PRE-MEETING COURSE: THE PAEDIATRIC KNEE. TRAUMATIC INJURIES
AUDITORIUM CARSTENSEN
Chairs: Martin Gottliebsen(Denmark),
Marco Turati(Italy)
12:00 Introduction
Marco Turati(Italy)
SESSION 1: PATELLO-FEMORAL INSTABILITY
Chairs: Martin Gottliebsen(Denmark),
Julio Duart(Spain)
12:10 Epidemiology and aetiology. Treatment of first time dislocation
Jaakko Sinikumpu(Finland)
12:20 Imaging, measurements and classifications in
PF instability
Nicolas Nicolau(UK)
12:30 Surgical procedures according to growth potential
Daniel Green(USA)
12:45 MPFL and medial quadriceps tendon-femoral ligament for PFI: Surgical technique and outcomes
Mininder Kocher(USA)
13:00 How to manage MPFLR failures?
Franck Accadbled(France)
13:10 Discussion
SESSION 2: OSTEOCHONDRITIS DISSECANS
Chairs: Nicolas Nicolau(UK),
Jaakko Sinikumpu(Finland)
13:25 Epidemiology, aetiology and natural history
Marco Turati(Italy)
13:35 Imaging and instability concept & criteriae
Franck Accadbled(France)
13:45 OCD of medial femoral condyle: Surgical strategies
Joao Cabral(Portugal)
13:55 OCD in lateral femoral condyle / patella / trochlea / tibial plateau: How to treat them?
Julio Duart(Spain)
14:05 News from the ROCK Study Group
Mininder Kocher(USA),
Daniel Green(USA)
14:20 Discussion
SESSION 3: PEDIATRIC ACL I
Chairs: Luca Rigamonti(USA), Marco Turati(Italy)
15:00 Epidemiology, diagnostic process and imaging
Julio Duart(Spain)
15:10 Non operative management: How?
Indications and risks
Nicolas Nicolau(UK)
15:20 Transphyseal or all-epiphyseal ACL reconstruction? The battle
Franck Accadbled(France),
Nicolas Nicolau(UK)
15:30 Extraphyseal ACL reconstruction
Mininder Kocher(USA)
15:45 Quadriceps tendon autograft in skeletally
ACL reconstruction
Daniel Green(USA)
16:00 Discussion
SESSION 4: PEDIATRIC ACL II
Chairs: Joao Cabral(Portugal), Jaakko Sinikumpu(Finland)
16:10 Is there a role of lateral tenodesis in children with ACL injuries?
Daniel Green(USA)
16:20 ACL tears and associated lesions in skeletally immature patients
Marco Turati(Italy),
Luca Rigamonti(USA)
16:30 ACL Injury prevention programs in pediatric sports
Barbara Kwiatkowski(Switzerland)
16:40 Pediatric ACL rerupture: Risk factors and management
Mininder Kocher(USA)
16:50 Discussion
SESSION 5: MENISCAL INJURIES
Chairs: Franck Accadbled(France), Martin Gottliebsen(Denmark)
17:00 MRI: Anatomical and pathologic characteristics in traumatic meniscal tears
Joao Cabral(Portugal)
17:10 Epidemiology, aetiology and physical examination
Manoj Ramachandran(UK)
17:20 Surgical management of traumatic meniscal tears
Manoj Ramachandran(UK)
17:30 Rehabilitation, return to play and performance after ACL reconstruction
Jaakko Sinikumpu(Finland)
17:40 Discussion
THURSDAY, APRIL 7, 2022
OLI
TIVOLI CONGRESS HALL
BASIC SCIENCE
Chairs: Darko Anticevic(Croatia),
Joachim Horn(Norway)
Moderator: Federico Canavese(France)
08:20 Can manipulation of the mechanical
OP-001 environment improve regenerate
bone healing during the consolidation phase of distraction osteogenesis?
Christopher Iobst, Vaida Glatt, Anirejuoritse Bafor, Mikhail Samchukov, Alex Cherkashin, Satbir Singh (USA)
08:25 The influence of transepiphyseal implantation
OP-002 of Mg-Zn-Ca screws on the growth plate of growing sheep
Romy Marek, Valentin Herber, Patrick Holweg, Maxim Honea, Annelie Martina Weinberg (Austria)
08:30 Changes in the avascular area of the meniscus
OP-003 using growth plate chondrocytes in a pig model
Ryszard Tomaszewski, Magdalena Rost- Roszkowska (Poland)
08:35 Uncovering pathways regulating
OP-004 chondrogenic differentiation of CHH
fibroblasts
Alzbeta Chabronova1, Guus van den Akker1, Mandy Meekels-Steinbusch1, Franziska Friedrich2, Andy Cremers1, Don Surtel1, Mandy Peffers3, Lodewijk van Rhijn1, Ekkehart Lausch2, Bernhard Zabel2, Marjolein Caron1, Tim Welting1
(1The Netherlands, 2Germany, 3UK)
08:40 Discussion
08:50 Anatomical variations of the lateral
OP-005 cutaneous femoral nerve in a paediatric population - an in vivo study
Line Kjeldgaard Pedersen, Lise Larsen, Ole Rahbek, Bjarne Moeller-Madsen (Denmark)
08:55 Systematic isolation of key parameters
OP-006 for estimating skeletal maturity on AP wrist radiographs
Ryan Furdock, Lauren Huang, James Sanders, Daniel Cooperman, Raymond Liu (USA)
09:00 Immersive VR increased the pain threshold
OP-007 and reduced anxiety in children Lucas Yang Vincents Fisker, Line Kjeldgaard Pedersen, Jan Duedal Rölfing, Alexander Juan Møller-San Pedro, Peter Ahlburg, Mette Veien, Lene Vase, Bjarne Moeller-Madsen (Denmark)
09:05 An ovine study of retrograde femoral nail
OP-008 removal with and without fat grafting across the open distal femoral physis
Kouami Amakoutou, Alex Benedick, Derrick M. Knapik, Lewis Zirkle, James M. Anderson, Raymond Liu(USA)
09:10 Discussion
TIVOLI CONGRESS HALL
BEST OF LOWER LIMB DEFORMITY
Chairs: Jaroslaw Czubak(Poland), Mark Eidelman(Israel)
Moderator: Javier Downey(Spain)
09:20 The long-term effect of femoral leg
OP-009 lengthening on muscle strength - a 10 year follow-up
Bernhard Speth, Corina Nüesch, Petros Ismailidis, Marc Schmid, Andreas Krieg (Switzerland)
09:25 The Precice plate: An initial experience
OP-010 Claire Shannon, Aaron Huser, Dror Paley
(Poland)
09:30 How balance changes during growth in
OP-011 pediatric patients: The role of age and patient anthropometry
Luca Rigamonti1,2, Marco Turati2,
Massimiliano Piatti2, Diego Gaddi2, Carlo Alberto Augusti2, Andrea Riganti2, Marta Gandolla2, Giovanni Zatti2, Aaron Krych1, Todd Milbrandt1, Marco Bigoni2(1USA, 2Italy)
09:35 Discussion
09:50 The utility of the modified Fels knee skeletal
OP-012 maturity system in limb length prediction Ryan Furdock, Elizabeth Cho, Alex Benedick, Jiao Yu, Abdus Sattar, Raymond Liu (USA)
09:55 Congenital pseudarthrosis of the tibia: Rate
OP-013 and time to bone union following contralateral vascularized tibial periosteal graft transplantation in 29 cases
Francisco Soldado, Paula Diaz-Gallardo, Jorge Giménez Knorr (Spain)
10:00 Congenital posteromedial bowing of the tibia:
OP-014 Comparison of early and late lengthening
Bhushan Sagade, Naeem Jagani, Ishani
Chaudhary, Milind Chaudhary (India)
10:05 Discussion
TIVOLI CONGRESS HALL DEVELOPMENTAL DYSPLASIA OF THE HIP
Chairs: Andreas Roposch(UK),
Ole Rahbek(Denmark)
Moderator: Renata Pospischill(Austria)
10:55 Outcomes following the management of
OP-016 infant immature hips in a selective screening pathway
11:00 Infants with clinical instability of hip should
OP-017 be seen by 2 weeks of age
Hean Wu Kang, Aidan Cosgrove (Ireland)
11:05 Children’s Hip Predictive Score (CHiP): A OP-018 triage tool for predicting dislocations in
children referred with hip dysplasia
Evelyn Murphy, Catherine Howell, Olga Gallagher, Paula Kelly, Patrick O’Kelly, Jacques Noel, David Moore, Patrick O’Toole, Jim Kennedy (Ireland)
11:10 Discussion
11:25 Outcomes of treatment for developmental
OP-019 dislocation of the hip when the Pavlik method has failed
Carlos Pargas, Karim Masrouha, Cordelia
Carter, Pablo Castaneda(USA)
11:30 Bilaterality: What influence on the prognosis
OP-020 of developmental hip dysplasia?
Cristina Alves, André Carvalho, Ines Balacó, Pedro Sá Cardoso, João Cabral, Oliana Madeira Tarquini, Marcos Carvalho, Tah Ling (Portugal)
11:35 The clinical significance of infolded limbus
OP-021 on post-reduction arthrogram in developmental dysplasia of the hip William Morris, Sai Chilakapati, Sean Hinds, John Anthony Herring, Harry K.W. Kim (USA)
11:40 Brace treatment does not improve acetabular
OP-022 coverage or reduce the rate of secondary surgery following closed reduction of developmental dysplasia of the hip
14:50 Treatment of hip instability in children with
OP-023 Down syndrome: Keys to managing a challenging problem
Jessica Hughes, James Bomar, Dennis
Wenger, Vidyadhar Upasani(USA)
14:55 The first North American hip surveillance
OP-024 program: Enrollment after five years Stacey Miller, Jennifer Farr, Kit Johnson, Kishore Mulpuri(Canada)
15:00 Acetabular retroversion in juveniles
- Mostly
OP-025 caused by a reduced lumbo-pelvic angulation Heimkes Bernhard, Frimberger Vincent, Berger Nina, Hiener Ursula (Germany)
15:05 Discussion
15:15 Two surgical alternatives for Perthes disease: OP-026 Intertrochanteric osteotomy vs. trochanteric
tethering
Peter Stevens, Olivia Grothaus (USA)
15:20 Publication bias in orthopedics: A study on
OP-027 the reporting of positive outcomes in Legg- Calvé-Perthes disease
Peter Filtes, Timothy Roberts, Keenan Sobol,
Pablo Castaneda(USA)
15:25 Effectiveness of triple pelvic osteotomy in
OP-028 patients with Legg-Calve-Perthes disease.
Results of minimum 10 years follow up Cemalettin Aksoy, Elchin Orujov, Vugar Nabϊ, Guney Yilmaz, Aykut Kocyigit (Turkey)
15:30 Discussion
TIVOLI CONGRESS HALL HIP 2
Chairs: Andrzej Grzegorzewski(Poland),
Nicolas Nicolau(UK)
Moderator: Stefan Huhnstock(Norway)
15:40 Femoroacetabular impingement in the
OP-029 unpinned contralateral hip in patients with primary unilateral slipped capital femoral epiphysis - preliminary radiographic outcomes
Magdalena Kwiatkowska, Marcin Kwiatkowski, Maria Czubak-Wrzosek, Jaroslav Czubak, Marcin Tyrakowski (Poland)
15:45 What is the AVN rate of SCFE patients with
OP-030 complete epi-metaphyseal discontinuity treated with the modified Dunn procedure? Kai Ziebarth, Thoralf Liebs, Nadine Kaiser, Klaus-Arno Siebenrock, Till Lerch (Switzerland)
15:55 Discussion
16:00 Is hip dysplasia associated with trochlear
OP-031 dysplasia in skeletally mature patients?
Andrew Fithian, Ann Richey, Seth Sherman, Kevin Shea, Stephanie Pun(USA)
16:05 Incidence and risk factors of heterotopic
OP-032 ossification in a matched cohort adolescent population undergoing hip arthroscopy
OP-033 replacement in children and adolescents Stefano Stallone, Giovanni Trisolino, Paola Zarantonello, Stefano Lucchini, Giovanni Gallone, Barbara Bordini, Dante Dallari, Francesco Traina (Italy)
16:20 Discussion
TIVOLI CONGRESS HALL SPINE 1
Chairs: Carol Hasler(Switzerland),
Dror Ovadia(Israel)
Moderator: Brice Illharreborde(France)
17:00 The effect of idiopathic scoliosis on epidural
OP-034 use and natural delivery during childbirth - A
matched cohort study
Jeff Kessler, Adam Kessler (USA)
17:05 Younger age at spinal cord detethering is
OP-035 potentially associated with a reduced risk of curve progression in children with early onset scoliosis
Rajiv Iyer, Adam Fano, Hiroko Matsumoto, Rishi Sinha, Benjamin Roye, Michael Vitale, Richard Anderson (USA)
17:10 Pre-operative carbohydrate drink for early
OP-036 recovery in pediatric spine fusion: Randomized control study
Jennifer Bauer, Kathryn Anderson, Eliot B. Grigg (USA)
17:15 Elastic lumbar support versus rigid
OP-037 thoracolumbar orthosis for acute pediatric spondylolysis. A prospective controlled study Ella Virkki, Milja Holstila, Terhi Kolari, Markus Lastikka, Kimmo Mattila, Sari Malmi, Olli Pajulo, Ilkka Helenius (Finland)
17:20 Discussion
17:35 Closed suction wound drain reduces
OP-038 postoperative opioid consumption in adoles-cents undergoing pedicle screw instrumenta-tion for idiopathic scoliosis. A randomized, clinical trial
Linda Helenius1, Paul Gerdhem2, Matti
Ahonen1, Jenni Jalkanen1, Johanna Syvänen1, Ilkka Helenius1(1Finland, 2Sweden)
Lenke, Elizabeth Herman, Afrain Boby, Andrew Luzzi, Peter Newton, Baron Lonner, Michael Vitale, Harms Study Group (USA)
17:45 Association of the LBX1 gene promoter
OP-040 methylation in deep paraspinal muscles of patients with idiopathic scoliosis with dis-ease severity
Piotr Janusz, Małgorzata Tokłowicz, Miroslaw Andrusiewicz, Malgorzata Kotwicka, Tomasz Kotwicki (Poland)
17:50 Discussion
TIVOLI CONGRESS HALL SPINE 2
Chairs: Rene Castelein(The Netherlands),
Muharrem Yazici(Turkey)
Moderator: Ilkka Helenius(Finland)
18:00 Mid- and long-term outcomes of lateral
OP-041 thoracotomy: Does the amount of lung parenchyma resection increase the risk
of scoliosis? A retrospective review of 129 pediatric patients
Riccardo Sacco1, Damien Fron2, Dyuti
Sharma2, Michel Bonnevalle2, Federico
Canavese2(1Italy, 2France)
18:05 Complication risks and costs associated with
OP-042 Ponte osteotomies in surgical treatment of adolescent idiopathic scoliosis:
Insights from a national database Mohammed Shaheen, Jayme Koltsov, Samuel A. Cohen, Joanna Langner, Japsimran Kaur, Nicole A. Segovia, John S. Vorhies(USA)
18:10 Curve characteristics and clinical outcomes in
Joanna Langner, Teeto Ezeonu, Abdul-Lateef Shafau, Japsimran Kaur, Kiley Poppino, Claire Shivers, Sai Chilakapati, Kimberly Hall, Meghan Imrie, Lawrence A. Rinsky, Anthony Riccio, John S. Vorhies(USA)
Edward Compton, Stephen Stephan, Kenneth Illingworth, David Skaggs, Lindsay Andras(USA)
18:35 Do rib or spinal proximal anchors in growing
OP-045 rod constructs yield more length gain over time?
Vivian Chen1, David Skaggs1, Edward
Compton1, Kenneth Illingworth1, John
Smith1, Francisco J. Sanchez Perez-Grueso2, Scott Luhmann1, Michael Vitale1, Mark Erickson1, Pediatric Spine Study Group1, Lindsay Andras1(1USA, 2Spain)
18:40 A comparison of SRS and PROMIS
OP-046 questionnaires in patients presenting with adolescent idiopathic scoliosis
Yousi Oquendo, Nadine Javier, Xochitl Bryson, Joanna Langner, Clayton Maschhoff, Christian Calderon, Ann Richey, John S. Vorhies(USA)
18:45 Discussion
TIVOLI CONGRESS HALL WOW MEETING
19:00 Welcome and Introduction
Daniela Dibello(Italy),
Elke Viehweger(Switzerland),
Antonio Andreacchio(Italy)
19:05 Film WOW
Camila Bedeschi (Brazil)
19:10 Supporting and encouraging female orthope-dic surgeons: Experience in UK
Deborah Eastwood(UK)
19:20 Experience of WOW Italy
Daniela Dibello(Italy)
19:30 A survey of family and changing gender roles of European pediatric orthopedists
Elke Viehweger(Switzerland)
19:40 Mentorship, equity and inclusion programs: North America experience
Jennifer Bauer(USA), Mayse Bouchard(Canada), Jamie Rice Denning(USA)
19:55 Inauguration WOW Europe
AUDITORIUM CARSTENSEN SPORTS 1
Chairs: Nick Sekouris(Greece),
Marco Turati(Italy)
Moderator: Jaakko Sinikumpu(Finland)
14:50 Long-term minimum 15-year follow-up after
OP-047 lateral discoid meniscal preservation surgery in children and adolescents
Laura Lins, Aliya Feroe, Brian Yang, Kathryn Williams, Sophia Kocher, Lyle Micheli, Mininder Kocher(USA)
14:55 Meniscus tears in pediatric patients with
OP-048 ACL injury: Incidence, management, and outcome
Luca Rigamonti1,2, Nathaniel A. Bates1,
Nathan D. Schilaty1, Bruce Levy1, Michael
Stuart1, Marco Bigoni2, Todd Milbrandt1, Aaron Krych1(1USA, 2Italy)
15:00 Delays in anterior cruciate ligament
OP-049 reconstruction are associated with higher rates of meniscus and chondral pathology in skeletally immature patients
Andrew Pennock, Matthew Milewski, Lauren Hutchinson, Patricia Miller, Mininder Kocher (USA)
OP-050 reconstruction in skeletally immature patients: Clinical and patient reported outcomes
Sofia Hidalgo Perea, Danielle E. Chipman, Frank Cordasco, Daniel Green(USA)
15:10 Discussion
15:20 Does harvesting of the semi tendinous tendon
OP-051 really spare the gracilis tendon in pediatric
ACL reconstruction?
Testory Maxime, Cavaignac Etienne, Jérôme
Sales de Gauzy, Franck Accadbled(France)
15:25 Decrease in lateral femoral notch sign depth
OP-052 following ACL reconstruction in pediatric patients
Nicolas Pascual-Leone, Danielle E. Chipman, Daniel Green (USA)
15:30 Pediatric partial ACL tears: Outcomes and
OP-053 management practices
Megan Hannon, Nicholas Sullivan, Emily Chang, Patricia Miller, Melissa Christino, William Meehan (USA)
15:35 Discussion
AUDITORIUM CARSTENSEN SPORTS 2
Chairs: Catharina Chiari(Austria), Franck Accadbled(France) Moderator: Julio Duart(Spain)
15:40 Return to preinjury level of sports and the
OP-054 quality of life after tibial spine avulsion fracture with at least 2 years of follow-up Maija Jääskelä1, Marco Turati2,3, Lasse Lempainen1, Antoine Henri2, Aurelien Courvoisier2,3, Nicolas Bremond2,3, Franck Accadbled1, Jaakko Sinikumpu1(1Finland,
2France, 3Italy)
15:45 Growth physis sparing medial patellofemoral
OP-055 ligament reconstruction in children with open physes
Thomas Kappe, Janina Leiprecht, Thomas
Caffard, Heiko Reichel (Germany)
15:50 Incidence of 2nd surgery after medial
OP-056 patellofemoral ligament reconstruction with osteochondral fracture fixation in pediatric patients after patella dislocation
Alexandra Aitchison, Sofia Hidalgo Perea, Lindsay Schlichte, Daniel Green(USA)
15:55 Discussion
16:05 Technique variation for MPFL reconstruction
OP-057 in skeletally immature patients: Data from the
JUPITER cohort
Benton Heyworth, Sofia Hidalgo Perea,
Daniel Green, Matthew Veerkamp, Eric
Wall, Philip Wilson, Beth Shubin Stein, Shital
Parikh (USA)
16:10 Cartilage repair in the skeletally immature
OP-059 knee: A comparative study of different surgical techniques
Ioannes Melas, Dimitrios Metaxiotis, Michael Iosifidis (Greece)
16:15 Infrapatellar realignment for patellar
OP-060 subluxation in the skeletally immature child
John Handelsman, William Facibene (USA)
16:20 Discussion
AUDITORIUM CARSTENSEN CLUBFOOT
Chairs: Alain Dimeglio(France), Adhiambo Witlox(The Netherlands) Moderator: Julia Funk(UK)
17:00 Gait analysis characteristics in clubfoot
OP-061 relapse
Rachel Goldstein, Melissa Bent,
Maia Hauschild, Adriana Conrad-Forrest, Susan Rethlefsen, Tishya Wren, Bob Kay (USA)
17:05 Weight-bearing computed tomography
OP-062 of the foot and ankle in the pediatric population
Derek Kelly, Hayden Holbrook, Alexander
Bowers, Karim Mahmoud,
Benjamin Sheffer(USA)
17:10 The outcomes of congenital talipes
OP-063 equinovarus: A core outcome set for research and treatment
Yael Gelfer, Donato Giuseppe Leo, Aisling Russell, Daniel Perry, Anna Bridgens, Deborah Eastwood (UK)
17:15 Obesity increases risk for surgical site
OP-064 infections and wound dehiscence after pediatric foot surgery: A retrospective cohort review using the NSQIP-pediatric database
Farzam Farahani, Joel Rodriguez, Dane
Wukich, Jacob Zide, Anthony Riccio(USA)
17:20 Discussion
17:30 Incidence and outcomes of leg length
OP-065 discrepancy in patients with idiopathic club-foot deformity
Maryse Bouchard1, Abdullah Addar1,2
(1Canada, 2Saudi Arabia)
17:35 Sport ability during walking age in children
OP-066 with clubfeet treated with Ponseti method: A case series
Gianluca Testa, Andrea Vescio, Alessia Caldaci, Marco Sapienza, Annalisa Culmone, Vito Pavone (Italy)
17:40 The impact of socio-economic factors on
OP-067 drop-out, relapse and non-compliance during
Ponseti treatment in low- and middle income countries: A scoping review
Manon Pigeolet1,2, Anchelo Vital1, Hassan
Ali Daoud1, Carol Mita1, Blake Alkire1, Daniel Corlew1(1USA, 2Belgium)
17:45 Anterior distal epiphysiodesis as treatment of
OP-068 recurrent equinus deformity in Ponseti treated clubfoot patients
Arnold Besselaar1, Isabelle van Tilburg1,
Tessa van de Kerkhof1, Benedicte Vanwanseele1,2, Lianne Grin1,2, Saskia Wijnands1,2, Marieke van der Steen1(1The Netherlands, 2Belgium)
18:30 The fate of bent telescopic rods in children
OP-072 with osteogenesis imperfecta: Do all bent rods need to be revised?
David Fralinger, Denver Burton, Kenneth Rogers, Richard Kruse, Jeanne Franzone (USA)
18:35 What are the factors predisposing to failure of
OP-073 Fassier-Duval rodding in children with osteo-genesis imperfecta?
Bartosz Musielak, Łukasz Woźniak, Jerzy
Sułko, Artur Oberc, Marek Jozwiak (Poland)
18:40 Discussion
HARLEKIN & COLUMBINE NEUROMUSCULAR 1
Chairs: Thomas Dreher(Germany),
Ana Presedo(France)
Moderator: Christian Wong(Denmark)
14:50 Development of hip displacement in children
OP-074 with cerebral palsy: A longitudinal register study of 1045 children
Philippe Wagner,
Gunnar Hägglund(Sweden)
14:55 Hip development after surgery to prevent hip
OP-075 dislocation in children with cerebral palsy: A longitudinal register study of 252 children
Philippe Wagner, Gunnar Hägglund
(Sweden)
15:00 The incidence of AVN after hip containment
OP-076 surgery in children with cerebral palsy Jeremy Bauer, Ellen Raney, Dennis Roy (USA)
15:10 Discussion
15:15 Practice variation and factors influencing
OP-077 indications for interventions for hip displacement in non-ambulant children with cerebral palsy
Max Mifsud, Unni G. Narayanan, U. Givon, K. Graham, M. Jozwiak, Kishore Mulpuri, Benjamin Shore, T. Theologis, W. Schrader, The CHOP Research Group (Canada)
15:20 Progression of hip displacement after
OP-078 triradiate cartilage closure in non-ambulatory cerebral palsy (CP): Who needs continued radiographic surveillance?
Ali Asma, Armagan Can Ulusaloglu, Michael W. Shrader, Kenneth Rogers, Freeman Miller, Jason Howard(USA)
15:25 Femoral head deformity associated with hip
OP-079 displacement in cerebral palsy: Results at skeletal maturity
Armagan Can Ulusaloglu, Ali Asma, Michael W. Shrader, Kenneth Rogers, Freeman Miller, Jason Howard (USA)
15:35 Discussion
15:40 Observational gait analysis in children with
OP-080 cerebral palsy using the Edinburgh Visual
Gait Score (EVGS) and smartphone based slow-motion video technology: A pilot study
Bhushan Sagade, Alaric Aroojis, Suresh
Chand (India)
HARLEKIN & COLUMBINE NEUROMUSCULAR 2
Chairs: Ignacio Martínez-Caballero(Spain),
Elke Viehweger(Switzerland)
Moderator: Uri Givon(Israel)
15:45 Patients GMFCS III are more susceptible to
OP-081 gait deterioration after single-event multilevel surgery in cerebral palsy
Mauro César de Morais Filho, Marcelo Fujino, Francesco Blumetti, Cátia Kawamura, José Augusto Lopes (Brazil)
15:50 Patients and parents’ satisfaction and self-
OP-082 reported evaluation after single-event multilevel surgery in cerebral palsy
Mauro César de Morais Filho, Francesco Blumetti, Marcelo Fujino, Daniela Maury Benavides, Cátia KawamuraJosé Augusto Lopes (Brazil)
16:00 Discussion
16:05 Relation of the sural nerve and medial
OP-083 neurovascular bundle with the Achilles ten-don in children with cerebral palsy treated by percutaneous Achilles lengthening
Ozan Ali Erdal, Baris Gorgun, Necip Selcuk Yontar, Ali Ege Terzibasioglu, Ilker Abdullah Sarikaya, Muharrem Inan (Turkey)
16:10 Long-term results equinus deformity
OP-084 treatment of the feet by Ulzibat and Strayer surgery methods in children with CP
Paviel Rakhman, Oleksandr Korolkov
(Ukraine)
16:15 Anterior distal femoral hemiepiphysiodesis in
OP-085 children with fixed knee flexion deformities: Where should the screws go?
Akshay Seth1, Patricia Miller2, Colyn
Watkins2, Benjamin Shore2(1Canada, 2USA)
16:20 Early versus late scoliosis correction in
OP-086 duchenne muscular dystrophy (DMD): Comparison of post-operative outcomes in the steroid era
Ali Asma, Armagan Can Ulusaloglu, Michael W. Shrader, William Mackenzie, Robert Heinle, Mena Scavina,
Jason Howard (USA)
16:25 Discussion
HARLEKIN & COLUMBINE TRAUMA 1
Chairs: Pierre Journeau(France), Thomas Wirth(Germany) Moderator: Luis Moraleda(Spain)
17:00 Development of a core outcome set for
OP-088 childhood limb fractures
Ben Marson, Joseph Manning,
Marilyn James, Simon Craxford, Sandeep Deshmukh, Daniel Perry, Benjamin Ollivere (UK)
17:05 Casting, elastic intramedullary nailing, or
OP-089 external fixation for pediatric tibia shaft fracture: Which is the most appropriate treatment? A multicenter study
17:10 Virtual fracture clinic pathway for paediatric
OP-090 fractures: A prospective evaluation of 10,000 patients
Flavia Alberghina, Paula Kelly, Jacques Noel, Carol Blackburn, Turlough Bolger, Patrick Kiely, Jim Kennedy, David Moore, Patrick O’Toole (Ireland)
17:15 Discussion
17:30 Medial epicondyle fractures in
OP-091 children: Operative versus non-operative treatment
Emily Chang, Patricia Miller, Evan Stieler, Benjamin Shore, Carley Vuillermin,
Collin May(USA)
17:35 Operative treatment of supracondylar humerus
OP-092 fractures - do we practice what we preach?
Morten Jon Andersen(Denmark)
17:40 What percent of pediatric femur fractures
OP-093 result from non-accidental trauma?
Hanna Omar, Natalya Sarkisova, Christopher
Lee, Rachel Goldstein(USA)
17:45 Discussion
HARLEKIN & COLUMBINE TRAUMA 2
Chairs: Manuel Cassiano(Portugal), Pierre Lascombes(Switzerland) Moderator: Vito Pavone(Italy)
18:00 Pediatric phalanx fractures: A retrospective
OP-094 study and review of the literature
Stéphanie Schizas, Nicolas Lutz, Elif Vardar, Sophie Mercakert, Pierre-Yves Zambelli, Eri Samara (Switzerland)
18:05 Anesthesia and secondary interventions can
OP-095 be avoided by casting overriding distal metaphyseal radius fractures in children under 11 without reduction in emergency department
Topi Laaksonen1, Nicolas Nietosvaara1, Jani
Puhakka2, Antti Stenroos1, Yrjänä
Nietosvaara1, Jussi Kosola1(1Finland,
2Switzerland)
18:10 Seymour fractures. Better do not
OP-096 underestimate it
Laura M. Perez-Lopez, Isabel Parada- Avendaño, Melisa Stitzman, Maria Luisa Cabrera, Cesar Galo Garcia Fontecha (Spain)
18:15 Epidemiology of pediatric pelvic fractures
OP-097 registered in the Swedish Fracture Register Yasmin Hailer, Lisa Larsson, Olof Wolf (Sweden)
18:20 Discussion
18:35 Predictors of healing in paediatric tibial
OP-098 fractures using the RUST score: A 12 year retrospective review
Antony Roy, Pranai Buddhdev (UK)
18:40 Comparison between two protocols of
OP-099 procedural sedation and analgesia in the treatment of pediatric both-bone forearm
fractures
Joaquín Núñez De Armas, Luis Moraleda Novo, Gaspar González Morán, Enrique Gil Garay (Spain)
18:45 Displaced tibial shaft fractures in children: OP-100 Method of treatment in children weighing
50 kg or more
Dorota Hanf-Osetek, Paweł Bilski, Dawid
Łabądź, Sławomir Snela (Poland)
18:50 Discussion
FRIDAY, APRIL 8, 2022
TIVOLI CONGRESS HALL BEST OF TRAUMA
Chairs: Marcell Varga(Hungary), Yrjana
Nietosvaara(Finland)
Moderator: Annelie Weinberg(Germany)
08:30 The use of clinical photographs and patient
OP-101 reported outcome questionnaire as a tool to predict functional outcome in supracondylar humeral fractures treated operatively
Marie-Caroline Nogaro, Senol Bekmez, Mark Camp, Unni Narayanan (Canada)
08:35 Intramedullary fixation for pediatric femoral
OP-102 nonunion in low- and middle-income countries
Ryan Furdock, Lauren Huang, George Ochenjele, Lewis Zirkle, Raymond Liu (USA)
08:40 Outcomes of suture-button versus screw
OP-103 fixation for pediatric and adolescent syndes-mosis injuries
Emily Chang, Blair Stewig, Amy Steele, Patricia Miller, Dennis Kramer, Yi-Meng Yen, Benjamin Shore, Collin May(USA)
08:45 Discussion
09:00 Diaphyseal forearm fractures treated by bio
OP-104 absorbable intramedullary nailing. Challenges to use the nailing tachnique
Gergő Józsa1, Annelie Martina Weinberg2,
Nicolas Lutz3, Morten Jon Andersen4, Erich
Rutz5, Marcell Varga1(1Hungary, 2Austria,
3Switzerland, 4Denmark, 5Australia,
6Hungary)
09:05 Is the X-ray control 4 weeks after ESIN
OP-105 osteosynthesis of forearm fractures an indis-pensable standard or can it be spared?
Sven-Oliver Dietz, Nora Laubach, Martin
Schwind, Pol Rommens (Germany)
09:10 Complications in elective removal of bone
OP-106 lengthening nails: A report of 225 patients Markus Winther Frost1, Ole Rahbek1, Søren Kold1, Anirejuoritse Bafor2, Molly Duncan2, Christopher Iobst2(1Denmark, 2USA)
OP-124 major to biceps brachii in children with arthrogryposis
Olga Agranovich, Petrova Ekaterina, Sergey
Batkin (Russian Federation)
15:45 Radial club hand treated by ulnarization
OP-125 generation 3: The new centralization Jaroslaw Deszczynski, Tomasz Albrewczynski, Claire Shannon, Dror Paley (USA)
15:50 Discussion
AUDITORIUM CARSTENSEN
STUDY GROUP UPPER LIMB WHICH HAND PATHOLOGIES SHOULD A PEDIATRIC ORTHOPEDIC SURGEON KNOW?
Chairs: Nunzio Catena(Italy),
Sebastian Farr(Austria)
16:00 Trigger thumb
SG-09 Marcos Carvalho(Portugal)
16:09 Ganglion cysts
SG-10 Sebastian Farr(Austria)
16:18 Polydactyly
SG-11 Sergio Martínez(Spain)
16:27 Thumb hypoplasia/abscence
SG-12 Nunzio Catena(Italy)
17:36 Syndactyly
SG-13 Francisco Soldado(Spain)
17:45 Discussion
AUDITORIUM CARSTENSEN STUDY GROUP SPINE
LATE COMPLICATIONS IN PEDIATRIC SPINAL DEFORMITY SURGERY
Chairs: Moyo Kruyt(The Netherlands),
Jorge Mineiro(Portugal)
17:00 Introduction
SG-14 Brice Ilharreborde(France)
17:05 Delayed infection
SG-15 Brice Ilharreborde(France),
Sebastian Pesenti(France)
17:15 Neurological
SG-16 René Castelein(The Netherlands)
17:25 Implant related
SG-17 Ilkka Helenius(Finland),
Muharrem Yazici(Turkey)
17:35 Deformity related
SG-18 Dror Ovadia(Israel)
17:45 Conclusion and take away messages
SG-19 Brice Ilharreborde(France)
HARLEKIN & COLUMBINE
TUMOURS & MISCELLANEOUS
Chairs: Marta Salom(Spain),
Bartu Sarisozen(Turkey)
Moderator: Bartek Kowalczyk(Poland)
15:00 Treatment of aneurysmal bone cysts in the
OP-126 proximal femur in 85 children and adoles-cents: Retrospective multi-center analysis
Lizz van der Heijden1, Thom van Geloven1,
Dietmar Dammerer2, Masood Umer3, Kevin Doering2, C. Soto-Montaya4, Mohamed Mesregah5, Philipp Scheider2, Valentino Coppa6, Tanja Kraus2, M. Haara7, Giovanni Beltrami2, Minna Laitinen7, Domenico Campanacci6, Pieter-Bas de Witte1,
Michiel van de Sande1(1The Netherlands,
2Austria, 3Pakistan, 4Colombia, 5Egypt, 6Italy,
7Finland)
15:05 Efficacy and safety of tranexamic acid in
OP-127 resection and endoprosthetic reconstruction of distal femoral osteosarcomas in
children: A retrospective cohort study Bulent Erol, Omer Sofulu, Ozer Ozturk, Murat Polat, Omer Buyuktopcu, Mehmet Deniz Kesimer (Turkey)
15:10 Treatment of unicameral bone cysts in the
OP-128 proximal femur in 89 children and adolescents: Retrospective multi-center study Thom van Geloven1, Lizz van der Heijden1, Dietmar Dammerer2, Masood Umer3, Kevin Doering2, C. Soto-Montaya4, I. Badr5, Philipp Scheider2, Tanja Kraus2, M. Haara6, Giovanni Beltrami7, Minna Laitinen6, Domenico Campanacci7, Pieter-Bas de Witte1,
Michiel van de Sande1(1The Netherlands,
2Austria, 3Pakistan, 4Colombia, 5Egypt,
6Finland, 7Italy)
15:15 Treatment outcomes of monostotic fibrous
OP-129 dysplasia in the proximal femur in
47 children and adolescents: Retrospective multi-center cohort study
Thom van Geloven1, Maartje Meier1, Dietmar
Dammerer2, Masood Umer3, Kevin Doering2, C. Soto-Montaya4, I. Badr5, Philipp
Scheider2, Tanja Kraus2, M. Haara6, Giovanni Beltrami7, Minna Laitinen6, Domenico Campanacci7, Pieter-Bas de Witte1,
Michiel van de Sande1(1The Netherlands,
2Austria, 3Pakistan, 4Colombia, 5Egypt,
6Finland, 7Italy)
15:20 Discussion
15:35 Can Virtual reality headsets be used safely as
OP-130 a distraction method for paediatric orthopaedic patients? A feasibility study
Karen Shepherd, Yogita Shanmugharaj, Obada Kattan, Michail Kokkinakis (UK)
15:40 Asymmetric growth after percutaneous
OP-131 epiphysiodesis
Hannah Weinmayer, Anne Breen, Harald
Steen, Joachim Horn(Norway)
15:45 Use of resorbable magnesium screws in
OP-132 children: Systematic review of the literature and short-term follow-up from our series Danya Falcioni, Valentina Maestri, Valentino Coppa, Antonio Pompilio Gigante (Italy)
15:50 Discussion
HARLEKIN & COLUMBINE
STUDY GROUP TUMOUR
Chairs: Bartu Sarisozen(Turkey), MIchiel van de Sande(The Netherlands)
16:00 Pyomyositis
SG-20 Marta Salom(Spain)
16:09 Chronic recurrent multifocal osteomyelitis
SG-21 Bartek Kowalczyk(Poland)
16:18 Vertebral infections
SG-22 Ilkka Helenius(Finland)
16:27 Treatment of postoperative and implant
SG-23 related infections
Deborah Eastwood(UK)
16:36 Septic arthritis 2022
SG-24 Dimitri Ceroni(Switzerland)
16:44 Discussion
HARLEKIN & COLUMBINE
STUDY GROUP METABOLICS Expert Panel: Deborah Eastwood(UK), Joachim Horn(Norway), Ralph Sakkers
(The Netherlands), Thomas Wirth(Germany)
17:00 X-linked hypophosphatemic rickets: My best
SG-25 case & my worst case
Gabriel Mindler(Austria)
17:15 Osteogenesis imperfecta: My best case & my
SG-26 worst case
Muharrem Inan(Turkey)
17:30 Spondyloepiphyseal dysplasia: My best case
SG-27 & my worst case
Darko Anticevic(Croatia)
17:45 Larsen syndrome: My best case & my worst
SG-28 case
Valdimir Kenis(Russian Federation)
SATURDAY, APRIL 9, 2022
TIVOLI CONGRESS HALL BEST OF THE BEST
Chairs: Antonio Andreacchio(Italy),
Steven Frick(USA)
Moderator: David M. Farrington(Spain)
08:00 Development of the LIMB-Q Kids: A new
OP-133 patient reported outcome measure for chil-dren with lower limb deformities
Harpreet Chhina, Anne Klassen, Jacek Kopec,
Anthony Cooper(Canada)
08:05 Persistently raised titanium levels in children
OP-134 after spinal instrumentation
Peter John Cundy, Brian Freeman, Georgia
Antoniou, William Cundy (Australia)
08:10 The effect of knee height asymmetry on gait
OP-135 biomechanics
Haluk Altiok, Jeremy Bauer, Jacqueline C. Simon, Abdal Kawaiah, Robert Burnham, Cathleen Buckon, Susan Sienko, Ann Flanagan, Karen Kruger, Joseph Krzak (USA)
08:15 Discussion
08:30 Patient-reported outcomes of over 900 adults
OP-136 who had childhood Legg-Calve-Perthes disease (LCPD)
Harry K.W. Kim, Molly McGuire, Roi Armakias, Michael MIllis, Bella Vakulenko- Lagun (USA)
08:35 Operative treatment of distal tibial epiphyseal
OP-137 fractures with bioabsorbable screws - nine years of experience
Marcell Varga, Tamás Kassai, Gergő Józsa
(Hungary)
08:40 Short bioresorbable intramedullary nailing of
OP-138 severely displaced distal forearm fractures in children - an alternative to K-wires
Marcell Varga, Gergő Józsa, Zsófia Krupa, Tamás Kassai (Hungary)
08:45 Discussion
TIVOLI CONGRESS HALL BEST E-POSTERS
Chairs: Ignacio Sanpera(Spain), Jeff
Sawyer(USA)
Moderator: Martin Gottliebsen
(Denmark)
09:00 Appropriate surgical timing of Salter
EP-07 innominate osteotomy for acetabular dyspla-sia in children
EP-82 with ORIF vs non-op: Equivalent strength, endurance, and kinematics
Clare Kehoe, Roger Widmann, Nicolas Pascual-Leone, David Scher, Emily Dodwell (USA)
09:42 Sprengel deformity - clinical and
EP-84 radiographic outcome following surgical intervention
Antfang Carina, Andrea Laufer, Georg Gosheger, Anna Maria Rachbauer, Gregor Toporowski, Adrien Frommer, Henning Tretow, Robert Rödl, Bjoern Vogt (Germany)
09:45 Discussion
TIVOLI CONGRESS HALL
10:00 PRESIDENTIAL GUEST LECTURE
TIVOLI CONGRESS HALL
11:00 AWARDS 2020, PRO MAXIMIS MERITIS
TIVOLI CONGRESS HALL
12:00 PRESIDENCY TRANSFER
TIVOLI CONGRESS HALL
12:30 CLOSING REMARKS
E-POSTERS
EP-01 Prolonged bisphosphonate therapy in children with severe osteogenesis imperfecta could create intramedullary canal obliteration or sclerosis
Darko Anticevic, Željko Jeleč (Croatia)
EP-02 Progress and recurrence of the disease in dys-plasia epiphesealis hemimelica: A systematic review of literature
Alina Khodorovskaya, Vladimir Kenis, Eugeniy Melchenko (Russia)
EP-03 Allografting is an effective biological method of fixation and increases bone trophicity in osteogenesis imperfecta
Sarah El Yahiaouni, Marine De Tienda, Georges Finidori, Valérie Dumaine, Alina Badina, Stéphanie Pannier, Mathilde Gaume, Zagorka Péjin (France)
EP-04 Role of fibular shortness in genu valgum deformity in multiple hereditary exostosis patients
EP-05 An evidence-based clinical practice guideline for developmental dysplasia of the hip under the age of 1 year. Part 1: Centered hips
Christiaan van Bergen, Pieter-Bas de Witte, Willeboordse Floor, Babette L. de Geest, Margret Foreman - van Drongelen, Bart J. Burger, Yvon Den Hartog, J.H. van Linge, Renske M. Pereboom, Simon Robben, Adhiambo Witlox, Melinda M.E.H. Witbreuk (The Netherlands)
EP-06 Gestational week and sonographic acetabular roof a-angle. A prospective, pilot, cohort of Caucasian - Greek population
EP-08 What is the interobserver reliability of an ultrasound enhanced physical examination
of the hip in infants? A prospective study on the ease of acquisition of skills to diagnose hip dysplasia
Neha Jejurikar, Leon Moscona Mishy, Monica Rubio, Romina Cavallaro, Pablo Castaneda (USA)
EP-09 Development and validation of a diagnostic aid for DDH in early infancy: Building on the results of a multinational EPOS study
Andreas Roposch, Annie Hurley, Rachel Buckingham, Claudia Maizen,
Pranai Buddhdev, Aresh Hashemi-Nejad (UK)
EP-10 Does age at start of treatment have an influ-ence of follow-up development of unstable hips?
Bettina Westhoff, Hannes Kubo, Hakan Pilge, Jan-Philipp Holthoff, Martin Hufeland, Ruediger Krauspe (Germany)
EP-11 AVN: How to minimize it? The effectiveness of Morel progressive traction in DDH (III-IV grade IHDI)
Federica De Rosa, Daniele Sini, Chiara
Arrigoni, Carlo Origo (Italy)
EP-12 Comparison of pubo femoral distances in lat-eral versus supine positioning of the child Hans-Christen Husum, Christian Klitt Jensen, Michel Bach-Hellfritzsch, Mads Henriksen, Ole Rahbek (Denmark)
EP-13 Residual dysplasia in left-sided and right-sided hip dislocation in children with devel-opmental dysplasia of the hip
Hsin-Ying Lin, Suzanne de Vos-Jakobs, Stijn Westerbos, Max Reijman (The Netherlands)
EP-14 Parental experiences of children with develop-mental dysplasia of the hip: A qualitative study Wesley Theunissen, Marieke van der Steen, Florens van Douveren, Adhiambo Witlox, Jaap Tolk (The Netherlands)
EP-15 Traction assisted reduction compared with surgical reduction for treatment of walking age developmental dysplasia of the hip Jason Chinnappa1,2, Anne-Laure Simon1,
Alexandre Gounot1, Philippe Souchet1, Brice
Ilharreborde1(1France, 2Australia)
EP-18 The importance of monitoring and factors that may influence leg length difference in developmental dysplasia of the hip
EP-19 A delayed imaging protocol for risk-factor based screening for developmental dysplasia of the hip reduces treatment rates: A COVID induced study
Anish Sanghrajka, Rajiv Merchant, Rachael
Fisher, Helen Chase (UK)
EP-20 Total hip arthroplasty followed by intramed-ullary femoral lengthening for staged reconstruction of unilateral neglected hip dislocation
Bjoern Vogt, Robert Roedl, Georg Gosheger, Adrien Frommer, Christoph Theil, Gregor Toporowski, Andrea Laufer (Germany)
EP-21 Is the lateral cuneiform large enough to sup-port interference screw fixation for tibialis anterior tendon transfer in children aged 3 to
6 years?
Jordan Polk, Zachary Meyer, Jacob Zide, Yassine Kanaan, Anthony Riccio (USA)
EP-22 The Ponseti method for the treatment of club-feet associated with Down syndrome
Edwin Portalatin-Perez1, Sarah Parenti2,
Jordan Polk2, Chan-Hee Jo2, Anthony Riccio2
(1Puerto Rico, 2USA)
EP-23 Interrelations between the too-long anterior calcaneal process, hind and mid-tarsal bone volumes, angles and osteochondral lesion of the dome of the talus. Analysis by software slicer of 69 CT scan of feet
Giovanni Lucchesi1, François Bonnel2, Alain
Dimeglio2, Giovanni Beltrami1, Federico
Canavese2(1Italy, 2France)
EP-24 Participation and motor abilities in children with idiopathic clubfeet after treatment with the Ponseti method
Arnold Besselaar1, Lianne van Dijk1,
Lianne Grin1,2, Saskia Wijnands1,2, Marieke van der Steen1, Benedicte Vanwanseele1,2(The Netherlands)
EP-25 Atypical triplane fractures in adolescents: How much displacement is acceptable for conservative treatment?
