent time point within three months prior to the time of recruitment.
The following medical information was obtained: number of other chronic diseases (< 2/≥ 2), duration of diabetes illness (< 10 years/≥ 10 years), treatment method (only medication/only insulin injection/both medication and insulin injection).
Statistical Analysis
Descriptive analysis was employed to determine the frequency distribution of categorical variables. Multivariate logistic regression was utilized to identify factors associated with (1) willingness to utilize mobile phones for medication adherence support and (2) the willingness to receive text message appointment reminders via phone as dependent variables in separate models. Variables that have been demonstrated to be associated with these variables in previous studies or “a priori” hypothesis were considered independent variables and included in the models.10,15 Statistical analysis was performed using STATA 15. In this study, a significance level of .05 was used for all statistical tests.
Research Ethics
The study was conducted in accordance with the Declaration of Helsinki and ethics approval was obtained from the Hanoi Medical University (decision no. 241/GCN-HDDDCNCYSH-DHYHN dated November 17, 2020). Written informed consent was obtained from all participants or their representatives/guardians. Participants could withdraw their consent at any time. Participant information was kept confidential and used only for research purposes.
Results
Table 1 shows the characteristics of the included 584 study participants. The mean age was 73.2 (8.3) years old. Prevalence of good HbA1c control was 52.4% and approximately 80% of participants had medium or high treatment adherence.
Characteristics of Study Participants (n = 584).
Among all participants, 241 (41.3%) were willing to use a mobile phone to support medication adherence and 239 (40.9%) were willing to use mobile phone to receive appointment reminders by text message (Table 2).
Mobile Phone Usage Pattern in Study Population.
Table 3 shows the factors associated with willingness for using mobile phones to support medication adherence. In the multilevel logistic regression analysis, aged ≥ 80 (odds ratio [OR] = 2.15, 95% confidence interval [CI] = 1.10, 4.20), education level (college, university, or higher: OR = 2.35, 95% CI = 1.10, 4.99), smoking status (current smokers: OR = 5.40, 95% CI = 1.01, 28.94), whether they had a mobile phone and type of phone (basic phone: OR = 2.47, 95% CI = 1.42, 4.30; smartphone: OR = 17.93, 95% CI = 8.81, 36.47) were significantly associated with willingness for using phones to support medication adherence. There was no statistically significant association between the treatment adherence or diabetes control status and willingness for using mobile phones to support medication adherence.
Factors Associated With Willingness for Using Mobile Phones to Support Medication Adherence Among All Participants (n = 584).
Abbreviations: aOR = adjusted odds ratio; OR = odds ratio; CI = confidence interval; VND = Vietnam Dong.
p < 0.05.
Table 4 shows the multilevel logistic regression analysis of factors associated with willingness to receive reminders about next clinic appointment via mobile phone text. Willingness to receive these reminders via mobile phone was significantly associated with the whether they had a mobile phone and type of phone (basic phone: OR = 2.79, 95% CI = 1.70, 4.59; smartphone: OR = 9.61, 95% CI = 4.61, 19.99), diabetes control status (HbA1c < 7.5%: OR = 0.65, 95% CI = 0.43, 0.99).
Factor Associated With Willingness to Receive Reminder About Next Clinic Appointment Via Mobile Phones Text Messages Among All Participants (n = 584).
Abbreviations: aOR = adjusted odds ratio; OR = odds ratio; CI = confidence interval; VND = Vietnam Dong.
Discussion
Our study of older patients with diabetes found that around a third did not use a mobile phone. We found that age, educational level, smoking status, and whether they had a mobile phone and type of phone (basic or smart) were significantly associated with willingness to receive messages to remind them about their medication schedule. Whether they had a mobile phone and type of phone (basic or smart) were significantly associated with willingness to receive text message appointment reminders.
Mobile Phone Usage Overview
The proportion of participants in our study using smartphone to connect to the Wi-Fi for searching information on the internet was lower than in study conducted in Iran. 15 This may be explained by the fact that the average age of the population in our study (73.2 ± 8.3) was higher than the study in Iran (53.18 ± 15.5). Almost a half of participants used text message, but a lower proportion used email. Of those with mobile phone, a larger proportion made phone calls with it suggesting that voice calls could be used to support medication adherence and remind people about future clinic appointments. Current smoking was significant associated with the willingness to use a mobile phone to support medication adherence in our study. This is an unexpected finding. This relationship could be further explored with qualitative studies. We speculate that some smokers may think that if they are more compliant with diabetes treatment this may counter the adverse effects of smoking.
Medication Adherence
A large proportion of participants (41.3%) were willing to use mobile phone to support medication adherence. Not surprisingly, a higher level of education was associated with a greater willingness to use mobile phones to support medication adherence. Similarly, findings from Ethiopia also indicated that higher education was positively associated with willingness to use a mobile phone.16,17 The percentage of participants willing to use mobile phones to support medication adherence was consistent with other studies from the United States (56.7%) 18 and Japan (50%). 19
Appointment Reminders
Having any mobile phone (compared with no phone) was significantly associated with willingness to clinic appointment reminders via receive text messages and having a smart phone compared with basic phone was associated with higher odds of this willingness.
Implications for Mobile Phone-Based Interventions for Medication Adherence
Our study suggests that there may be value in designing a mobile phone based app that can be used to provide information to enhance diabetes self-management, diabetes management adherence, and clinic follow-up attendance. This particularly applies to older people with higher education and access to smartphones. Our study, however, also shows that we need to think about ways to achieve these outcomes, which does not rely only on mobile phone technology as a large proportion of our participants did not have a mobile phone. Even among those who had a mobile phone many did not use their mobile phone for anything but voice calls. For mobile phone technology to reach a broader audience, health care providers may need to implement educational interventions on use of mobile phones and consider simpler reminder options, such as voice calls, for those less comfortable with digital platforms. It is important to consider sociodemographic characteristics and affordability of mobile phone usage as these are important consideration in older people adapting to digital technology. 20
Strengths and limitations
The strengths of our study were that it was conducted in a general hospital outpatient clinic with a large number of patient visit. However, there are a number of limitations of the study. The study was conducted during COVID-19 period, thus, we could not reach all outpatients with diabetes. Our findings about factors associated with willingness to use mobile phone technology are based on regression analysis of cross-sectional data rather than longitudinal data. But we tend to do a longitudinal study on this population in the future. In addition, the study population was from an urban area. Our findings are specific to a Vietnamese population, so that, cultural differences might limit the generalizability of our findings to older people in other countries.
Conclusions
Our study would suggest that there is potential value in using mobile phone technology to improve the management of diabetes in community living older people but this alone cannot be relied upon.
Footnotes
Acknowledgements
The authors are genuinely thankful to all the participants who gave their time to participate in this study.
Abbreviations
IDF, International Diabetes Federation; NCDs, non-communicable diseases; SMS, sending text message services; VND, Vietnam Dong
Declaration of Conflicting Interests
The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Funding
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: One of the co-authors— TTHN was funded by the Master, PhD Scholarship Program of Vingroup Innovation Foundation (VINIF), code VINIF.2023.TS.122.
Data Availability
The data sets of this study are available from the corresponding author on reasonable request.