Chaemoon Lim (South Korea)
EP-26 Location of sustentaculum tali on foot AP radiographs reduces the risk of subtalar joint articular facets damage in calcaneal lengthen- ing osteotomy
Sapogovskiy Andrey, Vladimir Kenis
(Russia)
EP-27 Objectively measured sleep metrics in infants and toddlers undergoing night-time boots and bar brace treatment for clubfoot compared to age matched controls
Charlotte Sununu, Natalie Barnett, Clare
Kehoe, David Scher (USA)
EP-28 Efficacy of various treatment strategies in severe Legg-Calve-Perthes Disease: A net-work meta-analysis
EP-30 The optimized Oxford hip skeletal maturity system proves resilient to rotational variation Julio Castillo Tafur, Ryan Furdock, Abdus Sattar, Raymond Liu (USA)
EP-31 Long term follow-up (35 years) of untreated patients with idiopathic increased femoral anteversion
Anders Grønseth, Suki Liyanarachi, Joachim
Horn, Terje Terjesen (Norway)
EP-32 Hip morphology in periacetabular osteotomy patients treated for developmental dysplasia of the hip as infants compared to those with-out infant treatment
Bridget Ellsworth, Joshua Bram, Ernest Sink
(USA)
EP-34 The mini open approach for the correction of femoral-acetabular impingement after a slipped upper femoral epiphysis is effective and reproducible
Karim Masrouha, Pablo Castaneda, Leon
Moscona Mishy, Salim Habib (USA)
EP-35 Testing a new surgical principle of guided growth for correction of rotational deformity of long bones in children
Andreas Peter Balslev-Clausen, Klaus Hindsø, Peter Buxbom, Christian Wong (Denmark)
EP-36 How are pre-operative surgeon and patient expectations related to patient-reported out-comes after periacetabular osteotomy? Samantha Ferraro, Patricia Miller, Michael MIllis (USA)
EP-37 Hip instability in children with trisomy 21
Milud Shadi, Pawel Glowka, Marek Jóźwiak, Tomasz Kotwicki (Poland)
EP-38 An anatomic study of the proximal tibial epiphysis with relevance to percutaneous epi-physiodesis using transphyseal screws Michael Do, Conor McCarthy, Daniel Cooperman, Raymond Liu (USA)
EP-39 Femur lengthening over nail in adolescents: Is the lateral shift of the mechanical axis inevitable?
Kyeong-Hyeon Park1, Chang-Wug Oh2
(1South Korea, 2USA)
EP-40 Drop landing analysis of rotational osteotomies
Peter Stevens, Bruce Macwilliams (USA)
EP-41 Tension band plating for correction of leg length difference
EP-42 Morphology of the knee joint after tension-band plating
Emma Julie Hvidberg, Maria Kirstine Møller- Madsen, Jan Duedal Rölfing, Bjarne Moeller- Madsen, Ahmed A. Abood (Denmark)
EP-43 Our experience of treatment of congenital pseudoarthrosis of tibia using X-union protocol
Petr Vvedenskiy, Maxim Vlasov (Russia)
EP-44 Bone age assessment by 3 methods. A com-parison of 3 different methods for assessment of skeletal age when treating leg length discrepancies: An inter- and intra-observer study Anne Breen, Joachim Horn, Harald Steen,
Are Pripp, Ragnhild Gunderson, Else Merckoll, Ivan Hvid, Wajeeha Zaidi, Hilde Kristine Sandberg Mentzoni (Norway)
EP-46 MPLF reconstruction and hemi-epiphysiode-sis for patellar instability with genu valgum Dayna Philips1, Matthew Veerkamp1, Eric Wall, Matthew Ellington1, Nicole Friel1, John Schlechter1, Daniel Green1, Javier Masquijo2, Shital Parikh1(1USA, 2Argentina)
EP-47 Lengthening of the femur in adolescents with congenital diseases. Comparison of three dif-ferent techniques
Szymon Pietrzak, Dariusz Grzelecki, Tomasz
Parol, Jaroslav Czubak (Poland)
EP-48 Many radiologic indices for patellofemoral instability are unreliable
Peter Fabricant, Madison Heath, Douglas Mintz, Kathleen Emery, Matthew Veerkamp, Simone Gruber, Daniel Green, Eric Wall, Marc Tompkins, Benton Heyworth, JUPITER Study Group, Beth Shubin Stein, Shital
Parikh (USA)
EP-49 Management of first-time patellar dislocation: A survey of PRISM members
Shital Parikh, Matthew Veerkamp, PRISM Patellofemoral RIG (USA)
EP-50 Demographic and clinical characteristics of patellar instability patients from prospective JUPITER (Justifying Patellar Instability Treatment by Early Results) cohort
Meghan Bishop, Jacqueline Brady, Simone Gruber, Matthew Veerkamp, Joseph Nguyen, Benton Heyworth, Marc Tompkins, Daniel Green, Eric Wall, JUPITER Study Group, Beth Shubin Stein, Shital Parikh (USA)
EP-51 Suicidal ideation in pediatric orthopedic patients
Whitney Herge, Farzam Farahani, Aaron Hurd, Claire Shivers, Shelby Cerza, Sarah Parenti, Anthony Riccio (USA)
EP-52 Electromyography role in children with split cord malformation diagnosis
EP-53 Validity of the patient reported outcome information system (PROMIS) in children and adolescents with lower extremity conditions
Nicholas Sullivan, Patricia Miller, Susan Mahan, Samantha Spencer, James Kasser, Matthew Milewski, Dennis Kramer, Collin May (USA)
EP-54 Using a digital inclinometer significantly improves the accuracy of derotation osteot-omy: A simulation study
Anish Sanghrajka, Daniel Watts, Helen
Chase, Daniel Bye (UK)
EP-55 Double calcaneal osteotomy in correction of severe planovalgus foot deformity in ambulatory children with spastic cerebral palsy. A prospective case series study
Ahmad Saeed Aly, Shady Abdelghaffar
(Egypt)
EP-56 Hip displacement in spinal muscular atrophy: The influence of genetic severity and func-tional level
Armagan Can Ulusaloglu, Ali Asma, Michael W. Shrader, Mena Scavina, William Mackenzie, Amanda Erb, Jason Howard (USA)
EP-57 The influence of baseline gait velocity on treatment results after single-event multilevel surgery in patients with cerebral palsy
Mauro César de Morais Filho, Marcelo
Fujino, Francesco Blumetti, Cátia Kawamura, José Augusto Lopes (Brazil)
EP-58 Predictors of postoperative urinary retention after posterior spinal fusion for adolescent idiopathic scoliosis
Tommi Yrjälä, Linda Helenius, Markku Taittonen, Hanna Oksanen, Heli Keskinen, Terhi Kolari, Ilkka Helenius (Finland)
EP-59 Treatment of recurrent patellar dislocation in children and adolescents with medial patel-lofemoral ligament reconstruction - pediatric technique
João Cabral, Ines Balacó, Marcos Carvalho, Oliana Madeira Tarquini, Pedro Sá Cardoso, Tah Ling, Cristina Alves (Portugal)
EP-60 First report and analysis of anterior inferior iliac spine avulsion re-fracture of the hip Javier Besomi, Jose Tomas Bravo, Cristian Olmedo, Jorge Joannon, Daniela Landea, Pedro Salgado (Chile)
EP-62 Fully displaced pediatric supracondylar humerus fractures: Which ones need to go at night?
Susan Mahan, Patricia Miller, Jiwoo Park, Nicholas Sullivan, Carley Vuillermin (USA)
EP-63 Firearm-associated orthopedic injuries in the pediatric population of New York State
(2016-2020)
Cordelia Carter, Charles Lin, Utkarsh Anil
(USA)
EP-64 Global variations in the management of diaphyseal forearm fractures in children: A survey of EPOS and POSNA members
Ludger Tüshaus1, Christoph Roeder2, Annelie
Martina Weinberg2, Louise Klingenberg3, Sven-Oliver Dietz1, Nicolas Lutz4, Federico Canavese5, Cristina Alves6(1Germany,
2Austria, 3Denmark, 4Switzerland, 5France,
6Portugal)
EP-65 Construct validity of a novel simulator for pinning of supracondylar humeral fractures Jan Duedal Rölfing1, Steven Long2, Ahmed A. Abood1, Emily Connor1, Emily
Wagstrom1, Geb Thomas1, Don Anderson1, Heather Kowalski1 (1Denmark, 2USA)
EP-66 Two-fold risk of fractures among children whose mother smoked during the pregnancy Roope Parviainen, Juha-Jaakko Sinikumpu (Finland)
EP-67 Clinical outcome of supracondylar humerus fractures in patients younger than 30 months Ahmet Hamdi Akgülle, Bulent Erol, Yavuz Şahbat, Hayati Kart, Özgür Baysal (Turkey)
EP-69 Surgical exploration of the pink pulseless supracondylar fracture
Philip McKeag, Hean Wu Kang, Richard
Napier (UK)
EP-70 Treatment of unicameral bone cysts: A com-parative study during 8-year period
Bojan Bukva, Sinisa Ducic, Mikan Lazovic, Filip Milanovic (Serbia)
EP-71 Percutaneous alcohol-based sclerotherapy in aneurysmal bone cyst in children and adoles-cents. A retrospective study of 41 patients Maria Tirta, Georgia Antoniou, Anastasia Pilichou1 Panagiotis Krallis, Maria Stefanou, John Anastasopoulos (Greece)
EP-72 The proximal congenital radioulnar synosto-sis: Quality of life of paediatric patients. A multicentre study
Paola Zarantonello, Giovanni Luigi Di Gennaro, Sebastian Farr, Giovanni Trisolino, Diego Antonioli, Giovanni Gallone, Stefano Stallone (Austria)
EP-73 Corrective procedure for flexion contracture of the elbow in neonatal palsy sequelae: Long term follow-up
Filippo M. Senes, Anna Maria Nucci, Annalisa Valore, Nunzio Catena (Italy)
EP-74 The treatment outcome of pediatric trigger thumb: Open surgery versus nonoperative management according to age
Jung Yun Bae, Ju Mi Hwang (South Korea)
EP-75 Temporary epiphysiodesis in adolescent patients with ulnocarpal impaction syndrome
Philipp Scheider, Rudolf Ganger, Sebastian
Farr (Austria)
EP-76 Age-related outcomes and complications of osteodistraction in the pediatric upper extrem-ity: A large retrospective single-center study
of 61 cases
Philipp Scheider, Rudolf Ganger, Sebastian
Farr (Austria)
EP-77 Testing a new method of osteosynthesis of antebrachium fractures in children; A prospective randomized controlled longitudinal study Lærke Gyllenborg, Christian Wong, Ture Karbo (Denmark)
EP-78 Flexor tendon injuries in the pediatric age: What results can be expected?
Marcos Carvalho, Ricardo Marques, Pedro Sá Cardoso, Tah Ling, Ines Balacó, Oliana Madeira Tarquini, João Cabral, Cristina Alves (Portugal)
EP-79 Peripheral nerve injuries of the upper extremity in paediatric population: Long-term outcomes and prognostic factors
Justine Fleurette, Mathilde Gaume, Marine De Tienda, Caroline Dana, Stéphanie Pannier (France)
EP-80 Signaling overuse sports injuries in the pedi-atric elbow: Physicians’ item collection Brinne Roorda, Christiaan van Bergen,
Denise Eygendaal, Bertram The, Iris van Oost
(The Netherlands)
EP-81 Innovation of COVID-19 pandemic; A pro-spective study on paediatric forearm fractures manipulations in A&E department of a District General Hospital
Hafiz Umer, Hafiz-Javaid Iqbal, Matthew Nixon, Mark Webb, Peter Kenyon, Sophie Dodd (UK)
EP-82 Displaced midshaft clavicle fractures treated with ORIF vs non-op: Equivalent strength, endurance, and kinematics
Clare Kehoe, Roger Widmann, Nicolas Pascual-Leone, David Scher, Emily Dodwell (USA)
EP-84 Sprengel deformity - clinical and radiographic outcome following surgical intervention Antfang Carina, Andrea Laufer, Georg Gosheger, Anna Maria Rachbauer, Gregor Toporowski, Adrien Frommer, Henning Tretow, Robert Rödl, Bjoern Vogt (Germany)
EP-85 Measurement for objective diagnosis of multidirectional instability of shoulder in adolescent patients
Mason Yoder, Matthew Veerkamp, Colin
McDonald, Shital Parikh (USA)
Basic Science
OP-001
Can manipulation of the mechanical environment improve regenerate bone healing during the consolidation phase of distraction osteogenesis?
Christopher Iobst1, Vaida Glatt2, Anirejuoritse Bafor1, Mikhail Samchukov3, Alex Cherkashin3, Satbir Singh1
1Nationwide Children’s Hospital, USA, 2UT Health San Antonio, USA, 3Texas Scottish Rite Hospital, USA
Introduction and Objective: Bone healing relies on interplay between biology and the surrounding mechanical environment. Manipulation of the environment can influence bone healing. The concept of reverse dynamization describes starting with relatively flexible fixation around the fracture site and then switching to more rigid fixation once callus formation occurs. In distraction osteogenesis, the consolidation phase is the longest and slowest portion of the treatment. If the bone healing could be accelerated during the consolidation phase, the patient could return to activity/work quicker. This study will evaluate whether reverse dynamization can accelerate the remodeling of bone during the consolidation phase of distraction osteogenesis.
Materials and Methods: 18 male Spanish cross goats underwent 2 cm of limb lengthening using an external fixator to the right tibia. Three different groups of six goats were created based on the connections between the rings: threaded rods or 3D printed dynamizers allowing 2 mm of axial micromotion. The static group had threaded rods the entire time. The dynamized group had the dynamizers the entire time. The reverse dynamized group had the dynamizers during the distraction phase but switched to the threaded rods during the consolidation phase.
Results: Radiographs demonstrate visible difference in the amount and shape of callus between the three groups. Biomechanical testing demonstrates that the reverse dynamized group was stronger than the intact bone and statistically significantly stronger than the other two experimental groups. MicroCT demonstrates statistically significantly lower bone volume, total volume and higher bone mineral density in the reverse dynamized group than the other two experimental groups. Sagittal and axial images through the regenerate demonstrate further remodeling in the reverse dynamized group.
Conclusions: Reverse dynamization accelerates the remodeling and maturation of regenerate bone in distraction osteogenesis in a large animal model. This has tremendous clinical implications for patients undergoing limb lengthening surgery.
Basic Science
OP-002
The influence of transepiphyseal implantation of Mg-Zn-Ca screws on the growth plate of growing sheep
Romy Marek1, Valentin Herber1, Patrick Holweg1, Maxim Honea1, Annelie Martina Weinberg1
1Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria
Introduction and Objective: In order to achieve optimal fracture stabilization transepiphyseal implantation is often unavoidable. The use of bioresorbable implants offers new possibilities. Previously performed pilot study showed, that bioresorbable Mg-Zn-Ca (ZX00) -screws broke several weeks after implantation, allowing physiological bone growth, while titanium (Ti) led to an early closure of the growth plate. The aim of this study was to confirm achieved results with a higher animal number.
Materials and Methods: A short-term and a long-term group was included in this study. For the short-term group six juvenile sheep underwent transepiphyseal implantation of either ZX00- or Ti-screws into the proximal tibia. The sheep were euthanized 24 weeks after implantation. Micro computed tomography (CT) was performed on harvested bones, in order to calculate implant and gas volume. For the long-term group eight sheep were operated in the same manner. In vivo clinical CT was performed 3, 6, 12, 24, 52, 76 and 104 weeks after surgery, in order to follow the in vivo degradation behavior of the implants, as well as bone growth.
Results: In the long-term group all ZX00-screws broke earliest six weeks after implantation. No difference in leg length between ZX00-legs was detected when compared to the empty control legs until two years after implantation. In contrast, Ti-legs were significantly shorter when compared to ZX00-legs, as well as the control legs, two years after implantation. Investigation of µCT data of the short-term group is still ongoing.
Conclusions: The results indicate that transepiphyseal implantation of Ti-screws leads to an early closure of the growth plate, while this is not the case for ZX00-screws. This suggests that ZX00- implants can be used for transepiphyseal fracture stabilization in children.
Basic Science
OP-003
Changes in the avascular area of the meniscus using growth plate chondrocytes in a pig model
Ryszard Tomaszewski1, Magdalena Rost-Roszkowska2
1GCZD, Pediatric Traumatology and Orthopedics, Katowice, Poland, 2Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University, University of Silesia, Katowice, Poland
Introduction and Objective: This study aimed to evaluate autologous growth plate chondrocytes’ impact on the healing process of a damaged meniscus in the avascular zone based on a growing animal model.
Materials and Methods: The study group consisted of 10 pigs at about three months of age. From each animal, chondrocytes from the iliac growth plate and from concentrated bone marrow were taken. Knee joints were divided into right (R) and left (L). The meniscus was damaged in the avascular zone in both knee joints. The medial meniscus of the R knee joint was treated with a hyaluronic acid based scaffold incubated with bone marrow cells from marrow aspirates (nCHON). The medial meniscus of the L knee joint was treated with a hyaluronic acid based scaffold incubated with bone marrow cells from marrow aspirates supplemented with immature chondrocytes isolated from growth plates (wCHON). After three months the animals were euthanized and preparations (microscopic slides) were made from the meniscus’ damaged part.
Results: A qualitative and quantitative analysis have been prepared. The wCHON group in comparison with the nCHON group showed a statistically significantly higher number of fusiform cells on the surface of the graft as well as better healing of the graft. In addition, the degree of vascularization was higher in specimens from the wCHON group than in the nCHON group.
Conclusions: The results of our research on immature pig knees revealed that mesenchymal stem cell and growth plate chondrocytes could be treated as the cell source for meniscus reconstruction, and growth plate chondrocytes enhance healing processes in the avascular zone of the injured meniscus.
Basic Science
OP-004
Uncovering pathways regulating chondrogenic differentiation of CHH fibroblasts
Alzbeta Chabronova1, Guus van den Akker1, Mandy Meekels-Steinbusch1, Franziska Friedrich2, Andy Cremers1, Don Surtel1, Mandy Peffers3, Lodewijk van Rhijn1, Ekkehart Lausch2, Bernhard Zabel4, Marjolein Caron1, Tim Welting1
1Orthopedic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands, 2Department of Pediatrics, University of Freiburg, Freiburg, Germany, 3Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom, 4Medical Faculty, Otto van Guericke University of Magdeburg, Magdeburg, Germany
Introduction and Objective: Mutations in the non-coding snoRNA component of mitochondrial RNA processing endoribonuclease (RMRP) are the cause of cartilage-hair hypoplasia (CHH). CHH is a rare form of metaphyseal chondrodysplasia characterized by disproportionate short stature and abnormal growth plate development. The process of chondrogenic differentiation within growth plates of long bones is vital for longitudinal bone growth. However, molecular mechanisms behind impaired skeletal development in CHH patients remain unclear.
Materials and Methods: We employed a transdifferentiation model (FDC) combined with whole transcriptome analysis (RNAseq) to investigate the chondrogenic trans differentiation capacity of CHH fibroblasts (n = 4) and age-matched controls (n = 4) and to examine pathway regulation in CHH cells during chondrogenic differentiation. Results were validated using RT-qPCR and ELISA.
Results: We established that the FDC transdifferentiation model is a relevant in vitro model of chondrogenic differentiation, with an emphasis on the terminal differentiation phase, which is crucial for longitudinal bone growth. We demonstrated that CHH fibroblasts are capable of transdifferentiating into chondrocyte-like cells, and show a reduced commitment to terminal differentiation. We also found a number of key factors of BMP, FGF, and IGF-1 signalling axes to be significantly upregulated in CHH cells during the chondrogenic transdifferentiation.
Conclusions: Our results support postulated conclusions that RMRP has pleiotropic functions and profoundly affects multiple aspects of cell fate and signalling. Our findings shed light on the consequences of pathological CHH mutations in snoRNA RMRP during chondrogenic differentiation and the relevance and roles of non-coding RNAs in genetic diseases in general.
Basic Science
OP-005
Anatomical variations of the lateral cutaneral femoral nerve in a paediatric population - an in vivo study
Line Kjeldgaard Pedersen1, Lise Larsen1, Ole Rahbek2, Bjarne Moeller-Madsen1
1Children Orthopedics, Aarhus University Hospital, Aarhus, Denmark, 2Children Orthopedics, Aalborg University Hospital South, Aalborg, Denmark
Introduction and Objective: In adult populations, several anatomic studies of the lateral femoral cutaneous nerve (LFCN) have been performed describing numerous anatomic variations. LFCN exits in the majority of cases from the pelvis medial to the anterior superior iliac spine (ASIS) under the inguinal ligament (IL) as a single structure. Iatrogenic damage might cause painful meralgia paresthetica. This condition may be underdiagnosed in paediatric surgery. No dissection studies have been published documenting the paediatric LFCN anatomy in vivo. Hence, the aim of this study is to report in vivo anatomical variations of the LFCN in a paediatric population.
Materials and Methods: Thirty-one children aged 4-14 years of age undergoing pelvic osteotomy (three bilateral) were prospectively included. Standardized peroperative photography of the LFCN was collected. Outcome parameters were pelvic exit, distance from exit to ASIS, and branching patterns and appearance.
Results: 31 nerves (91%) left the pelvis medial to the ASIS under the Sartorius, one nerve (3%) left the pelvis medial to the ASIS but through the IL, one nerve (3%) passed through the ASIS and one nerve (3%) exited lateral to the ASIS. The mean distance from the pelvic exit to the ASIS was 17 mm. Nine nerves (26%) showed no branching, one (3%) had a bifurcation within the pelvis, 12 nerves (35%) showed bifurcation in the IL area, seven (20%) showed trifurcation, two (6%) showed quadrification and three (9%) had a branching pattern of more than four. Nine nerves (26%) had a curved appearance and 25 (74%) had a straight appearance.
Conclusions: The branching pattern of the paediatric LFCN has not previously been documented by an in vivo study. The majority (75 %) of LFCN showed branching. 91 % left pelvis medial to ASIS. Our results call for rewriting anatomic textbooks.
Basic Science
OP-006
Systematic isolation of key parameters for estimating skeletal maturity on AP wrist radiographs
Ryan Furdock1, Lauren Huang1, James Sanders2, Daniel Cooperman3, Raymond Liu1
1Orthopaedic Surgery, Rainbow Babies & Children’s Hospital at Case Western Reserve University, Cleveland, USA, 2Orthopaedic Surgery, University of North Carolina School of Medicine, Chapel Hill, USA, 3Orthopaedic Surgery, Yale School of Medicine, New Haven, USA
Introduction and Objective: The ability to estimate a continuous skeletal maturity from a wrist radiograph would be useful in the treatment of adolescent forearm fractures, scoliosis, and other conditions. We attempted to create a reliable, rapid, and accurate method.
Materials and Methods: Sixty-four AP wrist radiographic parameters from three skeletal maturity systems were simplified to 23 based on relevance to the peripubertal age range, univariate correlation with skeletal maturity, and reliability. These 23 parameters were evaluated on serial peripubertal AP hand-wrist radiographs. We obtained the Greulich and Pyle (GP) skeletal age and Sanders hand system (SHS) stage. We used stepwise linear regression and generalized estimating equation (GEE) procedures to identify important radiographic and demographic parameters for estimating skeletal maturity, creating the “Modified Fels wrist skeletal maturity system.” Its accuracy predicting skeletal maturity was evaluated and compared to four other systems: 1) GP, 2) SHS, 3) age, sex, and GP, 4) age, sex and SHS.
Results: 372 radiographs from 42 girls (range 7-15 years) and 38 boys (9-16 years) were included. Fifteen radiographic parameters were excluded from the Modified Fels wrist system by stepwise regression and GEE analyses, leaving age, sex, and 8 radiographic parameters in the final model. The Modified Fels wrist system made more accurate skeletal maturity estimations (0.33 year mean discrepancy from actual skeletal maturity) than all other systems (p <.001 for all). The Modified Fels wrist system had a similar rate of skeletal maturity estimations with more than one year discrepancy as the age, sex, and SHS model (1.9% vs 3.5%, p = 0.11), and fewer than all other systems (p <.05 for all).
Conclusions: A system of demographics and 8 AP wrist radiographic parameters estimates skeletal maturity more accurately than the two most used skeletal maturity systems.
Basic Science
OP-007
Immersive VR increased the pain threshold and reduced anxiety in children
Lucas Yang Vincents Fisker1,2, Line Kjeldgaard Pedersen1,2, Jan Duedal Rölfing1,2, Alexander Juan Møller-San Pedro1,2, Peter Ahlburg3, Mette Veien3, Lene Vase4, Bjarne Moeller-Madsen1,2
1Department of Orthopaedics, Aarhus University Hospital, Denmark, 2Danish Paediatric Orthopaedic Research, Denmark, 3Department of Anaesthesiology, Aarhus University Hospital, Denmark, 4Department of Psychology and Behavioural Sciences, Aarhus University, Denmark
Introduction and Objective: Can Immersive Virtual Reality (VR) distract children and reduce pain and anxiety? VR is progressively being used in paediatric medical procedures by immersing the child in a 3-dimensional 360° alternate reality, but the effect is still not tested in a well-controlled design. The primary objective was to evaluate if immersive VR can modulate pain threshold (PPT) and anxiety level in children.
Materials and Methods: Seventy-two children (6-14 years old) were included in this cross-over, randomized controlled study comparing VR-Game, VR-Video, Control-Video, and Control. All 72 children were exposed to all four interventions in a randomized sequence. Control for carry-over and time effects was achieved by allocating participants to 24 randomized sequences (n = 3*24 = 72). The study took place in the outpatient clinic, where the children sat on a chair, and no invasive procedures were performed. Validated outcome measures were applied. PPT was assessed with algometry and anxiety level with the modified Yale Paediatric Anxiety Scale (mYPAS) before and during each intervention. Data are presented as mean diff. during the intervention compared with before the intervention (95% CI). Local ethical committee approval: 1-10-72-168-21.
Results: VR-Game and VR-Video had the most pronounced effect on PPT and anxiety level:
VR-Game mean PPT diff.: 136 kPa (112-161), p < 0.0001; mean mYPAS diff.: 6.6 (5.1-8.2), p < 0.0001
VR-Video mean PPT diff.: 122 kPa (91-153), p < 0.0001; mean mYPAS diff.: 5.7 (4.3-7.2), p < 0.0001
The non-immersive Control-Video showed a significant increase in PPT, but no difference in anxiety level. The Control showed no statistically significant difference in PPT and mYPAS.
Conclusions: The use of VR was feasible and had significant positive effects on pain threshold and anxiety level of 6-14 year-old children. Interactive VR-gaming and immersive VR-video had the most pronounced effect. This study provides promising perspectives for the modulation of pain perception and anxiety utilizing VR.
Basic Science
OP-008
An ovine study of retrograde femoral nail removal with and without fat grafting across the open distal femoral physis
Kouami Amakoutou1, Alex Benedick1, Derrick M. Knapik2, Lewis Zirkle3, James M. Anderson4, Raymond Liu1
1Pediatric Orthopaedic Surgery, Rainbow Babies and Children’s Hospital, Case Western Reserve University, Cleveland, USA, 2Department of Orthopaedic Surgery, Washington University Sports Medicine, Saint Louis, USA, 3SIGN Fracture Care, Richland, USA, 5Department of Pathology, Case Western Reserve University, Cleveland, USA
Introduction and Objective: Previous animal data has demonstrated that up to 7% of the distal femoral physis can be violated using a rigid nail without causing subsequent growth inhibition or arrest. The purpose of this investigation was to evaluate the behavior of the distal femoral growth plate following retrograde femoral nail removal with and without placement of fat graft in a sheep model.
Materials and Methods: Retrograde femoral nails were placed in eight immature sheep. After two months, the implants were removed at 8 weeks, and the residual defects were either left open (n = 4 specimens) or filled with autologous fat graft (n = 4 specimens). Four sheep were then allowed to grow for three additional months and four sheep were allowed to grow for five additional months. At sacrifice differences in femoral length between surgical versus contralateral control femurs were measured and the physis was studied histologically.
Results: When compared to the contralateral control limb, surgical limbs measured a mean of 4 ± 1.3 mm (range, 2.7-5.6 mm) shorter in sheep sacrificed at three months, compared to a mean of 1 ± 0.3 mm (range, 0.4-1.2 mm) shorter in sheep sacrificed at five months (p = 0.004). No significant difference in mean shortening was appreciated in limbs without fat grafting (2.4 ± 1.5 mm; range, 1.1-4.3 mm), versus limb with fat grafting (2.5 ± 2.3 mm; range, 0.4-5.6 mm) (p = 0.94). Histological analysis in seven sheep demonstrated trabecular bone spanning the growth plate in 86% (n = 6/7) of specimens.
Conclusions: Mean femur length discrepancy between surgical and control limbs was significantly shorter in sheep sacrificed at 5 months versus 3 months following retrograde implant removal, suggesting that the growth inhibition that occurred following nail removal improved when the sheep were given additional time to grow. Fat grafting did not confer any benefit.
Best of Lower Limb Deformity
OP-009
The long-term effect of femoral leg lengthening on muscle strength - a 10 year follow-up
Bernhard Speth1, Corina Nüesch2, Petros Ismailidis2, Marc Schmid3, Andreas Krieg1
1Pediatric Orthopedic Department, University Children’s Hospital Basel UKBB, Basel, Switzerland, 2Functional Biomechanics Group, University of Basel, Basel, Switzerland, 3University of Basel, Basel, Switzerland
Introduction and Objective: Leg lengthening by callus distraction results in loss of muscle strength. In a previous study we showed that knee extensor muscle strength was still decreased 2 years after surgery. We wondered if this was a short-term effect or if this difference in muscle strength would be permanent.
Materials and Methods: Thirty patients with a median leg length discrepancy of 3.0 cm underwent femoral lengthening with a motorized intramedullary device. Maximum isokinetic concentric torque of the extensors and flexors of the knee was measured before surgery (t1) and 2 years (t2) and 10 years (t3) after surgery. For the long-term analysis, we included all patients with a complete data set and a minimum follow-up of 10 years (n = 9). We examined the differences between preoperative and postoperative maximal isokinetic torques to a control of 10 healthy subjects.
Results: Before surgery, the median maximal isokinetic torque of the extensor group was 16% higher in the normal leg than in the shorter leg. After leg lengthening, the difference between the normal and lengthened leg increased to 17.5% at 2-year follow-up and to 25.6% at 10-year follow-up. In contrast, no change was observed in the knee flexor group and there was no significant loss of maximal isokinetic torque in the lengthened leg (t1 = 2.4%; t2 = 5.7%, t3 = 1%). In the control group, the comparison between the dominant and non-dominant leg showed a difference in knee extension torque of 2.9% and in knee flexion torque of 1.7% in favor of the dominant leg.
Conclusions: The muscle strength of the knee extensors after femoral lengthening does not recover in the long run. We suspect that distraction of the muscle has a higher effect on the muscle properties then than previously thought.
Best of Lower Limb Deformity
OP-010
The Precice plate: An initial experience
Claire Shannon1,2, Aaron Huser1, Dror Paley1,2
1The Paley Orthopedic & Spine Institute, West Palm Beach, USA, 2Paley European Institute, Warszawa, Poland
Introduction and Objective: The introduction of the Precice Plate has expanded the indications for internal limb lengthening in pediatric patients. This study aims to report the preliminary results of the Precice Plate for lower limb lengthening in patients with congenital limb deficiencies and syndromic short stature.
Materials and Methods: A retrospective study was performed including all patients who underwent limb lengthening using the Precice Plate (Nuvasive Specialized Orthopedics, CA) at a single center by two surgeons. Patients were indicated for plate lengthening if the bone to be lengthened was too small in length or diameter for an intramedullary lengthening nail, or if the canal could not be accessed due to open physes.
Results: 20 Precice plates were inserted into 18 patients between September 2020 and January 2021. There were 8 females and 10 males and median age at surgery was 6 years 6 months (2y1m - 21y). Eight femurs, nine tibias and three fibulas were lengthened. Fifteen patients had additional procedures at the time of Precice plate insertion. 17 of 18 patients completed their lengthening to the preoperative goal. One patient, due to deep infection, had the Precice plate removed and an external fixator applied to complete the lengthening. 12 of 18 patients (67%) had a complication during lengthening, with seven requiring an unplanned surgery to resolve the problem. 16 of 18 patients have healed and 11 plates have been removed. Corrosion was seen on one plate. Bending was noted in 10 plates (6 tibias and 4 femurs), and 3 patients required additional treatment as a result of this.
Conclusions: This is an early experience with the Precice Plate. The device allowed 17/18 patients to reach their lengthening goal without the need for external fixation. Although there was a high complication rate, the patients selected were challenging for lengthening at baseline.
Best of Lower Limb Deformity
OP-011
How balance changes during growth in pediatric patients: The role of age and patient anthropometry
Luca Rigamonti1,2, Marco Turati2, Massimiliano Piatti3, Diego Gaddi3, Carlo Alberto Augusti4, Andrea Riganti5, Marta Gandolla6, Giovanni Zatti2,3, Aaron Krych1, Todd Milbrandt, MD1, Marco Bigoni2,3
1Orthopaedic Surgery, Mayo Clinic, Rochester, USA, 2Ortopedia e Traumatologia, University of Milano-Bicocca, Milan, Italy, 3Orthopaedic Surgery, San Gerardo Hospital, Monza, Italy, 4Shoulder and Elbow, Ospedale Cervesi, Cattolica, Italy, 5Department of Economics, University of Milano Statale, Milan, Italy, 6Department of Mechanics, Politecnico of Milano, Milan, Italy
Introduction and Objective: The number of pediatric injuries during sports activities has significantly increased during the last decades. It’s postulated that good balance is a crucial factor to prevent sports injuries. Balance can be assessed via a stabilometry board. The goals of this study were to characterize the balance of pediatric patients, and analyze which factors influence the ability to balance. Our hypothesis was that balance is affected by growth.
Materials and Methods: Soccer players between the ages of 4 and 12 were evaluated. Morphometric parameters were collected. The KTK (Koerperkoordination-Test-fuer-Kinder) test measured coordination, CSAPPA (Children’s-Self-Perception-of-Adequacy-in-and-Predilection-for-Physical-Activity) questionnaire evaluated the level of daily physical activity. Balance was assessed reporting sway path, sway area and sway velocity by a stabilometry board (Balance, Vertigomed, Italy) in 4 different conditions: baseline, without visual (blinded), somatosensory (soft-pad on the board), vestibular input (bending back the head). Coordination and physical activity were evaluated in relation to age with linear regression. Multiple linear regression identified which factors influenced balance.
Results: 113 male soccer players were enrolled (7.9 ± 1.8 years of age). Age was positively correlated with both KTK (p < .01; slope = 20.3; R2 = 0.6), and CSAPPA (p < .01; slope = 2.4; R2 = 0.2). The correlation between age and balance was non-linear, increased until 9 years old and then presented a decrease between 9 and 12 years old. The depletion of somatosensory system showed the higher impairment of balance control compare to the other conditions (p < .01). Multiple linear regression showed that age (p < .01) and weight (p = 0.02) were significant predictors of balance, with weight gain associated with decreased balance ability.
Conclusions: Skeletally immature patients undergo several balance changes as they grow, age and weight (expression of subject growth) predict how balance ability changes in children. It appears that sensory and proprioceptive systems take time to recover good postural control during periods of rapid growth.
Best of Lower Limb Deformity
OP-012
The utility of the modified fels knee skeletal maturity system in limb length prediction
Ryan Furdock1, Elizabeth Cho2, Alex Benedick1, Jiao Yu3, Abdus Sattar3, Raymond Liu1
1Rainbow Babies & Children’s Hospital at Case Western Reserve University, Cleveland, USA, 2Loyola University Medical Center, Chicago, USA, 3Case Western Reserve University, Cleveland, USA
Introduction and Objective: Predicting ultimate lower extremity length is important when treating lower limb discrepancy (LLD) and congenital limb deficiency. Using skeletal age is typically favored over chronological age. The Modified Fels knee skeletal maturity system estimates skeletal age via imaging that is already available in LLD patients, avoiding the need for a separate left-hand radiograph. We evaluated the utility of the Modified Fels knee skeletal maturity system in ultimate limb length prediction of a modern adolescent clinical population.
Materials and Methods: The medical records of all patients treated at our institution over a 20-year period with unilateral lower extremity pathology and available lower extremity imaging before and after reaching skeletal maturity were reviewed. Skeletal maturity was defined radiographically by closed physes. The femoral, tibial, and lower extremity length was measured in all radiographs. The Modified Fels knee skeletal maturity system was applied to all radiographs obtained prior to maturity to estimate skeletal age. The accuracy of three widely utilized lower extremity length prediction systems was compared when using skeletal age versus chronological age inputs.
Results: 245 radiographs (109 prior to maturity) from 43 patients were eligible for inclusion. On cross-sectional analysis, linear mixed effects modeling using skeletal ages was uniformly associated with higher (improved) R2 values than chronological age-based models (R2 = 0.83-0.91 for skeletal age vs 0.79-0.86 for chronological age). On longitudinal analysis, skeletal age models had lower Akaike information criterion (AIC) values than chronological age models in all cases, similarly indicating superior performance.
Conclusions: In treatment of LLD, the Modified Fels knee skeletal maturity system can be readily applied to available imaging to improve the prediction of ultimate femoral, tibial, and lower extremity length. This skeletal maturity system may be useful in estimation of ultimate limb length discrepancy and determination of appropriate timing of epiphysiodesis.
Best of Lower Limb Deformity
OP-013
Congenital pseudarthrosis of the tibia: Rate and time to bone union following contralateral vascularized tibial periosteal graft transplantation in 29 cases
Francisco Soldado1, Paula Diaz-Gallardo2, Jorge Giménez Knorr3
1iPULMi (International Pediatric Upper Limb and Microsurgery Institute), POS, Barcelona, Spain, 2Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 3iiTOP, POS, Barcelona, Spain
Introduction and Objective: Congenital pseudarthrosis of the tibia (CPT) is one of the most challenging orthopedic disorders, with half of these children ultimately requiring amputation. The use of vascularized periosteal flaps has been recently reported as a powerful tool to obtain bone union. We report on bone union capacity using a contralateral vascularized tibial periosteal graft transplant for CPT.
Materials and Methods: Retrospective short-term study of twenty-nine children (18 male, 15 right-sided) of mean age 45 months (range 11 to 144), operated upon after October 2014. Charts only were evaluated through the first three months after bone union was achieved. Nonunion site was debrided, and the periosteum of the involved limb was excised. A vascularized tibial periosteal flap with a monitoring skin island and based on the anterior tibial vessels, was obtained from the contralateral tibia to promote pseudarthrosis healing. Most cases were stabilized with an LCP plate. The rate of and time to bone union were analyzed.
Results: The flap survived and bone union was obtained in all cases, through a periosteal callus, between three and six weeks after surgery (mean = 5.1 weeks). None of the children exhibited any evidence of union failure three months after resuming unprotected weight bearing.
Conclusions: Our novel technique produced a consistent, rapid capacity for CPT union, superior to previously-reported techniques. However, it cannot be recommended as a standard method of treatment until consistent, long-term, refracture-free follow-up is documented.
Best of Lower Limb Deformity
OP-014
Congenital posteromedial bowing of the tibia: Comparison of early and late lengthening
1Centre for Ilizarov Techniques, Chaudhary Hospital, Akola, India, 2Holy Family Hospital, India, 3Sancheti Institute for Orthopaedics and Rehabilitation, India
Introduction and Objective: Congenital posteromedial bowing of tibia (CPMBT), is a rare anomaly, with limited literature on lengthening. Our series compares the duration and complications of lengthening in younger vs. older children to determine early lengthening safety and benefits.
Materials and Methods: We studied 28 tibial lengthenings in 23 patients, divided into two equal groups of 14 segments: group-A ≤ five years (preschool) and Group-B > five years. All were lengthened with circular external fixators, of which three were lengthened over a nail. We measured preoperative (bo) and postoperative (po) sagittal, coronal, and oblique plane deformities, initial limb length discrepancy (LLD), percentage LLD (% LLD), amount of lengthening (AmtL), percentage lengthening (%L), external fixator duration (EFD) and external fixator index (EFI). Complications were graded by Lascombes’ criteria, results by ASAMI Bone score.
Results: The mean age was 8.8 ± 7.1 years; mean follow-up was 7.9 years. Group-A had significantly greater bo-sagittal, coronal, and oblique plane deformities. LLD (3.4 cm in group-A vs. 4.1 cm in group-B) was similar in both. Expected LLD at maturity (LLDM) using the multiplier method was greater than previously reported (group-A: 4.4 - 9.5 cm; group-B: 2.5 - 9.7 cm). Though AmtL (3.5 cm and 4.1 cm) was similar in both, %L was 24% in group-A and 15.7% in group-B (p = 0.002). EFD (116.6 days) and EFI (33.7 days/cm) were lesser in group-A compared to group-B (200.3 days, p = 0.001; 50.2 days/cm, p = 0.01). Lascombes’ triple contract was fulfilled in 11/14 lengthenings in group-A vs. 3/14 in group-B. ASAMI bone score was good and excellent in both groups (p = 0.44).
Conclusions: In the possibly largest series of lengthening in CPMBT reported so far, we found younger children presenting with large deformities and large projected length discrepancies could be safely lengthened with significantly lesser external fixator duration and complications than in older children.
Developmental Dysplasia of the Hip
OP-015
The frequency of formation of acetabular retroversion after reorienting pelvic osteotomies in children with hip dysplasia
Pavel Bortulev1
1Hip surgery Clinic, H.Turner National Medical Research Center for children’s Orthopedics and Trauma Surgery, Saint-Petersburg,Pushkin, Russian Federation
Introduction: One of the reasons for the development of the “pincer” type of femoroacetabular impingement are various pelvic osteotomies, which are widely used in the treatment of children with hip dysplasia.
Objective: To evaluate the frequency of acetabular retroversion after reorienting ilio -pubic, ilio-sciatic, and triple pelvic osteotomies in children over 7 years of age with hip dysplasia Crowe I-II.
Materials and Methods: The retrospective study is based on the results of radiometry of 60 patients (69 hip joints) at an average age of 11.6 ± 2.9 years with hip dysplasia of the Crowe I-II type, who received surgical treatment in the period from 2014 to 2016. The patients were divided into three groups of 20 patients each, depending on the option of performing a reorienting pelvic osteotomy. In addition to standard radiometry of the hip joints, the following indicators were evaluated: “cross-over”, “posterior wall”, “ischial spine” sings and acetabular retroversion index.
Results: There were no significant differences in the radiometric parameters of the spatial orientation of the acetabulum in patients of groups I and II (p > 0.05), with the exception of the degree of bone coverage, the values of which in patients in group II significantly (p < 0.05) exceeded those in group I. Retroversion of the acetabulum was observed in more than half of the patients in group I and in almost all patients in group II. In group III patients, acetabular retroversion was observed in only 3 patients.
Conclusions: Performing a double (ilio-pubic and ilio - sciatic) pelvic osteotomy in the vast majority of cases leads to the formation of hypercorrection of the acetabular fragment and its retroversion in comparison with a triple pelvic osteotomy. In the treatment of children with dysplastic hip instability over the age of 7 years, the operation of choice is a triple pelvic osteotomy.
Developmental Dysplasia of the Hip
OP-016
Outcomes following the management of infant immature hips in a selective screening pathway
Belal Darwich1, Ripak Purbe1, Ben Marson2, Prithviraj Hallikeri3, Kathryn Price4
1Nottingham University Hospitals NHS Trust Queen’s Medical Centre Campus, Trust Grade Doctor, Nottingham, United Kingdom, 2University of Nottingham, NIHR Doctoral Fellow, Nottingham, United Kingdom, 3Nottingham Children’s’ Hospital, SpR Trauma and Orthopaedics, Nottingham, United Kingdom, 4Nottingham University Hospitals NHS Trust Queen’s Medical Centre Campus, Paediatrics Orthopaedics, Nottingham, United Kingdom
Introduction and Objective: In the UK children with hip risk factors or a positive examination are referred for ultrasound assessment. The ideal management of the immature hips is currently unclear with evolving national guidelines. The aim of this study is to evaluate the outcomes for children with immature hips managed in our selective screening pathway.
Materials and Methods: All children reviewed in the infant hip clinic between 1/1/2016-1/1/2021 were prospectively registered on our institutional database. Children who attended before 3 months of age with a radiographically immature (alpha angle 50-59°) were included. Children with co-existing dysplastic hips were excluded. Parents of children with immature hips were given standardised hip care advice including usage of double nappies and avoidance of swaddling. Follow up was based on clinical and radiographic findings.
Results: 395 children were identified with immature hips. The mean age at presentation was 30.3 days and 96 (24.3%) were male. 372 hips (94.1%) resolved with no further intervention with a mean of 2.4 follow up scans before a radiographically normal hip was demonstrated. Hip dysplasia requiring treatment in Pavlik harness was subsequently diagnosed in 23 (5.8%) children (including 3 Graf 3 and 1 Graf 4 hips). All were treated in Pavlik with no children requiting surgical reduction. Of those requiring harness treatment, 15 children (65.2%) were referred as clinically normal or with a ‘clicky’ hip.
Conclusions: Progression of immature hips is uncommon with 94.1% resolving with conservative measures. We have found excellent resolution of immaturity without using Pavlik harness. We have not been able to identify risk factors to predict progression, so would advocate a second scan for all children with immature hips. In our pathway, the value of neonatal clinical examination remains variable, with significant false positives and negatives that is mitigated with a low threshold for ultrasound scanning.
Developmental Dysplasia of the Hip
OP-017
Infants with clinical instability of hip should be seen by 2 weeks of age
Hean Wu Kang1, Aidan Cosgrove1
1Trauma & Orthopaedics, Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland
Introduction and Objective: Our region provides selective surveillance for developmental dysplasia of hip (DDH). Our policy is that neonates referred with clinical abnormality should have a hip ultrasound scan by 2 weeks of age and those with risk factors have a scan by 6 weeks. In 2021, England changed its policy to recommend neonates with clinical abnormality have ultrasound scan between 4-6 weeks of age. This was due to a belief that a proportion of these hips will locate and stabilize spontaneously. As we have not always met our targets due to logistical constraints, we opportunistically assessed if infants experiencing delay in treatment beyond 2 weeks of age had a higher operative rate.
Materials and Methods: We reviewed all 906 infants treated from 2017-2019 birth cohort. We identified those referred with abnormal findings before their 6-week assessment with an ultrasonic diagnosis of hip dislocation, subluxation or instability. Infants with dysplasia in isolation were excluded. Initial treatment was by Pavlik harness. If the hip failed to locate by 2 weeks splintage was abandoned. We compared the operative rate of infants for whom treatment was initiated ≤2 weeks of age and > 2 weeks to 8 weeks of age.
Results: Both groups had similar demographics, two infants had dislocations of knees in the early treatment group. 74 infants (92 hips) that were treated ≤2 weeks of age had an operation rate of 4.3%. 39 infants (46 hips) treated > 2 weeks of age had operation rate of 19.6%. One of whom developed avascular necrosis (AVN). There was no AVN in children exclusively treated with Pavlik treatment.
Conclusions: Infants treated for DDH > 2 weeks of age experience a significantly higher operation rate. Given the minimal complication rate with a harness, infants with clinically suspect DDH should be diagnosed and treated as early as possible.
Developmental Dysplasia of the Hip
OP-018
Children’s Hip Predictive Score (CHiP): A triage tool for predicting dislocations in children referred with hip dysplasia
Evelyn Murphy1, Catherine Howell1, Olga Gallagher1, Paula Kelly1, Patrick O’Kelly2, Jacques Noel1, David Moore1, Patrick O’Toole1, Jim Kennedy1
1Children’s Health Ireland (CHI) at Crumlin, Dublin, Ireland, 2Beaumont Hospital, Dublin, Ireland
Introduction and Objective: A fundamental tenant of treating hip dysplasia (HD) is to identify patients with dislocated hips early so as to avoid the long-term sequelae of late diagnosis. The aim of this study was to develop a broadly applicable statistical model to predict patients with dislocated hips based upon the clinical history and examination findings of the referring practitioner
Materials and Methods: All patient referrals (n = 934) over a three year period for suspected HD in a tertiary paediatric centre were evaluated. Defined parameters with respect to history and clinical examination were evaluated. A multivariate logistic regression model was derived, and adjusted odds ratios (OR) with 95% confidence interval was calculated for significant predictors. An illustrative nomogram was developed with a predictive score, Children’s Hip Predictive (CHiP) score, for the presence of a dislocated hip on initial referral.
Results: There were 97 dislocated hips in 85 patients. The predictive model includes age, gender, family history, breech, gait concerns, decreased abduction, leg length discrepancy and medical/neurological syndrome. A CHiP score of > 15 gives a risk probability of dislocation at.575 where as a score of < 5 gave a risk of dislocation of 0.047. The area under the receiver operating curve (AUROC) for the model was calculated to be 0.761.
Conclusions: The CHiP score strongly predicts risk of dislocations in HD referrals based on clinical history and examination findings. A score > 15 has an increased OR of 27.3 for having a risk of dislocation. It is hoped that this tool could be utilized to optimize resource allocation and will be of particular benefit in less well resourced health care systems
Developmental Dysplasia of the Hip
OP-019
Outcomes of treatment for developmental dislocation of the hip when the Pavlik method has failed
Carlos Pargas1, Karim Masrouha1, Cordelia Carter1, Pablo Castaneda1
1Orthopedic Surgery, New York University, New York, USA
Introduction and Objective: The Pavlik method for the treatment of developmental dislocation of the hip has proven successful, making it one of the most popular treatments in the world, however there is a paucity in literature on the optimal treatment of hips that fail the Pavlik method. This study aims to determine the outcome of hips that have failed to achieve reduction with the Pavlik method.
Materials and Methods: This was a retrospective study of 144 patients with a unilateral developmental dislocation of the hip treated with the Pavlik method with at least 36 months of follow up. After excluding patients with neuromuscular conditions, teratologic dislocations, and arthrogryposis, we identified 23 patients where the hip was not reduced with the Pavlik method. These subsequently went on to have either closed reduction (CR), 7 patients, open reduction (OR), 3 patients, or open reduction and pelvic osteotomy (OR+PO), 13 patients. We identified the rate of proximal femoral growth disturbance (PFGD), formerly known as avascular necrosis and the rate of requiring a reintervention.
Results: The mean age of the patients who did not achieve reduction with the Pavlik method was 4.03 months compared to 1.08 for those in which it did (p < 0.05). Of the 7 patients who went on to closed reduction, 71% presented a PFGD, and 85% required a reintervention. Of the 3 of the patients who went on to open reduction, all of them presented PFGD and 66% required a reintervention. Of the 13 patients went on to OR+PO, 46% had PFGD and no hip in this group required a reintervention.
Conclusions: Patients with developmental dislocation of the hip who fail to achieve reduction with the Pavlik method had a high incidence of PFGD and need for reoperation after a CR or OR especially when compared to OR+PO.
Developmental Dysplasia of the Hip
OP-020
Bilaterality: What influence on the prognosis of developmental hip dysplasia?
Cristina Alves1, André Carvalho1, Ines Balacó1, Pedro Sá Cardoso1, João CABRAL1, Oliana Madeira Tarquini1, Marcos Carvalho1, Tah Ling1
1Hospital Pediátrico, Department of Pediatric Orthopaedics, CHUC, EPE, Coimbra, Portugal
Introduction and Objective: Developmental Dysplasia of the Hip (DDH) has a variable incidence, affecting 1.7-188:1000 newborns, depending on diagnostic criteria and ethno-geographic factors. Early diagnosis contributes to a better prognosis, but some patients need surgery. Bilateral DDH is thought to have a worse prognosis. The objective of this study is to compare, in patients aged < 2 years, who underwent attempted surgical treatment by means of closed reduction, adductor longus ± psoas tenotomy and spica cast, the results obtained in terms of avascular necrosis (AVN) and redislocation.
Materials and Methods: Retrospective cohort study, including patients with DDH, age < 2 years, treated in 2011-2016, minimum 5 years follow-up. Included patients undergoing attempted closed hip reduction, adductor longus ± psoas tenotomy and spica cast. Excluded syndromic/neuromuscular patients. Two groups compared: DDH with bilateral hip dislocation versus DDH with unilateral dislocation. Radiographic results, need for open reduction, avascular necrosis and redislocation rates were evaluated. For statistical analysis, we used Student’s t test, chi-square and Fisher’s test. Statistically significant differences were considered for p < 0.05.
Results: We included 53 patients, 91.8% female, with 61 hips undergoing treatment. Bilateral dislocation affected 9 (17%) patients. IHDI classification: 40% hips IHDI-I, 53.3% IHDI-III, 6.7% IHDI-IV. Age at surgery was 7.91 ± 3.49 months in unilateral group and 5.94 ± 1.55 months in bilateral group (p = 0.026). Need for open reduction was significantly different (p = 0.039) between unilateral group (4.7% hips needed open reduction) and bilateral group (22.2% hips needed open reduction). Overall AVN rate was 16.7%. AVN was 19% in unilateral dislocation group and 11.1% in bilateral (p = 0.450). Overall redislocation rate was 8.3%. Median time to redislocation after treatment was 8 (6-12) months. Redislocation was 7.1% in unilateral group and 11.1% in bilateral (p = 0.610).
Conclusions: DDH patients with bilateral hip dislocation are more likely to require open reduction, but they do not appear to have worse outcomes for AVN or hip redislocation.
Developmental Dysplasia of the Hip
OP-021
The clinical significance of infolded limbus on post-reduction arthrogram in developmental dysplasia of the hip
William Morris1 2, Sai Chilakapati2, Sean Hinds1, John Anthony Herring1 2, Harry K. W. Kim1 2
1Scottish Rite for Children, Orthopedics, Dallas, USA, 2Orthopedics, University of Texas, Southwestern Medical Center, Dallas, USA
Introduction and Objective: The purpose of this study was to investigate whether presence of an infolded limbus on hip arthrogram at index closed reduction was associated with increased residual dysplasia or secondary surgery.
Materials and Methods: We retrospectively reviewed all patients who underwent closed reduction for Developmental Dysplasia of the Hip (DDH) with minimum 2-year follow-up between 1980-2016. Arthrograms performed at time of closed reduction were separately reviewed by three fellowship-trained paediatric orthopaedic surgeons to evaluate for infolded limbus. The primary radiographic outcome was acetabular indices at two- and four-years post-reduction. We also assessed the presence of avascular necrosis and rate of secondary reconstructive surgery for residual dysplasia.
Results: 182 hips in 165 patients underwent closed reduction at a mean age of 9.8 ± 4.5 months and were followed a mean of 9.0 ± 4.9 years. An infolded limbus was identified in 20.3% (37/182) hips with substantial agreement among the three graders (Fleiss’s Kappa = 0.75). The frequency of labral infolding increased with the severity of dislocation (8.8%% of IHDI II, 26.7% IHDI III, and 25.0% of IHDI IV hips; p = 0.03). Hips with infolded limbus were older at reduction (12.4 ± 5.3 vs 9.2 ± 5.8 months, p = 0.001). The mean acetabular index was slightly higher in hips with infolded limbus than hips without at 2-years post-reduction but the difference was statistically significant (34.8 ± 4.8 vs 32.6 ± 5.8 degrees, respectively; p = 0.04). No significant difference was seen at 4-years post-reduction (27.2 ± 7.4 vs 25.4 ± 6.5 degrees, p = 0.24). There was no difference between hips with labral infolding and those without in rate of secondary surgery (35% vs 30%, respectively; p = 0.52) or avascular necrosis (p = 0.74).
Conclusions: An infolded limbus was more common in older patients with more severe dislocations. However, it is not associated with clinically significant increased residual dysplasia or secondary surgery and may have limited utility in decision-making during closed reduction.
Developmental Dysplasia of the Hip
OP-022
Brace treatment does not improve acetabular coverage or reduce the rate of secondary surgery following closed reduction of developmental dysplasia of the hip
Arnav Kak1, William Morris1,2, Laura Mayfield2, Harry K.W. Kim1,2
1UT Southwestern Medical Center, Dallas, USA, 2Scottish Rite for Children, Dallas, USA
Introduction and Objective: Abduction bracing is commonly used to treat DDH following closed reduction (CR) and spica casting. There is little evidence to support or refute this practice that imposes daily restriction and burden on patients and parents. The purpose of this study was to determine the efficacy of abduction bracing after CR in improving the acetabular index (AI) and reducing secondary surgery for residual hip dysplasia.
Materials and Methods: This is a retrospective review of patients treated with CR at a tertiary referral center. We obtained clinical data (age at reduction, cast duration, bracing regimen), severity of dislocation using IHDI classification, and acetabular index (AI) measurements immediately upon cast removal and from 2- and 4-year follow-up X-rays. Uni-/multivariate analyses were performed.
Results: 258 hips underwent CR and 70.5% (182/258) were treated with abduction bracing. There was no difference between those treated with or without bracing with regards to sex (p = 0.92), age at reduction (p = 0.77), severity of dislocation (p = 0.21), or immediate post-casting AI (p = 0.21). The bracing cohort was casted longer than the non-bracing cohort (14.0±3.4 vs 12.8±4.8 weeks, p = 0.03). There was no difference in hips treated with or without bracing with regards to AI at 2 years (32.1±5.7 vs 30.5±6.2, p = 0.13) or 4 years (25.8±5.8 vs 25.6±6.9, p = 0.96). When categorized by full-time, part-time, or no bracing, there were similarly no differences in AI at 2 or 4 years (p = 0.28 and 0.45). Multivariate analysis revealed only IHDI grade predicted AI at 2 years post-CR (p = 0.01). There was no difference in the rate of secondary surgery for residual dysplasia between hips treated with or without bracing (35% vs 38%, p = 0.69).
Conclusions: Abduction bracing post-CR is not associated with decreased residual dysplasia at 2-/4-years post-reduction or with decreased secondary surgery. These results indicate that there may be no clinical value in post-reduction bracing.
Hip 1
OP-023
Treatment of hip instability in children with down syndrome: Keys to managing a challenging problem
Jessica Hughes1, James Bomar1, Dennis Wenger1, Vidyadhar Upasani1
1Rady Children’s Hospital - San Diego, San Diego, USA
Introduction and Objective: Management of hip instability in children with Down Syndrome is a challenging task to undertake for even the most experienced surgeons. The aim of this study is to evaluate the clinical and radiographic outcomes of children with Down syndrome and hip instability who underwent surgical reconstruction with femoral and/or acetabular procedures.
Materials and Methods: We performed a retrospective review of all children with Down Syndrome less than age 18 years, who underwent surgical intervention to address hip instability between 2003 and 2017. Data was recorded detailing the patient’s demographics, preoperative and postoperative functional status and surgical details. Preoperative and postoperative radiographic analysis was performed as well as 3D CT scan evaluation, when available. All major and minor complications were recorded and classified using the Severin radiographic classification and the Clavien-Dindo-Sink clinical classification.
Results: We studied 28 hips in 19 children that were followed for an average of 4.4 years post-surgical intervention for hip instability. The majority of patients improved in all radiographic parameters. A total of 14 hips (50%) had complications and 9 hips (32%) required a secondary surgery. Of those complications, 2 hips (7%) developed AVN and 4 hips (14%) developed recurrent instability after the index procedure. Two of these hips had a subsequent anteverting periacetabular osteotomy that produced a stable hip at final follow up.
Conclusions: Surgical management of hip instability in children with Down Syndrome remains challenging. The treating surgeon must have a thorough understanding of the pathoanatomy and design the surgical treatment to meet all of the underlying sources of instability. Combined femoral and acetabular osteotomies plus capsulorrhaphy are often required in along with post-operative hip spica immobilization. Although complication and revision surgery rates are high, hip stability and good functional outcomes can be achieved.
Hip 1
OP-024
The first North American hip surveillance program: Enrollment after five years
Stacey Miller1,2, Jennifer Farr1, Kit Johnson3, Kishore Mulpuri1,4
1Department of Orthopaedic Surgery, BC Children’s Hospital, Vancouver, Canada, 2Department of Physical Therapy, University of British Columbia, Vancouver, Canada, 3Child Health BC, Vancouver, Canada, 4Department of Orthopaedics, University of British Columbia, Vancouver, Canada
Introduction and Objective: The Child Health British Columbia (BC) Hip Surveillance Program for Children with Cerebral Palsy is the first province/state wide hip surveillance program in North America. This paper reports the first 5 years of enrollment.
Materials and Methods: All children with cerebral palsy living in BC born in the years 2000 to present are eligible for enrollment in the program. Data for all children enrolled up until August 10, 2021, five years from full provincial enrollment, were reviewed.
Results: In total, 1183 children (56% male) have been enrolled (Gross Motor Function Classification Score, GMFCS level I: 29%, II: 24%, lII: 11% IV: 22%, Level V: 20%, unknown 2%). Total enrollment represents 74.5% of expected children born 2010-2019 and 42.9% born 2000-2009 based on population and prevalence data. This represents 59% of expected at GMFCS levels I and II, 75% level III, and 100% levels IV and V for children born 2010-2019. Migration percentage was > 30% in 36% of the cohort and was related to GMFCS. Hip dislocation was present at enrollment in 16 children (mean age 10.0 years, SD 4.4), the youngest being 2.1 years. In 9 of these children, reconstructive surgery was not possible and/or salvage surgery was completed (mean age 12.4, SD 2.2). All children under 10 years underwent reconstructive surgery except one who was too unwell. Eleven children progressed to dislocation (mean age 7.7 years, SD 4.6) ; 2 required salvage surgery (mean age 15.0 years).
Conclusions: Incidence of hip displacement are similar to other population based programs. The program has been successful at identifying children at highest risk for hip displacement and referring to orthopaedics to prevent salvage surgery. This program, like others, has demonstrated dramatic reduction in hip dislocations. Salvage surgery was avoided when dislocations were identified and surgery offered before age 10.
Hip 1
OP-025
Acetabular retroversion in juveniles - mostly caused by a reduced lumbo-pelvic angulation
1Klinik für Kinderchirurgie, Sektion Kinder- und Neuroorthopädie, Klinikum Dritter Orden, München, Germany, 2Zentrum für Radiologie und Nuklearmedizin, Kliniken Dritter Orden, München, Germany
Introduction and Objective: Longterm groin pain, caused by an acetabular retroversion is a common problem in juveniles. Up to now acetabular retroversion is mostly considered to be an exclusively intrapelvine deformity. On the other hand studies of the lumbo-pelvic alignment showed that a flatback-pelvic retroversion type may go along with an acetabular retroversion. Objective was to differentiate whether an acetabular retroversion is an exclusively acetabular defomity or a consequence of an alignment-induced pelvic retroversion.
Materials and Methods: 36 juvenile patients (72 hips, ♂:♀ = 13:23, ∅ 15,8y) whose acetabular retroversion was confirmed by longterm groin pain and crossover/ischial spine/posterior wall signs additively were evaluated by a faux-profile view and a lumbo-pelvic standing lateral view. Radiological parameters were Pelvic Incidence (PI), Sacral Slope (SS), Pelvic Tilt (PT) and ACE-angle.
Results: 27 Patients (54 hips) showed a flatback-pelvic retroversion typus, defined by a pathologic Pelvic Incidence lower than 44° (min 22,1°/∅ 35,1 ± 4,3°/max 41,1°) followed by a reduced Sacral Slope (min 22,5°/∅ 30,6 ± 5,5°/max 48,2°) and Pelvic Tilt (min 10,8°/∅4,5 ± 6,5°/max 14°). The ACE- angle as a surrogate parameter for acetabular overcovering was enlarged (min 31,1°/∅ 44,1 ± 6,9°/max 57,4°). 9 Patients (18 hips) showed a regular lumbo-pelvic alignment and an exclusively acetabular deformity. Pelvic Incidence was min 41,7°/∅ 48,0 ± 4,7°/max 58,1°, Sacral Slope min 25,8 °/∅ 36,2 ± 5,2°/max 44,5° and Pelvic Tilt min 4,8°/∅ 12,0 ± 3,4°/max 17,5°. The ACE-angle was enlarged (min 35,6°/∅ 46,1 ± 6,4°/max 57,0°).
Conclusions: In our study two-thirds of all acetabular retroversions were due to a pathological lumbo-pelvic alignment. This is characterised by a reduced Pelvic Incidence followed by a flat back and pelvic retroversion. In these patients the indication for surgery has to be decided restrictively. For patients with a high level of suffering innovative methods have to be discussed.
Hip 1
OP-026
Two surgical alternatives for Perthes disease: Intertrochanteric osteotomy vs trochanteric tethering
Peter Stevens1, Olivia Grothaus2
1Orthopedics, University of Utah Hospital, Salt Lake City, USA, 2Orthopedics, University of Utah Hospital, Salt Lake City, USA
Introduction and objective: Varus intertrochanteric osteotomy (ITO) remains the most popular surgical method to provide “containment” of the fragmenting femoral head, due to Perthes disease. We are comparing a series of children treated with ITO to a similar group that underwent less invasive, guided growth (GG) of the greater trochanter ± open adductor tenotomy,
Materials and Methods: This IRB approved, retrospective review compares children with Perthes disease and whole head involvement. One group underwent ITO and the other GG of the greater trochanter. Open tenotomy was included prn. We assessed range of motion and analyzed weight bearing pelvic x-rays pre-operatively and at follow up.
Results: There were 58 patients:18 had (ITO) vs. 40 who underwent (GG). The groups matched with respect to age at diagnosis, gender, BMI percentile, pre-operative exam radiographic parameters. Average length of follow up was 5.06 years. The observed change in the center head-trochanteric distance over time was statistically significant (p < 0.05) with a change of -0.45 cm in GG vs -1.30 cm in ITO patients. No significant differences were detected in medial clear space distance change or Reimer’s index. On follow up exam, 33% of ITO vs 13% of GG patients demonstrated a Trendelenburg gait. 56% of ITO patients had LLD > 0.5cm vs 35% of the GG group. 94% of ITO patients vs 40% of GG required additional surgery. At follow up, 52.5% of GG patients were classified as Stulberg III or greater, compared to 72.2% of the ITO group.
Conclusions: Containment by ITO reflects exclusive focus upon the fragmenting femoral head, without considering the long term sequelae of coxa brevis, including abductor insufficiency, acetabular dysplasia, and LLD. Consequently, the ITO patients had increased trochanteric overgrowth, higher Stulberg classification. GG addresses the insidious femoral neck issues with better outcomes and fewer surgeries, compared to ITO.
Hip 1
OP-027
Publication bias in orthopedics: A study on the reporting of positive outcomes in Legg-Calvé-Perthes disease
Peter Filtes1, Timothy Roberts1, Keenan Sobol1, Pablo Castaneda1
1Orthopaedic Surgery, New York University, Grossman School of Medicine, New York, USA
Introduction and Objective: Legg-Calve-Perthes Disease (LCPD), a syndrome of idiopathic osteonecrosis of the proximal femoral epiphysis, is relatively rare. Despite having few evidence-based approaches, many patients with LCPD are managed surgically. Publication bias is a phenomenon in which positive surgical outcomes are preferentially published. This study aims to conduct a systematic literature review with the hypothesis that publication bias is present for the treatment of LCPD.
Materials and Methods: We conducted a systematic review of all available abstracts associated with manuscripts in English or with English translation between 1993 and 2021, dealing with the treatment of LCPD. Data collection included various study characteristics, surgical vs non-surgical management, treatment modality, mean follow-up time, analysis methods, and clinical recommendations.
Results: Our study included 132 published manuscripts from 1993 to 2021. We found that 117 (89%) of abstracts supported surgical intervention or a combination of surgical and conservative management over strict non-operative treatment (11%). Overall, 111 (84%) of abstracts reported positive results, while only 21 (16%) showed negative results (2%) or no significant difference (14%). This finding is higher than the 74% positive outcome rate found amongst studies for other surgically treated disorders and significantly higher than most scientific literature. Of all the studies, only 5 (4%) recommended against surgical management, while 71 (54%) supported surgery and 56 (42%) offered no recommendation.
Conclusions: The overall publication rate for positive outcome studies regarding LCPD is higher than other surgical disorders. Additionally, most published papers suggest surgical over conservative management as the mainstay of treatment for LCPD despite the lack of support from randomized controlled studies. These findings indicate a positive outcome bias amongst LCPD studies and bias in publishing surgically inclined studies.
Hip 1
OP-028
Effectiveness of triple pelvic osteotomy in patients with Legg-Calve-Perthes disease. Results of minimum 10 years follow up
1Orthopaedics and Traumatology, Hacettepe University,Faculty of Medicine, Turkey, 2Orthopaedics and Traumatology, Acibadem Ankara Hospital, Turkey, 3Orthopaedics and Traumatology, Ministry of Health, University of Health Science, Antalya Research and Education Hospital, Turkey, 4Orthopaedics and Traumatology, Polatli, Duatepe Government Hospital, Turkey
Introduction and Objective: Triple pelvic osteotomy is one of the effective surgical treatments for Legg-Calve-Perthes disease in obtaining a compatible hip joint during skeletal development to achieve normal function and reduce the risk of osteoarthritis, yet its long-term results have not been fully assessed. We aimed to determine the long-term clinical and radiographic outcome of triple pelvic osteotomy for the treatment of Legg-Calve-Perthes disease.
Materials and Methods: We retrospectively reviewed 31 hip with Legg-Calve-Perthes disease in the active stage of the disease who were treated with triple pelvic osteotomy between 2001 to 2007. The criteria for the operation were the patients were being older than six years of age and having Lateral Pillar C hip. There were 24 male and 7 female patients in the study group. The mean age of the patients was 7.7 years. The mean follow up was 12.8 years. All the patients had minimum ten years follow up.
Results: All the hips were evaluated according to the Stulberg classification by one senior (MCA) and one junior (EO) author. According to this evaluation 10 hips had sferic congruency (3 Stulberg 1 and 7 Stulberg 2), 19 hips had asferic congruency (Stulberg 3) and 2 hip had asferic incongruency. None of the hips had osteoarthritis at the time of latest evaluation. Femoral varus osteotomy was done for one hip due to persistent lateral subluxation after triple pelvic osteotomy. Relative femoral neck lengthening was done for three hips via surgical hip dislocation due to femoroacetabular impingement and trochanteric overgrowth. The patients had impingement symptoms and symptoms disappeared after surgical treatment.
Conclusions: Triple pelvic osteotomy can be a preferred method for the patients who had lateral Pillar C type and older than six years of age, and it commonly end up a hip with aspheric congruent appearance.
Hip 2
OP-029
Femoroacetabular impingement in the unpinned contralateral hip in patients with primary unilateral slipped capital femoral epiphysis - preliminary radiographic outcomes
Magdalena Kwiatkowska1, Marcin Kwiatkowski1, Maria Czubak-Wrzosek2, Jaroslav CZUBAK1, Marcin Tyrakowski2
1Department of Orthopedics, Pediatric Orthopedics and Traumatology, Centre of Postgraduate Medical Education, Otwock, Poland, 2Department of Spine Disorders and Orthopaedics, Centre of Postgraduate Medical Education, Otwock, Poland
Introduction and Objective: The study evaluated femoroacetabular impingement (FAI) in the unpinned contralateral hip in patients with unilateral slipped capital femoral epiphysis (SCFE) and verified initial age, posterior sloping angle (PSA) and center-edge angle (CEA) as predictors of FAI in the contralateral hip.
Materials and Methods: 152 patients with unilateral SCFE with a mean index age of 13.2 years (8.2-17.2 years) were enrolled retrospectively into the study. Mean follow-up was 8 years (3-14years). PSA and CEA were measured on initial radiographs of the unaffected hip. Alpha-angle and CEA were measured on radiographs taken at last follow-up in order to identify FAI.
Results: Four groups of patients were distinguished: (1) no FAI (10 patients-17.54%) ; (2) cam-type FAI (41 patients-71.9%) ; (3) pincer-type FAI (3 patients-5.26%) and (4) mixed-type FAI (13 patients-22.8%). The mean PSA was 12.1°, 12°, 16.8°, 11.9° for group 1, 2, 3 and 4, respectively, with no significant difference (p = 0.65). The mean initial CEA for groups 1, 2, 3, and 4 was 34.4°, 35.5°, 42° and 42° respectively, with significant differences between groups 1 vs. 4 (p = 0.034) and 2 vs. 4 (p = 0.009).
Conclusions: 1) Radiographic features of FAI were present in 85.1% of unpinned contralateral hips in patients with unilateral SCFE. 2) 71.9% of unpinned contralateral hips developed CAM deformity. 3) CEA can be used in predicting pincer-type FAI in the contralateral hip in unilateral SCFE. 4) PSA and age revealed negligible value in predicting FAI.
Hip 2
OP-030
Incidence and risk factors of heterotopic ossification in a matched cohort adolescent population undergoing hip arthroscopy
1Harvard Medical School, Boston, USA, 2Orthopaedic Surgery, Division of Sports Medicine, Boston Children’s Hospital, Boston, USA
Introduction and Objective: Heterotopic ossification (HO) is a known complication after hip arthroscopy in adults, positively associated with larger CAM resection, male sex, older age, and obesity, and negatively associated with NSAID use. These characteristics have not been well-documented in adolescents. The objective of this study was to determine the incidence and risk factors for HO development in adolescent patients undergoing hip arthroscopy.
Materials and Methods: Records from a pediatric institution were queried to identify patients aged 21 years or younger who underwent hip arthroscopy between 2008 and 2018. The 27 cases that developed HO were matched 1:4 on age and sex with 107 controls. Bivariate analysis assessed the relationship between demographic/perioperative factors and HO development. Multivariable logistic regression evaluated the role of prophylactic NSAID use (indomethacin 75mg, x3 weeks).
Results: Twenty-seven of 568 (4.8%) hips developed HO within two years of hip arthroscopy. Prophylactic indomethacin (n = 27) was not significantly associated with HO development (n = 8, p = 0.83), after controlling for surgeon and CAM resection - nor were age, sex, and BMI percentile (Table 1). For each degree increase in CAM resection, there was an 8% increase in the odds of HO development (OR = 1.08; 95% CI = 1.02, 1.15; p = 0.01). Of patients who developed HO, a smaller proportion underwent reoperation for HO excision among those who received prophylactic indomethacin (13%; 1/8; p = 0.03) than those who did not (63%; 12/19).
Conclusions: The incidence of HO within two years of hip arthroscopy in this adolescent population was 4.8%. Resection of larger CAM lesions was a risk factor for the development of HO. Although studies in the adult hip arthroscopy population have demonstrated a protective role for NSAIDs in radiographic HO, the effect was less certain in this adolescent sample. Larger studies are important to further evaluate the role of prophylactic NSAIDs and variations in arthroscopy technique.
Cohort demographics separated by development of HO (N = 134).
Preop arthroscopy alpha angle
(degrees,- mean + SD)
65.4
9.19
65.3
8.53
65.5
9.38
0.94
Change in arthroscopy alpha angle
(degrees,- mean + SD)
−20.1
+ 7.79
−16.7
+ 5.55
−20.9
+ 8.05
0.002
Prophvlactic NSAIDs (indomethacin)
27
(20%)
8
(30%)
54
(50%)
0.05
HO, heterotopic ossification; SD, standard deviation.
The number in parentheses represents the number of cases with available data for the given characteristic.
Hip 2
OP-031
Cementless ceramic-on-ceramic total hip replacement in children and adolescents
Stefano Stallone1, Giovanni Trisolino1, Paola Zarantonello1, Stefano Lucchini2, Giovanni Gallone1, Barbara Bordini3, Dante Dallari4, Francesco Traina2
1Pediatric Orthopedics and Traumatology, 2Orthopaedic-Traumatology and Prosthetic Surgery and Revisions of Hip and Knee, 3Medical Technology Laboratory, 4Conservative Orthopedic Surgery and Innovative Technique, IRCCS - Rizzoli Orthopedic Institute, Bologna, Italy
Introduction and Objective: Total hip replacement (THR) is a rare surgical option in children and adolescents with disabling hip diseases. The aim of this study is to report results from a retrospective cohort of patients aged 18 years or less who underwent cementless Ceramic-on-Ceramic (CoC) THR at a single institution, investigating clinical and radiographic outcomes, survival rate and reasons for revision of the implants.
Materials and Methods: we queried the Register of Prosthetic Orthopedic Implants (RIPO) to identify all children and adolescents undergoing THR between 2000 and 2019 at a single Institution. Inclusion criteria were patients undergoing cementless CoC THR, aged less than 18 years at surgery, followed for at least 2 years. Sixty-eight patients (74 hips) matched all the inclusion criteria and were enrolled in the study. We assessed the clinical and radiographic outcomes, the rate of complications, the survival rate and reasons for revision of the implants.
Results: The mean follow-up was 6.6 ± 4.4 years (range 2-20). The most frequent reason for THR was post-traumatic or chemotherapy-induced avascular necrosis (38%). Two THR in two patients (2.7%) required revision. The overall survival rate of the cohort was 97.6% (95% CI: 84.9 - 99.7) at 5 years of follow-up, 94.4% (95% CI: 79.8 - 98.6) at 10 years and 15 years of follow-up; no pre-operative or intra-operative variables were significantly associated to the survivorship (p value < 0.001). The average HOOS was 85 ± 14.3 (range 30.6-100). Overall, 23 patients (48%) reported excellent HOOS scores (> 90 points). Twenty-one patients (43%) were regularly involved into moderate-to-high intensity sport activities (UCLA ≥ 6).
Conclusions: Cementless CoC THR is a successful procedure in children and teenagers, showing high implant survivorship and low rates of complications and failure. A meticulous pre-operative planning and implant selection is mandatory to avoid implant malposition, that is the main reason of failure and revision in these cases.
Hip 2
OP-032
What is the AVN rate of SCFE patients with complete epi-metaphyseal discontinuity treated with the modified Dunn procedure?
Kai Ziebarth1, Thoralf Liebs1, Nadine Kaiser1, Klaus-Arno Siebenrock2, Till Lerch3
1 Department of Pediatric Surgery, 2 Department of Orthopedic Surgery, 3Department of Radiology, Inselspital Bern, Bern, Switzerland
Introduction and Objective: The modified Dunn procedure has the potential to restore the anatomy in hips with slipped capital femoral epiphyses (SCFE). However, there is controversy about the risk for avascular necrosis of the femoral head (AVN). Therefore, we report on 1) AVN rate (2) complications, (3) the cumulative survivorship at follow-up in patients undergoing the modified Dunn procedure for hips with unstable SCFE.
Materials and Methods: We performed a retrospective analysis involving 59 patients (59 hips) treated with a modified Dunn procedure for unstable SCFE between 1999 and 2020. All patients were unstable intraoperatively (complete epi-metaphyseal discontinuity). Mean preoperative age was 13 ± 2 years (range 10-16) and 46% (27 patients) presented with severe slips. Mean preoperative slip angle was 51 ± 16° (20-80). Mean follow-up was 9 ± 5 years (range 1-23). At minimal 1 year-follow-up, all (100%) were available for clinical follow-up. Standardized Questionnaire were available of 38 patients at follow-up. Survivorship (Kaplan-Meier) was calculated using the endpoint AVN.
Results: 1) Four patients (7%) had AVN and had subsequent surgeries. One of them underwent total hip arthroplasty (2%), one patient underwent hip arthrodesis and two patients (3%) underwent intertrochanteric osteotomy and pelvic osteotomy. 2) Three additional patients (5%) had complications that required surgical treatment, two of them underwent revision osteosynthesis (3%) because of screw breakage. One patient underwent open resection of periarticular ossifications and cam resection at 3year follow-up, five patients showed periarticular ossifications without surgical treatment. One patient underwent open cam resection at 10year follow-up. 3) Survivorship was 93% at cumulative 10-year follow-up. At follow-up, mean Merle d’Aubigne and Postel score was 17 ± 1 points (14-18) of the 55 patients without AVN.
Conclusions: Treatment with modified Dunn procedure for unstable SCFE (intraoperatively) resulted in low AVN rate and low complication rate. Patients without AVN had high hip scores at 9 years of follow-up.
Hip 2
OP-033
Is hip dysplasia associated with trochlear dysplasia in skeletally mature patients?
Andrew Fithian1, Ann Richey1, Seth Sherman1, Kevin Shea1, Stephanie Pun1
1Department of Orthopaedic Surgery, Stanford University, Redwood City, USA
Introduction and Objective: Hip dysplasia (HD) and trochlear dysplasia (TD) are distinct pathologies that share common risk factors including first-born children, females, and history of breech position. Both HD and TD predispose patients to pain, instability, and arthritis. Recent ultrasound studies have demonstrated an association between these pathologies in newborns but it is unclear if the association persists into adulthood. The purpose of this study was to evaluate the incidence of validated features of TD in skeletally mature patients with HD using axial MRI sequences of the knee.
Materials and Methods: 48 patients with symptomatic HD were gender-matched to 48 control patients with symptomatic CAM femoroacetabular impingement (FAI). Patients were skeletally mature with an average age of 31.2 years (range: 15.8-66.2 years). Hip radiographs and MRIs of the hip and knee were analyzed for features of HD and TD, including lateral center edge angle (LCEA), Tönnis angle (TA), anterior center edge angle (ACEA), trochlear depth, lateral trochlear inclination (LTI), tibial tubercle trochlear groove (TTTG), femoral anteversion and posterior lateral condylar angle (PLCA).
Results: HD patients had reduced trochlear depth compared to controls (3.6 mm vs 4.6 mm, p < 0.001), decreased LCEA (13.5 vs 28.5 degrees, p < 0.001), decreased ACEA (13.1 vs 29.5 degrees, p < 0.001) and increased TA (16.3 vs 6.0 degrees, p < 0.00001). There were no differences between groups for femoral anteversion, PLCA, TTTG, LTI or knee pain incidence.
Conclusions: HD patients demonstrated reduced trochlear depth, suggesting that the association between HD and TD may continue into adulthood, and that HD patients may be at higher risk for developing patellofemoral joint disease. Clinicians should consider screening HD patients for symptoms of TD and subsequent imaging of the patellofemoral joint. For patients with both HD and TD, therapeutic approaches should consider the overlap of these conditions, and modify treatment plans accordingly to improve patient outcomes.
Spine 1
OP-034
The effect of idiopathic scoliosis on epidural use and natural delivery during childbirth - a matched cohort study
Jeff Kessler1, Adam Kessler2
1Orthopedics, Kaiser Los Angeles Hospital, Los Angeles, USA, 2Dept of Biology, UCLA, Los Angeles, USA
Introduction and Objective: It has not been well studied what effect having idiopathic scoliosis (IS) has on childbirth. This study’s objective is to assess whether pregnant women with IS have different rates of Caesarean section (CS) & epidural anesthesia (EPI) at child birth vs women without IS
Materials and Methods: 1812 pregnant women with confirmed IS who had child birth were compared to a matched cohort of pregnant women without IS. Chi square analysis & logistic regression analysis (LRA) were done to assess for significant (sig) differences in CS & EPI rates btwn pregnant women with/without IS, & do similar subgroup analysis to assess for differences btwn IS patients both with & without prior spine fusion (PSIF)
Results: Comparison of pts with & without IS demonstrated a sig increased rate of EPI (65% vs 58.5%, p = .0002) in IS pts & a lower CS rate (23.2% vs 26.2%, p = .048). Subgroup comparison of IS pts with & without PSIF showed no diff in CS rate but a much lower EPI rate in PSIF pts at 39.8% vs 65%, p < .0001). LRA showed IS pts had a 27% increased odds ratio (OR) of EPI vs pts without IS, & a 22% decreased OR of CS. However, having IS & PSIF led to a 4x greater OR of CS vs pts without IS, and a 71% decreased OR of EPI. Of note, IS pts with PSIF had a 35% increased OR of CS vs IS patients without PSIF, & a 66% decreased OR of EPI.
Conclusions: IS in no way led to a decreased rate of natural delivery or a lower rate of epidural use. In fact, IS patients had a 27% increased OR of EPI vs non-IS patients & a 29% increased OR of natural delivery. However, IS pts with PSIF had a significantly increased OR of CS and a lower OR of EPI.
Spine 1
OP-035
Younger age at spinal cord detethering is potentially associated with a reduced risk of curve progression in children with early onset scoliosis
Rajiv Iyer1, Adam Fano1, Hiroko Matsumoto1, Rishi Sinha1, Benjamin Roye1, Michael Vitale1, Richard Anderson1
1Columbia University, New York, USA
Introduction and Objective: In early onset scoliosis (EOS) patients with tethered spinal cords (TSC), detethering is commonly performed prior to spinal deformity surgery. The purpose of this study was to investigate whether EOS patient age or curve magnitude at time of detethering was associated with curve progression.
Materials and Methods: EOS patients who underwent detethering at least 2 years prior to index spinal deformity surgery were identified in a multicenter international registry. Radiographs were assessed just prior to detethering (pre-detether) and at most recent visit prior to spinal deformity surgery (most recent post-detether). Due to unequal follow-up in individual patients, Cox regression was utilized to investigate associations between primary variables (age and major coronal curve magnitude) and rate of curve progression.
Results: 37 patients met inclusion criteria, and 18 (mean age: 3.7 ± 2.9 years, 66.7% female, mean follow-up: 3.4 ± 1.3 years) had radiographic data available for analysis. Pre-detether and most recent post-detether major coronal curves were 44.8 ± 18.5° and 47.6 ± 23.9°, respectively. 5 (27.8%) patients had curve progression > 10° at follow-up of 3.2 ± 1.2 years. Patients with curve progression > 10° were older at time of detethering when compared to those without (5.6 ± 2.8 vs. 3 ± 2.7 years, p = 0.084). Regression analysis demonstrated that as age at detethering increased by 1 year, rate of curve progression > 10° increased by 28.6% [95% Confidence Interval (CI) : 0.899; 1.839, p = 0.169]. There was no evidence of association between pre-detethering curve magnitude and rate of curve progression > 10° [HR: 1.027, 95% CI: 0.977; 1.079, p = 0.297].
Conclusions: In EOS patients with TSC, younger age, but not curve size, at time of detethering was associated with lower rate of scoliosis progression. These results indicate a potential role for early spinal cord detethering in EOS but require further investigation with a larger cohort.
Spine 1
OP-036
Pre-operative carbohydrate drink for early recovery in pediatric spine fusion: Randomized control study
Jennifer Bauer1, Kathryn Anderson1, Eliot B. Grigg1
1Seattle Children’s Hospital, Seattle, USA
Introduction and Objective: As rapid discharge protocols for paediatric spine fusion shorten stays, gastrointestinal (GI) limitations including constipation, emesis, and paralytic ileus are uncovered and cause delays in discharge or readmission. A pre-operative carbohydrate drink has been shown to improve perioperative GI symptoms, but has not been examined in paediatric nor spine patients. We aimed to determine if a preoperative carbohydrate drink is safe in paediatric spine fusion patients, and if it improves their comfort scores and time to return of bowel function.
Materials and Methods: We prospectively blindly randomized ASA 1+2 paediatric spine fusion patients > 7yr to either a pre-anaesthesia carbohydrate drink 2 hours prior to surgery, or to a control group of standard 8 hours NPO. We documented time to return to flatus and first bowel movement, as well as GI symptoms such as emesis events or extra treatment such as suppository. We also collected comfort scores perioperatively, spine surgery related variables, and morphine equivalents.
Results: 14 patients were randomized to the control group and 20 to the carbohydrate drink. There was no significant difference between the groups in total anesthesia duration; the drink group averaged 1.9 less levels fused (p = 0.38) and 72cc less EBL (p = 0.13). There were no perioperative complications related to ingestion of a pre-operative drink. The group that received the drink had earlier return of flatus, with 69% vs. 33% return at 24hr (p = 0.04), and 100% by 48hr vs. 100% by 72hr. There was no difference in return of bowel movement prior to discharge (14% control vs 15%, p = 0.9). The drink group reported less nausea on a 0-100 scale at 24hr (p = 0.027), and less anxiety at 24 (p = 0.001) and 36hr (p = 0.017).
Conclusions: Pre-operative carbohydrate drink is safe in paediatric spine fusion patients, improved time to return of flatus, and resulted in improved comfort measures.
Spine 1
OP-037
Elastic lumbar support versus rigid thoracolumbar orthosis for acute pediatric spondylolysis. A prospective controlled study
Ella Virkki1, Milja Holstila2, Terhi Kolari3, Markus Lastikka1, Kimmo Mattila2, Sari Malmi4, Olli Pajulo1, Ilkka Helenius5
1Paediatric Orthopaedic Surgery, Turku University Hospital, Finland, 2Radiology, Turku University Hospital, Finland, 3 Biostatistics, University of Turku, Finland, 4Paediatric Surgery, Satakunta Central Hospital, Finland, 5Orthopaedics and Traumatology, Helsinku University Hospital, Finland
Introduction and Objective: Spondylolysis is the most common cause of low back pain in young athletes. Aim of this study was to compare a rigid thoracolumbar orthosis to an elastic lumbar support in the treatment of acute pediatric spondylolysis in terms of bony union and health-related quality of life (HRQoL) at four months.
Materials and Methods: Fifty consecutive children with acute spondylolysis (mean age 14.2 years, range 10 to 17 years) were prospectively enrolled. Patients were treated with a rigid thoracolumbar orthosis (Boston brace) or with a low-profile, elastic lumbar support. First 14 patients were randomized the remaining 36 chose brace type themselves. Treatment period was four months and all patients were advised to avoid all sports. Treatment outcomes included bony union of the spondylolysis in a CT at 4 months and HRQoL using the SRS-24 outcome questionnaire filled out before and after the treatment.
Results: Out of the 50 patients, 48 completed the treatment protocol. Twenty-eight patients were treated using the Boston brace and 20 patients the elastic lumbar support. Bony union was obtained in 71.4% (20/28) of the Boston brace and in 75.0% (15/20) of the elastic lumbar support group patients. Difference in union rates was not significant (RR 1.14, 95%CI 0.44-2.98, p = 0.785). There was no statistically significant difference in the SRS-24 total or domain scores at the end of follow-up between the treatment groups (p > 0.159 for all comparisons). In the whole cohort the bony union did not predict better HRQoL at the end of the treatment (p = 0.869), although the pain domain improved significantly in the whole cohort (p < 0.001).
Conclusions: A rigid thoracolumbar orthosis did not provide any benefits over an elastic lumbar support in terms of bony union or HRQoL outcomes in children with acute spondylolysis.
Spine 1
OP-038
Closed suction wound drain reduces postoperative opioid consumption in adolescents undergoing pedicle screw instrumentation for idiopathic scoliosis. A randomized, clinical trial
Linda Helenius1, Paul Gerdhem2, Matti Ahonen3, Jenni Jalkanen4, Johanna Syvänen5, Ilkka Helenius6
1Turku University Hospital, Turku, Finland, 2Nya Karolinska, Sweden, 3University of Helsinki, Helsinki, Finland, 4Kuopio University Hospital, Kuopio, Finland, 1Turku University Hospital, Turku, Finland, 6 Department of Orthopaedics and Traumatology, University of Helsinki, Helsinki, Finland
Introduction and Objective: Closed suction subfascial drain is used worldwide after instrumented posterior spinal fusion for adolescent idiopathic scoliosis (AIS). Postoperative drain output has been associated with up to 50% of total blood loss in these patients. There have been no studies evaluating the effects of subfascial drain on decrease in hemoglobin levels nor the effect on opioid consumption and pain. We hypothesized that postoperative hemoglobin change and total blood loss would be larger in the group with subfascial drain. Secondary outcome was pain and opioid consumption.
Materials and Methods: In a randomized, multicenter clinical trial 82 consecutive adolescents undergoing pedicle screw instrumentation for AIS were randomized into 24h submuscular closed suction drain or no drain group at the time of wound closure using the sealed envelope technique (1:1).
Results: The total postoperative blood loss (intraoperative and drain output) was significantly greater in the group with subfascial drain than in the no drain group (1004 ± 535 mL vs. 635 ± 547 mL, p < 0.001). The total blood loss measured in percentage of blood volume was 26% ± 14 in drain and 16% ± 11 in the no drain group (P = 0.0002). The 24h or 48h postoperative decrease in hemoglobin did not differ between the groups (mean 48-hour decrease: 32 ± 15 g/L vs. 36 ± 15 g/L, p = 0.351). Two patients in the drain group and three patients in the no drain group needed allogenic blood transfusion. The mean ± SD 48h opioid consumption was higher in the no-drain group (2.0 ± 0.8 mg/kg vs. 1.5 ± 0.7 mg/kg, p = 0.03).
Conclusions: Use of subfascial drain increases total blood loss after pedicle screw instrumentation but is not associated with decreased hemoglobin level or wound healing issues. However, pain levels and opioid consumption are higher in the group without subfascial drain.
Spine 1
OP-039
Upper instrumented vertebrae (UIV) selection matters: Increased risk of proximal junctional kyphosis when UIV is below T2 in Scheuermann’s kyphosis
Adam Fano1, Hiroko Matsumoto1, Lisa Bonsignore-Opp1, Benjamin Roye1, Lawrence Lenke1, Elizabeth Herman1, Afrain Boby1, Andrew Luzzi1, Peter Newton2, Baron Lonner3, Michael Vitale1, Harms Study Group4
1Columbia University, New York, USA, 2Rady Children’s Hospital, San Diego, USA, 3Mount Sinai Hospital, New York, USA, 4Setting Scoliosis Straight, San Diego, USA
Introduction and Objective: Previous studies have reported risk factors for proximal junctional kyphosis (PJK) in Scheuermann’s Kyphosis (SK) patients undergoing posterior spinal fusion (PSF) ; however, the relationship between UIV location and risk of PJK remains unclear. The purpose of this study was to investigate the association between UIV location and risk of PJK at 2 years following PSF.
Materials and Methods: SK patients who underwent PSF and reached 2 years postop were identified in a multicenter international registry. Those with anterior release, prior spine surgery, neuromuscular comorbidity, or post-traumatic kyphosis were excluded. Location of UIV, and number of levels between UIV and preop kyphosis apex, were determined. Occurrence of PJK (proximal junctional angle ≥ 10° that is ≥ 10° greater than the preop measurement) was recorded.
Results: 91 patients (16.5 ± 1.9 yo, 64.8% male) were included, and all underwent PSF that included the proximal end vertebra of the major kyphosis (MK). Preop and 2-year postop MK was 74.8 ± 11.7° and 45.9 ± 10.4°, respectively. 22 (24.2%) patients developed PJK at 2 years. Patients with UIV below T2 (36.6% vs 14.0%, p = 0.012) had increased risk of PJK when compared to their counterparts. PJK was not associated with preop MK, % MK correction, pelvic incidence (PI), PI-lumbar lordosis mismatch, or symmetry of the fusion construct surrounding the apex (equal # of vertebrae fused above and below). Multiple regression analysis showed that those with UIV below T2 had increased risk of PJK by 2.31 times compared to those with UIV at or above T2, adjusting for distance between UIV and apex (p = 0.045).
Conclusions: These results demonstrate an association between UIV location and PJK in SK patients. SK patients with UIV below T2 have an increased risk of PJK at 2 years postop. This association supports the need for careful consideration of the risks and benefits of UIV below T2.
Spine 1
OP-040
Association of the LBX1 gene promoter methylation in deep paraspinal muscles of patients with idiopathic scoliosis with disease severity
Piotr Janusz1, Małgorzata Tokłowicz2, Miroslaw Andrusiewicz2, Malgorzata Kotwicka2, Tomasz Kotwicki1
1Poznan University of Medical Sciences, Department of Spine Disorders and Pediatric Orthopedics, Poznan, Poland, 2Poznan University of Medical Sciences, Chair and Department of Cell Biology, Poznan, Poland
Introduction and Objective: Idiopathic scoliosis (IS) is a multifactorial disease with significant genetic background. The LBX1 gene polymorphisms are associated with IS. However the pathogenesis of this phenomenon is not established. In recent years, the role of epigenetic factors in the etiopathogenesis of IS has been increasingly investigated. The aim of this study was to evaluate the association of the LBX1 promoter methylation level in deep paraspinal muscles of patients with idiopathic scoliosis with disease severity
Materials and Methods: The study involved 57 girls (171 tissue samples from deep paravertebral muscles, both on the convex and the concave side of the curve and back superficial muscles) who underwent an operation due to IS. Patient subgroups were analyzed according to Cobb angle ≤ 70° (28 cases) vs. > 70° (29 cases). Level of methylation was evaluated in two promoter regions: proximal (28 CpG sites) and distal (23 CpG sites) using the pyrosequencing method.
Results: The methylation level within proximal promoter region was higher in patients with Cobb angle > 70° than in patients with Cobb angle ≤ 70° in 22 of 28 analyzed CpGs (p < 0.05) at the convex side and in 1 of 28 analyzed CpGs (p < 0.05) at the concave side. There was no difference in superficial muscles between the groups.
The methylation level within distal promoter region was higher in patients with Cobb angle > 70° than in patients with Cobb angle ≤ 70° in 3 of 23 analyzed CpGs (p < 0.05) at the convex side, in 7 of 23 analyzed CpGs (p < 0.05) at the concave side and in 7 of 23 analyzed CpGs (p < 0.05) at the superficial muscles.
Conclusions: The level of DNA methylation at the LBX1 promoter region in deep paravertebral muscle tissue may be associated with the severity of idiopathic scoliosis.
Spine 2
OP-041
Mid- and long-term outcomes of lateral thoracotomy: Does the amount of lung parenchyma resection increase the risk of scoliosis? A retrospective review of 129 pediatric patients
Riccardo Sacco1, Damien Fron2, Dyuti Sharma3, Michel Bonnevalle3, Federico Canavese2
1Orthopedic and Trauma Center, Turin, Italy, 2Department of Paediatric Orthopaedic Surgery, 3Department of Paediatric Surgery, Lille University Centre, Jeanne de Flandre Hospital, Lille, France
Introduction and Objective: Scoliosis is a known complication of lateral thoracotomy (LT). We aimed to estimate the risk of post-thoracotomy scoliosis in relation to the amount of lung parenchyma resection (LPR), and the radiographic characteristics of the spinal deformity.
Materials and Methods: 129 paediatric patients met the following inclusion criteria: 1) LT during the study period; 2) minimum clinical and radiographic follow-up of 3 years; 3) any spinal or thoracic deformity diagnosed before the index surgical procedure. Patients were grouped according to underlying disease, age at LT and amount of LPR. The rib vertebral angle difference (RVAD) and vertebral rotation of post-thoracotomy scoliosis were assessed. Kaplan-Meyer survival curves and uni- and multivariate analysis were performed.
Results: 108/129 patients underwent pneumonectomy (9; 9.1%), lobectomy (79; 61.2 %) or segmentectomy (20; 15.5%). The mean age at LT and at last radiological follow-up were 5.5 years (birth-17.8) and 15.2 years (3.4-33.2), respectively. The mean follow up was 10 years (3-28.1). Scoliosis developed on average 5.3 years after LT. The mean Cobb angle was 22.1° (11-90°); it was > 10° in 37/129 patients (28.7%) among which 5/37 (13.5%) had > 45°. Mean vertebral rotation was minimal (16.2°; 2-43°), grade 0 to II. RVAD was 21.4° (8-33°) and 15.3° (2-43°) in patients with > 45° and < 45°, respectively. Sex, age at surgery and amount of LPR were not risk factors for post-thoracotomy scoliosis although younger patients developed more severe deformity with significant progression around age 9-10 years.
Conclusions: Despite the fact that post-thoracotomy scoliosis is not associated with significant rotation, the risk of curve progression > 45° is relatively high. Families of children undergoing LT should be advised about the long term risk of scoliosis development. Regular follow-up is needed as scoliosis can develop several years after LT with or without LPR.
Spine 2
OP-042
Complication risks and costs associated with Ponte osteotomies in surgical treatment of adolescent idiopathic scoliosis: Insights from a national database
Mohammed Shaheen1, Jayme Koltsov1, Samuel A. Cohen1, Joanna Langner1, Japsimran Kaur1, Nicole A. Segovia1, John S. Vorhies1
1Orthopaedic Surgery, School of Medicine, Stanford University, Stanford, USA
Introduction and Objective: Ponte osteotomies (POs) are surgical releases of the posterior spine frequently used to facilitate correction during Posterior Spinal Fusion (PSF) for Adolescent Idiopathic Scoliosis (AIS). Surgeons use POs with variable frequency according to preference. Risks of POs are challenging to assess because of the rare incidence of complications after PSF for AIS. We used a large national administrative claims database to describe trends in PO usage and their effect on costs and complications among AIS patients undergoing PSF.
Materials and Methods: Using ICD-9/CPT codes, we identified patients with AIS who underwent PSF (±PO) between 2007-2015 in a national claims database. Costs and trends in usage of POs were evaluated. Odds of neurological complications, readmissions, and reoperations within 90 days and 2 years were assessed.
Results: We identified 8,881 AIS patients who had undergone PSF, of which 8,193 had 90-day follow-up and 4,248 had 2-years follow-up. Overall, 28.8% had PO. The annual rate of POs increased steadily from 17.3% in 2007 to 35.2% in 2015. A risk-adjusted multivariable logistic regression model demonstrated no relationship between POs and neurological complications within 90 days. POs were associated with higher odds for readmissions (1.52 [1.21-1.91]) and reoperations (2.03 [1.13-3.59]) within 90 days, but there were no differences in the odds of reoperations within 2 years. Median hospital costs were $15,854 (17.4%) higher for patients with POs and multivariable modeling demonstrated POs to be an independent predictor of increased costs.
Conclusions: The annual rate of POs in AIS patients undergoing PSF increased steadily from 2007-2015. POs were not associated with an increased rate of neurological complications but were associated with higher costs and higher rates of readmissions and reoperations within 90 days. By 2 years, differences in reoperation rate were no longer significant.
Spine 2
OP-043
Curve characteristics and clinical outcomes in post-sternotomy/thoracotomy scoliosis undergoing definitive spinal fusion
Joanna Langner1, Teeto Ezeonu1, Abdul-Lateef Shafau1, Japsimran Kaur1, Kiley Poppino2, Claire Shivers3, Sai Chilakapati2, Kimberly Hall1, Meghan Imrie1, Lawrence A. Rinsky1, Anthony Riccio3, John S. Vorhies1
1Orthopaedic Surgery, School of Medicine, Stanford University, Stanford, USA, 2UT Southwestern, Dallas, USA, 3Texas Scottish Rite Hospital for Children, San Diego, USA
Introduction and Objective: Thoracotomy and sternotomy in children are known thoracogenic scoliosis risk factors. This study describes curve characteristics and postoperative outcomes in patients with Post-Chest Incision scoliosis (PCIS) treated with posterior spinal fusion (PSF), which have not been previously reported.
Materials and Methods: A retrospective review of electronic medical records of all patients with PCIS treated with primary definitive PSF was performed at 2 tertiary care pediatric institutions over a 19-year period. Pre and post-operative curve characteristics, operative and hospitalization parameters, rates of neuromonitoring alerts, and other complications were recorded.
Results: 39 patients (61.5% female) were identified. 19 had a sternotomy alone; 13 had a thoracotomy alone; 7 patients underwent both surgical approaches. Mean age at time of chest surgery was 2.5 years (range: 1.0 days-14.2 years). Leading cause of chest surgery was cardiac malformation (74.4%). 84.6% of patients had a main thoracic curve (mean cobb angle 71.6°, range: 40.0°-116.0°). 15.4% had a main lumbar curve (mean cobb angle 75.7°, range: 59.0°-83.2°). Mean coronal deformity angular ratio was 15.7. Mean thoracic kyphosis was 39.9° (range: 3.7°-84.0°). Majority of thoracic curves (71.8%) were apex right. 19.0% of patients with prior thoracotomy had rib fusions. Mean age at time of spinal fusion was 14.0 years (range: 8.2-19.9 years). 36 patients had posterior fusions; 3 patients had combined anterior/posterior arthrodesis. Mean of 10.7 levels were fused (range: 7-14). Mean coronal curve correction measured at first postoperative encounter was 53.4% (range: 8.5%-78.0%). There were 5 (12.8%) neuromonitoring alerts and 2 (5.1%) patients with transient postoperative deficits. At an average follow-up time of 3.1 ± 2.4 years, 17 complications (13 Medical, 4 surgical) were noted in 10 patients for a 25.6% overall complication rate.
Conclusions: Right-sided kyphotic thoracic curves predominate in patients with PCIS undergoing PSF. Though good coronal and sagittal plane deformity can be expected following a fusion procedure, post-operative complications are not uncommon.
Spine 2
OP-044
Pediatric cervical spine fusions: Opportunity for improvement
Edward Compton1, Stephen Stephan2, Kenneth Illingworth2, David Skaggs2, Lindsay Andras1
1Orthopaedics, Children’s Hospital Los Angeles, Los Angeles, USA, 2Cedar Sinai Medical Center, Los Angeles, USA
Introduction and Objective: Although the pediatric population typically has a high union rate, the cervical spine has a reputation for frequent nonunions, as high as 38% in some prior series. Our purpose was to examine the rate and risk factors for nonunion in the pediatric cervical spine.
Materials and Methods: Retrospective review of all patients with ≥ 1 year follow-up undergoing cervical spinal fusion between January 2004-December 2019 at a tertiary pediatric hospital. Nonunion was defined as an absence of radiographic union as assessed by the attending surgeon that required additional surgery
Results: 1 patient (mean age: 8.5 ± 4.9 years) met inclusion criteria. Mean follow-up was 52.4 ± 40.5 months (range: 12-170 months). 31 fusions (44%) included the occiput. 45 patients (63%) had instrumentation, while 26 patients (37%) had uninstrumented fusions. 53 (75%) patients had a halo for a mean of 98.0 ± 47.7 days. The incidence of nonunion was as follows: overall = 8/71 (11.3%); posterior fusion = 13.3% (8/60); anterior fusions = 0% (0/6); and anteroposterior fusions = 0% (0/5). Although it did not achieve significance independently, the rate of nonunion was nearly 4 times higher in fusions involving the occiput (occipitocervical fusions: 19.4%; 6/31 vs cervical alone: 5.0%; 2/40; p = 0.07) and the rate of nonunion was 3 times higher in uninstrumented fusions (19.2%; 5/26) than instrumented fusions (6.7%; 3/45) (p = 0.13). In patients with uninstrumented fusion to the occiput, nonunion rate was 27.8% (5/18), which was higher compared to those who did not (5.7%; 3/53) (p = 0.02). Incidence of nonunion was similar in patients who received autograft (11.7%; 7/60) compared to allograft alone (9.1%; 1/11) (p > 0.999)
Conclusions: The nonunion rate in pediatric cervical spine fusions remained high despite frequent use of halo immobilization and autograft. Patients with uninstrumented occipitocervical fusions are at particularly high risk with more than 1 in 4 developing a nonunion.
Spine 2
OP-045
Do rib or spinal proximal anchors in growing rod constructs yield more length gain over time?
Vivian Chen1, David Skaggs2, Edward Compton1, Kenneth Illingworth2, John Smith3, Francisco J. Sanchez Perez-Grueso4, Scott Luhmann5, Michael Vitale6, Mark Erickson7, Pediatric Spine Study Group8, Lindsay Andras1
1Children’s Orthopaedic Center, Children’s Hospital Los Angeles, Los Angeles, USA, 2Orthopaedic Surgery, Cedars-Sinai Medical Center, Los Angeles, USA, 3Orthopaedic Surgery, Primary Children’s Hospital, Salt Lake City, USA, 4Orthopaedic Surgery, La Paz University Hospital, Madrid, Spain, 5Washington University in St. Louis, Orthopaedic Surgery, St. Louis, USA, 6Columbia University Vagelos College of Physicians and Surgeons, Orthopaedic Surgery, New York, USA, 7Children’s Hospital Colorado Anschutz Medical Campus, Aurora, Orthopaedic Surgery, Aurora, USA, 8Pediatric Spine Foundation, Pediatric Spine Study Group, Valley Forge, USA
Introduction and Objective: The purpose of this study was to compare the impact of rib-based vs spinal-based proximal anchors on spine length in magnetic-controlled growing rods (MCGR) and traditional growing rods (TGR) patients.
Materials and Methods: Retrospective cohort study from a multicenter database of patients treated with MCGR or TGR with > 2-year follow-up. Prior spinal instrumentation or vertical expandable prosthetic titanium rib devices (VEPTR) patients were excluded. Subjects were categorized into rib-based anchors or spine-based anchors fixation groups. Rib patients were case-matched with spine patients based on age (difference < 0.5 years) and follow-up (difference < 150 days).
Results: 64 patients met inclusion criteria (32 rib; 32 spine). Mean index instrumentation age was 7.7 years; mean follow up was 2.9 years. The mean Cobb angle change between pre-instrumentation to final follow-up/pre-definitive fusion was similar between groups [rib = 24°; spine = 32o (p = 0.13)]. From pre-instrumentation to post-instrumentation, the mean T1-S1 length gain was similar between groups (rib = 3.53 cm, spine = 4.70 cm; p = 0.08), as was the mean T1-T12 length (rib = 1.96 cm, spine = 2.56 cm; p = 0.24). From post-instrumentation to final follow-up/pre-definitive fusion, the mean T1-S1 length gain was similar between groups (rib = 2.34 cm, spine = 1.81 cm; p = 0.53), as was the mean T1-T12 length gain (rib = 1.23 cm, spine = 1.30 cm; p = 0.91). From pre-instrumentation to final follow-up/pre-definitive fusion, the mean T1-S1 length gain was similar between groups (rib = 5.87 cm, spine = 6.51 cm; p = 0.50) as was mean T1-T12 length gain (rib = 3.19 cm, spine = 3.85 cm; p = 0.54). The mean difference in T1-T12 length (pre-instrumentation to final follow-up/pre-definitive fusion) between groups was 0.65 cm (p = 0.46). The mean difference in T1-S1 length (pre-index and pre-definitive fusion) between rib and spine groups was 0.66 cm (p = 0.32).
Conclusions: The mean difference in T1-S1 and T1-T12 length between groups with rib or spine anchors was less than 0.7 cm and was not significant. Rib and spine proximal anchors performed similarly in increasing spine length in distraction based growing rods.
Spine 2
OP-046
A comparison of SRS and PROMIS questionnaires in patients presenting with adolescent idiopathic scoliosis
Yousi Oquendo1, Nadine Javier1, Xochitl Bryson1, Joanna Langner1, Clayton Maschhoff1, Christian Calderon1, Ann Richey1, John S. Vorhies1
1Orthopaedic Surgery, Stanford University School of Medicine, Palo Alto, USA
Introduction and Objective: The Patient-Reported Outcomes Measurement Information System (PROMIS) is a patient reported outcome measure that is gaining in popularity within the orthopaedic sub-specialties given its broad applicability to a number of injuries and deformities. In this study, we aimed to evaluate the correlation and performance of the Scoliosis Research Society (SRS-30) survey domains compared to the PROMIS questionnaire domains in patients presenting with adolescent idiopathic scoliosis (AIS).
Materials and Methods: Patients between 10 and 18 years old presenting with AIS to an outpatient pediatric orthopaedic clinic affiliated with a large academic medical center completed the SRS-30 and PROMIS surveys during or prior to their visit, and major curve magnitude (MCM) was documented for each patient. Pearson’s correlation coefficients (r) was calculated to compare similar SRS and PROMIS domains.
Results: Seventy-five patients were included. Mean age was 14 years and mean MCM was 26.7 degrees. Moderate correlations existed between SRS Activity and PROMIS Mobility domains (r = 0.46, p < 0.01), SRS Pain and PROMIS Pain Behavior domains (r = -0.56, p < 0.01), SRS Mental and PROMIS Anxiety domains (r = -0.59, p < 0.01), and SRS Appearance and PROMIS Physical Stress Experience domains (r = -0.50, p < 0.01). Strong correlations were found between SRS Pain and PROMIS Pain Interference domains (r = -0.69, p < 0.01) and SRS Mental and SRS Depression domains (r = -0.74, p < 0.01).
Conclusions: Scores in several PROMIS domains are moderately to strongly associated with similar SRS-30 domains. As the PROMIS questionnaire gains in popularity, comparison of outcomes between studies will become more complex. Relationships between the PROMIS questionnaire and the previously more ubiquitous SRS-30 questionnaire can be used to compare results across studies that use these different patient reported outcome measures.
Sports 1
OP-047
Long-term minimum 15-year follow-up after lateral discoid meniscal preservation surgery in children and adolescents
Laura Lins1, Aliya Feroe2 3, Brian Yang4, Kathryn Williams3, Sophia Kocher5, Lyle Micheli2 3, Mininder Kocher2 3
1Orthopaedic Surgery, UW School of Medicine and Public Health, Madison, USA, 2Harvard Medical School, Boston, USA, Orthopaedic Surgery, Boston Division of Sports Medicine, Children’s Hospital, Boston, USA, 4Orthopaedic Surgery, Hospital for Special Surgery Main Hospital, New York, USA, 5Dartmouth College, Hanover, USA
Introduction and Objective: Lateral discoid meniscus (LDM) is a congenital variant typically affecting the lateral meniscus of the knee, historically treated with total meniscectomy when symptomatic. Due to observed degenerative changes, rim-preserving procedures are preferred using arthroscopic saucerization and, when indicated for instability, meniscal repair. The purpose of this study was to examine long-term patient-reported outcomes after meniscal-preserving surgery for symptomatic LDM.
Materials and Methods: Ninety-eight patients treated arthroscopically for LDM at a single institution at a minimum of 15 years ago were retrospectively identified and contacted by mailers and telephone to participate. Subjective functional outcomes and patient satisfaction data were collected using a questionnaire that included the validated IKDC Subjective Knee Evaluation Form, Lysholm Score, Marx Activity Rating Scale, Tegner Activity Score, and WOMAC Osteoarthritis Index. Patient and surgical characteristics and patient-reported outcomes were summarized.
Results: Of the 46 patients (47%) successfully contacted, 25 (54%) completed the questionnaires. Mean (± SD) age at initial surgery was 10.8 (± 3.4) years and 30.3 (± 3.7) years at final follow-up. Mean (± SD) follow-up time from initial surgery was 19.5 (± 2.8) years (range, 16-27). Patient-reported outcomes included: IKDC 77.4 ± 17.2, Lysholm 78.6 ± 21, Tegner Activity 7 (out of 10), Marx Activity Rating Scale 8 (out of 10), and WOMAC 7.6 ± 11.3. Eleven (44%) cases underwent subsequent LDM-related surgery on the ipsilateral knee (s). There were no cases of total knee replacement (Table 1).
Conclusions: Overall, patient-reported outcomes were favorable at a minimum of 15-year follow-up after rim-preserving saucerization for LDM. While two-thirds of patients were satisfied with their surgical outcomes, nearly half of patients underwent revision saucerization with or without meniscal repair. Subsequent long-term follow-up studies with objective outcome measures are important to further elucidate the natural history of LDM and understand how rim-preserving procedures may prevent the development of degenerative conditions.
Postoperatie outcomes by discoid and surgery (N = 26).a
Data are presented as n (%). Discoid type was not documented for 4/30 knees (13%). S = saucerizationb, MR = meniscal repair; bBased on Watanabe Classification; cAt the time of questionnaire cmpletion. Denominator is the number of knees having undergone S or S+MR operation within each discoid type (i.e., the value in the “Index Surgery” column in the same row); dAnd cartilage microfracture and drilling (n = 1); eAnd plica excision (n = 1), lysis of adhesions synovectomy (n = 1); fAnd lysis of adhesions (n = 1).
Sports 1
OP-048
Meniscus tears in pediatric patients with ACL injury: Incidence, management, and outcome
Luca Rigamonti1 2, Nathaniel A. Bates1, Nathan D. Schilaty1, Bruce Levy1, Michael Stuart1, Marco Bigoni2, Todd Milbrandt, MD1, Aaron Krych1
1Orthopaedic Surgery, Mayo Clinic, Rochester, USA, 2Orthopaedic Surgery, University of Milano-Bicocca, Milan, Italy
Introduction and Objective: The incidence of pediatric Anterior Cruciate Ligament (ACL) injuries have increased over the last decades. Treatment of associated lesions, together with ligament reconstruction, is crucial for satisfactory clinical outcomes and prevention of joint degeneration. The purpose of this study is to characterize meniscus tears associated with ACL injury, and identify which variables are related to their presence and evaluate the rate of postoperative re-tear.
Materials and Methods: All patients under age 18 who underwent ACL reconstruction (2000-2018) at a single institution were reviewed at minimum 2-year follow-up. Patient demographics, surgical characteristics, and postoperative retear rates were recorded. Multivariate logistic regression was used to highlight factors associated with primary meniscal lesions; Kaplan-Meier analysis was performed to determine the rate of meniscal survival.
Results: Of 272 ACL reconstructions (171 females, 101 males, mean age 15.4), the overall rate of meniscus injury was 66.5%, lesions were more frequently lateral (79.6%), 23.3% of them were bilateral. Posterior horn was most involved (71.5% f lateral and 91.1% medial), vertical longitudinal was the most frequent type (25.8% lateral and 48.1% medial). Younger patients (p = 0.047) and contact injury (p = 0.027) were associated with higher risk for meniscus tear. Lesions were most frequently repaired (44.7% lateral and 59.5% medial), followed by partial meniscectomy (23.7% and 12.6%). Overall, the rate of second meniscal tear after primary ACL reconstruction was 3.4% at 10 years and 8.0% at 20 years after surgery. 58.7% of all the secondary meniscus tears were concomitant with ACL reinjury.
Conclusions: Meniscus tear at the time of primary ACL injury is common in pediatric patients. Younger patients and contact injuries are associated with higher risk. Most meniscal tears can be repaired. Restoration of knee stability to prevent second ACL injury is the most important factor to avoid additional meniscus tears.
Sports 1
OP-049
Delays in anterior cruciate ligament reconstruction are associated with higher rates of meniscus and chondral pathology in skeletally immature patients
Andrew Pennock1, Matthew Milewski2, Lauren Hutchinson2, Patricia Miller2, Mininder Kocher2
1Rady Children’s Hospital - San Diego, San Diego, USA, 2Boston Children’s Hospital, Boston, USA
Introduction and Objective: ACL reconstruction timing remains controversial with some studies favoring early reconstruction within 60-to-90 days of injury to lessen the probability of chondral and meniscus pathology. This study assessed the correlation between meniscus and chondral pathology and delays in surgical treatment, and determined if surgical delays lead to higher rates of meniscus debridement and a higher need for cartilage treatment among skeletally immature patients with ACL tears.
Materials and Methods: Skeletally immature patients diagnosed with ACL tears between 2016 and 2020 from 10 institutions were enrolled. Univariable and multivariable logistic regression analysis was performed.
Results: Analysis included 747 patients, and 56.6% had a meniscus tear. Tears were more likely to occur in older patients (chronologic age 12.6 versus 12.0; p ≤ 0.001). Patients with a bone age greater than 13 years were 2 times more likely to have a meniscus tear (OR = 2.0; p ≤ 0.001). No association was detected between continuous time to surgery and likelihood of a meniscus tear. However, patients who had surgery greater than 60 days from injury were 1.5 times more likely to have a meniscal tear (OR = 1.54; p = 0.006). Sixty-five chondral injuries in 48 patients were identified. Patients who had surgery more than 90 days from injury were 3 times more likely to have a chondral injury (OR = 3.3; p ≤ 0.001). Furthermore, patients with a bone age greater than 13 years had 7 times the odds of chondral injury (OR = 6.8; p = 0.002) compared to younger patients. Nineteen of 48 patients (40%) with chondral injury required treatment, but there was no association between time from injury to surgery and the need for treatment (p = 0.55).
Conclusions: Older patients and those with longer delays to surgery were more likely to have meniscus and chondral pathology at the time of ACL reconstruction. This data suggests that older adolescent patients may benefit from earlier surgical intervention.
Sports 1
OP-050
Quadriceps tendon anterior cruciate ligament reconstruction in skeletally immature patients: Clinical and patient reported outcomes
Sofia Hidalgo Perea1, Danielle E. Chipman1, Frank Cordasco1, Daniel Green1
1Hospital for Special Surgery Main Hospital, New York, USA
Introduction and Objective: The aim of this study is to evaluate 2-year clinical and patient-reported functional outcomes of primary anterior cruciate ligament reconstruction (ACLR) with soft tissue quadriceps tendon autograft (QTA) in skeletally immature patients.
Materials and Methods: Consecutive skeletally immature patients who underwent ACLR utilizing full thickness soft tissue QTA (without bone plug) were included. The ACLR technique was predicated upon skeletal age and included all-epiphyseal (AE) and complete transphyseal (CT). Patients were followed for a minimum of 24 months with successive clinical visits or contacted via telephone. Information regarding the return to sports and concomitant or subsequent surgical procedures was collected.
Results: The final cohort included 60 adolescent patients aged 11.1 to 17.1 (13.9 ± 1.2) with a minimum follow-up of 2 years. One patient was lost to follow-up. Twenty-one (35%) patients underwent AE and 39 (65%) underwent CT ACLR. Additionally, 35 (58%) underwent lateral extra-articular tenodesis using the iliotibial band (ITB) with a modified Lemaire technique. The rate of graft failure was 0%. Ten patients (17%) had additional surgical procedures. The mean KT-1000 at 2-year follow-up was -0.36 ± 0.75. The median Pedi-IKDC, HSS Pedi-FABS, and SANE scores were 91, 27, and 96, respectively. At 2 years post-operatively, 90% of patients reported returning to sports.
Conclusions: This study reveals that QTA ACLR had a lower failure rate when compared to previously reported studies of ACLR with hamstring tendon autograft. Based on these results, we recommend considering this technique for skeletally immature patients undergoing ACLR.
Sports 1
OP-051
Does harvesting of the semi tendinous tendon really spare the gracilis tendon in pediatric ACL reconstruction?
Testory Maxime1, Cavaignac Etienne1, Jérôme Sales de Gauzy1, Franck Accadbled1
1CHU de Toulouse, France
Introduction and Objective: Use of hamstring tendons is growing, particularly the semitendinosus in the semitendinosus (ST) technique. The aim of the study was to measure the surface area of the gracilis tendon in children who had undergone arthroscopic reconstruction of the anterior cruciate ligament (ACL) using a ST tendon graft. Our hypothesis was that the gracilis tendon could sometimes be unintentionally and iatrogenically sectioned.
Materials and Methods: Fifty patients who had undergone an MRI preoperatively and postoperatively at one year from the surgery and who had been operated between January 2017 and March 2019 were included. The MRIs were examined using syngo.via image processing software. The surface area of the gracilis tendon was measured on fat-saturated T2-weighted axial views at the widest point of the medial epicondyle of the femur. Age, sex, body weight, and height were documented.
Results: One hundred MRIs of 50 knees were reviewed, from 34 boys (68%) and 16 girls (32%). The mean age was 14.5 years (10-18). The gracilis was visualized in all cases at one year postoperatively. The average tendinous surface area of the gracilis before the surgical procedure was 7.13 mm2 versus 8.73 mm2 at one year, representing an increase of 1.6 mm2 (p = 0.0003).
Conclusions: This study demonstrated that harvesting of the semitendinosus for the purpose of ACL reconstruction was a safe technique that preserves the gracilis. We also observed a trend to hypertrophy of the gracilis after harvesting, which opens prospects for further studies.
Sports 1
OP-052
Decrease in lateral femoral notch sign depth following ACL reconstruction in pediatric patients
Nicolas Pascual-Leone1, Danielle E. Chipman1, Daniel Green1
1Hospital for Special Surgery Main Hospital, New York, USA
Introduction and Objective: The lateral femoral notch sign (LFNS) is frequently seen following an anterior cruciate ligament (ACL) rupture. Previous studies have noted that while the depth of the LFNS did not decrease over time, the total area did decrease in the adult population, indicating the healing pattern of the lateral femoral condyle. The purpose for this study is to analyze the change in LFNS following ACL reconstruction in the pediatric population.
Materials and Methods: This is a retrospective cohort study. 132 pediatric patients undergoing primary ACL reconstruction were collected. Pre-operative MRI was reviewed for the presence of a LFNS. Patients were included if they had an LFNS greater than 1.5 mm. Patients were excluded if they did not have post-operative MRI imaging at time of data collection. Depth of the LFNS was measured on pre-operative and post-operative (6-month) MRI. Independent sample t-tests were used to compare pre- and post-operative values. Statistical analysis was performed using IBM SPSS Statistics version 22 for windows.
Results: A LFNS greater than 1.5 mm was found in 8 pre-operative MRIs. The average age at surgery was 15.1 ± 1.2. Pre-operative MRI demonstrated a LFNS of 1.663 ± 0.160 mm. At 6-month follow up, knee MRI showed a LFNS of 1.188 ± 0.376 mm. This decrease in depth of 0.475 mm was found to be statistically significant (p = 0.009).
Conclusions: This study found within 6-months, LFNS decreases by 0.475 mm in depth. With this significant decrease in depth, future studies should focus on characterizing the healing pattern of the lateral femoral condyle following ACL rupture with the use of additional imaging modalities and timepoints. A previous study in adult patients undergoing ACL reconstruction have found that the depth of the LFNS does not decrease in the post-operative period. This study suggests that LFNS may heal in the pediatric population following ACL reconstruction.
Sports 1
OP-053
Pediatric partial ACL tears: Outcomes and management practices
Megan Hannon1,2, Nicholas Sullivan1,2, Emily Chang1,2, Patricia Miller1,2, Melissa Christino1,2, William Meehan1,2
1Orthopaedics, Sports Medicine, Boston Children’s Hospital, Boston, USA
Introduction and Objective: Partial anterior cruciate ligament (pACL) injuries are a challenge diagnostically due to a lack of a clinically relevant definition and insufficient outcome data. Additionally, the sensitivity of MRI for pACL diagnosis is questionable. This study seeks to identify potential risk factors and the mean time for progression to ACL insufficiency.
Materials and Methods: Three hundred and sixty-five patients between the ages of 8 and 18 presenting to the orthopedic department at a level 1 pediatric trauma center with a pACL tear diagnosis between 1/1/2009 and 12/31/2019 were analyzed. Patients were prospectively contacted to complete a provider-created survey. Once the survey was returned, chart review began.
Results: Amongst the 97 patients that completed the survey, twenty-one progressed to ACL insufficiency for a failure rate of 21.6% (95% CI = 14.2-21.4%) at a median time of 4 months (IQR, 3.0-5.4 months). There were no detected differences of demographic, clinical, radiographic, or initial conservative treatment characteristics amongst the group that progressed to ACL insufficiency and those that did not. Presenting concomitant meniscal injury was 24%. Initial non-operative treatment was 84%. Thirty percent of those went onto operative repair. Bracing and physical therapy were near universal (> 90%), ranging 6 weeks to a year, median of 3 months. In the follow up survey of all patients, there was ongoing instability (16%) and knee pain (30%).
Conclusions: In clinical practice, partial ACL tears carry a substantial rate of progression to full ACL insufficiency, especially within the first 6 months of injury. Despite the variability in management, the progression to full ACL insufficiency exists at similar rates. This is the first study to detail characteristics and outcomes of a clinically defined cohort of pACL tears. Future focus to delineate characteristics to identify those high risk of pACL tear progression is needed to support better targeted management.
Sports 2
OP-054
Return to preinjury level of sports and the quality of life after tibial spine avulsion fracture with at least 2 years of follow-up
Maija Jääskelä1,2, Marco Turati3,4,5,6, Lasse Lempainen7,8, Antoine Henri9, Aurelien Courvoisier3,4, Nicolas Bremond3,4, Franck Accadbled6,9, Jaakko Sinikumpu1,2,6
1Pediatric Surgery and Orthopaedics, Oulu University Hospital, Oulu, Finland, 2University of Oulu, PEDEGO Reserach Unit, Oulu, Finland, 3Paediatric Orthopaedic Surgery, Hospital Couple Enfant, Grenoble Alpes University, Grenoble, France, 4Transalpine Center of Pediatric Sports Medicine and Surgery, University of Milano-Bicocca, Monza, Italy, 5School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy, 6EPOS Sport Group, 7Sports Hospital Mehiläinen, Turku, Finland, 8Orthopaedics and Traumatology, University of Turku, Turku, Finland, 9Department of Orthopedics and Traumatology, Hospital des Enfants, Toulouse University Hospital, Toulouse, France
Introduction and Objective: There is no wide understanding about the recovery of tibial spine avulsion fractures, as regards return to sports and overall satisfaction. The purpose was to analyze return to preinjury level of sports, and subjective knee-specific recovery and the quality of life.
Materials and Methods: All children and adolescents with a tibial spine fracture, treated in four European institutions in 2000-2018 were enrolled to this observational EPOS Sport Group study. Ability to return to preinjury level of sports at least 2 years postoperatively was the main outcome. Subjective knee-specific recovery and quality of life were another outcomes. The results were adjusted for potential confounders. Altogether 95 patients out of 173 (55%) participated to long-term follow-up. Patients operated upon open surgery (n = 47) vs. arthroscopic surgery (n = 35) were separately analyzed. 13 patients were treated nonoperatively.
Results: Great majority (82%) of all operatively treated cases were able to return to preinjury level of sports. Open surgery associated with faster return (median 12 weeks vs. 22.5 weeks after arthroscopy, p < 0.001). It also associated with lower risk of failure in returning to preinjury level of sports (OR 0.12; 0.02 to 0.72; p = 0.02). Among operated cases, higher displacement (8.1mm) was found in patients with open surgery, compared to arthroscopy (5.3mm, p < 0.001). Lower displacement associated with nonoperative care (p < 0.001). Among nonoperated cases, the risk of failure in returning to preinjury level of sports increased 30% by every additional year of age (p = 0.034).
Conclusions: Good recovery and satisfaction were found after tibial spine avulsion fractures among junior athletes; open surgery resulted in faster return to sports and lower rate of failure in returning to preinjury sports, as compared with arthroscopic care.
Sports 2
OP-055
Growth physis sparing medial patellofemoral ligament reconstruction in children with open physes
Thomas Kappe1, Janina Leiprecht1, Thomas Caffard1, Heiko Reichel1
1Department for Orthopedic Surgery, University of Ulm, RKU, Ulm, Germany
Introduction and Objective: Medial patellofemoral ligament (MPFL) reconstruction has been proposed for recurrent patella dislocation, with an ongoing debate concerning the anatomic femoral insertion of the MPFL in relation to the physis. The aim of the present study therefore was to investigate the results of physis sparing MPFL reconstruction in children with open physes.
Materials and Methods: Thirty children with a mean age of 13.5 ± 2.1 years, who received physis sparing MPFL reconstruction using a free gracilis tendon autograft with a biplanar fluoroscopically confirmed insertion distal to the physis, were included into the present study. Apart from redislocation and clinical outcome, the location of the femoral bone tunnel, LDFA, and sulcus angle were studied on magnetic resonance imaging (MRI) scans of the knee.
Results: At a mean follow up of 30 months, there was one case of redislocation. On MRI, the physis was unharmed in all cases. The minimum distance of the femoral bone tunnel from the physis was 2.5 ± 1.8 mm. No significant differences were observed for the LDFA (80.4 ± 1.4 and 80.0 ± 1.5, respectively). A small yet significant decrease was observed for the sulcus angle (158.0 ± 8.7 and 156.3 ± 8.3, p = 0.02). Mean KOOS scores were: symptoms 84.7 ± 15.8, stiffness 93.2 ± 11.5, pain 83.6 ± 28.1, activities of daily living 96.3 ± 6.6, sports and recreation 83.2 ± 18.4, and quality of life 68.4 ± 25.0. The mean Kujala score was 92.2 ± 14.0.
Conclusions: Physis sparing MPFL reconstruction yields good clinical results, an acceptable complication rate, and does not lead to growth disturbances. If the anatomic femoral insertion point is used, the femoral tunnel has to be distal to the physis. In case of recurrent patella dislocation, physis sparing MPFL reconstruction can thus be recommended in children with open physes.
Sports 2
OP-056
Incidence of 2nd surgery after medial patellofemoral ligament reconstruction with osteochondral fracture fixation in pediatric patients after patella dislocation
Alexandra Aitchison1, Sofia Hidalgo Perea1, Lindsay Schlichte1, Daniel Green1
1Hospital for Special Surgery Main Hospital, New York, USA
Introduction and Objective: Osteochondral fractures occur in 5-15% of acute or recurrent patellar dislocations. The aim of this study was to determine the incidence of recurrent instability and second surgery following osteochondral fracture fixation (OFF) with concomitant medial patellofemoral ligament reconstruction (MPFLR).
Materials and Methods: We conducted a retrospective study of 365 MPFLR performed by a single surgeon between 2008 and 2019. Forty-one knees underwent MPFLR with OFF. Demographic data, surgical details, clinical follow-up, and subsequent surgical procedures were collected.
Results: The average age at surgery was 14.6 (10.7 - 19.6) years. The average length of clinical follow-up was 2.6 (0.7 - 7.0) years. The average number of biodegradable fixation nails used was 4.4 (2-8) nails. Thirty fractures were fixed to the patella and 10 were fixed to the lateral femoral condyle or trochlea. There were two reports of recurrent instability (5%) at the latest follow-up. Eleven (28%) patients required a second surgery on the ipsilateral knee, and underwent chondroplasty (n = 10), removal of biodegradable fixation nails (n = 4), removal of hemi-epiphysiodesis or TTO hardware (n = 1), revision MPFL with tibial tubercle osteotomy (n = 1), or lateral meniscus repair (n = 1). Nine patients (23%) underwent a second surgery for cartilage damage or removal of nails. The mean time to second surgery was 40.0 (11-82.7) weeks. The four patients who required nail removal had significantly more implanted nails (7 ± 1.7) than patients who did not (4.1 ± 1.6, p < .05).
Conclusions: Second procedures most commonly involved debridement of a small, unhealed portion of the osteochondral fracture. At 2.6-year follow-up, only 2% of patients had failure of their OFF leading to a cartilage restoration procedure. OFF in adolescents with patellofemoral instability can be effectively treated with fixation and simultaneous MPFLR. This study demonstrates a low incidence of recurrent instability after MPFLR and OFF in a pediatric population.
Sports 2
OP-057
Technique variation for MPFL reconstruction in skeletally immature patients: Data from the JUPITER cohort
Benton Heyworth1, Sofia Hidalgo Perea2, Daniel Green2, Matthew Veerkamp3, Eric Wall3, Philip Wilson4, Beth Shubin Stein2, Shital Parikh3
1Boston Children’s Hospital, Boston, USA, 2Hospital for Special Surgery Main Hospital, New York, USA, 3Cincinnati Children’s Hospital Medical Center, Cincinnati, USA, 4Scottish Rite for Children, Dallas, USA
Introduction and Objective: Medial patellofemoral ligament reconstruction (MFPLR) is among the most popular surgical options for patellofemoral instability in pediatric and adolescent patients. The study purpose was to describe demographic and clinical characteristics of skeletally immature PFI patients undergoing MPFLR and examine the variation in surgical technique utilized by 20 pediatric orthopedic or sports medicine surgeons with different experience levels and specialty training backgrounds.
Materials and Methods: All operative records of skeletally immature patients enrolled between 2016 to 2021 in the prospective multi-center JUPITER (Justifying Patellar Instability Treatment by Early Results) study were reviewed, consisting of subjects from 13 different tertiary care academic centers. Inclusion criteria were open physes and a primary, single-stage MPFLR.
Results: Of the 1232 knees, 205 (53% female) met inclusion criteria. The average age was 13.6 ± 1.8 (5.1-19.0) years. 47% of surgeons utilized autograft, while 53% utilized allograft. Suture anchors (including small tenodesis screws) were the most popular fixation technique (61%), followed by the use of tunnel under a bone bridge (37%). Most surgeons utilized 2 suture anchors (59%). Interference screws were the most popular femoral fixation technique (84%), followed by suture anchors (12%). Most surgeons used either 1 interference screw (97%) or 1 suture anchor at the femur (96%). In addition to MPFLR, 15% of patients underwent osteochondral fracture treatment. Lateral retinacular release was performed in 13% of cases and lateral retinacular lengthening in 2%. 10% of patients underwent concomitant hemi-epiphysiodesis for genu valgum, 3% underwent medial quadriceps tendon-femoral ligament reconstructions, and 3% underwent a Grammont realignment procedure.
Conclusions: Variation in the technical aspects of MPFLR in skeletally immature patients is substantial among this cohort of orthopedic surgeons. Given the well-established importance of decreasing variation for healthcare cost containment and optimization of outcomes, sub-stratified analyses are needed to better elucidate the most favorable techniques.
Sports 2
OP-059
Cartilage repair in the skeletally immature knee: A comparative study of different surgical techniques
Ioannes Melas1,2, Dimitrios Metaxiotis3, Michael Iosifidis1,2
13rd Department of Orthopaedic Surgery,European Interbalkan Medical Centre, Thessaloniki, Greece, 2OrthoBiology Centre, Thessaloniki, Greece, 32nd Orthopaedic Department, Papageorgiou General Hospital, Thessaloniki, Greece
Introduction and Objective: Articular cartilage defects of the knee in children and adolescents can be managed by a variety of methods. In the present study we sought to assess the outcomes of skeletally immature patients with knee chondral lesions treated operatively using bone marrow stimulation and cell-based procedures.
Materials and Methods: A consecutive series of 38 subjects with open physes about the knee, who underwent cartilage repair surgery for the treatment of defects located in the articular surface of the tibiofemoral or the patellofemoral joint, were included in this study. 21 patients (group A) received microfracture or autologous matrix-induced chondrogenesis (AMIC), while implantation of autologous chondrocytes (ACI) or adipose-derived mesenchymal stromal/stem cells (Ad-MSCs) was performed in 17 cases (group B). The cohort was followed for 3.4 ± 2.2 years postoperatively and functional outcome evaluation was based on the child and adolescent modification of the International Knee Documentation Committee subjective form (pedi-IKDC) and Tegner Activity Scale (TAS).
Results: A significant improvement was documented for both groups at the time of the last follow-up visit as compared to their preoperative values in both outcome measures; the mean pedi-IKDC score increased from 63.1 ± 6.8 to 87.9 ± 5.6 with the TAS raising from 5.8 ± 1.6 to 8.6 ± 1.0 overall (p < 0.001). Group B showed a greater amount of change (pedi-IKDC: 23.8 ± 5.5, TAS: 2.2 ± 0.8) than group A (pedi-IKDC: 22.6 ± 5.8, TAS: 2.0 ± 0.7), but this difference was not found to be of statistical significance.
Conclusions: Repair of chondral damage in skeletally immature knees utilising different operative management strategies demonstrated overall favourable outcomes. In comparison, cell-based options had better, though not statistically significant, results than bone marrow stimulation interventions.
Sports 2
OP-060
Infrapatellar realignment for patellar subluxation in the skeletally immature child
John Handelsman1, William Facibene2
1 Orthopedic Surgery, New York University, New York, USA, 2 Orthopedic Surgery, Long Island Jewish Medical Center, USA
Introduction and Objective: Patella Alta in Down and Larsen syndromes is frequently associated with lateral patellar malalignment. The patella may tilt and dislocate with knee flexion, significantly compromising ambulation. A technique to surgically realign the infrapatellar ligament in the immature child that preserves the integrity of the proximal tibial physis, is presented.
Materials and Methods: Surgical realignment was performed on 28 knees in 16 patients with a mean age of 10.8 years. Ten patients had Down’s syndrome, five Larsen’s syndrome and one, cerebral palsy. Approached laterally, the infrapatellar tendon was freed to the cartilaginous tibial tubercle. It was then meticulously dissected off the cartilage, deliberately leaving a thin layer of tendon covering the physis. The dissection was extended distally, lifting a long strip of periosteum in continuity with the tendon. Periosteum was raised medially and distal to the tibial tubercle. The infrapatellar ligament and periosteal extension was placed correctly distally and medially and secured with a stout suture that passed through a tibial drill hole. The previously elevated medial periosteal flap was then sutured over the repositioned infrapatellar ligament.
Results: Patella stability, good quadriceps power and knee function was achieved in all patients. Follow-up was a minimum of five years, all to beyond skeletal maturity. None had any proximal tibial growth plate disturbance.
Conclusions: This technique safely realigns the infrapatellar tendon before maturity of the proximal tibial growth plate. It enables early effective treatment of young children with elevated, lateral or dislocating patellae.
Clubfoot
OP-061
Gait analysis characteristics in clubfoot relapse
Rachel Goldstein1,2, Melissa Bent1, Maia Hauschild1, Adriana Conrad-Forrest1, Susan Rethlefsen1, Tishya Wren1,2, Bob Kay1,2
1Children’s Orthopaedic Center, Children’s Hospital, Los Angeles, USA, 2Keck School of Medicine,
University of Southern California Los Angeles, USA
Introduction and Objective: Research has shown that surgically treated clubfeet have poorer gait kinematics and kinetics than those treated with the Ponseti method. Little research has focused on late clubfoot relapse comparing the Ponseti method to joint sparing and joint invasive surgeries. Our purpose was to compare gait characteristics of children with late clubfoot relapse (≥ 5 years of age) following treatment with the Ponseti method compared to intra-articular (posteromedial release) and extra-articular (joint sparing procedures) surgery.
Materials and Methods: Retrospective review was conducted at a tertiary children’s hospital of all patients with a diagnosis of idiopathic clubfoot ≥ 5 years old who underwent gait analysis for clubfoot relapse between 2001 to 2021. Gait data including passive range of motion, strength, gait kinematics and kinetics were compared among 3 groups based on prior clubfoot treatment: 1) Ponseti casting, 2) Extra-articular (EA) and 3) Intra-articular (IA) surgery using ANOVA and Fisher’s exact test.
Results: 88 subjects (137 feet) were included (49 bilateral). The largest group of relapsed clubfeet was in the IA group (52%), followed by the Ponseti (35%) and EA (13%) groups. Average age when presenting with relapse was younger for the Ponseti group (8.0 years) compared with the IA (9.3 years) and EA (10.8 years) groups (p = 0.04, Table 1). The IA group had greater dorsiflexion passive range of motion than the other two groups (p < 0.04), greater plantarflexion and inversion weakness (p < 0.001), greater dorsiflexion during the stance phase of gait, and lower maximum plantarflexor moment and power production at push-off (p < 0.03).
Conclusions: Late relapse can occur after all types of clubfoot correction. Consistent with existing literature, patients who have undergone posteromedial release surgery have significantly greater plantarflexor weakness resulting in poorer plantarflexor moment and power production during gait. Next steps will include characterization of outcomes following treatment for late clubfoot relapse.
Clubfoot
OP-062
Weight-bearing computed tomography of the foot and ankle in the pediatric population
Derek Kelly1, Hayden Holbrook1, Alexander Bowers2, Karim Mahmoud1, Benjamin Sheffer1
1Campbell Clinic, Germantown, USA, 2University of Tennessee Health Science Center, College of Medicine, Memphis, USA
Introduction and Objective: Newer cone-beam computed tomography (CT) technology has grown in popularity for evaluation of foot and ankle pathology in the weight bearing (WB) position. Many studies have demonstrated its benefits within the adult population, but there is a paucity of information on its use in the pediatric literature. The purpose of this study was to describe the indications and clinical findings of weight bearing CTs (WBCT) within a pediatric population.
Materials and Methods: A retrospective cohort of 68 patients (86 extremities) who underwent WBCT for a variety of conditions were compared with 48 patients (59 extremities) who underwent traditional supine non weight bearing (NWB) CTs. Clinical indications, demographic data, radiation doses, and cost were obtained from the medical record.
Results: The most common indications for obtaining a WBCT and NWBCT in our study were fracture, tarsal coalition, and Lisfranc injury. The average WBCT radiation dose was 0.63 mGy for patients weighing < 100 lbs and 1.1 mGy for patients weighing > 100 lbs. The average NWBCT radiation dose was 7.92 mGy for patients weighing < 100 lbs and 10.37 mGy for patients weighing > 100 lbs. There was a significant reduction in radiation dose for all patients who had WBCT (p -values < 0.0001 vs. p = 0.002). The average reimbursement for NWBCT was $505 for unilateral studies and $1,451 for bilateral studies. The average reimbursement for the WBCT was $345 for unilateral studies and $635 for bilateral studies.
Conclusions: WBCT is a new modality for studying complex foot and ankle pathoanatomy in the pediatric population with reduced radiation exposure and reduced cost. This modality offers three-dimensional evaluation of pediatric and adolescent foot and ankle deformities or trauma in a position of function.
Clubfoot
OP-063
The outcomes of congenital talipes equinovarus (CTEV): A core outcome set (COS) for research and treatment
Yael Gelfer1 2, Donato Giuseppe Leo3, Aisling Russell3, Daniel Perry4, Anna Bridgens3, Deborah Eastwood5
1Paediatric Orthopaedics, St Georges Hospital, London, United Kingdom, 2St Georges University of London, United Kingdom, 3St Georges Hospital, London, United Kingdom, 4Alder Hey Children’s Hospital, Liverpool, United Kingdom, 5Great Ormond Street Hospital, London, United Kingdom
Introduction and Objective: CTEV management following the initial Ponseti correction is controversial and variable. Outcome reporting and follow up time differ, resulting in a wide range of reported recurrence and surgery rates. We aim to identify the basic fundamental outcomes to be used in clinical practice and research in Idiopathic CTEV using the COMET (Core Outcome Measures in Effectiveness Trials) guidelines.
Materials and Methods: A list of outcome tools and measures was obtained through a systematic review. Further outcomes were collected from families through a questionnaire and interview process. The combined list was rated for importance in a two round Delphi process that included an international group of surgeons, physiotherapists, nurses and families. Outcomes that reached no consensus during the Delphi process were further discussed and scored for inclusion/exclusion in a final consensus meeting involving international stakeholder representatives of practitioners, families and charities.
Results: Twenty outcome measures and 16 outcome tools were identified in the systematic review. Two more outcome were added from the questionnaires and three were added from round one Delphi. Twenty-four outcomes reached consensus in during the Delphi, and two outcomes reached consensus out. Nineteen outcomes reached no consensus and were discussed and voted upon in the final meeting. Twenty-one participants attended the final consensus meeting including a wide diversity of practitioners, family representative and a chair. Nineteen outcomes were discussed and voted upon; five reached consensus in and 14 reached consensus out. The final COS includes nine individual outcomes and two outcome scores. It incorporates static and dynamic clinical findings and PROMs. This includes a total of 31 outcome parameters to be collected after a minimum follow up of five years.
Conclusions: Defining a COS is a fundamental step in CTEV decision-making in treatment. It will allow meaningful research and a better clinical management of CTEV.
Clubfoot
OP-064
Obesity increases risk for surgical site infections and wound dehiscence after pediatric foot surgery: A retrospective cohort review using the NSQIP-pediatric database
Farzam Farahani1,2, Joel Rodriguez1,2, Dane Wukich2, Jacob Zide1,3, Anthony Riccio1
1Texas Scottish Rite Hospital for Children, Dallas, USA, 2University of Texas Southwestern Medical Center, Dallas, USA, 3Baylor Scott & White Hospital, Dallas, USA
Introduction and Objective: This study aims to compare postoperative complications between obese and non-obese pediatric patients undergoing surgical foot deformity correction.
Materials and Methods: Pediatric patients who had undergone operative foot deformity correction were retrospectively identified by cross-referencing reconstructive foot-specific CPT codes with ICD-9/ICD-10 deformity codes using the American College of Surgeons 2012-2017 Pediatric National Surgical Quality Improvement (ACS-NSQIP-Pediatric) database. Patients were stratified into normal weight and obese cohorts based upon Center for Disease Control BMI-to-age growth charts. Univariate and multivariate analyses were then performed to assess for obesity as an independent predictor of post-operative complications.
Results: Of the 3,924 patients identified, 1,063 (27.1%) were obese. Obese patients were older (10.31 years vs. 9.33 years; p = 0.007), more often male (64.7% vs 58.7%; p = 0.001), and taller (56.3in vs 51.3in; p < 0.001) than normal weight patients. There were no differences in pre-operative comorbidities between the normal weight and obese cohorts. Obese patients had a higher overall post-operative complication rate compared to normal weight patients (3.01% vs 1.32%; p = 0.001). Univariate analysis revealed a significantly higher rate of wound dehiscence in obese patients (1.41% vs 0.59%; p = 0.027) as well as a higher surgical site infection (SSI) rate that trended towards, but did not reach, statistical significance (1.32% vs. 0.59%; p = 0.061). No differences were noted in unplanned readmissions (1.03% vs 0.9%; p = 0.968) or unplanned reoperations (1.03% vs. 0.45%; p = 0.118) within 30 days of surgery between the two groups. In multivariate analysis, obesity was found to be an independent predictor of both wound dehiscence (adjusted OR = 2.16; 95%CI = 1.05-4.50; p = 0.037) and SSI (adjusted OR = 3.03; 95%CI = 1.39-6.61; p = 0.005).
Conclusions: Obese children undergoing foot deformity correction surgery had higher overall complication rates than normal weight patients. Obesity was found to be an independent predictor of both wound dehiscence and SSI within 30 days of surgery.
Clubfoot
OP-065
Incidence and outcomes of leg length discrepancy in patients with idiopathic clubfoot deformity
Maryse Bouchard1, Abdullah Addar1,2
1 Orthopaedic Surgery, The Hospital for Sick Children, Toronto, Canada, 2King Saud University, Riyadh, Saudi Arabia
Introduction and Objective: Evaluate the incidence and outcomes of idiopathic clubfoot patients with limb-length discrepancies (LLD).
Materials and Methods: Retrospective cohort study of idiopathic clubfoot in a clubfoot registry. Patients with LLD ≥ 0.5 cm (LLD+) were compared to those with no LLD (LLD-). LLD was determined by clinical examination, and radiographs available. Exclusion criteria included non-idiopathic clubfoot, < 2 year follow up, and incomplete records. Descriptive and multivariate analysis was performed
Results: 301 patients met inclusion criteria, 28 patients (9.3%) had LLD; 24 unilateral and 4 bilateral. The incidence of LLD was 15.9% and 2.65% in unilateral and bilateral clubfoot. The mean LLD was 1.31 cm (SD 0.94) for the entire cohort, 1.38 cm (SD 0.96) in unilateral clubfoot and 0.875 cm (SD 0.75) in bilateral patients. The number of casts in LLD+ unilateral clubfoot patients was higher than LLD- unilateral patients (9.5 vs. 6.8 casts; p = 0.015). The surgical rate was higher in LLD+ patients for entire and bilateral cohorts (46.6% vs. 14.74%; p = 0.01, RR = 2.1, vs. 80% vs. 22.6%; p = 0.013, RR = 3.5) ; the rate of surgery in unilateral LLD+ vs LLD- patients was not significant (37.5% vs 20.5%; p = 0.11), LLD+ unilateral clubfoot patients more frequently required open tendo-Achilles lengthening (TAL) (25% vs. 4%; p = 0.002) and a higher occurrence of relapse (41.6% vs. 15.8%; p = 0.009, RR = 2.9). There was no difference in relapse rate when examining the entire cohort or bilateral patients. One patient with unilateral clubfoot (3.6%) required limb equalization (proximal tibial epiphysiodesis). No correlation between LLD and Pirani score
Conclusions: LLD was present in 9.3% of idiopathic clubfoot; majority < 2 cm. Patients with unilateral clubfoot and LLD, have a higher risk of open TAL and relapse. Assessment of LLD should be routinely performed in clubfoot patients. Limb length equalization in clubfoot even with small differences may improve outcomes. Further studies are needed.
Clubfoot
OP-066
Sport ability during walking age in children with clubfeet treated with Ponseti method: A case series
Gianluca Testa1, Andrea Vescio1, Alessia Caldaci1, Marco Sapienza1, Annalisa Culmone1, Vito Pavone1
1Dipartimento di Chirurgia Generale e Specialità Medico-Chirurgiche, AOU Policlinico Rodolico - San Marco, Catania, Italy
Introduction and Objective: The Ponseti method (PM) of manipulative treatment for congenital talipes equinovarus (CTEV) or clubfoot became widely adopted by pediatric orthopedic surgeons at the beginning of the mid-1990s with reports of long-term successful outcomes. Sports are crucial for children’s development and for learning good behavior. The main objective of this study was to evaluate the sports activity levels in children with CTEV managed by PM. The secondary aim was to evaluate whether any differences in sport activity performance exist between male and female patients with unilateral or bilateral CTEV.
Materials and Methods: Between 2010 and 2020, 79 children with CTEV were treated with PM in our Institution. Non-idiopathic CTEV; age < 3 years; no participation in sports activities; and follow-up < 2 years were the exclusion criteria. Initial Pirani Score (PS) and number of casts needed (NCN) were recorded. The patients were clinically evaluated according to the Clubfoot Assessment Protocol, American Orthopedic Foot and Ankle Society, Ankle-Hindfoot score, the Foot and Ankle Disability Index (CAP, AOFAS, and FADI, respectively), and FADI Sport scores.
Results: A total of 44 feet CTEVs treated by the PM were included in the study. The overall mean CAP, AOFAS, FADI, and FADI Sport scores were 97.5 ± 6.4 (range 68.75-100), 97.5 ± 5.8 (range 73.00-100), 99.9 ± 0.6 (range 97.1-100), and 100, respectively. No statistical correlation between the scores and PS or NCN (p > 0.05) was found. Gender and bilaterality did not affect outcome (p > 0.05)
Conclusions: The data confirmed good-to-excellent outcomes in children with CTEV managed by PM. No limitations in sport performance or activity and correlation with initial CTEV severity and number of needed casts could be observed. In particular, male and female patients and patients with unilateral or bilateral involvement performed equally well.
Clubfoot
OP-067
The impact of socio-economic factors on drop-out, relapse and non-compliance during Ponseti treatment in low- and middle-income countries: A scoping review
Manon Pigeolet1 2, Anchelo Vital1, Hassan Ali Daoud1, Carol Mita3, Blake Alkire1, Daniel Corlew1
1Department of Global Health and Social Medicine, Harvard Medical School, The Program in Global Surgery and Social Change, Boston, USA, 2Université Libre De Bruxelles / Campus Érasme, Anderlecht, Belgium, 3Harvard Medical School, Countway Library, Boston, USA
Introduction and Objective: Idiopathic clubfoot is the most common musculoskeletal congenital disease in need of intensive orthopedic treatment. About 175,000 children or 1/1000 alive born infants are born annually with clubfoot worldwide. The Ponseti treatment is considered the gold standard for clubfoot globally. The aim of this scoping review is to assess and evaluate the impact of socio-economic factors on the presence of drop-out, relapse or non-compliance during Ponseti treatment in low and middle-income countries (LMICs).
Materials and Methods: All articles describing an association between one or more socio-economic factors and one or more adverse outcomes during the Ponseti treatment in an LMIC were considered for inclusion. Studies were identified by searching Medline/PubMed, Embase, Global Health and Global Index Medicus. Data extraction was done using Covidence extraction 2.0 by 2 independent reviewers.
Results: A total of 306 references were retrieved from the database searches, 54 abstracts were retained for full-text review, of which 17 studies were included in the final review. We identified several socio-economic factors and grouped them together in 4 larger themes: poverty and physical accessibility of clubfoot clinics, presence of support systems, educational level of the parents and household-level factors and cultural norms. Reduced access to care for girls was considered an important risk factor in 2 studies from South Asia and in 1 study from the Caribbean. Lack of family and community support seems to be an issue raised more often in studies from Eastern Africa.
Conclusions: The identified factors are very similar to the socio-economic factors identified in studies looking at the barriers parents and children face when seeking care initially. Poverty was identified as a cross-cutting risk factor in all 4 domains and the most important socio-economic risk factor based on this review, reconfirming poverty eradication as the challenge for the 21st century.
Clubfoot
OP-068
Anterior distal epiphysiodesis as treatment of recurrent equinus deformity in Ponseti treated clubfoot patients
Arnold Besselaar1, Isabelle van Tilburg1, Tessa van de Kerkhof1, Benedicte Vanwanseele2 3, Lianne Grin2 3, Saskia Wijnands1 23, Marieke van der Steen, 1 4
1Department of Orthopaedic Surgery & Trauma, Máxima MC, Veldhoven, The Netherlands, 2Fontys University of Applied Sciences, Eindhoven, The Netherlands, 3Human Movement Biomechanics Research Group, Faculty of Kinesiology and Rehabilitation Sciences, KU Leuven, Leuven, Belgium, 4Department of Orthopaedic Surgery & Trauma, Catharina Hospital, Eindhoven, The Netherlands
Introduction and Objective: Since the introduction of the Ponseti method as preferred treatment for idiopathic clubfoot, the amount of persistent or relapse clubfeet reduced. However, a relapse of clubfoot still occurs in 11-48% of the clubfoot patients. Anterior distal tibial epiphysiodesis (ADTE) showed inconsistent clinical results as treatment for recurrent equinus deformity in surgically treated clubfoot patients. In the current study we investigated the effect of ADTE by means of temporary hemi-epifysiodesis as correction of a recurrent equinus deformity in Ponseti treated clubfoot patients.
Materials and Methods: Idiopathic clubfoot patients aged between 4 and 12 years initially treated with the Ponseti method, planned for ADTE between 2015 and 2019 were assessed preoperatively and when indicated for 8-plate removal. A senior orthopaedic surgeon specialized in clubfoot treatment determined passive dorsiflexion. Furthermore, on standardized lateral radiographs the anterior distal tibial angle (ADTA) was measured. In addition, in one patient extended three-dimensional gait analyses were performed before treatment and after indication for 8-plate removal.
Results: The median treatment duration of 21 feet (14 patients, 50% male, 7.3 years) was 21 (range: 6.0-32) months. The preoperative ankle dorsiflexion significantly improved from 0° (range: -20-10 degrees) to 5° (range: 0-15 degrees) The ADTA significantly decreased from 82.6° [95%CI: 79.8-85.3 degrees] to 74.2° [95%CI: 69.4-79.0 degrees]. No wound or neurovascular complications were observed. Extended gait analyses of one patient (female, 9 years) showed limited ankle dorsiflexion and increased intoeing pre-treatment. Ankle kinematics improved post-treatment, both ankle plantar-/dorsiflexion and intoeing fell within the normal range of healthy controls.
Conclusions: ADTE seems to be a safe and effective treatment of recurrent equinus deformity in Ponseti treated clubfoot patients with increased ADTA. This dataset will be extended with additional patients, clinical and radiological assessments at least one year after 8-plate removal to determine if results last.
Foot Congenital
OP-069
Resection of calcaneo navicular coalition: Arthroscopy or open approach?
Corin Boris1, Jérôme Sales de Gauzy1, Franck Accadbled1
1CHU de Toulouse, France
Introduction and Objective: Calcaneonavicular coalition (CC) accounts for more than half of all tarsal coalitions. Resection of CC by an open approach (OA) is the standard treatment and provides satisfactory long-term results. Treatment of CC by an arthroscopic approach (AA) appears promising. The objective of our study was to compare the clinical outcomes of CC resection by OA vs AA.
Materials and Methods: A retrospective cohort study was conducted to evaluate 127 patients who underwent a resection of CC from 2009 to 2017. The cohort was divided into two groups according to whether an Arthroscopic (AA), or an Open (OA) approach was used. Demographics, operative parameters, and clinical outcomes (FAAM score, subjective score, and global ankle estimation) were assessed. The effect of surgical experience in AA on the treatment and clinical outcome was assessed.
Results: AA was used for 82 patients and OA for 46 patients. Treatment with AA resulted in a shorter hospital stay (2.6 ± 0.6 days vs. 3.0 ± 0.7; p = 0.02) and a longer operative time (24.5 ± 8.1 minutes vs. 20.5 ± 4.2; p < 0.01) than with OA. The FAAM Sports subscale scored significantly higher in the AA group (90.9 vs 77.3; p = 0.003). Revision rate was significantly higher in the AA group [12 (15%) ] vs the OA group (1 (2%) ) (p = 0.024). Persistent symptoms (n = 12) were the main reason for revision. AA was correlated with a shorter hospital stay (β = -0.02; p < 0.005) but did not influence the clinical outcome.
Conclusions: Arthroscopic treatment of CC provides equivalent functional results to treatment by OA. However, revision rate related to the persistence of symptoms is higher than using OA.
Foot Congenital
OP-070
Functional results of surgical treatment of tarsal coalitions: Arthroscopic resection versus open resection
João Cabral1, André Carvalho1, Ines Balacó1, Marcos Carvalho1, Oliana Madeira Tarquini1, Pedro Sá Cardoso1, Tah Ling1, Cristina Alves1
1Department of Pediatric Orthopaedics, Hospital Pediátrico - CHUC, EPE, Coimbra, Portugal
Introduction and Objective: Tarsal coalitions can cause significant foot and ankle pain, as well as deformity and loss of function. About 90% of symptomatic tarsal coalitions are calcaneonavicular or talocalcaneal and many require surgical treatment .The aim of this study is to compare the functional results of surgical resection of talocalcaneal and calcaneonavicular tarsal coalitions by open and arthroscopic surgery.
Materials and Methods: A retrospective study was carried out, including patients operated on tarsal coalitions in an institution, period 2005-2021.We describe the surgical techniques used and evaluate patients regarding coalition composition, laterality, follow-up and functional results (Foot and Ankle Outcome Score-FAOS).
Results: Forty-three patients,9 talocalcaneal coalitions and 35 calcaneonavicular coalitions, were included. In the group of patients with talocalcaneal coalitions, the age at the time of surgery was 14.22 ± 1.70 years. Female gender predominated (56%) and fibrocartilage bars (78%). The FAOS score was 87.50 ± 7.78 in patients undergoing open resection and 89.29 ± 8.77 in patients undergoing arthroscopic resection (p > 0.05 [p = 0.804]).
In the group of patients with calcaneonavicular coalitions, the age at the time of surgery was 13.80 ± 2.04 years. Male patients (51%) and bone coalitions (51%) predominated. The FAOS score was 88.65 ± 6.24 in patients undergoing open resection and 92.14 ± 6.69 in patients undergoing arthroscopic resection (p > 0.05). Follow-up time was shorter in patients undergoing arthroscopic resection in both types of coalitions and, to date, no relapses have been observed with this procedure. Open procedures resulted in 3 recurrences (2 calcaneonavicular, 1 subtalar).
Conclusions: Arthroscopic treatment of tarsal coalitions is effective and allows functional results similar to those obtained with open resections, with the benefits of a mini-invasive procedure, with less surgical aggressiveness and immediate mobilization of the foot in the postoperative period, without the need for plastered immobilization. The arthroscopic technique is a good option for treating tarsal coalitions.
Foot Congenital
OP-071
Health related quality of life in achondroplastic patients after global limb lengthening surgery
1Hospital Universitari Dexeus - Grupo Quirónsalud, ICATME, Barcelona, Spain, 2Biostats LLC, New York, USA
Objective: Though there are many references on limb lengthening in achondroplasia, no data on health-related quality of life has been published so far. The aim of our study was to explore the potential relationship between limb lengthening outcomes and the quality of life of achondroplasia patients.
Methods: A case series of 35 patients with a genetically confirmed diagnosis of achondroplasia undergoing surgical limb elongation (humeri, femurs and tibiae) was analyzed, including follow-up data collected up to 3 year of surgery completion. Mean (SD) age at first surgery was 12.3 (3.1) years and mean (SD) pre-procedure height was 112.3 (8.8) cm. Descriptive statistics were calculated for demographics, SF-36 individual response variables and subscale domains including Total SF-36 total score. Health status was assessed with SF-36 version 2. Historical controls from the Norwegian resource center for rare disorders (N = 44) were used in the comparison. Mean values across eight SF-36 sub-scales (Mental Health, Role Emotional, Social Functioning, Vitality, General Health, Bodily Pain, Physical Functioning, Role Physical) were compared with historical controls using hypothesis testing and one sample T-tests. All tests were two-sided, alpha was set to 0.05, and null hypothesis corresponded to each sub-scales’ mean historical control value. All variables in the sample were normally distributed. Correlations between height and SF36 variables, including Total SF Score, Vitality, Social and Physical Function, were also performed.
Results: Mean (SD) change in height was 37.8 (± 8.6) cm, mean (SD) height post-surgery was 150 (5.1) cm. Patients who underwent limb lengthening surgery reported statistically significant improvements (p = < 0.0001) across all SF-36 sub-scales when compared to the mean historical control values. Positive correlations were also found between height increase and SF36 sub-scales.
Conclusion: Global limb lengthening in achondroplasia patients performed according to our site protocol resulted in significant improvements of health-related quality of life according to the SF-36 questionnaire.
Foot Congenital
OP-072
The fate of bent telescopic rods in children with osteogenesis imperfecta: Do all bent rods need to be revised?
David Fralinger1, Denver Burton2, Kenneth Rogers1, Richard Kruse1, Jeanne Franzone1
1Nemours Alfred I. duPont Hospital for Children, Wilmington, USA,2Georgetown University, Washington, USA
Introduction and Objective: Osteogenesis Imperfecta (OI) is a genetic disorder characterized by frequent fractures and deformity. Realignment and intramedullary telescopic rodding can prevent fractures and correct deformity. Rod bending is a complication of telescopic rods, however, the fate of bent telescopic rods has not been reported.
Materials and Methods: Patients with OI who underwent lower extremity telescopic rod placement with at least one-year follow-up were identified. Bent rods were identified and we collected location and angle of bend, subsequent telescoping, refracture, increasing angulation of bend and revision.
Results: 168 telescopic rods in 43 patients were identified. 46 rods (27.4%) bent during follow-up, with average angulation of 7.3° (range 1-24°). 15.7% of rods in patients with severe OI bent compared with 35.7% in non-severe OI (p = 0.003). The proportion of bent rods was different between independent and non-independent ambulators (34.1%, 20.5%; p = 0.035). 27 bent rods (59%) were revised; 12 (26%) were revised immediately (within 90 days). The angulation of rods revised immediately was significantly higher than rods not immediately revised (14.6°, 4.3°, p < 0.001). Of the 34 bent rods not immediately revised, the average time to revision or final follow-up was 29.1 months. 25 rods (73.5%) continued to telescope, 14 (41%) increased in angulation (average 3.2°)
and 10 bones (29%) refractured: 5 nondisplaced fractures, 4 with increased angulation without loss of fixation, and one pilon fracture; none prompted immediate rod revision. Two bones had multiple refractures.
Conclusions: Bending is a common complication of telescopic rods in patients with OI. It is more common in independent ambulators and patients with non-severe OI, possibly due to the increased demand placed on the rods. Rods with a small bend and maintained fixation can telescope and need not be immediately revised. About one third will refracture, but fixation was maintained and refractures did not require immediate revision
Foot Congenital
OP-073
What are the factors predisposing to failure of Fassier-Duval rodding in children with osteogenesis imperfecta?
Bartosz Musielak1, Łukasz Woźniak1, Jerzy Sułko2, Artur Oberc3, Marek Jozwiak1
1Department of Paediatric Orthopaedics and Traumatology, Wiktor Dega Hospital, Poznań University of Medical Sciences, Poznan, Poland, 2Collegium Medicum, Jagiellonian University, Cracow, Poland, Department of Pediatric Surgery, Cracow, Poland, 3University Children`s Hospital, Cracow, Poland, Poland
Introduction and Objective: There are number of factors reported in the literature, predisposing to the failure of Fassier-Duval rods. However, the reports are inconsistent. Thus the purpose of this study was to present the most common complications of Fassier-Duval rodding and to identify factors predisposing to treatment failure.
Materials and Methods: We assessed the total number of complications clinically and radiographically in 58 segments rodded in 19 patients with osteogenesis imperfecta (type III). The median follow-up time in this cohort was 4.4 years. The possible predisposing factors leading to failure were assessed using the Mann-Whitney U test. Additionally, we evaluated the cut-off age for the increased rate of complications using the Youden index. A p < 0.05 was considered significant.
Results: The total number of complications reached 44.8%. The most common complications included: migration of the male or female implant, followed by bone fracture with bending of the rod, and rotational deformities. Significant differences in patients’ ages at the time of surgery were found between the group with and without complications (p = 0.04), while sex, segment treated, preceding surgeries, length of FU, and length of bisphosphonate treatment were not significant. There was also a tendency (not significant) towards higher complication rates in small diameter rods (3,2mm). The Youden index showed that the risk of complications rose significantly in patients treated when younger than 5.5 years of age (p < 0.05).
Conclusions: This series displays that the complications observed were comparable with existing literature, however there was observed increase in the number of side effects in younger patients (below age 5) and in patients in whom the size of the rod was smaller.
Neuromuscular 1
OP-074
Development of hip displacement in children with cerebral palsy: A longitudinal register study of 1045 children
Philippe Wagner1, Gunnar Hägglund2
1Västerås, Centre for Clinical Research, Västerås, Sweden, 2Lund University, Orthopedics, Lund, Sweden
Introduction and Objective: Hip surveillance in children with cerebral palsy (CP) includes repeated radiographic hip examination and measurement of the hip migration percentage (MP). We analyzed the early development of the MP in hips operated on to prevent hip dislocation and hips stabilized without surgery.
Materials and Methods: From the Swedish Surveillance Programme for CP, 5899 radiographic measurements from 1045 children in GMFCS level III-V born in 1996-2011 were analyzed. For children operated on to prevent hip dislocation, measurements up to the most recent preoperative radiograph were included. The hip with highest MP was analyzed for each child. A mixed-effects model was used to estimate the development of the MP at each age for each child and the population mean.
Results: In the 702 children who did not undergo preventive surgery, the mean MP increased with decreasing velocity up to age 6 years. Here it reached 24.3% (95% confidence interval [CI] 23.5-25.1), with a velocity of 0.3%/year (95% confidence interval [CI] 0.0-0.5), remaining approximately stable up to age 12 years. In the 343 children who underwent preventive surgery, the mean MP increased with an increasing velocity from a mean of 29.9% (95% CI 27.4-32.3) 3 years before the operation.
Conclusions: An increasing rate of hip displacement in hips with an MP > 24% indicates the need for preventive surgery. Hips stabilized without preventive surgery had a decreasing displacement rate and were usually stabilized with an MP < 30% at age 6 years.
Neuromuscular 2
OP-075
Hip development after surgery to prevent hip dislocation in children with cerebral palsy: A longitudinal register study of 252 children
Philippe Wagner1, Gunnar Hägglund2
1Västerås, Centre for Clinical Research, Västerås, Sweden, 2Lund University, Orthopedics, Lund, Sweden
Introduction and Objective: Operative treatment of hip displacement in cerebral palsy (CP) includes adductor-psoas lengthening (APL) or varus derotation osteotomy (VDRO) of the proximal femur, sometimes combined with pelvic osteotomy. After both operations, there is a significant risk of relapse and need for reoperation. We used the migration percentage (MP) to compare the development of hip displacement after APL and VDRO.
Materials and Methods: All reported MP measurements for children treated with APL or VDRO and followed ≥3 years were obtained from the Swedish Surveillance Programme for CP. In children treated with bilateral surgery, the hip with the highest preoperative MP was analyzed. A mixed-effects model was used to estimate the development of MP with age for each child and the population mean.
Results: The 104 hips that underwent APL without reoperation showed a gradually reduced MP postoperatively. The 54 hips that underwent a 2nd surgery with APL or VDRO because of redisplacement had a higher displacement rate preoperatively and continued displacement postoperatively but at a slower rate. The 94 hips that underwent VDRO showed an instantaneous decrease in MP postoperatively followed by a rate of increasing displacement. The 15 hips that underwent a 2nd VDRO had a higher rate of displacement both pre- and postoperatively.
Conclusions: After APL, hip displacement either decreases or continues to increase but at a slower rate. After VDRO, the MP decreases momentarily but then gradually increases. The risk of reoperation is higher in children with a high preoperative displacement velocity and a high preoperative MP.
Neuromuscular 2
OP-076
The incidence of AVN after hip containment surgery in children with cerebral palsy
Jeremy Bauer1, Ellen Raney1, Dennis Roy1
1Shriners Hospitals for Children, Portland, USA
Introduction and Objective: The purpose of this study was to determine the rate of avascular necrosis (AVN) after hip reconstruction surgery in children with cerebral palsy (CP) and to identify any risk factors that contribute to the development of AVN.
Materials and Methods: An institutional review board (IRB) approved retrospective review was conducted on children with CP who underwent hip containment surgery. Radiographs were evaluated at three time points. The Reimer’s migration percentage, neck shaft angle, epiphyseal shaft angle, acetabular index, and acetabular angle were measured. The presence of AVN was evaluated and graded by the Bucholz/Ogden and the Kalamchi/MacEwen classification systems by three fellowship trained pediatric surgeons. Statistical analysis was performed to identify risk factors that may be associated with the development of AVN.
Results: A total of 181 children with CP who underwent hip containment surgery were reviewed. 35 patients underwent both pelvic and femoral procedures, 39 patients had only femoral procedures, 56 had femoral and soft tissue and 51 patients had pelvic, femoral and soft tissue procedures. The rate of AVN was 23.8% (43/181). Open reduction, previous surgery, age at surgery, EBL and preoperative Reimers migration percentage only explained 8.5% of the variance of AVN development in children undergoing surgery, with only EBL contributing significantly to the model. The ICC for the Bucholz/Ogden classification was.339-.538 (Left and Right) and the ICC for the Kalamachi/MacEwen classification was.416-.570 (Left and Right) showing only fair to good agreement amongst these measures.
Conclusions: The current classification systems available for the assessment of AVN may not capture the complexity of the hip in children with CP. While several predictors of AVN development have been proposed, only EBL significantly contributed to model suggesting that better soft tissue handling and careful hemostasis during surgery may be important in preventing AVN.
Neuromuscular 1
OP-077
Practice variation and factors influencing indications for interventions for hip displacement in non-ambulant children with cerebral palsy
Max Mifsud1, Unni G. Narayanan1, U. Givon, K. Graham, Marek Jozwiak, Kishore Mulpuri, Benjamin Shore, T. Theologis, W. Schrader, The CHOP Research Group
1SickKids, Orthopaedics, Canada
Introduction and Objective: There are many treatment strategies for hip displacement in non-ambulant children with CP, with variation in indications, timing and choice of procedures. CHOP is an international prospective cohort study comparing different strategies. This paper quantifies practice variation among CHOP surgeons and explores factors influencing decision-making.
Materials and Methods: 71 case vignettes were presented from CHOP database capturing spectrum of age, GMFCS level, Migration Percentage (MP), uni/bilateral involvement, acetabular dysplasia, femoral head-shape, ROM (R1/R2), presence of hip symptoms. 28 clinicians (mean 10 years CP practice) from 17 sites globally made recommendations blinded to others’ responses. Factors influencing decisions were analyzed using logistic regression.
Results: Cases were 6.9 years old (2-17.5yrs) ; MP 58% (0-100) ; 37/71 had symptoms. 40% chose watchful waiting for MP up to 50%, with others recommending botox (15%); soft-tissue releases (18%); or bone-reconstruction (27%). Decision to operate was influenced by symptoms. When MP > 50%, 95% recommend surgery, predominantly VDRO. Acetabuloplasty was added when children > 5 years with increasing dysplasia and MP. Wide variation in indications for open reduction, recommended by 40% to 60% of surgeons with increasing MP. Salvage was preferred for high-riding/irreducible dislocations (OR:23); severely dysplastic (OR:16), and symptomatic (OR:8.7).
Management recommendation based on age (left) and MP (right).
Conclusions: MP and patient symptoms are major drivers of surgical recommendations. However, treatment recommendations vary among experienced CP surgeons world-wide.
Neuromuscular 1
OP-078
Progression of hip displacement after triradiate cartilage closure in non-ambulatory cerebral palsy (CP): Who needs continued radiographic surveillance?
Ali Asma1, Armagan Can Ulusaloglu1, Michael W. Shrader1, Kenneth Rogers1, Freeman Miller1, Jason Howard1
1Nemours Children’s Hospital, Delaware, Wilmington, USA
Introduction and Objective: For CP, recommendations regarding the need for continued radiographic hip surveillance after skeletal maturity have been based on expert opinion. The objective of this study was to determine the prevalence and risk factors associated with progressive CP hip displacement after triradiate cartilage closure (TRC), a proxy for skeletal maturity.
Materials and Methods: Retrospective cohort. Patients with spastic non-ambulatory CP (GMFCS IV-V), minimum 4 yearly hip x-rays after age 10 years, and at least 1 x-ray after age 16 years, were included. Primary outcome was migration percentage (MP). Secondary outcomes included age at TRC closure, previous preventative (adductor releases) or reconstructive (femoral ± pelvic osteotomies) surger (ies), previous intrathecal baclofen (ITB), previous scoliosis surgery, and associated comorbidities. An “unsuccessful hip” was defined by MP progression to ≥ 50%, or requiring reconstructive surgery, after TRC closure. Statistical analyses included multivariate logistic regression and Kaplan Meier survivorship.
Results: 87 patients (174 hips) met the inclusion criteria, final follow-up 10.6 ± 2.2 years (4.5 ± 2.4 years after TRC closure). After TRC closure (mean age, 14.6 ± 1.7 years), 16.7% of hips progressed to an unsuccessful hip. In multivariate analysis, male gender (p = 0.024), higher first MP after TRC closure (p = 0.001), and no prior hip surgery (p = 0.004) were risk factors for an unsuccessful hip. Survivorship was higher for females (p = 0.03), prior reconstructive vs prior preventative (p = 0.004) or no surgery (p = 0.03). There was no difference in hip survival for pelvic osteotomy (p = 0.20). A first MP after TRC closure of ≥ 24.5% was associated with progression to an unsuccessful hip (ROC curve analysis, p < 0.001).
Conclusions: The risk factors for progression of CP hip displacement after TRC closure include male gender, only preventative or no prior hip surgery, and a higher MP. Patients with these risk factors and/or an MP ≥ 25% at TRC closure should have continued radiographic surveillance to detect late hip displacement.
Neuromuscular 1
OP-079
Femoral head deformity associated with hip displacement in cerebral palsy: Results at skeletal maturity
Armagan Can Ulusaloglu1, Ali Asma1, Michael W. Shrader1, Kenneth Rogers1, Freeman Miller1, Jason Howard1
1Nemours Children’s Hospital, Delaware, Wilmington, USA
Introduction and Objective: Maintaining femoral head shape (FHS) and acetabular sphericity are important goals to help prevent long-term osteoarthritis in CP hips. As acetabular morphology has been widely studied, our objective was to determine CP-FHS after triradiate cartilage (TRC) closure, a proxy for skeletal maturity, and the risk factors associated with residual deformity and osteoarthritis.
Materials and Methods: Retrospective cohort. Patients with CP (GMFCS IV-V), minimum 4 yearly hip x-rays after age 10y, and at least 1 x-ray after age 16y, were included. Primary outcome was FHS as described by Rutz, stratified as “less severe” (Rutz A-B) and “more severe” (Rutz C-D). Secondary outcomes included migration percentage (MP), age at TRC closure, previous reconstructive (femoral±pelvic osteotomies) surgery, previous intrathecal baclofen (ITB), Tönnis osteoarthritis grade, GMFCS level. Statistical analyses included chi-square analysis and multiple logistic regression.
Results: 87 patients (174 hips) met the inclusion criteria, with TRC closure at age 14.6y (SD:1.7y). At final follow-up of 10.6y (SD: 2.2y), 19.5% (34 hips), had a “more severe” FHS. From TRC closure to final follow-up, the frequencies of Rutz A decreased (p < 0.001), while Rutz C increased (p < 0.001). In multiple regression analysis, MP at TRC closure was the only significant risk factor associated with a “more severe” FHS at final follow-up (p = 0.03). ROC curve analysis determined an MP ≥ 18.5% to be associated with a “more severe” FHS at final follow-up (p < 0.009). FHS was not affected by reconstructive surgery, gender, GMFCS level, or ITB use. “Less severe” hips had lower Tönnis grades (0-1) compared to “more severe” hips (Tönnis grades 2-3) at final follow-up (p < 0.001).
Conclusions: FHS at skeletal maturity was not influenced by prior reconstructive surgery but was negatively affected when MP ≥ 18.5% at the time of TRC closure. The extent of residual femoral head deformity was correlated to the severity of osteoarthritis at final follow-up.
Neuromuscular 2
OP-080
Observational gait analysis in children with cerebral palsy using the Edinburgh Visual Gait Score (EVGS) and smartphone-based slow-motion video technology: A pilot study
Bhushan Sagade1, Alaric Aroojis1, Suresh Chand1
1Bai Jerbai Wadia Hospital for Children, India
Introduction and Objective: We conducted this study to describe and test the reliability of a protocol for performing quantitative Videographic Gait analysis (VGA) of children with cerebral palsy (CP) using hand-held smartphone camera, slow-motion video technology, motion analysis applications and Edinburgh Visual Gait Score (EVGS).
Materials and Methods: Thirty ambulatory children with spastic CP with a mean age of 7.25 years (Range: 4 - 14 years) (Gross Motor Function Classification System [GMFCS] I - III) were included. Bony prominences were marked on each lower limb and children were made to walk on an 8 X 4-meter-long walkway. Slow-motion videos were recorded on a handheld smartphone, with the videographer sitting on a chair, three metres from the subject. Three to five gait cycles were recorded in the sagittal and coronal planes. Seventeen parameters of EVGS were calculated on the smartphone with Hudl Technique application, by freezing the gait videos in appropriate phases of gait.
Results: Mean (range) of the scores for the Trunk, Pelvis, Hip, Knee, Ankle, Foot, and total were 1.18 (0 - 3), 0.68 (0 - 3), 1.1 (0 - 4), 3.95 (1.5 - 7.5), 1.87 (0 - 4), 4.13 (2 - 6.5), and 12.92 (7 - 21.5) respectively. The Mean (SD) scores for GMFCS I, II, and III were 8.5 (3.5), 10.73 (3.86) and 14.96 (4.2) respectively. The scores were significantly different between GMFCS II and III (p = 0.0003). Intra-observer and inter-observer reliability using percentage of complete agreement was 65 - 98.3% and 61.7 - 92.5% respectively, with kappa values ranging from 0.15 - 0.87. Reliability was more for distal limb segments as compared to proximal segments. The mean EVGS calculation time after completing video recording was 24.7 minutes (range:16 - 55 minutes).
Conclusions: We have described a simple yet reliable method for quantitative VGA of children with CP using smartphone-based slow-motion video technology and EVGS which can be performed by every clinician in outpatient clinic.
Neuromuscular 1
OP-081
Patients GMFCS III are more susceptible to gait deterioration after single-event multilevel surgery in cerebral palsy
Mauro César de Morais Filho1, Marcelo Fujino1, Francesco Blumetti1, Cátia Kawamura1, José Augusto Lopes1
1Hospital AACD, Gait Laboratory, São Paulo, Brazil
Introduction and Objective: The purpose of this study was to analyze the results of single-event multilevel surgery (SEMLS) in a group of cerebral palsy (CP) patients, identifying the factors related to better outcomes.
Materials and Methods: 258 patients with spastic diplegic CP, GMFCS I-III, who underwent SEMLS and had done pre and post-operative gait analyses were included in the study. The influence of age, gender, follow-up time, pre-operative Gait Deviation Index (GDI), previous surgeries, type of surgery (soft tissues or bony), GMFCS level and gait velocity on GDI change after surgical intervention was analyzed.
Results: The GDI changed from 51.3 to 58.4 after SEMLS (p < 0.001) in the studied group and the increase on GDI after SEMLS was greater (p = 0.003) in patients GMFCS I (10.6) and II (10.3) than GMFCS III (5.3). The improvement on GDI was higher (p = 0.004) in patients without previous orthopedic surgeries (9.1) than those underwent to surgical intervention previously (5.3). The GDI increased 6.2 in patients underwent to soft tissues plus bony procedures and 12.3 in those who received just soft tissue procedures (p < 0.001). Patients with improvement on GDI > 10 points had lower pre-operative GDI (46.15) than other groups (p < 0.001). In addition, patients with reduction on GDI after the intervention had lower pre-operative gait velocity than subjects with improvement > 10 points (p = 0. 01). Finally, a linear regression was performed and only GMFCS III influenced significantly the GDI change after SEMLS (p = 0.014). There was a negative effect of GMFCS III on GDI improvement after intervention.
Conclusions: Lower pre-operative GDI, higher baseline gait velocity, GMFCS levels I and II, patients without previous orthopedic surgeries and underwent to soft tissues procedures were related to better outcomes after SEMLS in the present study. On the other hand, patients GMFCS III were more susceptible to deteriorate after SEMLS.
Neuromuscular 1
OP-082
Patients and parents’ satisfaction and self-reported evaluation after single-event multilevel surgery in cerebral palsy
Mauro César de Morais Filho1, Francesco Blumetti1, Marcelo Fujino1, Daniela Maury Benavides1, Cátia Kawamura1, José Augusto Lopes1
1AACD Hospital and Rehabilitation Centre, Gait Laboratory, São Paulo, Brazil
Introduction and Objective: There is limited evidence regarding patients/parents’ satisfaction and self-reported evaluation after single-event multilevel surgery (SEMLS) in cerebral palsy (CP). The purpose of this study was to analyze the results of SEMLS, according the point of view of the patients and their families.
Materials and Methods: 258 spastic diplegic CP patients, GMFCS I-III, underwent SEMLS and with pre and post-operative gait analyses were included in the SEMLS group (SG). A second search was performed in the same database seeking for patients to compose the control group (CG), and 88 subjects, with at least two gait analyses and with no surgical intervention between tests, were identified. Demographic data, gait Deviation Index (GDI) and self-reported questionnaire applied as part of gait analysis were analyzed and the results were compared between groups.
Results: The GDI reduced from 59.6 to 57.9 in the CG and increased from 51.3 to 58.4 in the SG (p < 0.001). There was no change on patient’s physical abilities in CG and the number of patients who walk outside the home for community distances decreased after SEMLS (from 24.7% to 15.4%, p = 0.009), however when SG was divided according zones of GDI change, we observed an increase of these patients (from 12.8% to 25.2%, p = 0.008) in the group that had a GDI improvement > 5 points. According parents/patient’s satisfaction the highest scores of improvements were reported on mobility (50.2% improved/6.7% deteriorated), body image (49% improved/3.5% deteriorated) and independence (45.5% improved/4.3% deteriorated). 51.8% of the patients were extremely satisfied/satisfied while 3.9% were unsatisfied/extremely with the treatment results. According parents report, 60.8% were extremely satisfied/satisfied and 5.1% unsatisfied/extremely unsatisfied.
Conclusions: In the studied group, improvement of outdoor walking for community distances after SEMLS, reported in questionnaires by patients and their families, was observed only when GDI increase was greater than 5 points.
Neuromuscular 2
OP-083
Relation of the sural nerve and medial neurovascular bundle with the Achilles tendon in children with cerebral palsy treated by percutaneous Achilles lengthening
Ozan Ali Erdal1, Baris Gorgun1, Necip Selcuk Yontar2, Ali Ege Terzibasioglu3, Ilker Abdullah Sarikaya1, Muharrem Inan1
Introduction and Objective: A common treatment optiona for a short Achilles tendon in cerebral palsy is percutaneous Achilles tendon lengthening (PAL) using three hemi-sections. Because of proximity of neurovascular structures around the tendon, the sural nerve is under risk of injury at the site of the lateral incomplete cut and the medial neurovascular bundle is under injury risk at medial cuts. The aim of the study was to define anatomical relations of the sural nerve and medial neurovascular bundle to the Achilles tendon, and describe dangerous levels for injury with the help of magnetic resonance imaging.
Materials and Methods: Patients operated for PAL were called for MRI investigation of the sural nerve and medial neurovascular bundle with their anatomical relations to the Achilles tendon. 5 mm was taken as the limit of increased injury risk. Measurements were done on MRI images at each cm from the tendon insertion of the tendon on both sides, and at the level of the middle lateral hemi-section.
Results: 30 ankles operated mean 17,6 months before MRI were studied. On the medial side, the tibial nerve and the posterior tibial artery lied more than 5 mm away from the tendon at all levels. On the lateral side, the first four centimeters were relatively safe for the middle lateral cut, while increase in risk of sural nerve injury was detected in more proximal levels of the tendon. Overall, six out of 30 ankles had radiographically detectable sural nerve injury, with one complete cut.
Conclusions: The first four centimeters of the Achilles tendon on the lateral side was found to be relatively safe for the middle lateral directed cut, while whole tendon length was found to be safe for the first and the third hemi-sections of the PAL surgery using three hemi-sections in children with cerebral palsy.
Neuromuscular 2
OP-084
Long-term results equinus deformity treatment of the feet by Ulzibat and Strayer surgery methods in children with CP
Introduction and Objective: Equinus deformity of the feet the first deformitie that are noted in children with CP. The most common method is Z-achiloplasty and Strayer’s surgery, but the Ulzibat method is also quite common.
To conduct a retrospective comparative assessment of the effectiveness of the Ulzibat method and Strayer’s surgery in the long-term postoperative period.
Materials and Methods: 125 children with CP (71 boys and 54 girls), aged 4-10, who were identical in gender, age, type of pathology: according to the GMFCS: 43 patients (34.4 %) - Level II, 47 (37.6 %) - III, and 35 (28.0 %) - IV. The average follow - up period is 4.7 years (3 -6.5 years). Two groups: I - 49 children treated by Ulzibat technique (in 17 cases - once, and in 32 - from 2 to 4 times with interval of 6-12 months.); II - 76 children with Strayer surgery.
Results: The initial assessment of the condition of children with cerebral palsy after surgical treatment of Equinus deformity in both groups was carried out 3 months after the intervention. In both groups, a correction was achieved : in 1 group - 95.6% of cases, in 2 groups - 94.9%. However, according to GMFM-88 data, it can be noted that children of II group performed motor tasks in the standing position more clearly, and walking greater duration and confidence compared to I group. At 6 and 12 months after surgical treatment: in Group 1, in 48.98% of cases, clinical and radiological data of the feet significantly worsened, in Group 2-18.4%. 24 months - shows deterioration of verticalization and walking characteristics in Group 1.
Conclusions: The data obtained give grounds to assert that the Ulzibat technique carries a high risk of complications in the separated period, after 6-12 months, despite a good immediate result (3 months)
Neuromuscular 2
OP-085
Anterior distal femoral hemiepiphysiodesis in children with fixed knee flexion deformities: Where should the screws go?
Akshay Seth1, Patricia Miller2, Colyn Watkins2, Benjamin Shore2
1Children’s Hospital of Eastern Ontario (CHEO), Ottawa, Canada, 2Boston Children’s Hospital, Boston, USA
Introduction and Objective: Anterior distal femoral hemiepiphysiodesis (ADFH) using transphyseal screws is a guided growth technique used to correct fixed knee flexion deformities (FKFDs) in skeletally immature patients with neuromuscular conditions. There remains a lack of understanding of the technical elements of the procedure important for achieving success. The objective of this study was to determine whether the sagittal position of the screws used in ADFH affects the amount of physeal change over time.
Materials and Methods: This retrospective case series included pediatric patients with neuromuscular disorders treated for a FKFD using a transphyseal two-screw ADFH technique at a single centre from 2013 to 2020. Radiographs were reviewed to evaluate sagittal screw position and the change in the physeal angle over time. Relative to the sagittal physis, screw pairs were classified as being positioned anterior third-anterior third (AA), anterior and middle (AM) or middle-middle (MM).
Results: The study population included 68 knees in 36 patients. The mean physeal angle at the time of surgery was 93.5° (SD 3.5°), which increased to 102.5° (SD 5.7°) at 12 months, for a change of 9° (95% 7.5-10.5°, p < 0.001). At 24 months, the mean physeal angle was 105.6° (SD 6.2°) for a further change of 3.1° (95% 1.5-4.8°, p = 0.001). When stratified by screw position, in knees with AA and AM screws the physeal angle continued to increase through 24 months followup. However, for MM screws, there was a reversal of physeal angle change after 12 months.
Conclusions: A transphyseal two-screw ADFH procedure results in a change in the physeal angle of 9° in the first postoperative year. However, there is a slowing of physeal angle change after 12 months, with screws placed in the middle third of the physis reversing physeal change. This highlights the importance of proper surgical technique to achieve good outcomes.
Neuromuscular 1
OP-086
Early versus late scoliosis correction in Duchenne muscular dystrophy (DMD): Comparison of post-operative outcomes in the steroid era
Ali Asma1, Armagan Can ulusaloglu1, Michael W. Shrader1, William Mackenzie1, Robert Heinle1, Mena Scavina1, Jason Howard1
1Nemours Children’s Hospital, Delaware, Wilmington, USA
Introduction and Objective: Prior to the introduction of steroid management in DMD, early scoliosis correction (at 25-30°) was advocated, prior to substantial PF decline. With reduced rates of both PF decline and curve progression with steroid treatment, the role of early surgery has been questioned. The objective of this study was to compare the post-operative outcomes of early versus late scoliosis correction in DMD.
Materials and Methods: Retrospective cohort. Patients with DMD who underwent posterior scoliosis correction, had pre-operative PF testing, were included; divided into 2 Groups by pre-operative curve angle - 1: ≤ 45°, 2: > 45°. Primary outcome was post-operative complications by Clavien-Dindo (CD) grading. Secondary outcomes included: forced vital capacity (FVC), steroid utilization, fractional shortening (FS, echocardiogram), peri-operative outcomes, and curve correction. Statistical analysis by two-tailed t-test/chi-square testing.
Results: 31 patients met the inclusion criteria, with a mean follow-up of 8.3 ± 3.2 years. Steroid treatment (prednisone, deflazacort) was utilized for 21 (67.7%) patients, for 8.2 ± 4.0 years. Groups were comparable for steroid use, FVC, echo FS, and age at surgery. Primary curve angle was 31.7 ± 10.4° and 58.3 ± 11.1° for Groups 1 and 2, respectively (p < 0.001). Curve correction was not different between Groups [65% ± 27.3 vs 71.4% ± 11.7, respectively (p = 0.37)]. There were no significant differences in CD grades between Groups [1/2 (n): CDI, 1/0; CDII, 3/7; CDIII, 0/2; CDIV, 0/1; CDV, 0/0] (p > 0.05). For the entire cohort, however, the overall complication rate was higher for patients with steroid treatment [61.9% vs 10%, respectively (p = 0.008)], the majority being CDII. Neither FVC nor FS were different between Groups at final follow-up (p = 0.6; p = 0.4, respectively).
Conclusions: Due to similar complication rates between early and late surgery, delaying scoliosis correction in DMD while PF is favourable is reasonable, but patients with prior steroid treatment should be counseled regarding the higher risk of complications; particularly blood transfusion and deep infection.
TRAUMA 1
OP-088
Development of a core outcome set for childhood limb fractures
Ben Marson1, Joseph Manning2, Marilyn James3, Simon Craxford1, Sandeep Deshmukh1, Daniel Perry4, Benjamin Ollivere1
1Orthopaedics and Trauma, 2School of Health Sciences, University of Nottingham, Nottingham, United Kingdom, 3Clinical Trials Unit, Nottingham, United Kingdom, 4University of Liverpool, Liverpool, United Kingdom
Introduction and Objective: A lack of outcome consistency limits the meta-analysis of childhood fracture studies. A core outcome set is a group of critical outcome domains that should be measured in all research studies to ensure consistency between trials. This abstract presents the development of the Core-kids core outcome set using international standard methodology.
Materials and Methods: In line with COMET guidelines, the core outcome set was developed in three phases: 1) Identification of candidate outcome domains through systematic review and in-depth interviews with children and their families; 2) Prioritisation of outcome domains through an international, three-round Delphi study; 3) Agreement of a core set of domains through a Technology of Participation consensus meeting.
Results: The systematic review and interviews identified 85 outcome domains as potentially relevant. The Delphi survey prioritised 30 upper and 29 lower limb outcome domains at first round, an additional 17 upper and 18 lower limb outcomes at second round and four additional outcomes for upper and lower limb at the third round as important domains. At the consensus workshop, the core outcome domains were agreed as: 1) Pain & discomfort, 2) Return to physical & recreational activities, 3) Emotional & psychosocial well-being, 4) Complications from the injury and treatment, 5) Return to baseline activities of daily living, 6) Participation in learning, 7) Appearance & deformity, 8) Time to union, 9a) Recovery of mobility and 9b) Recovery of manual dexterity was recommended as additional limb specific outcomes.
Conclusions: This core outcome set presents eight minimum outcome domains to measure across all trials of childhood fractures. These outcomes should form the basis for the reporting of trials and can be expanded to add fracture-specific outcomes if required. Future work will focus on evaluating outcome tools to measure these domains, based on evaluation of tool validity and reliability.
Trauma 1
OP-089
Casting, elastic intramedullary nailing, or external fixation for pediatric tibia shaft fracture: Which is the most appropriate treatment? A multicenter study
Introduction and Objective: Displaced closed tibia shaft fracture in children and adolescent were traditionally treated by closed reduction and casting (CRC). However, during the last years, there was an increasing trend toward surgical management of these fractures. The main objective of this study was to retrospectively evaluate and compare outcomes and complications of displaced closed tibial fractures in children treated by CRC, elastic intramedullary nailing (EIN) or external fixation (EF).
Materials and Methods: 120 consecutive children were treated for displaced closed tibia shaft fracture from July 2014 and January 2020 at two different institution. 75 of them met the inclusion criteria and were included in the study: 30 (40%) patients were treated by CRC, 33 (44%) with EIN, and 12 with EF (16%). All clinical and radiographic outcomes and complications were registered and compared.
Results: The three groups did not differ with regard to gender, affected side, fracture site and associated fibula fracture. The age at the time of treatment in the CRC group was statistically lower than in EIN and EF group (8.43 ± 3.52 years vs 10.39 ± 2.56 years vs 11.08 ± 3.55 years, respectively). Immobilization time and time to partial and total weight bearing were significantly reduced in EIN and EF groups compared to CRC group (p < 0.05). Overall, No statistically significant differences were found between the three groups regarding complication rate and clinical and radiographic outcomes between the three groups. However, in CRC group, 3 patients (10%) had lost of reduction and underwent EIN.
Conclusions: Surgical treatment is not contraindicated in children with displaced tibia shaft fractures. EF and EIN provide a faster mobilization and weight bearing recovery than CRC. However, apart from that, nonoperative treatment was as efficacious as surgical treatment. Preliminary data suggest that fractures with comminuted pattern have a better outcome if treated surgically with EF.
Trauma 1
OP-090
Virtual fracture clinic pathway for paediatric fractures: A prospective evaluation of 10,000 patients
Flavia Alberghina1, Paula Kelly1, Jacques Noel1, Carol Blackburn1, Turlough Bolger2, Patrick Kiely1, Jim Kennedy1, David Moore1, Patrick O’Toole1
1Children’s Health Ireland (CHI) at Crumlin, Dublin, Ireland, 2Children’s Health Ireland (CHI) at Tallaght, Tallaght, Ireland
Introduction and Objective: Paediatric trauma care has traditionally utilized a Face-to-Face (F2F) model of outpatient care. The authors hypothesized that most paediatric minor trauma care could be managed definitively on initial contact within the Paediatric Emergency Department (PED), with subsequent confirmation of treatment at an orthopaedic Virtual Fracture Clinic (VFC). We describe our experience, of 10,000 children, managed via a VFC pathway in the setting of a paediatric trauma service.
Materials and Methods: Data was prospectively collected on all patients referred to the VFC from the PED. Outcome data included, referral for urgent operative treatment, referral back to PED for further evaluation, referral to F2F clinic, and discharge rate. Cost analysis was performed using established costing for a VFC within the local Healthcare System.
Results: A total of 10,000 consecutive patients were referred to the VFC from the PED over a 4-year period. There were 5,555 (55.5%) males and 4,445 (44.4%) females. The average age was 9.4 years (0.5 -17 years). 76.5% (n = 7,650) of children were discharged via the Virtual Fracture Clinic. 22.8% (n = 2,280) were referred to a F2F clinic. A total of 0.7% (n = 70) were referred from VFC for immediate operative treatment. 5% (n = 383), of the discharged patients, required an unplanned Face-to-Face evaluation.
Conclusions: This prospective evaluation, of our first 10,000 children, has demonstrated that a virtual fracture clinic pathway for minor paediatric trauma is safe, effective and brings significant cost savings.
Trauma 1
OP-091
Medial epicondyle fractures in children: Operative versus non-operative treatment
1Orthopaedics, Boston Children’s Hospital, Boston, USA, 2Harvard Medical School
Introduction and Objective: Medial epicondyle fractures (MEF) are a common pediatric injury, however there is little consensus as to ideal treatment. We aimed to evaluate trends in the management of MEF at our institution and compare outcomes of operative and non-operative groups.
Materials and Methods: A single-center tertiary care departmental database was queried to identify patients who underwent treatment for MEF between 2003 and 2019. Children who underwent conservative treatment were compared with those who underwent surgical intervention. Clinical, demographic, and radiologic data were analyzed.
Results: 891 fractures were identified (53% female, mean age 11.4 years), of which 565 (63%) were treated with surgical intervention and 321 (37%) were treated conservatively. Surgical patients were older, had a shorter time from injury, nerve changes, sports injuries, elbow dislocations, more entrapped fragments, and increased displacement on AP xray (8mm versus 3mm). 162 fractures (18%) had a complication, including 45/325 (13.8%) of conservative and 117/565 (21%) of surgically treated fractures (p = 0.01). On multivariable analysis, each mm of radiographic displacement increased the odds of complication by 7% (OR = 1.07; p = 0.02). Fractures during sports had nearly two times the odds of complication compared to falls (OR = 1.89; p = 0.008) and fractures with associated dislocation had nearly two times the odds of complication compared those without a dislocation (OR = 1.87; p = 0.02). There was no effect on multivariable modeling of complications when surgical intervention was or wasn’t included in any model.
Conclusions: These results suggest multiple demographic and treatment variables influence the decision for conservative versus surgical management of MEF. Further, the risk of complications appears related to characteristics of the injury (displacement amount, elbow dislocation, sports injury) but not to treatment type, further highlighting the need for future randomized studies to better determine whether surgery or conservative treatment givesben improved outcomes after MEF.
Trauma 1
OP-092
Operative treatment of supracondylar humerus fractures - do we practice what we preach?
Morten Jon Andersen1
1Department of Orthopedic Surgery, Copenhagen University Hospital - Herlev and Gentofte, Herlev, Denmark
Introduction and Objective: Faulty reduction or fixation of pediatric supracondylar humerus fractures (SCHF) can lead to loss of reduction (LOR) or malunion. Wire configuration has been extensively investigated and support two divergent lateral-entry K-wires for stable fractures and either three divergent lateral-entry or two crossed K-wires for unstable fractures. We aimed to investigate if adequate surgical reduction and fixation of SCHF according to international standards were obtained.
Materials and Methods: We reviewed all SCHF at Herlev and Gentofte Hospital from 2017-2020. Age, gender, Gartland classification, reduction, K-wire configuration, and LOR were recorded. Type 2A fractures were defined as minimally displaced and stable and other types as displaced and unstable. Satisfactory reduction was defined as the anterior humeral line passing through the capitellum, the absence of rotation, varus and valgus, and less than 5 mm of displacement.
Results: We reviewed 171 fractures. Mean age was 6 years. 53 (31%) fractures were stable/minimally displaced. 8/53 (15%) minimally displaced fractures and 39/118 (33%) displaced fractures were inadequately reduced. 23/118 (20%) unstable fractures were fixed with two lateral-entry wires, 13 (8%) with three lateral-entry wires and 56 (33%) with crossed wires. In 50/171 (29%) cases K-wire placement suffered from improper technic. We found 4 (2,3%) reoperations due to LOR.
Conclusions: Satisfactory reduction was not achieved in 27% of cases. 20% of unstable fractures were only treated with two lateral-entry K-wires. K-wire configuration was technically faulty in 29% of cases. Focus should be on satisfactory reduction and adequate configuration of wires but equally so on the technical aspect of placing the wires to avoid instability and LOR.
Trauma 1
OP-093
What percent of pediatric femur fractures result from non-accidental trauma?
Hanna Omar1, Natalya Sarkisova1, Christopher Lee1, Rachel Goldstein1
1Children’s Hospital Los Angeles, Los Angeles, USA
Introduction and Objective: Fractures are the second most common clinical manifestation of child abuse, with the femur being the most common location for non-accidental trauma (NAT) related fractures. The reported proportion of pediatric femur fractures that result from NAT varies drastically in the literature, ranging 21% to 60%. The purpose of this study is to further assess what ratio of pediatric femur fractures are the result of NAT, and to examine the effect of patient age range on NAT prevalence.
Materials and Methods: Retrospective review of patients 0-36 months old diagnosed with a femur fracture between 1/1/04 and 4/9/19 at our institution. Patients with incomplete medical records were excluded. Incomplete medical records were defined as an absence of all femur fracture related documentation. NAT was defined as a positive workup, meaning NAT was identified via social services, skeletal survey, or ophthalmological exam.
Results: 299 patients were identified. 22 patients were excluded due to incomplete medical records. 37 patients had no mention of an NAT workup entirely. 43 patients did not undergo NAT workup due to lack of suspicion. 197 patients underwent an NAT workup. 16.2% (32/197) of patient femur fractures were determined to be the result of NAT. Of the 32 patients with NAT, 12 were female and 20 were male. The average age at presentation was 0.7 years old. Additional injuries were present in 40.6% (13/32) patients. A significant difference in NAT rates was found between the 0 to 12-month age group and both older age groups, X2 (2, N = 277) = 35.1026, p <.00001.
Conclusions: Over one quarter (28.9%) of patients seen for femur fractures were not screened for NAT as is recommended by the American Academy of Orthopaedic Surgeons Guidelines and Evidence Report. Of the patients that were screened, 16.2% (32/197) of patient femur fractures were determined to be the result of NAT.
Trauma 2
OP-094
Pediatric phalanx fractures: A retrospective study and review of the literature
Stéphanie Schizas1, Nicolas Lutz2, Elif Vardar2, Sophie Mercakert2, Pierre-Yves Zambelli2, Eri Samara2
1UNIL, Switzerland, 2CHUV - Centre Hospitalier Universitaire, Switzerland
Introduction and Objective: Conventional radiography is frequently performed in pediatric patients in whom finger fractures are suspected. However, until now, the rate of positive findings of finger radiographic examinations in pediatric patients is unknown. This study aimed to evaluate the number of positive findings in the standard radiographic examinations of finger injuries in pediatric patients in a level 1 trauma center systematically.
Materials and Methods: We conducted a retrospective study on all children 0-16 years old admitted for acute finger injury in the Emergency Department of a University Hospital during the first semester of 2019 and received a radiographic examination. Their demographic characteristics, fracture pattern, and treatment were then analyzed and interpreted.
Results: Of 478 finger injuries reviewed in this cohort, 160 X-rays revealed positive for fractures giving a fracture rate of 33.5%. More than half of them (51.9%) occurred in the age group of adolescents (11-16 years). Among all finger fractures, only 3.8% of them treated surgically.
Conclusions: In our study, a relevant amount of standard finger radiographs revealed a low fracture rate and a rare operative indication of 3.8%. Therefore, indications for X-rays should be checked properly and alternative procedures should be discussed. Clinical decision rules should be developed and the necessary pathways must be implemented to minimize radiation exposure, waiting time, and costs.
Trauma 2
OP-095
Anesthesia and secondary interventions can be avoided by casting overriding distal metaphyseal radius fractures in children under 11 without reduction in emergency department
Topi Laaksonen1, Nicolas Nietosvaara1, Jani Puhakka2, Antti Stenroos1, Yrjänä Nietosvaara1, Jussi Kosola3
1Helsinki New Children’s Hospital, Department of Pediatric Orthopedics and Traumatology, Helsinki, Finland, 2Schulthess Clinic, Department of Neurosurgery, Spine Center, Zürich, Switzerland, 3Kanta-Häme Central Hospital. Finland
Introduction and Objective: We assessed outcome and satisfaction to treatment of distal metaphyseal radius fractures in children with different management strategies in order to improve the quality of care.
Materials and Methods: All completely displaced distal metaphyseal radius fractures in children up to 15 years old treated in our institution during 2014-19 were included. Chosen treatment, length of hospital stay and complications were evaluated. Telephone interview was carried out to 100 (89%) patient’s guardians at 1.5-7.2 years after the injury to register pain, cosmetic and functional outcome. Satisfaction to treatment was assessed by the 7-point Likert scale. Chi-square test and Mann-Whitney U-test were used to calculate variables with statistically significant level set as p < 0.05.
Results: We treated 112 children with overriding distal metaphyseal radius fractures (one bilateral). Less than 11-year-old children sustained 73% of these injuries. Reduction of the fracture in the emergency department failed in 33/72 (46%) cases. Sixty patients had their fractures reduced under general anesthesia. Internal fixation was performed in 51 cases. The median length of hospital stay was 0 days (0-1) in children treated by casting in overriding position, and 2 (0-4) days in patients that had their fractures reduced. Secondary interventions were not performed to children treated by casting without reduction, compared to 33/86 children that had their fractures reduced (odds ratio 5.8 [95% CI 1.2-27.7, p < 0.05]. All 26 children treated without reduction were satisfied with the cosmetic and functional outcome, whereas some children whose fractures were internally fixed were not satisfied with the cosmetic (n = 6) or the functional outcome (n = 3) (p = 0.03). There was no difference in pain or satisfaction to given treatment (p > 0.05).
Conclusions: Reduction of overriding distal metaphyseal radius fractures in children is difficult and does not seem to improve cosmetic or functional outcome in children less than 11 years.
Trauma 2
OP-096
Seymour fractures. Better do not underestimate it
Laura M. Perez-Lopez1, Isabel Parada-Avendaño2, Melisa Stitzman1, Maria Luisa Cabrera1, Cesar Galo Garcia Fontecha1
1Sant Joan de Deu Children’s Hospital, University of Barcelona, Paediatric Orthopaedic Surgery and Traumatology Department, Esplugues de Llobregat, Spain, 2Hospital Miguel Servet, Universidad de Zaragoza., Paediatric Orthopaedic Surgery and Traumatology Department, Spain
Introduction and Objective: Following our experience and what literature reports, failure to recognize Seymour fractures could lead to complications as osteomyelitis, physeal growth alterations and/or nail aesthetic sequelae/dystrophy. Authors aim to analyze the functional results, management and complications of acute Seymour fractures treatment, and generalize the understanding of Seymour fracture and the awareness about its controversial treatment and its critical sequelae.
Materials and Methods: A retrospective observational study was conducted from January 1994 to December 2019. The inclusion criteria were all patients younger than 18 years old diagnosed and treated in the emergency service of our hospital for an acute Seymour fracture, presenting within 24 hours of injury, with or without associated lesions.
Results: A total of 30 patients were included in the study with an average age of 7.9 years old ± 3.9 SD. The mean follow-up was 10.75 months ± 8.6 SD. Suffering from infectious osteomyelitis seems to be less probable when a K-wire is used as a synthesis method (4.8%), rather than when not (50%) (p = 0.013 at Fisher test, OR = 0.050).
We observed the fact that the use of antibiotics, in any of the three possible administrations (intravenous antibiotic regimen, intravenous and later oral antibiotic at home or oral antibiotics), in relation to the non-use of antibiotics, can be considered as a protective factor against infections (p = 0.001; OR 0.04; 95% CI 0.006-0.2).
Conclusions: According to our results, we can suggest that, in acute Seymour fractures, the use of an antibiotic regimen causes a lower risk of infections and the fixation with a K-wire could reduce the infection rates. Promptly identification of these fractures with a standardized protocol covering irrigation, debridement, reduction, fixation and prophylactic antibiotics is needed to avoid complications.
Trauma 2
OP-097
Epidemiology of pediatric pelvic fractures registered in the Swedish Fracture Register
Yasmin Hailer1, Lisa Larsson2, Olof Wolf2
1Section of Paediatric Orthopaedic Surgery, 2Section of Orthopaedic Surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Introduction and Objective: Pediatric pelvic fractures are uncommon. Nonetheless, pediatric pelvic fractures are indicators of severe injuries, often motor vehicle accidents. Management of these fractures differ due to different biomechanical properties of the immature pelvis in a younger population. Non-surgical treatment is most common, with surgical treatment reserved for complex fractures. Long-term quality of life follow-up for pediatric pelvic fractures has rarely been investigated. We therefore aimed to describe the epidemiology of pelvic and acetabular fractures in pediatric patients reported in the Swedish Fracture Register (SFR).
Materials and Methods: From the SFR we retrieved data on all patients aged 6-17 at injury between January 2015 and February 2021. Descriptive analysis was performed for epidemiological variables such as age, sex, injury mechanism and energy-level, fracture classification, concomitant injuries and performed treatment.
Results: 223 patients had a registered pelvic fracture in the SFR; 201 pelvic fractures and 22 acetabular fractures. Mean age was 14.4 years and 61% of the patients were boys. The leading cause of injury was a fall, followed by a transportation accident. Girls suffered more often fractures from falls than boys, and boys suffered more often from vehicle accidents. The most common reported fracture was type A pelvic fractures (74% of all). 85% of fractures were treated non-surgically. Type C fractures (10) were all treated surgically. All type C fractures of the pelvis were in patients in the oldest age group.
Conclusions: In this nationwide observational cohort study of 223 pediatric pelvic fractures, we found a higher mean age than in previous studies. A fall was the most common mechanism of injury. More severe fractures were mainly seen with increasing age. The most common fractures were Pelvic type A, which were non-surgically treated. Surgical treatment was more common with increasing severity of the fracture-type.
Trauma 2
OP-098
Predictors of healing in paediatric tibial fractures using the RUST score: A 12 year retrospective review
Antony Roy1, Pranai Buddhdev1
1Trauma and Orthopaedics, Broomfield Hospital, Mid and South Essex NHS Trust, Broomfield Essex, United Kingdom
Introduction and Objective: There is a lack of consensus on the surgical management of pediatric tibial fractures. This study was carried out to identify various factors that affect healing in paediatric tibial fractures.
Materials and Methods: This was a single centre, retrospective analysis of a prospectively maintained database of paediatric tibial fractures treated operatively between 2008-2020. Patient demographics, injury characteristics (mechanism of injury, open/closed wound and presence of additional injuries), fracture characteristics (fracture configuration, level and presence of fibular fracture), method of management and post-operative complications were noted. The Radiographic Union Scale in Tibial fractures (RUST) scores were evaluated on radiographs at weeks 4, 8 and 12. The effect of the various parameters on healing was analysed by comparing the RUST scores.
Results: 83 patients (mean age:10.7 ± 4.11 years, M:F = 46:21) were included in the study. 67 (80%) and 16 (20%) patients underwent closed reduction (CR) ± fixation and open reduction-internal fixation (ORIF) respectively, with similar distribution of patient demographic, injury and fracture characteristics. The majority of the cases were closed injuries (88%), diaphyseal (72%), transverse in nature (41%), and caused by high energy trauma (56%). A negative correlation between increasing patient age and RUST scores was noted at weeks 8 (r: -0.3552, p = 0.001) and 12 (r: -0.3626 p = 0.0008). RUST union scores were not affected by gender, fracture configuration and presence of fibular fracture, however were significantly higher in lower energy traumas (p < 0.05) and metaphyseal fractures (mean difference:1.82 ± 0.38, p = 0.0003). RUST scores were higher in those who underwent ORIF (mean difference:1.4 ± 0.5; p = 0.012) when compared to the CR group. Mal/Non-union was noted in 3 patients in the CR group only.
Conclusions: The key parameters that can affect radiographic union of paediatric tibial fractures are older age, high-energy trauma mechanisms, diaphyseal and open injuries. Specific attention needs to be paid in these cases to ensure adequate union and return to function.
Trauma 2
OP-099
Comparison between two protocols of procedural sedation and analgesia in the treatment of pediatric both-bone forearm fractures
Joaquín Núñez De Armas1, Luis Moraleda Novo1, Gaspar González Morán1, Enrique Gil Garay2
1Unidad de Ortopedia Infantil, 2Servicio de Traumatología y Cirugía Ortopédica, Hospital Universitario La Paz, Madrid, Spain
Introduction and Objective: Manipulation of the fracture and immobilization with in a cast is the most common procedure for the treatment of both-bone forearm fractures (BBFF). Several methods have been employed by orthopaedic surgeons to perform this procedure adequately without risk for the patients. We aimed to study the effectiveness of nitrous oxide vs ketamine in closed reduction and long-arm cast immobilization for BBFF.
Materials and Methods: The study includes 66 children that sustained a BBFF treated in the ER with closed reduction under procedural sedation and analgesia. We compared the results when reduction was done using nitrous oxide (38 patients) or ketamine (28 patients). Both groups were compared regarding quality of reduction, quality of the cast, side effects and time in the ER.
Results: Both group were comparable regarding weight (p = 0.1), mechanism of injury (p = 0.3), location of radius fracture (p = 0,2), fracture pattern (p = 0.4), direction of deviation (p = 0.1), and radius angulation in the AP (p = 0.8) and lateral x-ray (p = 0.7). Quality of reduction, measured as radius angulation in the AP (p = 0.2) and lateral views (p = 0.9) or percentage of displacement of the radius in the AP (p = 0.9) and lateral views (p = 0.8), were similar between both groups. However, Padding index (0.37 vs 0.46) and Canterbury index (1.19 vs 1.28) were better in the ketamine group: (p = 0.01 and p = 0.05, respectively). Ketamine group showed also side effects more frequently (27% vs 8%; p = 0.03). Time expended in the ER was higher in the ketamine group: 249 vs 175 minutes (p = 0.02).
Conclusions: Ketamine allows a better molding of a long-arm cast after closed reduction of BBFF. However, it increases the time expended in the ER and causes more minor side effects compared to nitrous oxide. The type of drug used for procedural sedation and analgesia in the ER did not affect quality of reduction.
Trauma 2
OP-100
Displaced tibial shaft fractures in children: Method of treatment in children weighing 50 kg or more
1Institute of Medicine, College for Medical Sciences of University of Rzeszow, Rzeszów, Poland, 2Department of Pediatric Orthopedic, Clinical Regional Hospital No. 2, Rzeszów, Poland
Introduction and Objective: Currently considered the gold standard in surgical treatment of displaced tibial shaft fractures in children with open growth cartilage is Elastic Stable Intramedullary Nailing (ESIN). Purpose of this study is analysis of indications, complications and duration of treatment using intramedullary flexible nails in children who are still growing but especially weighing 50 kg or more.
Materials and Methods: Hospital records from May 2017 to June 2020 were retrospectively reviewed to identify all the children with tibial shaft fracture admitted to the Pediatric Orthopedic Department. Standard demographic data were collected. Only children with open growth cartilage, a minimum of six months follow-up and complete clinical data were considered for the study.
Results: Studies of 102 children between the age of 2 to 17 years were analyzed. The average patient age at the time of the injury was 11 ± 3.26 years old. There were identified 72 (70.6%) males and 30 (29.4%) females in this group. 92 (90.2%) children were treated using ESIN, 8 (7.8%) using intramedullary nail and 2 (2%) patients underwent closed reduction with applying above-knee cast. In ESIN group 35 (38%) children weighed minimum 50 kg (range 50-105 kg). The mean time to nails removal was 8.4 ± 3.2 months in the whole group of children stabilized with ESIN, while in the subgroup of children weighing minimum 50 kg this time was only slightly extended, statistically insignificant (p > 0.05).
Conclusions: This study demonstrates that the use of ESIN in displaced tibial shaft fractures in growing children and adolescents weighing 50 kg or more is acceptable and relatively safe. The expected healing time, which affects the total treatment time, is only slightly extended.
Best of Trauma
OP-101
The use of clinical photographs and patient reported outcome questionnaire as a tool to predict functional outcome in supracondylar humeral fractures treated operatively
Marie-Caroline Nogaro1, Senol Bekmez1, Mark Camp1, Unni Narayanan1
1The Hospital for Sick Children, Toronto, Canada
Introduction and Objective: 500+ supracondylar humeral fractures (SCHF) are treated at Sickkids each year, who are seen in clinic at 3 weeks for pin removal, and 3 months post-op, when most patients are reportedly normal. We investigated whether photographs and/or patient-reported outcome measure (PROM) scores could identify patients who do not need 3-month in-person follow-up.
Materials and Methods: At the 3-month visit, 248 SCHF patients (mean 6.2 yrs; 0.75-11yrs) had bilateral elbow motion (ROM) and carrying angles measured; and photographs of full length frontal and sagittal alignment, and maximum elbow flexion/extension. Two independent assessors made the same measurements off the clinical photographs to compare these with the clinic measurements. Two PROMs: Self-Assessment Questionnaire (SAQ: 0 best to 14 worst) and QuickDASH (0 best to 100 worst) were completed at the 3-month visit.
Results: Inter-rater reliability of the photograph measurements was excellent (Kappa: 0.88-0.93), but weakly concordant with clinical measurements (carrying angle Kappa = 0.51; max flexion Kappa = 0.68; max extension Kappa = 0.64). SAQ moderately correlated with QuickDASH (Kappa = 0.59) and performed better at identifying patients with abnormalities. SAQ score ≥ 4 identified patients meeting 3-month follow-up criteria, with sensitivity: 36.1%; specificity: 96.8% and negative-predictive-value (NPV): 87%.
Conclusions: Photographs are not reliable. Although SAQ-score has high NPV, a more sensitive fracture-specific PROM is needed to identify patients who do not need a 3-month follow-up visit.
Best of Trauma
OP-102
Intramedullary fixation for pediatric femoral nonunion in low- and middle-income countries
Ryan Furdock1, Lauren Huang1, George Ochenjele2, Lewis Zirkle3, Raymond Liu1
1Rainbow Babies & Children’s Hospital at Case Western Reserve University, Cleveland, USA, 2UH Cleveland Medical Center, Cleveland, USA 3Sign Fracture Care International, Richland, USA
Introduction and Objective: Pediatric femoral shaft non-unions are uncommon in the USA after plating or intramedullary nailing (IMN) but are more frequent in low and middle-income countries. SIGN Fracture Care International (SIGN) offers education, instruments, and implants free-of-charge if adequate surgical data is registered for quality control. We studied the efficacy of SIGN IMN for pediatric femoral shaft non-union in lower resource settings.
Materials and Methods: The SIGN database was queried to identify all 85 cases (84 patients) of pediatric femoral shaft nonunion since 2003 with a follow-up visit available. Nonunion was defined as failure of initial plate or IMN instrumentation > 90 days following its placement. Patients were excluded for lack of 3-month follow-up (n = 12), inadequate record (n = 8), missing lateral view on radiographs (n = 5), additional revision implants other than SIGN nail (n = 2), or non-union following osteotomies (n = 1). An orthopaedic traumatologist, pediatric orthopaedic surgeon, and an orthopaedic surgery resident evaluated each patient’s final follow-up radiograph as a committee to determine a radiographic union scale in tibial fractures (RUST) score. RUST scores of ≥ 9 were considered treatment successes. Demographics and rates of painless full weightbearing were recorded.
Results: Fifty-seven pediatric femoral shaft nonunion cases (42 males, 15 females; 18 countries) were eligible for inclusion. Average age at revision surgery was 13.8 ± 3.0 years (range 6-17). Median follow-up was 63 weeks (range 13 weeks - 7.7 years). Initial failed instrumentation included plate constructs (77.5%), non-SIGN IMNs (17.5%), and SIGN IMNs (5%). The average RUST score at final follow-up was 11.3 ± 1.2 (range 8-12). At final follow-up, 95% (54/57) of cases achieved RUST scores of ≥ 9 and 90% (51/57) of patients had painless full weightbearing.
Conclusions: Pediatric femoral shaft nonunion can occur after both plate fixation and intramedullary nailing in low- and middle-income countries. SIGN intramedullary nailing is an effective treatment for these patients.
Best of Trauma
OP-103
Outcomes of suture-button versus screw fixation for pediatric and adolescent syndesmosis injuries
Emily Chang1, Blair Stewig1, Amy Steele1, Patricia Miller1, Dennis Kramer1, Yi-Meng Yen1, Benjamin Shore1, Collin May1
1Orthopaedics, Boston Children’s Hospital, Boston, USA
Introduction and Objective: Multiple high-level studies in the adult literature suggest that suture-button implants may be superior to screw fixation for syndesmosis injuries, however, no such data exists in the pediatric population to guide treatment. The aim of this study was to review our institutional experience in the operative treatment of syndesmotic ankle injuries in children and adolescents, and to compare outcomes between patients treated with suture-button versus screw fixation
Materials and Methods: A single center tertiary care departmental database was queried for patients aged 2-18 treated surgically for syndesmotic ankle injury between 2003 and 2019. Demographic information, injury characteristics, radiographic data, and clinical and functional outcomes were collected and compared between groups.
Results: One hundred seventy-four patients were analyzed (64% male, mean age 16.2 years), of which 129 (74%) were treated with screw fixation and 45 (26%) were treated with suture-button. There were no differences detected in demographic, injury, or treatment characteristics between groups. Radiographic outcomes showed significant improvement in ankle alignment across all patients from pre- to post-operative films, however there was no difference between fixation types. Other outcomes, including return to weight bearing, return to sport/activity, and pain level, were comparable between groups. Complication rates (excluding hardware removal) were similar between groups (18% with screw and 20% with suture-button, p = 0.92). Rates of hardware removal were significantly different, however, with 108/129 (84%) of screws and 18/45 (40%) of suture-button implants undergoing removal (p < 0.001).
Conclusions: Suture-button and screw fixation of syndesmosis injuries leads to similar clinical outcomes, however the decreased rate of secondary surgery may be a factor explaining the trend toward increased suture-button use. Future study is needed to better understand the role of surgeon preference in choice of treatment and to further elucidate whether suture-button or screw fixation is indeed superior.
Best of Trauma
OP-104
Diaphyseal forearm fractures treated by bioabsorbable intramedullary nailing - Challenges to use the nailing technique
Gergő Józsa1, Annelie Martina Weinberg2, Nicolas Lutz3, Morten Jon Andersen4, Erich Rutz5, Marcell Varga6
1Department of Paediatrics, Division of Paediatric Surgery, Traumatology, Urology and Paediatric Otolaryngolgy,József Attila Street, Medical Centre, Pécs, Hungary, 2Department of Orthopedic and Orthopedic Surgery, Graz, Medical University Graz, Graz, Austria, 3Department of Pediatric Surgery and Orthopedics, Lausanne University Medical Center, Switzerland, Lausanne, Switzerland, 4Department of Orthopedic Surgery, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark, 5Pediatric Orthopedic Department Parkville, The Royal Children’s Hospital, RCH, Melbourne, Australia, 6Paediatric Trauma Department, Peterfy Hospital and Manninger Jenő National Trauma Center, Budapest, Hungary
Introduction and Objective: Forearm fractures are common injuries in childhood. Completely displaced and unstable fractures require surgical intervention. Elastic Stable Intramedullary Nailing (ESIN) is widely used in treating these fractures. Although stainless steel and titanium implants are the most widely used, resorbable nails are becoming an option. We aim to present the intraoperative difficulties and complications related our initial experience in treating forearm fractures in children with Resorbable Stable Intramedullary Nailing (ReSIN).
Materials and Methods: A prospective multicenter study started in 9/2020, including 8 centers from 7 countries. Inclusion criteria are children aged 3-12 years with a closed diaphyseal forearm fracture needing reduction and osteosynthesis. Exclusion criteria are comminuted or wedge fractures and associated bone diseases. Analysis of intraoperative difficulties and complications during the operative procedure are identified and discussed during regular study meetings. The data was retrieved from the patient charts and critical descriptive analysis was performed.
Results: Fifty-four patients were included. 33 boys, 21 girls, mean age 8,9 years (±2.9) Complications included 1 nerve lesion (superficial branch of Radial neve), 1 migration of an implant fragment, 2 secondary malalignment < 15 degrees (with 2 mm diameter nails), 2 superficial wound infections. Technical difficulties included intraoperative corticalis penetration with the dilatator in two patients, requiring change of strategy, in two patients transient difficulty in advancing the nail.
Conclusions: ReSIN complications were not different from those encountered with ESIN. Technical difficulties can be avoided by meticulous preoperative planning, analysis of the fracture type, shape of the medullary canal, and choice of nail diameter. A learning curve phenomenon was noticeable in all participating centers.
Best of Trauma
OP-105
Is the X-ray control 4 weeks after ESIN osteosynthesis of forearm fractures an indispensable standard or can it be spared?
Sven-Oliver Dietz1, Nora Laubach1, Martin Schwind2, Pol Rommens1
1Department of Orthopaedics and Traumatology, 2Department of Paediatric Surgery, University Medical Center, Mainz, Germany
Introduction and Objective: Fractures of the forearm diaphysis are among the most common fractures in children. Closed reduction and internal fixation with ESIN is the surgical standard care. According to guidelines, X-ray controls should be performed on the first day postoperative, after 4 weeks and before implant removal. If callus formation is visible after 4 weeks, the children are allowed to return to sports 2-4 weeks later. We performed a single-centre, retrospective evaluation if the X-ray control after 4 weeks has any impact on standard operating procedures in otherwise healthy children.
Materials and Methods: N = 200 patients (median age 7.5 ± 3.1 years; n = 88 female, n = 112 male) who were treated by means of closed reduction and ESIN osteosynthesis for diaphyseal forearm fractures between 01/2014 and 07/2018 were included in our study. In n = 163 radiological and clinical data were complete.
Results: Of the163 patients only n = 14 patients were not allowed to return to sports 6-8 weeks post-operative. Of these n = 7 suffered a re-fracture after adequate de-novo trauma. The further n = 7 patients had irritating ESIN prominence, persistent limited range of motion, deterioration of general health status, suspected child abuse, tender fracture site, an initially missed additional olecranon fracture or delayed callus formation respectively.
Conclusions: Merely 14 of 163 children were not treated according to standard operating procedures. Of these n = 7 had a re-fracture. In further n = 6 children the pathologies were either detected clinically or after revision of the initial X-rays. Thus the X-ray after 4 weeks led only in n = 1/163 children (0.6%) to therapeutically consequences. These results justify a prospective multi-centric investigation whether X-rays 4 weeks after ESIN osteosynthesis in diaphyseal forearm fractures are indicated.
Best of Trauma
OP-106
Complications in elective removal of bone lengthening nails: A report of 225 patients
Markus Winther Frost1, Ole Rahbek1, Søren Kold1, Anirejuoritse Bafor2, Molly Duncan2, Christopher Iobst2
1Department of Orthopaedics, Aalborg University Hospital South, Aalborg, Denmark, 2Department of Orthopaedics, Nationwide Children’s Hospital, Center for Limb Lengthening and Reconstruction, Columbus, USA
Introduction and Objective: Due to high complication rates with external fixators, externally controlled motorized intramedullary lengthening nails have been introduced. These lengthening nails have shown excellent short-term results. For the most frequently used intramedullary lengthening nails (FITBONE, PRECICE, STRYDE), the producers acclaim removal of the implants after accomplished treatment. Despite the requirement for nail removal, there is a lack of reports of complications on intramedullary lengthening nail removal. The aim was to examine the intraoperative and postoperative complications of elective intramedullary lengthening nail removals.
Materials and Methods: A retrospective chart review of patients operated with intramedullary lengthening nails at Nationwide Children’s Hospital, USA and Aalborg University Hospital, Denmark were performed. Patient demographics, nail-information, and any complications occurring at or after nail removal were recorded. Only elective nail removal of FITBONE and PRECICE or STRYDE nails in lower limb were included. Bone transport, stump lengthening and humeral lengthening were excluded.
Results: A total of 225 patients with 271 elective nail removals were included. The mean (min-max range) follow-up time after nail removal was 282 days (0 - 2882 days). In 3 % complications occurred during nail removal and in 13% after nail removal. Postoperative knee pain was reported in 18 cases, who all had nail removal through the knee joint, representing 8% of the retrograde femur nail removals and 7% of the tibia nail removals. 2 of the 4 postoperative fractures that occurred needed surgery. For femur and tibial nail, complications were 11% and 26% respectively.
Conclusions: This is the first study examining complications in removal of bone lengthening nails. In 16 % of 271 nail removals a complication occurred at or after nail removal. This emphasizes that studies reporting on the overall risks of complications of bone lengthening nails must include nail removal and an adequate follow-up after this.
Best of Hip and Neuromuscular
OP-107
How much remodelling can we expect after fixation in situ of SCFE? A multicentric study of the German Speaking Paediatric Orthopaedic Society
Fritz Hefti1, Danimir Cerkez2, Katharina Burger3, Bjoern Vogt4, Bernd Bittersohl5, Kiril Mladenov6, Kerstin Dr. Remmel7
Introduction and Objective: Open questions: Is cam-impingement an inevitable consequence of SCFE? In which cases is fixation in situ sufficient?
Materials and Methods: Data were prospectively collected in 9 pediatric orthopaedic units in German speaking countries. 220 hips had fixation in situ (FIS) (94x pins, 126x screws). Ap and axial x-rays were evaluated at diagnosis, postoperatively and at end of growth, MRIs were available in 175 patients. Average FU-time was 3.6 years (2-8.6y.). Acute and chronic were classified according to whether or not adaptive bone changes were visible on initial x-rays. Besides head-neck-angle, the α-angle, offset and translation of the head-centre, neck-shaft-angle and the relation between neck-length and -thickness were measured in a standardized way. Classification at end of growth: «Abnormal hip» (cam deformity) = α-angle > 55° or head offset < 8 mm or head-neck-angle > 30° or internal rotation ≤ 15°. The others were either normal or nearly normal. A 4th group was «disaster» (AVN or implant perforation).
Results: Of 99 «acute» cases only 23% were abnormal (cam-deformity) at the end of growth, 1% had AVN. Of 121 «chronic» cases 47% were abnormal and 4% were classified as a disaster. The neck-shaft angle and the relation between neck-length and -width were significantly smaller on the affected than on the contralateral side (with prophylactic fixation).
Conclusions: If no adaptive bone changes are present, fixation in situ is always indicated. If, however, there are bone changes, dislocation of the posterior margin of the femoral head of more than 4 cm from its original site is an indication for an open reduction. All others have a good chance to remodel. Residual cam impingement can be corrected in a secondary procedure if necessary. Increased varus and shortening of the femoral neck is an inevitable consequence of SCFE and is not dependent on the method of fixation.
Best of Hip and Neuromuscular
OP-108
Prospective evaluation of in situ screw fixation for slipped capital femoral epiphysis
Clarabelle DeVries1, Raghav Badrinath1, Samuel Baird1, James Bomar1, Vidyadhar Upasani1
1Orthopedics, Rady Children’s Hospital - San Diego, San Diego, USA
Introduction and Objective: In situ screw fixation is the standard of care for the treatment of stable slipped capital femoral epiphysis (SCFE). The purpose of this study was to prospectively evaluate radiographic and patient reported outcomes (PROs) after in situ screw fixation for stable SCFE with minimum 2-year follow-up to determine which patients develop FAI and require secondary surgical procedures.
Materials and Methods: We prospectively collected data on consecutive SCFE patients who underwent in situ screw fixation at a single institution. Demographic and radiographic information, as well as PROs were collected. Basic descriptive statistics, the Mann-Whitney test, and correlation analyses were performed.
Results: Fifty-four hips in 46 patients with an average pre-op Southwick slip angle (SSA) of 40.5° ± 19.4° were studied. We observed one complication following the index procedure (2%). Twelve hips (22%) went on to have a secondary procedure on average 2.7 ± 2.2 years after the index surgery. Our mean post-op Hip disability and Osteoarthritis Outcome Score (HOOS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores were 84.6 ± 16.7 and 87.9 ± 14.8, respectively. Severe slips were 14.8 times more likely to undergo a secondary procedure than mild and moderate slips (p < 0.001), however we found no correlation between slip severity and PROs (p > 0.6). Hips that required a secondary procedure were found to have significantly lower HOOS scores (76.8 ± 18.4) at final follow up compared to hips that did not require additional surgery (86.8 ± 15.7) (p = 0.042).
Conclusions: With minimum 2-year follow-up, 22% of patients went on to require a secondary surgery. PROs did not correlate with slip severity (p > 0.6) and were found to be significantly higher in SCFE patients that did not require a secondary procedure (p = 0.042). Prophylactic treatment of all slip-related cam deformity was not found to be necessary in this prospective cohort. Patients with moderate to severe slips may require secondary surgery.
Best of Hip and Neuromuscular
OP-109
Comparison of acetabular morphology changes after pediatric pelvic osteotomies using patient-specific 3-D models
Samuel Baird1, Jason Caffrey1, James Bomar1, Christine Farnsworth1, Vidyadhar Upasani1
1Rady Children’s Hospital - San Diego, San Diego, USA
Introduction and Objective: A variety of surgical management options exist to improve hip joint morphology in patients with acetabular dysplasia. The purpose of this study is to evaluate the differences in acetabular morphology between four osteotomies using patient-specific 3-D printing technology.
Materials and Methods: Quadruplicate pelvis models were created from preoperative computed tomography (CT) scans from patients with acetabular dysplasia. Pemberton, Dega, San Diego, and Salter osteotomies were performed on the quadruplicate sets. CT scans were obtained of the 3-D printed pelvises before and after mock surgeries. Acetabular volume and regional coverage angles were computed and compared before and after each acetabuloplasty.
Results: Fourteen hips (14 patients) were included; 1 male, 13 female; age 5.4 ± 1.3 years (range: 3 to 7 years). Acetabular volume decreased by 14% for the Pemberton, 19% for the Dega, 19% for the San Diego, and 6% for the Salter, with a smaller volume reduction for the Salter than the other three procedures (p < 0.05). Change in volume was similar between the Pemberton, Dega, and San Diego osteotomies (p = 0.32). The San Diego increased coverage in the Posterior, Superior-Posterior, and Superior regions (p < 0.05). The Salter increased coverage in the Superior region alone (p < 0.05). The Pemberton increased coverage in the Superior and Anterior regions, and the Dega increased coverage in Superior, Superior-Anterior, and Anterior regions (p < 0.05).
Conclusions: Acetabular volume changes found in this study support the conventional belief that redirectional osteotomies such as the Salter are more volume neutral than incomplete osteotomies such as the Pemberton, Dega, and San Diego. However, even the Salter decreased acetabular volume. Additionally, this study re-demonstrated that each osteotomy used for correction of acetabular dysplasia uniquely changes acetabular coverage in different regions. Based on these findings, the decision between which pediatric pelvic osteotomy should be based on the morphology of the dysplastic acetabulum.
Best of Hip and Neuromuscular
OP-110
Clinical and kinematic outcomes after femoral rotational osteotomy
Jeremy Bauer1, Patrick Do1, Jehan Hamid2
1Shriners Hospitals for Children, Portland, USA, 2Concord Repatriation General Hospital, Concord, NSW, Australia
Introduction and Objective: Idiopathic torsional deformities (ITD) cause adolescent knee pain, patellofemoral instability, femoroacetabular impingement and running difficulty. Our aim was to compare the range of motion, kinematics and patient reported outcomes of patients with ITD following femoral derotational osteotomy (FDRO).
Materials and Methods: We conducted a retrospective review of all children from our database who underwent an FDRO to compare internal femoral torsion (IFT) and external femoral torsion (EFT). We analyzed pre- and post-operative standardized physical examination, three-dimensional gait analysis (3DGA) and Pediatric Outcomes Data Collection Instrument (PODCI) questionnaires. Comprehensive gait analysis was also done on 20 typically developing children (TD) as a control group. Statistical analysis was completed using two sample t-tests and Pearson’s correlation.
Results: There were 54 children in total, 37 children with IFT and 17 children with EFT. The FDRO corrected passive hip rotation for both groups to match the control group. 3DGA kinematics found hip rotation in stance changed 12.2° ± 9.6° for IFT and 12.8° ± 9.7° for EFT. The resulting mean hip rotation in stance was -1.4° ± 8.3° for IFT and -5.7° ± 8.8° for EFT. The PODCI significantly improved for the IFT group for transfer/basic mobility, sports/physical function, global functioning and satisfaction with symptoms.
Conclusions: For adolescents with symptomatic ITD, we found surgical correction, successfully improved passive range of motion (ROM) to within the normative values. This is the first study to report on outcomes of adolescents with EFT. We subsequently found on 1-year follow up that while the IFT group maintained hip rotation during gait the EFT group continued walking in external hip rotation. Adolescents with IFT undergoing an EFDRO reported more consistent improvements in patient reported outcomes in comparison to those with EFT undergoing an IFDRO.
Best of Hip and Neuromuscular
OP-111
Proximal femoral screw hemiepiphysiodesis can alter the growth of the proximal femur in children with cerebral palsy
James McCarthy1, Allyson Zakrzewski1, Jacob Carl2
1Division of Orthopaedics, Cincinnati Children’s Hospital, Cincinnati, USA, 2Division of Orthopaedics, Shriner’s Hospital for Children-Spokane, Spokane, USA
Introduction and Objective: Proximal Femoral Screw Hemiepiphysiodesis (PFSH) is a promising technique to treat hip dysplasia in children with CP. Early animal and clinical cohort studies have shown improvements in radiographic measures. The aim of this study is to evaluate the radiographic parameters after PFSH, as compared this to changes that occurred in the two years prior to surgery.
Materials and Methods: A single center retrospective chart review of children with CP who underwent PFSH with a minimum of 2 years of radiographic follow-up was performed. Demographic and clinical/surgical complications, need for screw exchange, and additional procedures were recorded. Migration Percentage (MP), Neck Shaft Angle (NSA), Head Shaft Angle (HSA) were assessed on AP Pelvis radiographs: 2 years prior to surgery, pre-operatively, post-operatively and at follow-up. Patients were divided into two groups: Group I had no previous hip surgery and Group II had PFSH performed at the time of hardware removal after hip reconstruction.
Results: There were 23 patients (44 hips), mean age 7.3 years, follow-up of 33 months. Group I had 32 hips and Group II had 12. Group I had improvements between pre-operative and follow-up (p < 0.05) in all measurements: MP 5%, NSA 13°, HSA 15°. In Group 2 significant improvements were only seen in HSA 8°. In both groups the 2 year pre op (natural history group N = 25) measurements all worsened. Twelve hips underwent screw exchange at an average of 34 months (range 27 - 42) with 2 hips undergoing pelvic osteotomy. Three hips had migration percentage > 50% at follow- up, 2 underwent hip reconstruction. There were no intraoperative complications or fractures associated with this procedure.
Conclusions: PFSH is a minimally invasive procedure that can alter the growth of the proximal femur. Screws may need to be exchanged and hips need to be carefully monitored.
Best of Hip and Neuromuscular
OP-112
Morbidity of the Dega pelvic osteotomy after triradiate closure in patients with cerebral palsy. A comparative study
Thomas Krausse1, Brice Ilharreborde1, Cindy Mallet1, Jason Chinnappa1, Florence Julien-Marsollier1, Ana Presedo1, Anne-Laure Simon1
1Hôpital Robert Debré, Paris, France
Introduction and Objective: Non ambulant children with cerebral palsy (CP) are likely to develop a neurological hip dislocation. Despite early management, some children develop dislocation after closure of the triradiate cartilage, which is the usual hinge point for the Dega osteotomy. The feasibility of this procedure despite a closed tri-radiate cartilage has already been proven. The aim of this study was to investigate the morbidity of the Dega pelvic osteotomy in patients with CP at skeletal maturity.
Materials and Methods: A retrospective analysis of all consecutive hip reconstructions with a Dega pelvic osteotomy in non-ambulant CP children between 2011 and 2019 was performed. 2 groups were compared according to preoperative pelvic radiographs findings: Group 1, before triradiate cartilage closure (TCC) and Group 2, after TCC. Intra- and perioperative data regarding bleeding were reported, as well as postoperative complications and radiological follow-up at a minimum of 2-years
Results: 63 patients were operated on between 2011 and 2019: 34 in the Group1 (mean age 10.4 ± 2.1 years) and 29 in the Group2 (mean age 14.6y ± 2.7 years). Rate of transfusion was similar between groups (23.5% vs 31%, p = 0.6) as well as mean blood loss (295 ± 190 mL vs 380 ± 220 mL, p = 0.2). Rate of complications was 9% in Group 1 (hematoma, femur fracture, mechanical failure) and 17% in Group 2 (early dislocation, femoral head avascular osteonecrosis, mechanical failure and surgical site infection), without significant differences between the groups (p = 0.5). 2-year pelvic radiographs showed no significant differences according to the Reimer’s migration index and the acetabular inclination.
Conclusions: The Dega pelvic osteotomy in hip reconstruction for non-ambulant children at skeletal maturity has similar short-term results to the same reconstruction in skeletally immature children, with no difference in peri-operative morbidity.
Lower Limb Deformity
OP-113
Radiographs of 366 removed internal lengthening nails reveal differences in bone abnormalities between different nail types: Fitbone, Precice and Stryde
Christopher Iobst1, Markus Winther Frost2, Søren Kold2, Ole Rahbek2, Anirejuoritse Bafor1, Molly Duncan1, Jan Duedal Rölfing3
1Orthopedic Surgery, Nationwide Children’s Hospital, Columbus, USA, 2Department of Orthopaedics, Aalborg University Hospital, Aalborg, Denmark, 3Department of Orthopaedics, Aarhus University Hospital, Aarhus, Denmark
Introduction and Objective: The recent adverse events and high frequencies of radiographic changes noted with the Stryde lengthening nail have raised concerns about the use of internal lengthening nails. The aim was to compare the prevalence of radiographic bone abnormalities between Stryde, Precice and Fitbone nails prior to nail removal.
Materials and Methods: After obtaining Institutional Review Board approval, a retrospective case series from three centers was performed. Patients were included if they had one of the three internal lengthening nails (Fitbone, Precice, or Stryde) removed. Standard orthogonal radiographs immediately prior to nail removal were examined for bone abnormalities at the junction of the telescoping nail ends, at the interlocking screw/peg sites and at the blocking screw sites.
Results: 306 patients had 366 internal lengthening nails removed. The mean from nail insertion to radiographic evaluation was 434 days. 77% (20/26) Stryde nails had bone abnormalities at the interface compared with only 2% (4/242) of Fitbone and 1% (1/98) of Precice nails (p < 0.0001). In addition, the extent of bone abnormalities were more pronounced in the Stryde nails compared with the other nails. Bone reaction around the interlocking screws/pegs occurred in the thin part of the nail. The reaction was mainly cortical hypertrophy. The frequency of bone reaction at the interlocking screw/peg was significantly higher for the Fitbone nail (p < 0.05). In multiple cases bony overgrowth covering the interlocking screws/pegs were noticed. No bone abnormalities related to blocking screws were observed.
Conclusions: Bone abnormalities at the interface of telescoping nail parts were seen in the majority of Stryde nails, but only very rarely with Fitbone or Precice nails. Of clinical relevance, the low prevalence of radiographic changes at the junctional interface of 242 evaluated Fitbone and 98 evaluated Precice nails at the time of nail removal does not seem to warrant clinical concerns.
Lower Limb Deformity
OP-114
Two-stage lengthening with reuse of a single intramedullary telescopic nail in patients with achondroplasia
Javier Alonso1, María Galán-Olleros1, Carlos Miranda1, Rosa M. Egea-Gámez1, Ignacio Martínez-Caballero1, Angel Palazon Quevedo1
1Orthopaedic Surgery and Traumatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain
Introduction and Objective: Patients with achondroplasia may benefit from limb-lengthening surgery with telescopic intramedullary nails (TIMNs). However, the 5-cm maximum length of the nails used in these patients in their original design may be insufficient. The aim of this research is to analyze the outcomes and complications after reusing the same TIMN for a second consecutive 5-cm lengthening in achondroplasia patients.
Materials and Methods: Retrospective study of 26 bones (16 femurs and 10 tibias) in 9 patients with achondroplasia treated for bilateral 2-stage sequential lengthening reusing the same TIMN. On completion of a first stage of 5-cm of elongation, the nail was unlocked, retracted, and re-locked; a second stage of 5-cm of distraction followed. Radiologic and clinical parameters were measured, and complications were recorded.
Results: The median age of patients at first surgery was 13.54 (12.9-16.3) years. The median preoperative height was 121 (117.5-127) cm, and the median healing index was 18.12 (14.5-32.8) and 26.96 (23.3-31.6) days/cm, while time to weight bearing was 185.5 (144.8-308.5) and 242.5 (208.5-293.8) days for femurs and tibias, respectively. Major complications included 3 cases of moderate ankle equinus, 2 cases of hardware failure (failure to re-lengthen), 2 premature consolidations, 1 common peroneal neurapraxia and 2 valgus deformities. Femoral procedures had significantly fewer complications than tibial interventions (7vs.15, p = 0.03), whereas patients who underwent lengthening of both the femur and tibia did not have significantly higher complication rates (14 vs. 8, p = 0.6).
Conclusions: This is the first report of lower-limb lengthening in a series of patients with achondroplasia using TIMN with nail reuse to re-lengthen the bone. The complication rate found is acceptable, among which, potential damage to the internal lengthening mechanism must be considered, though this complication can usually be easily resolved. Overall, nail reuse seems advisable in cases where bone elongation is indicated, and the size and design of the nail limits the extent of lengthening.
Lower Limb Deformity
OP-115
3D printed cutting guides for lower limb deformity correction in the young population
Roy Gigi1, Yair Gortzak1, Eran Golden1, Ronnie Gabay1, Netta Rumack1, Moshe Yaniv1, Solomon Dadia1, Eitan Segev1
1Tel-Aviv Souraski Medical Center, Tel Aviv-Yafo, Israel
Introduction and Objective: Patient-specific instruments (PSI) and surgical-guiding templates are gaining popularity as a tool for enhancing surgical accuracy in the correction of oblique bone deformities Three-dimensional virtual surgical planning technology has advanced applications in the correction of deformities of long bones and enables the production of 3D stereolithographic models and PSI based upon a patient’s specific deformity. We describe the implementation of this technology in young patients who required a corrective osteotomy for a complex three-plane (oblique plane) lower-limb deformity.
Materials and Methods: Radiographs and computerized tomographic (CT) scans (0.5 mm slices) were obtained for each patient. The CT images were imported into post-processing software, and virtual 3D models were created by a segmentation process. Femoral and tibial models and cutting guides with locking points were designed according to the deformity correction plan as designed by the surgeon. The models were used for preoperative planning and as an intraoperative guide. All osteotomies were performed with the PSI secured in the planned position.
Results: A total of 17 patients (9 males and 8 females, average age 14.7 years [range 8-24]) comprised the study group. All of the PSI were excellent fits for the planned bone surfaces during surgery. The osteotomies matched the preoperative planning simulation and allowed for easy fixation with pre-chosen plates. No intra- or postoperative complications were encountered. Surgery time was shortened (101 minutes) and intraoperative blood loose was less compared to historical cases. Clinical and radiographic follow-up findings showed highly satisfactory alignment of the treated extremities in all 17 patients.
Conclusions: The use of 3D-printed models and patient-specific cutting guides with locking points increases accuracy, shortens procedure time, reduces intraoperative blood loss, and improves the outcome of osteotomies in young patients with complex oblique bone deformities.
Lower Limb Deformity
OP-116
Lower limb lengthenings for congenital and acquired deficiencies using external fixation combined with flexible intramedullary nailing: A multicenter EPOS study
Dmitry Popkov1, Szymon Pietrzak2, Alexandre Antonov1, Tomasz Parol2, Mikan Lazovic3, David Podeszwa4, Arnold Popkov5
1National Ilizarov Center, Kurgan, Russian Federation, 2Department of Orthopaedics, Children’s Orthopaedics and Traumatology Medical Center of Postgraduate Education, Otwock, Poland, 3Orthopaedic Department, Children’s University Hospital, Belgrade, Serbia, 4Department of Orthopaedics, Texas Scottish Rite Hospital for Children, Dallas, USA, 5National Ilizarov Center, Russian Federation
Introduction and Objective: The aim of this EPOS approved multicenter prospective study was to analyze the outcomes of bone lengthening by external fixator associated with flexible intramedullary nailing (FIN) in congenital and acquired lower limb length discrepancy (LLD). Hypothesis: Hydroxyapatite (HA) -coated FIN enables reduced External Fixation Index (EFI) in lower limb lengthening in comparison to titanium FIN.
Materials and Methods: This study included 70 patients with congenital LLD (mean age of 12.6 years) and 44 patients (mean age of 14.9 years) operated on for femoral or tibial lengthening. Titanium non-HA-coated FIN (Ti-FIN, 65 cases) or HA-coated FIN (HA-FIN, 49 cases) were used.
Results: The mean EFI of groups compared for Ti-FIN vs. HA-FIN were not significantly different for both congenital and acquired LLD. In congenital LLD, significant positive correlation between the ratio “nail diameter/medullary shaft diameter” and EFI in tibial bifocal Ti-FIN lengthening, and a significant positive correlation between age and EFI for femoral Ti-FIN lengthening, tibial monofocal and bifocal HA-FIN lengthening were revealed. In acquired LLD, a positive correlation between the “Nail diameter/inner distance between cortices at osteotomy site” ratio and EFI in tibial lengthening was revealed. The nail types and the “nail diameter/medullary canal diameter” ratio interact and have significant simultaneous effect on EFI in femoral lengthening. There was a statistically significant negative correlation between nail diameter and fracture occurrence after frame removal. A ratio of less than 0.15 likely does not ensure necessary stability.
Conclusions: Both Ti-nail and HA-coated nail lengthening provide good outcomes for lengthening procedures and ensure reduced EFI. In disorders which were not associated with abnormal bone, there are no differences with regards to EFI using HA-FIN or Ti-FIN. The ratio of “elastic Ti-nail diameter/medullary canal diameter at narrowest site” less than 0.15 seems to be associated with higher risk of fracture at the lengthening site after frame removal.
Lower Limb Deformity
OP-118
Longterm follow up of retrograde femoral approach in lengthening: Is there an impact for the knee?
Andreas Krieg1, Chao Dong1, Schmid Marc1, Harder Dorothee2, Donners Ricardo2
1Orthopaedic Department, University Children’s Hospital Basel, Basel, Switzerland, 2Department of Radiology, Universitätsspital Basel, Basel, Switzerland
Introduction and Objective: Retrograde femoral approach is an established technique for implantation of nails for leg lengthening. We clinically and radiologically analyzed the longterm impact (> 10 years) to the knee after leg lengthening via a retrograde femoral approach in comparison to the non-operated contralateral knee.
Materials and Methods: In this prospective single-center study 13 patients with an average age of 17.4 years (15.3-19.5) were included who had unilateral retrograde femoral lengthening with motorized nail performed at least 10 years prior to the initial operation. Patients were clinically examined (gait, leg length, scars) and analysed with the SF 36, ISKD- and Lysholm Score. MRI (3 Tesla) of both knees of all patients were performed. The MRI of the contralateral knee of each patient served as a control.
Results: The long-term clinical results and score analysis showed, that all patients were pain free and showed full range of motion without deficiency in comparison to the contralateral knee. None of the postoperative or healthy knees showed signs of chronic synovitis. All postoperative knees showed fibrosis of Hoffa’s fat pad, while no fibrosis was found in the control group. At least moderate to severe cartilage defects (Grade II-IV) of the trochlear groove were found in all postoperative knees at the original entry point. 10 of 13 patients showed atrophy of the medial and lateral vastus muscle on the postoperative side in comparison to the healthy side caused by the lengthening procedure.
Conclusions: Retrograde femoral lengthening with a motorized nail about retrograde femoral approach can be associated with cartilage defects at the entry point, arthrofibrosis at Hoffa and atrophy of the quadriceps muscle caused by the lengthening procedure. Without corresponding clinical impairment these findings may be normal in long-term follow up, but the surgeon has to inform the patient in front of this surgical approach.
Study Group Neuromuscular
Free Papers
SG-01
Concurrent hip dysplasia and scoliosis in children with cerebral palsy: Should we fix the hip or spine first?
Michael W. Shrader1, Ali Asma1, Armagan Can ulusaloglu1, Kenneth Rogers1, Freeman Miller1, Jason Howard1, Mutlu Cobanoglu1, Suken Shah1
1Nemours Children’s Hospital, Delaware, Wilmington, United States
Introduction and Objective: Children with Cerebral Palsy (CP) frequently develop both neuromuscular hip dysplasia and scoliosis. The question as to whether the hip or spine should be addressed first remains controversial, with the majority of evidence being ‘expert opinion’. The purpose of this project was to determine the impact of posterior spinal fusion (PSF) on the change in hip displacement for children with CP.
Materials and Methods: This was an IRB approved retrospective cohort study. Inclusion criteria included children with CP (18 and less), GMFCS IV and V, undergoing PSF at a single tertiary care children’s hospital with appropriate radiographic follow up. The primary outcome was the change in hip displacement as quantified by the Migration Percentage (MP); change in MP before and after PSF was measured and compared using Welch’s t-tests (significant p < 0.05), for a minimum of three years post-PSF or until hip reconstruction was performed. Tri-radiate cartilage status and pelvic obliquity correction were analyzed with multivariate analysis.
Results: 67 patients were included for analysis, with a mean age of 12.5 (±2.3). The mean Cobb angle of the major curve was 76.9° (±23.12), and the mean preoperative pelvic obliquity was 20.72° (±12.12). There was no statistically significant change in MP following PSF from a mean preoperative value of 41.02 (± 27.26), to a mean postoperative value of 41.32 (±29.7), p = 0.760. The mean follow-up time was 48.9 months (±32.06). Multivariate analysis showed that tri-radiate cartilage status (p = 0.52) and the severity of pelvic obliquity (p = 0.10) did not statistically impact the change of MP following PSF.
Conclusions: Scoliosis correction surgery did not affect the progression of hip displacement in children with CP, regardless of pelvic obliquity correction or triradiate status. These results could impact the decision of whether to address the spine before hip reconstruction in children at risk for needing both procedures.
Study Group Neuromuscular
Free Papers
SG-02
Kinematic parameters may differentiate between idiopathic and neurologic toe-walking
Martin Svehlik1, Andreas Habersack1, Tanja Kraus1, Stefan Fischerauer1
1Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria
Introduction and Objective: The diagnosis “idiopathic toe-walking” (ITW) is one of exclusion. The differentiation between ITW and other forms of toe-walking associated diseases, especially children with cerebral palsy (CP), is often clinically difficult. The present study aims to compare gait patterns and answer the question whether 3D gait analysis can discriminate between these groups.
Materials and Methods: We conducted a retrospective controlled stratified cohort study. Eleven children (mean age 8.9 ± 2.4 years) with clinical diagnosis of bilateral ITW were 1:1 matched to spastic CP (GMFCS I-II) (8.4 ± 2,4 years) and a typically developing peer (control, 9,3 ± 2,4 years). Stratification was achieved by matching the children in terms of maximal dorsiflexion during gait, age, and gender. We collected kinematic and kinetic data. Pairwise comparison between ITW and CP was performed as for non-parametric distributed data using Wilcoxon signed-rank test. To define the discriminatory ability non-parametric receiver operating characteristics (ROC) including area under the curve (AUC), sensitivity and specificity parameters were calculated.
Results: We found kinematic and kinetic parameters having a high discriminatory power showing high values for AUC, sensitivity and specificity to distinguish between ITW and CP groups [e.g. sagittal knee angle at initial contact (AUC 0.8; sensitivity 91%; specificity 73%), time point of the maximal knee flexion (AUC 0.96; sensitivity 95%; specificity 86%), foot progression angle (AUC 0.82; sensitivity 82%; specificity 73%) and the ankle power during stance phase (AUC 0.84; sensitivity 82%; specificity 86%)].
Conclusions: The strength of this study is a high discriminatory power between ITW and CP toe-walking groups. The results verify that clinical gait analysis can be used as an effective method to differentiate between idiopathic and neurologic toe-walkers. Described kinematic parameters are easy to examine even without high-tech equipment and therefore directly transferable to the every-day praxis.
Study Group Neuromuscular
Free Papers
SG-03
Somatosensory profiles in children and adolescents with cerebral palsy
Johanne Villars Jørgensen1, Mads U. Werner2, Josephine S. Michelsen3, Christian Wong1
1Department of Orthopedic Surgery, Children, Hvidovre Hospital, Hvidovre, Denmark, 2Department of Anesthesia, Pain and Respiratory Support, Multidisciplinary Pain Center 7612, Copenhagen, Denmark, 3Danish Multiple Sclerosis Center, Glostrup, Denmark
Introduction and Objective: Chronic pain is one of the major determinants for quality of life, however an overlooked clinical problem in children and adolescents with cerebral palsy (CP). To better understand the underlying pain mechanisms and to facilitate adequate treatment, the somatosensory profiles were investigated with quantitative sensory testing (QST).
Materials and Methods: All subjects in this cross-sectional explorative study were recruited from and tested at the outpatient orthopedic clinic. The QST was preceded by assessments of reaction time and performed on the most affected limb or a randomized limb for controls. The QST consisted of tests for detection (warmth WDT, cool CDT, mechanical MDT and vibration VDT) and pain thresholds (heat HPT, pressure PPT and mechanical MPT), two dynamic tests (wind-up WUR and allodynia DMA) and conditioned pain modulation (CPM).
Results: The study included 51 subjects in total, 25 with CP (9 and 16 w/o chronic pain), and 26 without CP (14 and 12 w/out chronic pain). Subjects without CP without chronic pain stating as controls. Reaction times were longer in subjects with CP (p = 0.001). Thermal hypoesthesia (WDT: p = 0.03, CDT: p = 0.03) and a trend for mechanical hypoesthesia (MDT: p = 0.05) were demonstrated in subjects with CP. When rating pain during heat pain (HPT) more subjects with CP rated the pain intensity as high (13/25 vs. 2/12, p = 0.01) and fewer registered increasing pain in wind-up (WUR, 6/25 vs. 7/12, p = 0.04). Subjects without CP with chronic pain demonstrated thermal hypoesthesia (WDT: p = 0.008, HPT: p = 0.02) and more subjects rated the pain intensity as high (9/14 vs. 2/12, p = 0.01). Compared to subjects with CP they demonstrated heat hypoalgesia (HPT: 44.2°C vs. 40.5°C, p = 0.04).
Conclusions: Somatosensory profiles in subjects with CP demonstrated similarities regardless of the pain phenotype. Further sensory studies are warranted examining the pathophysiological mechanism of pain in children and adolescents with CP.
Study Group Neuromuscular
Free Papers
SG-04
The importance of restoring a heel-toe gait pattern in patients with unilateral spastic cerebral palsy: The correlation between femoral anteversion and asymmetrical hip internal rotation
Michèle Kläusler1, Enrico De Pieri1, Rosa Visscher1 2, Elke Viehweger1, Reinald Brunner1
Introduction and Objective: A common problem in patients with spastic cerebral palsy (CP) is equinus gait and later in childhood, if left untreated, development of hip internal rotation (IR), flexion and adduction problems of the affected leg. The aim of this retrospective cross-sectional study is to evaluate the effect of restoring heel-toe gait, through use of a functional orthosis on passive hip IR as well as the influence of femoral anteversion (FA).
Methods: To achieve heel-toe gait, the affected foot was kept in an anatomically correct position through use of orthosis, if necessary with compensatory heel rise. Two groups were formed. Group 1 [n = 54; age 11.8 y (± 5 y); GMFCS level I = 52, II = 2]: patients with a heel-toe gait, wear of orthosis ≥ 8 h/day for ≥ 1 year. Group 2 [n = 14; age 10.38 y (± 5y); GMFCS level I = 13, II = 1]: patients with toe-walking pattern, use of orthosis ≤ 8 h/day for ≥ 1 year. Passive hip IR and FA were clinically assessed.
Results: We found a mean difference of FA between the two legs in group 1 of 0.33° (± 6.1°) and group 2 1° (± 5.68°). The groups showed no significant difference (p = 0.74). Patients in group 1 had almost symmetrical IR [1.5° (± 9.6°)]; while patients in group 2 had an increase of asymmetrical IR [10.4° (± 7.5°)]. The groups showed a significant difference (p = 0.001).
Conclusions: Our clinical findings show no correlation between FA and asymmetrical increase of hip IR in patients with unilateral spastic CP. The results are in line with our observation, that treating the primary biomechanical problem by achieving a heel-toe gait in young age of CP patients might prevent the development of deformity. Further prospective studies are necessary.
Upper Limb
OP-119
Vascularized palmar intermetacarpal flap for skin graftless syndactyly release: Anatomical study and report of 41 cases
Francisco Soldado1, Paula Diaz-Gallardo2, Jorge Giménez Knorr3
1iPULMi (International Pediatric Upper Limb and Microsurgery Inst itute), POS, Barcelona, Spain, 2Hospital de la Santa Creu i Sant Pau, POS, Barcelona, Spain, 3iiTOP, POS, Barcelona, Spain
Introduction and Objective: Skin-graftless techniques for syndactyly release using dorsal flaps result in a decrease of complications but in worse cosmetic results as a result of the dorsal scars. We analyse the outcomes of a novel skin-graftless technique using a vascularized intermetacarpal palmar flap for syndactyly release.
Materials and Methods: An anatomical study of cutaneous perforators in 10 latex-injected fresh upper limbs. A flap was performed in distal half of the 2nd to 4th intermetacarpal space. Retrospective analysis of children treated between February 2017 and June 2020. We assessed the following parameters in 52 web spaces of 45 patients: grading of web creep (Withey grading), Vancouver Scar Scale, assessment of complications and functional and cosmetic parental satisfaction using a 4-point Likert-type ordinal scale.
Results: A mean of 2.7 perforators per flap were found in every intermetacarpal space arising from the common or proper digital arteries. 45 children (25 girls, 25 right-sided) of mean age 4 years 4 months and mean follow-up 24 months were assessed. In 30 patients the syndactyly involved the third web space, in 11 cases the fourth and in 4 cases the second. Syndactylies were classified as partial simple in 20 cases, complete simple in 11 and complex in 14 cases. Two patients developed a severe digital keloid and were removed from the study. According to Withey Grading of web creep, 40 cases was graded 0 and 3 cases was graded 1. All patients were extremely satisfied with the palmar scar while all except one (very satisfied), with the digital scar.
Conclusions: Skin graftless syndactyly release technique using a volar intermetacarpal flap seems reliable and results into excellent cosmetic results compared to skin-graftless using dorsal flaps.
Upper Limb
OP-120
Evaluation of 3D printing options in posttraumatic complex elbow reconstruction in children and adolescents
Tobias Dust1, Julian Elias Henneberg1, Milad Farkhondeh Fal1, Kristofer Wintges2, Till Orla Klatte1, S. John Ham3, Konrad Mader1
1UKE, Division Hand, Forearm and Elbow Surgery, Hamburg, Germany, 2UKE, Department of Pediatric Surgery, Germany, 3Department of Orthopaedic Surgery, Center for MO at OLVG, Amsterdam, The Netherlands
Introduction and Objective: Corrective osteotomies at the elbow are difficult procedures. With 3D planned and printed options a significant advantage over traditional methods could be already shown. This study examines the outcome of 3D printing in the context of presurgical planning of complex elbow deformities (CED) in a tertiary reference center.
Results: 25 patients of the 3D-printed group (11 males and 14 female, average 18, ± 5 years) and 40 patients of the control group (22 male and 18 female, average 17, ± 8 years) were included in this study. After 3 months the patient satisfaction was significantly higher in the 3D-printed group (VAS 8 ± 1 vs 6 ± 3 in the 2D-group, p < 0,05) with less operative time (3D: 105 min ± 47, 2D 125 ± 65, p < 0.05), and less fluoroscopy exposure (3D: 7.32 cGycr ± 7.31 vs. 2D 13.25 ± 9.23, p < 0.05). No significant difference was found in q-DASH and radiographic analysis, although there was a tendency in favor of the 3d planning group.
Conclusions: 3D printing is a reliable planning tool, helps in communication/counseling, reduces resources (operative time, fluoroscopy exposure) compared to 2dimensional planning. Although patient reported outcome and a significant impact on accuracy could not be demonstrated, we have put this tool in constant use.
Upper Limb
OP-121
Does older age and glenoid dysplasia affect outcome of soft tissue release and tendon transfer in shoulders with brachial plexus birth palsy?
Gholamhossain Shahcheraghi1, Mahzad Javid1
1Orthopaedy, Shiraz University of Medical Sciences, Shiraz, Iran
Introduction and Objective: The shoulder involvement in brachial plexus birth palsy (BPBP) is common and the adduction,internal rotation contracture deformity often requires some form of surgical treatment. There are very few long-term reports on release of contracted muscles and tendon transfers, especially in older children.We are reporting the single center results of such a surgery with detailed outcome analysis.
Materials and Methods: The prospectively-collected data from BPBP cases who had undergone contracture release and tendon transfer, were retrospectively studied and examined. The new Mallet and functional scores were compared with the original data forms and then analyzed. The radiographic evidence of glenoid dysplasia, and its correlation with age and functional outcome was assessed.
Results: 82 cases with surgery at mean age of 9.5 ± 5.09 years, and follow-up of 8 ± 3.8 (3 - 20) years entered the study. 56% of cases had 7 to 20 years of age at surgery. Fifty-four (66%) patients had only shoulder surgery, and 28 (34%) required additional reconstructive surgeries for hand and wrist. Moderate to severe glenohumeral dysplasia (GHD) was present in 38%. The preoperative Mallet score of 10.6 ± 2.97 improved to 19.3 ± 3.39. (p < 0.001). 81%of patients showed improvement in” reaching face” functions, 71% in “above head” functions and 74% in” midline functions”. The cases with lack of improvement in midline function mostly belonged to pan-plexus injuries. Noticeable subjective and objective improvement was also observed in cases with glenohumeral dysplasia (GHD) in their Mallet and functional scores (p value < 0.001). The improvement in function and subjective satisfaction of 92% was observed irrespective of age at surgery.
Conclusions: Soft tissue release and tendon transfer for BPBP shoulder can improve function and limb appearance even in older children and young adults, and even in the presence of GHD.
Upper Limb
OP-122
Estimating skeletal maturity using wrist radiographs during pre-adolescence: The epiphyseal:metaphyseal ratio
Lauren Huang1, Raymond Liu2, Ryan Furdock3, Naveen Uli4
1Case Western Reserve University School of Medicine, Cleveland, USA, 2Division of Pediatric Orthopaedics, Rainbow Babies and Children’s Hospital, Cleveland, USA, 3Department of Orthopaedics, University Hospitals Cleveland Medical Center, Cleveland, USA, 4Center for Diabetes and Endocrinology, Akron Children’s Hospital, Akron, USA
Introduction and Objective: Though skeletal maturity (SM) is most relevant during adolescence, it is also useful in treating younger patients. Currently, a quick and accurate method of estimating SM in pre-adolescents using wrist radiographs is lacking.
Materials and Methods: Serial AP wrist radiographs taken at historical growth study visits leading up to the chronological age (CA) associated with 90% of final height (an enhanced SM standard compared to peak height velocity) were analyzed in 102 children. A total of 7 epiphyseal:metaphyseal radiographic parameters were measured: epiphyseal and metaphyseal widths of five physes (distal radius, distal ulna, and first, third and fifth metacarpals) and the ulnar and radial styloid heights. Stepwise linear regression and generalized estimating equation analyses were used to produce a SM estimation model incorporating demographics (CA and sex) and the two epiphyseal:metaphyseal ratios most highly correlated with SM. The skeletal age (SA) estimation accuracy of this new demographics + epiphyseal:metaphyseal ratios model was compared to two others: Greulich and Pyle (GP) alone, and GP after optimization with demographics.
Results: 275 left AP hand-wrist radiographs from 56 girls (4-13 years) and 46 boys (3.8-15 years) were included. All radiographs had an associated CA, sex, and GP skeletal age determined by an experienced pediatric endocrinologist. The demographics + ratios model had better prediction accuracy than GP only and GP with demographics (0.44, 0.87 and 0.47 year mean discrepancy from actual SA, p <.05 for both comparisons). There was no significant difference in the rate of outlier SA estimates between the demographics + ratios model and the demographics + GP model (5.9% versus 8.4%, p = 0.12, see Table 1).
Conclusions: Measurement of epiphyseal:metaphyseal ratios of the first and third metacarpals allows for improved SM estimation compared to the GP technique when combined with demographics, offering a clinically applicable method for estimating pre-adolescent SM.
Comparison of skeletal maturity model performance
GP only
Age + Sex + GP
Age + Sex + Ratios
Average skeletal age estimation discrepancy (years)
Outlier = skeletal maturity estimate > 1 year off from true skeletal age; p values are all in comparison to Age + Sex + Ratios, bold = statistically significant
Upper Limb
OP-123
Carpal tunnel syndrome and finger deformities in children with mucopolysaccharidoses and mucolipidoses: A retrospective review of 52 cases
Introduction and Objective: Carpal tunnel syndrome (CTS) in children is uncommon and when treating such patients, a cause should be sought, in particular lysosomal storage disorders. The objective of this study was to characterise CTS and finger deformities in children with mucopolysaccharidoses (MPS), and to assess their postoperative clinical and electromyogram outcomes.
Materials and Methods: This single centre retrospective study was conducted from 1999 to 2018 and included 52 consecutive children with MPS who underwent CTS surgery after a CTS confirmed by an EMG. Open surgery was performed for the section of the transverse carpal ligament, and combined if needed with epineurotomy, flexor tenosynovectomy or opening of A1 and/or A3 finger pulleys to treat finger deformities depending on the clinical examination.
Results: Mean follow-up was 12 years. Average age at diagnosis of MPS was 2.3 years and mean age at surgery was 5.2 years. All but one of the surgeries were bilateral. Digital flexion contracture on at least one finger was found in 23 children. Trigger fingers were present in 10 cases. Surgical neurolysis was performed in all cases, combined with epineurotomy (50%) and flexor tenosynovectomy (73%). Of the 22 patients who had objective preoperative clinical signs of median nerve compression, 5 were no longer painful or had no more nocturnal awakenings while 2 patients remained painful. The EMG was normalised with full recovery in 78% of patients. Four patients had discrete sequelae of sensory and/or motor abnormalities stable over time without any clinical complaints. Ten patients suffered recurrence, 8 of whom required further surgery.
Conclusions: Screening for carpal tunnel syndrome is essential for the follow-up of children mucopolysaccharidoses. Surgical treatment should be carried out early with follow-up by EMG to detect recurrence.
Upper Limb
OP-124
Transposition of distal part of pectoralis major to biceps brachii in children with arthrogryposis
Olga Agranovich1, Petrova Ekaterina1, Sergey Batkin1
1H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery of the Ministry of Health of the Russian Federation, Arthrogryposis, Pushkin, Russian Federation
Introduction and Objective: One of the main problems that limit or do impossible self-ability of patients with arthrogryposis is the lack of active elbow flexion due to hypoplasia (or aplasia) of the flexors of the forearm and, especially m. biceps brachii.
Materials and Methods: From 2011 to 2020 we carried out restoration of elbow active flexion by partial monopolar transposition of the pectoralis major muscle to biceps brachii in 34 children with arthrogryposis (39 upper limbs). The muscle autograft included a fragment of the fascia of m. rectus abdominis. We performed clinical and EMG estimation in patients before and after operation.
Results: The follow-up results were estimated from 6 to 99 months (44.53 ± 31.72) post operation. The mean age of patients was 6.24 ± 4.24 years. The active postoperative elbow flexion was 0°-120° (71.94 ± 33.40). The passive postoperative elbow flexion didn’t change and was 90°-130° (104.12 ± 12.40). Muscle strength after operation was estimated as grade 2-5. Limitation of elbow extension was in 30 cases (76.9%) from 0° to 40° (21.70 ± 12.27) without problems in daily living. Positive results were in 15 cases (38.5%), satisfactory in 8 (20.5%, poor in 16 (41%).
Conclusions: This study showed that our technique of the partial monopolar transfer of pectoralis major to biceps brachii allows to restore sufficient flexion of the forearm and improve self-ability without forming severe elbow flexor contractures in more than half of cases in patients with arthrogryposis.
Upper Limb
OP-125
Radial club hand treated by ulnarization generation 3: The new centralization
Jaroslaw Deszczynski1, Tomasz Albrewczynski1, Claire Shannon2, Dror Paley2
1Paley European Institute, Warszawa, Poland, 2The Paley Orthopedic & Spine Institute, West Palm Beach, USA
Introduction and Objective: Radial Club Hand (RCH) is a rare condition occurring in 1:30,000 to 1: 100,000 live births. It is often associated with radial ray deficiency. Currently centralization and radialization are the most common surgical approaches to treat RCH despite many studies showing recurrence of the radial deviation in both techniques. Recurrent deformity from centralization and radialization led to the development in 1999 of a new technique called ulnarization. Patients treated with previous generations of ulnarization developed a bump related to the ulnar head becoming prominent on the radial side. Current modified version includes centralization of the wrist over the ulna.
Materials and Methods: Between 2019 and 2021, 24 radial club hands in 19 patients were surgically corrected with modified version of ulnarization including centralization of the wrist over the ulna. There were 13 right and 11 left hands. Fourteen were unilateral and 5 bilateral. The mean age at surgery was 22.1 months (range 17 - 52 mos.). All postoperative complications from surgery were recorded. Radiographic measurements were made of the hand-forearm angle (HFA), ulnar bow angle and the ulnar length before and after surgery.
Results: All 19 patients presented HFA correction. Significant ulna growth was observed in all cases. There were no recurrent radial deviation deformities more than 15° of HFA.
Conclusions: This new version of ulnarization show satisfactory results and may solve the problem of the ulna growing past the carpus creating a prominent ulnar bump. It also has shown that it is safe and reproducible procedure.
Tumours / Miscellaneous
OP-126
Treatment of aneurysmal bone cysts in the proximal femur in 85 children and adolescents: Retrospective multi-center analysis
Lizz van der Heijden1, Thom van Geloven1, Dietmar Dammerer2, Masood Umer3, Kevin Doering4, C Soto-Montaya5, Mohamed Mesregah6, Philipp Scheider7, Valentino Coppa8, Tanja Kraus9, M Haara10, Giovanni Beltrami11, Minna Laitinen10, Domenico Campanacci12, Pieter-Bas de Witte1, Michiel van de Sande1
1Orthopaedic Surgery, Leiden University Medical Center, Leiden, The Netherlands, 2Medizinische Universität Innsbruck, Innsbruck, Austria, 3Aga Khan University Hospital, Karachi, Pakistan, 4Medical University of Vienna, Wien, Austria, 5National Cancer Institute - ESE, Bogotá, Colombia, 6Orthopaedic Surgery, Faculty of Medicine, Menoufia University, Egypt, 7Orthopaedic Surgery, Medical University of Vienna, Wien, Austria, 8Orthopaedic Surgery, Marche Polytechnic University, Ancona, Italy, 9Department of Orthopedics and Traumatology, Graz, Austria, 10Orthopaedic Surgery, Helsinki University Hospital, Helsinki, Finland, 11Pediatric Orthopaedics, Azienda Ospedaliero Universitaria Meyer, Florence, Italy, 12Orthopaedic Surgery, Azienda Ospedaliero Universitaria Careggi, Florence, Italy
Introduction and Objective: Aneurysmal bone cysts (ABC) are rare, pediatric and adolescent benign cystic bone tumors. Proximal femoral ABCs may require different treatment because of increased risk for (impending) pathologic fractures. Consensus regarding optimal treatment is lacking, since few reports on this specific localization have been published. We retrospectively reviewed treatment and outcomes for proximal femoral ABC, including re-operations and fractures after index-procedure, revision-free survival and time until full weightbearing.
Materials and Methods: All consecutive pediatric patients with proximal femoral ABC from eleven centers were included (2000-2021). Patient demographics, diagnostics, primary treatments, and re-operations were evaluated. Index-procedures were categorized as wait-and-see, percutaneous/open procedures and stand-alone osteosynthesis.
Results: Eighty-five patients with ABC were included (mean age 10.4 years (± SD3.97), n = 60 male). Mean follow-up was 5.3 years (± SD4.5). Index treatment was wait-and-see (n = 4), percutaneous procedures (n = 22), open procedures (n = 39) or stand-alone osteosynthesis in 21 patients. Mean number of re-operations performed in follow-up: wait-and-see 1.5 (range = 0-3), percutaneous 0.6 (range = 0-4), open procedure 0.7 (range = 0-8) and stand-alone osteosynthesis 0.3 (range = 0-3) (p = 0.30). (Re-) operations for (impending) fractures were performed in 2/4 wait-and-see, 3/22 percutaneous, 8/39 open procedure and 4/21 stand-alone osteosynthesis patients, comprising 46% of all open re-procedures. Two- and 5-years revision-free survival was 76.4% and 72.3%. Median time until full weightbearing allowed for wait-and-see was 6 weeks, percutaneous 6, open procedure 13 and for stand-alone osteosynthesis 6 (n = 59, p = 0.14).
Conclusions: After initial wait-and-see policy for proximal femoral ABCs, fractures were often seen and (re) interventions indicated. Therefore, wait-and-see may not be recommended as primary treatment. Revision-free survival strongly declines in the 2-to-5 year interval, corresponding with the aggressive local clinical behavior of ABCs. Mean time until allowed full weightbearing was shorter and required open re-interventions were less for percutaneous treatment compared to open treatment in ABCs.
Tumours / Miscellaneous
OP-127
Efficacy and safety of tranexamic acid in resection and endoprosthetic reconstruction of distal femoral osteosarcomas in children: A retrospective cohort study
Bulent Erol1, Omer Sofulu1, Ozer Ozturk1, Murat Polat1, Omer Buyuktopcu1, Mehmet Deniz Kesimer1
1Department of Orthopaedic Surgery and Traumatology, Marmara University School of Medicine, Istanbul, Turkey
Introduction and Objective: This study aimed to investigate the effect of intravenous tranexamic acid (TXA) on blood loss and transfusion rates in children who underwent resection and endoprosthetic reconstruction of distal femoral osteosarcomas.
Materials and Methods: The medical records of 56 patients who underwent resection and endoprosthetic reconstruction for distal femoral osteosarcomas between 2017 and 2019 were retrospectively reviewed. Patients were divided into two groups: Group 1 consisted of 25 patients (11 male and 14 female, mean age 15.2 ± 3 years) who received preoperative 15mg/kg intravenous TXA, and Group 2 consisted of 31 control patients (18 male and 13 female, mean age 14.3 ± 2.6 years) who did not receive TXA.
Results: The mean total blood loss was lower in intravenous TXA group (1247.5 ± 300.9 mL) when compared to control group (1715.7 ± 857.0 mL) (p = 0.018). The mean intraoperative blood loss in intravenous TXA group (386 ± 109 mL) was lower than that in control group (977.4 ± 610.7mL) (p < 0.001). Postoperative drain output at 24- and 48-hours was 198.0 ± 61.8 and 72.4 ± 27.4 mL in intravenous TXA group respectively, and was low compared to 268.4 ± 118.2 and 117.1 ± 67.8 mL in control group (p = 0.028 and p = 0.006). The rate of patients requiring transfusion was significantly lower in intravenous TXA group (56%) than in control group (83.9%). Preoperative and postoperative 6-, 24-, and 72-hours Hb and Htc differences were significantly lower in intravenous TXA group [ (-1.7 ± 1.8 gr/dL p < 0.001; -2.0 ± 1.5 gr/dL p < 0.001; -2.3 ± 1.7 gr/dL p < 0.001, for Hb), (-5.7 ± 4.6, p < 0.001; -6.9 ± 4.0, p < 0.001; -9.6 ± 9.1, p < 0.001, for Htc)].
Conclusions: We conclude that administration of intravenous TXA reduces intra- and postoperative blood loss, transfusion rates, and hospital stay in resection and endoprosthetic reconstruction of the distal femoral osteosarcomas in children.
Tumours / Miscellaneous
OP-128
Treatment of unicameral bone cysts in the proximal femur in 89 children and adolescents: Retrospective multi-center study
Thom van Geloven1, Lizz van der Heijden1, Dietmar Dammerer2, Masood Umer3, Kevin Doering4, C Soto-Montaya5, I Badr6, Philipp Scheider7, Tanja Kraus8, M Haara9, Giovanni Beltrami10, Minna Laitinen9, Domenico Campanacci11, Pieter-Bas de Witte1, Michiel van de Sande1
1Leiden University Medical Center (LUMC), Leiden, The Netherlands, 2Tirol Kliniken GmbH, Innsbruck, Austria, 3Aga Khan University Hospital, Karachi, Pakistan, 4University of Vienna, Wien, Austria, 5National Cancer Institute - ESE, Bogotá, Colombia, 6Faculty of Medicine, Menoufia University, Egypt, 7Medical University of Vienna, Wien, Austria, 8Department of Orthopedics and Traumatology, Graz, Austria, 9University of Helsinki, Helsinki, Finland, 10University Hospital Meyer, Firenze, Italy, 11Careggi University Hospital, Firenze, Italy
Introduction and Objective: Unicameral bone cysts (UBC) are one of the most prevalent benign cystic tumor-like lesions in children. Proximal femoral UBCs may require different treatment, because of increased risk of (impending) pathologic fractures. With limited literature on this specific localization, consensus regarding optimal treatment is lacking. We retrospectively reviewed treatment and outcomes for proximal femoral UBCs, including re-operations and fractures after index-procedure, revision-free survival and time until full weightbearing.
Materials and Methods: All consecutive pediatric patients with proximal femoral UBC (2000-2021) from eleven centers were included. Demographics, primary treatments, complications and re-operations were evaluated. Index-procedures were categorized as wait-and-see, percutaneous and open procedures and stand-alone osteosynthesis.
Results: Eighty-nine patients with UBC (mean age 9.5 years (± SD3.81), 68 males) with mean follow-up of 5.3 years (± SD4.5) were included. Index treatment was wait-and-see (n = 7), percutaneous (n = 19), open procedures (n = 52) or osteosynthesis (n = 11). Pathological fractures at diagnoses were reported in 14.3% wait-and-see, 26.3% percutaneous, 30.8% open and 54.5% osteosynthesis. Mean number of open re-operations performed were 0.29 (range = 0-1) for wait-and-see, 0.95 (range = 0-4) percutaneous procedures, 0.42 (range = 0-2) open procedures and 0 for osteosynthesis (p = 0.03). (Re-) operations were indicated because of (impending) fractures in 2/7 wait-and-see, 2/19 percutaneous procedure, 9/52 open procedure and 0/11 osteosynthesis patients, totaling to 31% of open re-procedures performed. Two- and 5-years revision-free survival was 75.2% and 63.5%. Median time until full weightbearing allowed for wait-and-see was 4 weeks (± SD0), percutaneous 8 (± SD6.36), open procedure 11 (± SD0.39), and osteosynthesis 14 (± SD9.17; n = 57, p = 0.51).
Conclusions: Wait-and-see for UBC resulted in a fracture during follow-up in 29% of cases. Fracture risk should be considered when discussing treatment options with patients and parents. Some UBCs required open reinterventions after percutaneous index-procedures. Open treatment and stand-alone osteosynthesis are associated with longer time until full weightbearing in UBCs, conceivably because of more frequent fractures at diagnosis.
Tumours / Miscellaneous
OP-129
Treatment outcomes of monostotic fibrous dysplasia in the proximal femur in 47 children and adolescents: Retrospective multi-center cohort study
Thom van Geloven1, Maartje Meier1, Dietmar Dammerer2, Masood Umer3, Kevin Doering4, C Soto-Montaya5, I Badr6, Philipp Scheider4, Tanja Kraus7, M Haara8, Giovanni Beltrami9, Minna Laitinen8, Domenico Campanacci10, Pieter-Bas de Witte1, Michiel van de Sande1
1Leiden University Medical Center (LUMC), Leiden, The Netherlands, 2Tirol Kliniken GmbH, Innsbruck, Austria, 3Aga Khan University Hospital, Karachi, Pakistan, 4Medical University of Vienna, Wien, Austria, 5National Cancer Institute - ESE, Bogotá, Colombia, 6Faculty of Medicine, Menoufia University, Egypt, 7Medical University of Graz, Graz, Austria, 8Helsinki University Hospital, Helsinki, Finland, 9University Hospital Meyer, Firenze, Italy, 10Careggi University Hospital, Firenze, Italy
Introduction and Objective: Fibrous dysplasia (FD) is a rare, congenital bone disease. FD-lesions can occur in one (monostotic, MFD) or multiple (polyostotic) bones, and may cause pain, fractures or deformities. For cystic FD-lesions in the proximal femur no consensus regarding optimal treatment exists. We retrospectively reviewed treatment and outcomes for cystic proximal femoral FD-lesions, including re-operations and fractures after index-procedure, revision-free survival and time until full weightbearing.
Materials and Methods: Consecutive patients with cystic MFD-lesions in the proximal femur were included from 11 centers worldwide (2000-2021). Demographics, initial treatment, complications and re-procedures during follow-up were evaluated. Index-procedures were categorized: wait-and-see, percutaneous, open procedure with cyst treatment and stand-alone osteosynthesis. Re-procedures were compared using one-way ANOVA. Time until full weightbearing was compared using Log-Rank.
Results: We included 47 patients (mean age 11.3 years (± SD = 3.29), 23 (48.9%) male). Index treatment was wait-and-see (n = 11), percutaneous (n = 7), open treatment (n = 17), or stand-alone osteosynthesis (n = 12). Mean follow-up was 6.1 years (± SD = 4.7). Mean number of open re-operations in follow-up: for wait-and-see 0.2 (range = 0-2), percutaneous treatment 1.0 (range = 0-3), open treatment 0.5 (range = 0-2) and stand-alone osteosynthesis 0.4 (range = 0-3) (p = 0.21). Median time until re-operation was 2.2 years (± SD = 3.9). Indication for re-operations was (impending) fracture in 1/11, 4/7, 7/17 and 2/12 patients respectively, comprising 61% of all open re-procedures. 1 infection occurred. Two- and 5-years revision-free survival was 78.7% and 75.1%. Median time until full weightbearing was for wait-and-see 0, percutaneous 14, open procedure 12 and stand-alone osteosynthesis 8 weeks (n = 32, p = 0.48).
Conclusions: MFD-patients with initial percutaneous treatment received more open surgeries during follow-up than patients with other index-procedures, mainly for (impending) fractures. Two-and 5-year revision-free survival remained stable around 75%. Time until full weightbearing was longer after percutaneous and open procedures compared to wait-and-see and solitary osteosynthesis. However, differences were not statistically significant and selection bias should be considered.
Tumours / Miscellaneous
OP-130
Can virtual reality headsets be used safely as a distraction method for paediatric orthopaedic patients? A feasibility study
Karen Shepherd1, Yogita Shanmugharaj2, Obada Kattan2, Michail Kokkinakis1
1Evelina London Children’s Hospital, United Kingdom, 2King’s College London, United Kingdom
Introduction and Objective: Virtual Reality (VR) has been shown to decrease pain and anxiety in clinical areas. Venepuncture, Plaster Room procedures and the Operating Theatre environment can provoke anxiety in Paediatric Orthopaedic patients. The purpose of this study was to assess the feasibility of the ‘Rescape DR.VR Junior’ headset as a distraction method within these Paediatric Orthopaedic settings.
Materials and Methods: An internal risk assessment by medical engineers was carried out to determine the safety of the VR-Headset in the three clinical areas. The device was deemed safe to be used only in the Venepuncture and Plaster Rooms, while further investigation is needed to establish its safety in the operating theatre/anaesthetic room. Thirty-three children (age range:2 -15 years) were given the option to use a VR-headset while they underwent venepuncture or a cast procedure. Anxiety scores, measured on a Likert scale, were collected pre and post-procedure. Participants were asked if they would use the device again. Subjective feedback was also collated from the supervising clinical staff.
Results: 66% (21) showed a reduction in anxiety scores, 28% (9) had no change in score; all scores being mild, 1-3 on the Likert scale. 6% (2) showed an increase in post procedure score. All participants stated they would use the device again. One patient declined the headset. Health professionals also gave positive subjective feedback and they would all use it again with their paediatric patients. No adverse events were recorded.
Conclusions: The ‘Rescape DR.VR Junior’ headset has been found to be safe and a feasible distraction method for use within the Venepuncture and Plaster Room. Further research is required to assess its use safety and effectiveness in other clinical areas including the Paediatric Orthopaedic operating theatre.
Tumours / Miscellaneous
OP-131
Asymmetric growth after percutaneous epiphysiodesis
Hannah Weinmayer1, Anne Breen2, Harald Steen2, Joachim Horn2
1University of Oslo, Norway, 2Section of Children’s Orthopaedics and Reconstructive Surgery, Oslo University Hospital, Norway
Introduction and Objective: Percutaneous epiphysiodesis (PE) is considered to be a safe method for the treatment of leg length discrepancy (LLD) and few complications are reported. However, no study has so far systematically analyzed the risk of secondary deformities which might develop due to asymmetric growth after the procedure. The aim of our study was to analyze the presence of secondary mechanical axis deviation (MAD) and change of joint orientation angles (JOA) around the knee after PE.
Materials and Methods: Patients were recruited from our institutional database of 269 patients who had undergone PE. Inclusion criteria were: PE for LLD, follow-up of at least 12 months, long standing radiographs, and no underlying pathology in the operated extremity which could cause axis deviation. Radiographs were analyzed by measuring MAD and JOA in the frontal plane before and after the procedure. Remaining growth was calculated according to the Menolaus method.
Results: 137 epiphysiodeses in 86 patients with a mean age of 13.2 (10-16.8) years could be included in the study. 51 were combined femoral and tibial and 35 were isolated epiphysiodeses in the femur (n = 18) and tibia (n = 17). Remaining growth of the physes was 1.5 (0.00 - 5.19) cm. MAD of > 7 mm was found in 15 (17%) and MAD ≥ 10 mm in 10 patients (12%). 8 cases of ≥ 10 mm MAD occurred after distal femoral epiphysiodesis (5 varus, 3 valgus) and 2 after proximal tibial epiphysiodesis (2 varus). The occurrence of deformities correlated significantly with the remaining growth at time of surgery (p = 0.006).
Conclusions: We found a significant percentage of cases with secondary frontal plane deformities after PE. There is a higher risk to develop secondary deformities after the procedure, when remaining growth in the operated physis is high. Especially those patients should be closely monitored after the procedure.
Tumours / Miscellaneous
OP-132
Use of resorbable magnesium screws in children: Systematic review of the literature and short-term follow-up from our series
Danya Falcioni1, Valentina Maestri1, Valentino Coppa1, Antonio Pompilio Gigante1
1Clinic of Adult and Paediatric Orthopedic, Azienda Ospedaliero-Universitaria, Ospedali Riuniti di Ancona, Ancona, Italy
Introduction and Objective: Biodegradable implants are of major interest in orthopaedics, especially in the skeletally immature population. Magnesium (Mg) implants are promising for selected surgical procedure in adults, but evidence is lacking. Thus, the aim of this study is to analyze the safety and efficacy of resorbable Mg screw in different orthopaedic procedures in skeletally immature patients. In addition, we present a systematic review of the current literature on the clinical use of Mg implants.
Materials and Methods: From January 2018 to January 2021, consecutive orthopaedic surgical procedures involving the use of Mg screws performed at our centre in patients < 15 years of age were retrospectively reviewed. In addition, a systematic review of the literature was performed in the main databases. We included clinical studies conducted on humans, using Mg-alloy implants for orthopaedic procedures.
Results: A total of 14 patients were included in this retrospective analysis. Mean age at surgery was 10.8 years (sd 2.4), mean follow-up was 13.8 months (sd 7.5). Healing was achieved in all the procedures, with no implant-related adverse reaction. No patients required any second surgical procedure. The systematic review evidenced 20 clinical studies, 19 of which conducted on an adult and one including paediatric patients.
Conclusions: Evidence on resorbable Mg implants is low but promising in adults and nearly absent in children. Our series included apophyseal avulsion, epiphyseal fractures, osteochondritis dissecans, displaced osteochondral fragment and tendon-to-bone fixation. Mg screws guaranteed stable fixation, without implant failure, with good clinical and radiological results and no adverse events.
Best of the Best
OP-133
Development of the LIMB-Q Kids: A new patient reported outcome measure for children with lower limb deformities
Harpreet Chhina1, Anne Klassen2, Jacek Kopec3, Anthony Cooper1
1BC Children’s Hospital, Vancouver, Canada, 2McMaster University, Hamilton, Canada, 3The University of British Columbia, Vancouver, Canada
Introduction and Objective: Our objective was to develop an internationally applicable patient-reported outcome measure (PROM) for children with lower limb deformities (LLDs)
Materials and Methods: We used a mixed method multiphase approach to develop LIMB-Q Kids. In phase 1, we conducted a systematic review to identify concepts from existing PROMs used in research with children with LLDs. These concepts formed a preliminary conceptual framework that was revised during an international qualitative study of children with LLDs. Participants (aged 8-18 years) were recruited from Canada, US, India and Ethiopia. Interviews were transcribed and coded. Analysis led to the refinement of the conceptual framework. The data were used to form a new PROM called LIMB-Q Kids. This PROM was refined through multiple rounds of cognitive debriefing interviews (CDIs) with children and input from parents and health-care professionals. The refined PROM was translated and culturally adapted into multiple languages following ISPOR guidelines, and included in a phase 2 international field-test study.
Results: The systematic review confirmed the lack of a condition specific PROM. A total of 79 qualitative interviews (39 patients, 40 parents) and 40 CDI and expert interviews were conducted between 2015 and 2020. These interviews guided the development of items and scales and further refinement in an iterative manner. The refined version of the LIMB-Q Kids consist of 11 scales (159 items) that measure appearance, physical function, symptoms (hip, knee, ankle, foot and leg), leg-related distress, and school, social and psychological function. This PROM is now being translated and culturally adapted into Arabic, Danish, Finish, German, Hindi, Swahili and Luganda. An international field-test study is now underway in 11 countries (22 sites).
Conclusions: No internationally applicable PROM exists for children with LLDs. Data from the international field-test study will be used to reduce items and perform psychometric testing of LIMB-Q Kids.
Best of the Best
OP-134
Persistently raised titanium levels in children after spinal instrumentation
Peter John Cundy1, Brian Freeman1, Georgia Antoniou1, William Cundy1
1Orthopaedic Surgery, Women’s & Children’s Hospital, North Adelaide, Australia
Introduction and Objective: Metal ion levels after paediatric spine surgery have shown an immediate initial peak of serum metal levels and persistence beyond 1 year. Concerns have been raised regarding long term effects.
Materials and Methods: We investigated 5 spinal instrumentation systems, namely Universal Spine System (USS) (Synthes), Expedium (DePuy Synthes), Verse (Expedium DePuy Synthes), K2M-Mesa and Response (Ortho-pediatrics). 11 patients in each group apart from K2M with 12 patients giving a total of 56 patients. This prospective study enrolled children undergoing elective spinal surgery for deformity with sampling of blood at induction of general anesthesia, as well as at immediately post-op, days 1, 7, 30, 6 months, 1-year and 2-years. Patients acted as their own controls with pre-operative sampling. Testing utilized high-resolution inductively coupled plasma mass spectrometry.
Results: Titanium levels showed a rapid increase by 7 days and a peak at 30 days that was maintained at the 2-year assay despite minor declines in levels at 6 months and 1-year. Titanium levels showed a mean increase of 5.1 times baseline levels at 2 years. Chromium levels were noted to peak in the immediate post-op sample, consistent with earlier studies supporting release of chromium from electrosurgery handpieces. Cobalt levels were highest in patients receiving Cobalt-Chromium rods with maximum levels at 30 days Cobalt, Chromium and Nickel levels closely approximated baseline levels at 2 years, whilst titanium continued to rise
Conclusions: Titanium is known to accumulate in solid organs especially the liver, spleen, heart and lymph nodes. Titanium is also known to cross the placental barrier and enter the circulation of the foetus in rodents and humans that exposes the offspring of mothers with spinal implants to titanium. The effects remain unclear but do warrant assessment for birth defects or developmental issues in the children of mothers with spinal implants.
Best of the Best
OP-135
The effect of knee height asymmetry on gait biomechanics
Haluk Altiok1, Jeremy Bauer2, Jacqueline C. Simon1, Abdal Kawaiah1, Robert Burnham3, Cathleen Buckon2, Susan Sienko2, Ann Flanagan1, Karen Kruger1, Joseph Krzak1
1Shriners Hospitals for Children - Chicago, Chicago, USA, 2Shriners Hospitals for Children, Portland, USA, 3Loyola University Medical Center, Maywood, USA
Introduction and Objective: Though the primary goal for limb length discrepancy (LLD) management is to equalize the leg lengths, symmetry between corresponding long bones is usually not achieved, leading to knee height asymmetry (KHA). To date, there is minimal information on what effect KHA has on gait biomechanics and joint loading. Thus, the purpose of this study is to determine the impact of KHA on gait biomechanics.
Materials and Methods: 17 subjects with KHA following limb equalizing surgery and 10 healthy controls were enrolled. Subjects participated in gait analysis. Gait data were collected using self-selected walking. Three trials for each limbs were obtained. Lower extremity kinematics, kinetics, work generated/absorbed and total work were calculated. Standing lower limb x-rays and scanograms were used to measure LLD and calculate tibia-to-femur (TF) ratio. Two sample t-tests were used to compare difference in standing LLD, TF ratio, KHA, work and work symmetry between groups. Bivariate correlation using Pearson correlation coefficients were conducted between TF ratio and total mechanical work, as well between knee height asymmetry and total work asymmetry (α = 0.05).
Results: There were no differences between LLD however there were differences between TF ratio and knee height asymmetry. Results demonstrated a non-significant relationship between TF ratio and mechanical work among individual legs. However, a significant positive correlation between knee height asymmetry and both work generated asymmetry (r = 0.62, p < 0.001) and total work asymmetry (r = 0.54, p = 0.003) was identified. In other words, greater knee height asymmetry (difference in TF ratio) between limbs resulted in more asymmetrical mechanical work during walking.
Conclusions: These findings may have implications for management of LLD. Alterations in joint loading and asymmetrical total mechanical work during gait could lead to increased incidence of osteoarthritis. Surgeons may want to consider prioritizing achieving knee height symmetry as a postoperative goal when correcting limb length discrepancy.
Best of the Best
OP-136
Patient-reported outcomes of over 900 adults who had childhood Legg-Calve-Perthes disease (LCPD)
Harry K.W. Kim1 2, Molly McGuire1, Roi Armakias3, Michael MIllis4, Bella Vakulenko-Lagun3
1Scottish Rite for Children, Dallas, USA, 2UT Southwestern Medical Center, Dallas, USA, 3University of Haifa, Haifa, Israel, 4Boston Children’s Hospital, Boston, USA
Introduction and Objective: There is very little data on how LCPD patients are functioning as adults. Of studies that are available, most are retrospective studies with < 60 patients and no comparison of outcome to age and gender matched normative data. The purpose of this study was to collect patient reported outcome data of adults who had childhood LCPD using a web-based survey and to compare their results to normative data.
Materials and Methods:REDCap-based web survey was built and advertised among Perthes support groups. The survey included childhood and adult Perthes history, SF-36, and Hip Disability and Osteoarthritis Outcome Score (HOOS). HOOS is a validated hip disability measure for pain, other symptoms, daily living, sport/recreation, and quality of life. SF-36 is a validated health measure for physical, social, general, and mental health.
Results: Of 1182 respondents who completed the survey, 921 (M 408: F 513) did not have a total hip replacement and are the focus of this study. Most respondents were from USA (433), UK (245), Australia (93), and Canada (35). The mean age at survey was 38 ± 12 years (range 18-75). In comparison to the normative data, the LCPD respondents had significantly lower HOOS scores in all 5 scales (p < 0.0001) for all age groups. Similarly, SF-36 scores of the respondents were significantly lower (p < 0.0001) for all scales except for 55+ age group. Females, higher BMI, and age > 11 at onset had significantly worse SF-36 and HOOS scores with female sex being the strongest negative factor.
Conclusions: Adult LCPD respondents of the survey, especially females, had significantly worse pain, physical function, mental health, and hip related quality of life than age matched general population. This web-based survey provides a large dataset which confirms the burden of LCPD in adults who had childhood LCPD.
Best of the Best
OP-137
Operative treatment of distal tibial epiphyseal fractures with bioabsorbable screws - nine years of experience
Marcell Varga1, Tamás Kassai1, Gergő Józsa2
1Péterfy Sándor Utcai Hospital-Clinic and Trauma Centre, Budapest, Hungary, 2Gyermekgyógyászati Klinika, Pécs, Hungary
Introduction and Objective: Distal tibial epiphyseal fractures with a displacement greater than 2 mm usually require reduction and surgical treatment. The aim of the surgery are to restore joint congruence and prevent growth disorder. The gold standard operative method is open or closed reduction and screw osteosynthesis. Screws made of bioresorbable material can make a second surgery unnecessary.
Materials and Methods: Between 2011 and 2020, a total of 51 children underwent surgery with an absorbable implant, (BRI group, Bioeretec®, ActivaScrew™) while 79 children underwent surgery with a metal alloy screw (MI group). The distribution of injuries based on the Salter -Harris (SH) classification was as follows: 15 SHII,15 SHIII, 21 SHIV injuries in the BRI group, 36 SHII, 18 SHIII, 25 SHIV injuries in the MI group. The mean follow-up time was 2.7 years in the BRI group (1-9 years) and 1.2 years in the MI group (1-6 years).
Results: We found no difference in the incidence of minor (n = 2 in the BRI group, n = 3 in the MI group) or major complications (n = 1 in the BRI group, n = 2 in the MI group).One case required second surgery in the BRI group, whereas in the MI group, screws were removed in all cases. Growth disturbance was observed in 2 children, both in the MI group. No septic complication or tendon injury was observed in either group. In 8 children, a late MRI examination confirmed the absorption of the implants.
Conclusions: Absorbable screws are good alternatives in paediatric distal tibial epiphyseal fractures. Based on our retrospective comparative studies, the number of complications does not increase compared to conventional techniques. Avoiding a second intervention results financial savings and reduction of the surgical risk.
Best of the Best
OP-138
Short bioresorbable intramedullary nailing of severely displaced distal forearm fractures in children - an alternative to K-wires
Marcell Varga1, Gergő Józsa2, Zsófia Krupa1, Tamás Kassai1
1Péterfy Sándor Utcai Hospital-Clinic and Trauma Centre, Pediatric Trauma, Budapest, Hungary, 2Gyermekgyógyászati Klinika, Pécs, Hungary
Introduction and Objective: Treatment of severely displaced and shortened fractures usually require closed reduction. Most authors recommend osteosynthesis if the fracture remains unstable. The gold standard operative method is percutaneous pinning with Kirschner-wires. K-wire related complications like migration of the pins, superficial infections, skin irritation are relatively frequent. We present the results of a retrospective and a prospective multicenter study between the K-wire technique and our new bioresorbable intramedullary nailing procedure.
Materials and Methods: K-wire osteosynthesis and bioresorbable nailing (ActivaPin™ and Activa IM-Nail™) has been made in four pediatric trauma center. We compared the incidence of minor and major complications (superficial skin infection, tendon injury, nerve injury, secondary displacement, deep infection, skin irritation). The study periods were between July 2018 and January 2020, and between January 2021 and April 2021. The follow-up lasted from half to 2 years. Inclusion criteria was the clinical diagnosis of distal radial/forearm metaphyseal fractures with complete displacement, the presence of open growth plates and the child’s age under 14 years. A total of 74 children were studied in the retrospective group (33 treated with ActivaPin™ 41 treated with K-wires) and 45 children in the prospective group (25 treated with Activa IM-Nail™ and 20 treated with K-wires).
Results: No significant differences in age or right or left hand involvement were observed in either group. (p > 0.05) Minor complications were significantly less in the bioabsorbable groups, major complications occurred more but not significantly in the K-wire groups. No second intervention (implant removal) was required in thebioresorbable groups.
Conclusions: Short intramedullary bioresorbable nailing may be a good alternative technique in the treatment of severely displaced distal metaphyseal forearm fractures in children. It is a stable, physis sparing procedure without the need of implant removal,
E-Posters
EP-01
Prolonged bisphosphonate therapy in children with severe osteogenesis imperfecta could create intramedullary canal obliteration or sclerosis
Darko Anticevic1, Željko Jeleč1
1Department of Orthopaedic Surgery, St. Catherine Hospital, Zagreb, Croatia
Introduction and Objective: Bisphosphonates (BPs) are only cure for patients with osteogenesis imperfecta (OI) in regions of the world where surgery is not available. Prolonged BPs therapy in case of significant deformity of the long bone will confront a surgeon with an unexpected problem - sclerosis/obliteration of intramedullary (IM) canal. We look closer on this problem.
Materials and Methods: Inclusion criteria - patients with severe deformity of the long bone segment i.e. 60 or more degrees of deformity in one plane, prolonged treatment with BPs, and no previous surgery. Medical records were reviewed for number of BPs infusions before the surgery, as well as preoperative radiographs with IM sclerosis/obliteration of the tibia or femur. IM sclerosis was measured on lateral radiographs because severe deformed segments had a specific “rib shape”. Both ends points of sclerotic area were determined, and a whole surface of sclerotic area as well as percentage of sclerotic part was calculated. Measurements were three times and final result was arithmetic value. Varus and procurvatum angles were measured. Our control group were surgically treated OI patients without IM sclerosis but matched to age and severity of disease.
Results: We identified 17 segments (14 femurs and 3 tibias) in 9 patients which had IM sclerosis or obliteration, frequently on the deformity apex. Obstacles during surgery were splitting of bone during drilling; drill breakage; “false route”; prolonged surgical time and increased blood losses. Suggestion how to avoid surgical obstacles are: precise preoperative planning; careful surgical technique due to poor bone quality; gradual, slow IM reaming; exchange of usage of surgical drill and manufacturer designed drill; sufficient orthogonal radiographic intra-operative controls; excision of triangular sclerotic bone block.
Conclusions: Results suggest that more than 15 cycles of BPs infusions will increase chance for IM sclerosis and one should correct long bone deformity earlier.
EP-02
Progress and recurrence of the disease in dysplasia epiphesealis hemimelica: A systematic review of literature
Alina Khodorovskaya1, Vladimir Kenis1, Eugeniy Melchenko1
1H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery, Russian Federation
Introduction and Objective: Dysplasia epiphysealis hemimelica (DEH) is characterized by cartilage overgrowth in the epiphyses and their equivalents. The number of cases presented in the literature is limited, and systematic review of follow-ups should be helpful for the better understanding of natural history of the disease.
Materials and Methods: A systematic literature review from 1950 to June-2021 was performed. We searched MEDLINE, Scielo, Google scholar, EBSCO, E-library for full-text articles. Inclusion criteria were: surgically treated pediatric DEH cases of lower extremities, not associated with other bone pathology, follow- up period > 2 years The described cases were divided into 3 groups according Azouz’s classification (1985).
Results: We found a total of 129 studies (355 patients), 114 studies (258 patients) were included. Localized DEH were manifested in any age (till epiphysis or their equivalents maturation); classical - before the age 14 y.o (> 80% - before 8 y.o.); generalized - before 5 y.o. New revealed X-ray-confirmed overgrowth of the epiphyses or their equivalents was diagnosed during the first two years of follow-up. New revealed overgrowth was significantly more common in children < 5 years (p = 0.004) to compare with the elder age group. X-ray-confirmed recurrence of the cartilage overgrowth after surgery was most common during the first year after surgery irrespective to the age. The recurrence rate was approximately equal for classical and localized groups (p = 0.07); recurrence in the generalized group was significantly higher than in other groups (p = 0.026).
Conclusions: Children > 5 years old do not require radiography for follow-up more than 2 years for screening for the additionally involved epiphyses and possible recurrence of the cartilage overgrowth after surgery. Patients < 5 years old and\or children with generalized DEH demonstrate highest risk of the further overgrowth and need frequent radiological screening. MRI is possibly more efficient screening tool for these patients.
EP-03
Allografting is an effective biological method of fixation and increases bone trophicity in osteogenesis imperfecta
Sarah El Yahiaouni1, Marine De Tienda1, Georges Finidori1, Valérie Dumaine1, Alina Badina1, Stéphanie Pannier1, Mathilde Gaume1, Zagorka Péjin1
1Necker Hospital, Paris, France
Introduction and Objective: Osteogenesis imperfecta (OI) in children is responsible for deformities and fractures with an inherent risk of developing non-union. Indications and efficiency of allografting are poorly documented in this specific population. The objective of this retrospective study was to evaluate the efficacy of this technique in the treatment of OI patients.
Materials and Methods: 36 consecutive lower limb allograft procedures (26 femurs and 10 tibias) were performed at our institution between 2011 and 2021 in 22 patients (mean age, 13.3 years). They were listed according to Sillence classification into type III (17) and type IV (5). The indications for the surgery were as follow: fracture (12), correction of deformity (20) or treatment of non-union (4). In all cases, allografting was added to compensate areas of fragility and in 28 cases they were used as a means of fixation to provide structural support and to avoid the need for plate fixation. The duration of bone consolidation and allograft fusion were assessed at regular intervals (first postoperative visit at 6 weeks, 3, 6, 9 and 12 months). Mechanical and infectious complications as well as Gillette functional score were reported.
Results: The mean follow-up was 6.7 years (range, 1 to 10 years). On average, bone consolidation was achieved after 3.3 months and graft fusion in 7.7 months. No allograft-related complications were observed and particularly no secondary displacement after biological fixation. The Gillette functional score was globally improved and remained stable in 3 cases.
Conclusions: In this series, allografting in children with OI appeared to be a reliable method of biological fixation, allowed a fast fusion and contributed to increase bone trophicity.
EP-04
Role of fibular shortness in genu valgum deformity in multiple hereditary exostosis patients
1Timone Enfants, Pediatric orthopedics, Marseille, France
Introduction and Objective: Genu valgum is a frequent complication in Hereditary Multiple Exostoses (HME) patients. Differential growth between fibula and tibia is suspected in the onset of leg deformity. Our objective was to evaluate the role of relative fibular length in genu valgum occurrence in HME patients.
Materials and Methods: Between 2009 and 2020, we retrospectively reviewed the radiographs of 19 patients (38 lower limbs) between 6 years old and skeletal maturity. Different parameters were measured, including Hip-Knee-Ankle axis (HKA), fibular and tibial lengths, fibula/tibia ratio (F/T), physeal gaps (prox-Gap and dist-Gap) and mechanical axis of the lower limbs (mLDFA, mMPTA and mLDFA). Based on the first radiograph, patients were stratified according to their HKA (Valgus vs Normal).
Results: Mean age at first radiograph was 10 years old. F/T ratio and dist-Gap were significantly lower in Genu Valgus (87 vs 93%, p < 0.01 and 0 vs 2%, p = 0.02, respectively). Prox-Gap was significantly higher in Valgus group (11 vs 8%, p < 0.01). HKA was significantly correlated to mLDFA, mMPTA, mLDTA, F/T ratio, but not to proximal nor distal Gap.
Conclusions: These results reinforce the hypothesis that fibular relative shortness contributes to genu valgum in MHE patients, by modifying anatomical relationship between tibia and fibula at their proximal and distal ends. Fibular shortness results in a lateral epiphysiodesis effect on the tibia leading to progressive valgus deformity. Understanding mechanisms underlying genu valgum in MHE patients is of major importance in order to be able to propose adequate treatment.
EP-05
An evidence-based clinical practice guideline for developmental dysplasia of the hip under the age of 1 year. Part 1: Centered hips
Christiaan van Bergen1, Pieter-Bas de Witte2, Willeboordse Floor3, de Geest Babette L.3, Foreman - van Drongelen Margret4, Burger Bart J.5, Yvon Den Hartog6, JH van Linge7, Pereboom Renske M.8, Robben Simon9, Adhiambo Witlox9, Witbreuk Melinda M.E.H.10
1Amphia, The Netherlands, 2LUMC, 3Knowledge Institute of Medical Specialists, 4Diagnostiek voor U, 5North West Hospital Group, 6Medisch Spectrum Twente, 7Reinig Haga Orthopedic Center, 8Dutch Hip Patient Association, 9Maastricht University Medical Center, 10OLVG, AUMC
Introduction and Objective: Despite the high incidence of developmental dysplasia of the hip (DDH), treatment is very diverse. Therefore, the Dutch Orthopedic Society developed a clinical practice guideline with recommendations for optimal and uniform treatment of DDH. This abstract summarizes the guideline on centered DDH (i.e., Graf types 2A-C).
Materials and Methods: The guideline development followed the criteria of AGREE II (Appraisal of Guidelines for Research and Evaluation II). A systematic literature review was performed to identify randomized controlled trials and comparative cohort studies including children < 1 year with centered DDH. Articles were included that compared 1) treatment with observation, 2) different abduction devices, 3) follow-up frequencies, and 4) discontinuation methods. Recommendations were based on Grading Recommendations Assessment, Development and Evaluation (GRADE), which included the literature, clinical experience and consensus, patient and parent comfort and costs.
Results: The systematic literature search resulted in 430 potentially relevant articles, of which five were included. Final guideline recommendations are: 1) Initially observe 3-month-old patients with centered DDH; start abduction treatment if the hip does not normalize after 6-12 weeks (GRADE moderate); 2) Prescribe a Pavlik harness to children < 6 months with persisting DDH on repeated ultrasonography; consider alternative abduction devices for children > 6 months (GRADE not applicable); 3) Assess patients every 6 weeks (GRADE not applicable); and 4) Discontinue the abduction device when the hip has normalized or when the child is 12 months (GRADE very low).
Conclusions: This abstract presents a summary of part 1 of the first evidence-based guideline for treatment of centered DDH in children < 1 year. Part 2 presents the guideline on decentered DDH in a separate abstract.
EP-06
Gestational week and sonographic acetabular roof a-angle. A prospective, pilot, cohort of Caucasian - Greek population
12nd Orthopaedic Department, “Papageorgiou” General Hospital of Thessaloniki, Thessaloniki, Greece, 22nd Neonatal Department and Neonatal Intensive Care Unit,”Papageorgiou” General Hospital of Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece
Introduction and Objective: We aimed to investigate if there are differences in the bony acetabular roof a-angle according to gestational age of birth.
Materials and Methods: The hips of neonates born in a single tertiary hospital were scanned according to Graf’s method. The examination was done by two trained orthopaedic surgeons, within the first week of life, and hip a and b angles were measured. The neonates’ weight, gestational age, parity, presentation, gender, ethnicity, family history of ddh and results from clinical examination were recorded. The study was prematurely terminated due the COVID-19 pandemic outbreak.
Results: Between April 2020 - October 2020, 354 consecutive neonates (187 male-164 female) were scanned. 89.3% were Caucasian-Greek/Balkan and the rest were Asian/Roma and African. 17 were born at < 36 weeks, 25 at 36-37 weeks, 33 at 37-38, 99 at 38-39, 89 at 39-40 and 91 at > 41 weeks. Overall there was 74.5% Graf Type I and 25.5% Type II right hips and 80.2% and 19.8% for the left side respectively. Mean a-angle for neonates < 37 weeks was 61.7 (SD 7.1) and 64 (SD 7) for right and left hip respectively, and 62.4 (SD 5.9) and 63 (SD 5.8) for > 37 weeks, with no significant difference between groups. Subgroup analysis did not reveal any difference in the a-angle between neonates born at < 36 weeks, 37, 38, 39 or > 40 weeks. There was significant difference in the a-angle of the left hip between males and females (p = 0.043). No correlation was evident between neonatal birth weight and a-angle.
Conclusions: No major differences in acetabular roof a-angle was evident in babies born at 36 weeks to term.
EP-07
Appropriate surgical timing of Salter innominate osteotomy for acetabular dysplasia in children
1Orthopaedic Surgery, Aichi Children’s Health and Medical Center, Obu, Japan, 2Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan, 3Comprehensive Pediatric Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
Introduction and Objective: Salter innominate osteotomy (SIO) provides favorable results for treating acetabular dysplasia of young children. In this study, we examined the mid-term results of SIO by age at surgery to clarify the upper age limit for this procedure.
Materials and Methods: We retrospectively examined 50 hips of 42 patients (8 boys, 34 girls) with acetabular dysplasia who underwent SIO and were followed-up until skeletal maturity. Center-edge angle (CEA) were measured based on anteroposterior radiographs of the hip taken before SIO, five weeks after SIO, and at the latest follow-up. Severin classification was evaluated at the latest follow-up. Patients were categorized into three groups according to the age at surgery: less than 7 years of age (group A), 7 to 8 years of age (group B), and 9 years of age or older (group C).
Results: The mean preoperative CEA of 0.9° (-9~8°) improved to 17.1° (6~24°) postoperatively, and remodelled to 28.1° (13~40°) at the latest examination. Overall, 45 hips (90%) were classified as the Severin I or II, with 93% in Group A, 100% in Group B, and 57% in Group C. In Group C, postoperative acetabular coverage was similar to other Groups (16.6° in A, 15.9° in B, and 18.1° in C), although the final outcome was not satisfactory. The average improvement in the CEA from postoperative to skeletal maturity was significantly smaller in Group C than in other Groups (13.5° in A, 11.6° in B, and 5.0° in C).
Conclusions: SIO does not necessarily produce satisfactory results in patients with acetabular dysplasia aged 9 years or more because postoperative remodelling capability can hardly be expected. Our recommendation is to perform SIO on patients under 8 years of age.
EP-08
What is the interobserver reliability of an ultrasound enhanced physical examination of the hip in infants? A prospective study on the ease of acquisition of skills to diagnose hip dysplasia
Neha Jejurikar1, Leon Moscona Mishy1, Monica Rubio1, Romina Cavallaro1, Pablo Castaneda1
1Orthopaedic Surgery, New York University Grossman School of Medicine, New York, USA
Introduction and Objective: The consequences of DDH can be mitigated with early diagnosis and nonoperative treatment, but existing approaches to early diagnosis do not address the current training deficit in making an early diagnosis. The objective of this study was to determine if ultrasound can be taught and used reliably by different providers to identify neonates with DDH.
Materials and Methods: This was a prospective observational study of a series of neonates referred for evaluation of their hips. An experienced clinician trained three second examiners in performing an ultrasound-enhanced physical examination. A total of 227 infants (454 hips) were examined by one of the three second examiners and the experienced clinician (gold standard) to assess reliability. Of the 454 hips reviewed, there were 18 dislocations, 24 unstable hips, 63 dysplastic hips, and the rest were normal. The cohort was composed of a series of patients younger than 6 months referred to a speciality pediatric orthopaedic practice
Results: Ultrasound enhanced physical exam of the hip was easily taught and the results were reliable amongst different levels of provider. The intraclass correlation coefficient between the gold-standard examiner and the other examiners for all hips was 0.915 (p = 0.001). When adjusting for only the binary outcome of normal versus abnormal hips, the intraclass correlation coefficient was 0.97 (p = 0.001). Thus, the agreement between learners and the experienced examiner was very high after learners completed the course.
Conclusions: After a 2-hour course, physicians were able to understand and reliably examine neonates using ultrasound to assess for DDH. The success of the didactic approach outlined in this study supports the need for ultrasound enhanced exam training for the diagnosis of DDH. This finding highlights the need for further research in implementing ultrasound-enhanced physical examinations on a broader scale.
EP-09
Development and validation of a diagnostic aid for DDH in early infancy: building on the results of a multinational EPOS study
1Great Ormond Street Hospital for Children, United Kingdom, 2Nuffield Orthopaedic Centre, United Kingdom, 3Royal London Hospital, United Kingdom, 4Royal National Orthopaedic Hospital, London, United Kingdom
Introduction and Objective: We previously developed standardised diagnostic criteria for DDH in early infancy in a multinational EPOS study. The criteria were validated in a sample including members of POSNA. Such criteria would enable non-experts to evaluate infants for DDH in a manner approaching the practice of orthopaedic surgeons, with the potential to improve early diagnosis. We present the development and validation of a diagnostic aid for DDH.
Materials and Methods: We devised a diagnostic aid for use in primary care based on our previously validated diagnostic criteria; this was done in several steps with feedback of target diagnosticians. We performed a diagnostic test study in an enriched sample of target infants. The index test was the diagnostic aid administered by 38 family physicians, who evaluated 354 6-to-8-weeks-olds for DDH. The reference standard test was the outcome of the infant’s examination in a specialist infant hip clinic. The tests were performed concurrently in a setting mimicking primary care. Blinding was maintained at all levels.
Results: The diagnostic aid resulted in a 9-item binary checklist accompanied by a short video. The prevalence was 23.7% (95% CI 19.4%, 28.5%); PPV = 58.9% (48.9%, 68.3%); NPV = 91.5% (87.3%, 94.7%), post-test disease likelihood despite negative test = 8.5% (5.3%, 12.7%), sensitivity = 75% (64.4%, 83.8%); specificity = 83.7% (78.7%, 87.9%). Wrongly detected were leg length discrepancies (n = 19), Ortolani (n = 9), Barlow (n = 10) and limited abduction (n = 7). Excluding mild ultrasonic abnormalities from analysis gave a sensitivity of 91.1% and specificity of 83.7%.
Conclusions: The diagnostic aid was easy-to-use in routine clinical care. It demonstrated face, content and criterion validity in hands of family physicians. It has potential to enable family physician or paediatricians to evaluate infants for DDH in a manner approaching the practice of orthopaedic surgeons. It will be further evaluated in a randomised controlled trial for its effectives.
EP-10
Does age at start of treatment have an influence of follow-up development of unstable hips?
Bettina Westhoff1, Hannes Kubo1, Hakan Pilge2, Jan-Philipp Holthoff1, Martin Hufeland1, Ruediger Krauspe1
1Heinrich Heine University Düsseldorf, 2Orthopädicum München PD Dr. med. H. Pilge, München, Germany
Introduction and Objective: It is well known that the age at start of therapy in unstable hips has an influence on treatment success. The objective of this study was whether after successful treatment of unstable hips the age at onset of therapy still has an influence on the further development of the hips.
Materials and Methods: From 11/2001 to 04/2015 the radiographic development of 93 unstable hips (type D, 3, 4 according to Graf) of 75 patients was examined. Inclusion criteria were 1) history of successful treatment of unstable hips with Fettweis plaster and 2) availability of a pelvic X-ray at the age of 12-24 and 24-48 months. X-rays were analyzed for the AC-index. The result was graded according to the Tönnis-classification as “normal” (< 1s), “slightly dysplastic” (1s-2s) or “severely dysplastic” (> 2s). Children with secondary hip dysplasia were excluded.
Results: At the age of 13.9 months 38.7% showed a normal, 36.6% a slightly dysplastic and 24.7% a severely dysplastic hip; at the age of 28.5 months the rate of severely dysplastic hips increased to 33.0%. Statistical analysis revealed the age of 8 weeks at start of treatment as turning point concerning the further development: while in group 1 (< 8 weeks, n = 16) no hip deteriorated and the rate of normal hips increased (37.5% to 50.0%) in group 2 (> 8 weeks, n = 77) 26% hips deteriorated, the rate of severely dysplastic hips increased from 24.7% to 35.1%. The initial hip type didn’t have an influence.
Conclusions: Radiological controls after treatment of unstable hips with Fettweis plaster show poorer outcome after delayed start of treatment (> 8 weeks). The development seems to be independent of the initial ultrasound hip type. Regular X-ray controls of all hip types seem to be justified to detect residual dysplasia.
EP-11
AVN: How to minimize it? The effectiveness of Morel progressive traction in DDH (III-IV grade IHDI)
Federica De Rosa1, Daniele Sini1, Chiara Arrigoni1, Carlo Origo1
1AON SS. Antonio Biagio e Cesare Arrigo, SC Ortopedia Pediatrica, Alessandria, Italy
Introduction and Objective: The aim of the current study is to evaluate radiographic outcomes such as development of correct coxo-femoral geometry, percentage of reluxation and rate of osteonecrosis in CHD (congenital hip dislocations), treated by Morel progressive traction preliminary to close reduction during the last 20 years at our Institute.
Materials and Methods: We reviewed clinical and instrumental data of 61 patients (73 hips) affected by CHD, with a follow-up of at least 5 years. Recurrence rate of the dislocation, degree of avascular necrosis of the femoral head (Kalamchi & MacEwan), acetabular index (AI), CE angle of Wiberg (CEA) and Severin score were calculated.
Results: 94.5% (69) of the 73 hips required closed reduction (CR), 4 hips were treated by open reduction (OR); reduction remained stable in 69 hips out of 73 (94.5%), reluxation rate was 5.5% (4 hips, 2 previously CR e 2 OR). Mean AI after 1 year of treatment is 19.5°. Osteonecrosis rate is 6.8% (5 hips), of which 60% (3 hips) had been treated by OR. Most of the hips did not develop permanent disabilities (Severin I - II 96%) and only 8.2% (6 hips) underwent subsequent surgery for residual dysplasia. There were neither short nor long term traction-related complications.
Conclusions: Morel traction is a safe procedure, it drastically reduce the need for OR of the CHD, since it allows the noble structures to progressively adapt to the new coxo-femoral configuration. Although it is impossible to avoid the risk of osteonecrosis, it reduces it to the lower percentages reported in literature. The hospitalization costs are worth the benefit of a CR, which reduces the risk of surgically violating the vascularity of the neonatal femoral head, indirectly prevents subsequent bony surgery and may avoid the future need for a early total hip arthroplasty.
EP-12
Comparison of pubo femoral distances in lateral versus supine positioning of the child
Hans-Christen Husum1, Christian Klitt Jensen1, Michel Bach-Hellfritzsch2, Mads Henriksen2, Ole Rahbek1
1Aalborg University Hospital, Interdisciplinary Orthopaedics, Aalborg, Denmark, 2Aarhus University Hospital, Department of Radiology, Aarhus, Denmark
Introduction and Objective: Ultrasound screening for developmental dysplasia of the hip (DDH) is conventionally based upon the method developed by Graf. In 2013 the pubo femoral distance (PFD) was proposed as a new ultrasound screening measurement, defined as the minimally measurable distance between the medial aspect of the femoral head and the pubic bone, but no consensus exists on the positioning of the child when performing the examination. Our aim is to examine the agreement of PFD when measured with the child in the lateral versus supine position.
Materials and Methods: We included a consecutive series of children referred for hip ultrasound suspect for DDH during a period of two months. The PFD measurement was obtained for each child for both hips, afterwards the child was placed in the supine position and the PFD measurement was repeated on both sides. Ultrasound examinations were performed by two experienced pediatric musculoskeletal radiologists. Mean PFD values for lateral and supine positioning were compared using Student’s paired t-test and controlled for age of the child using linear regression. Agreement was analyzed using Bland Altman plot.
Results: We included 30 children (15 boys), mean age at examination was 34 days (range 13-83). Mean PFD in lateral position was 3.5 mm 95%CI (3.2; 3.7) and did not differ significantly from mean PFD in supine position at 3.6 95%CI (3.4; 3.9). Mean difference in PFD between examination positions was 0.16 mm 95%CI (-0.31; 0.58) and was not significantly correlated to the child’s age at examination (p = 0.062). Inspection of the Bland Altman plot did not reveal a systematic difference in PFD between examination positions.
Conclusions: Shifting from lateral to supine examination position of the child had no impact on PFD measurements. These findings underline the versatility of the PFD measurement as a screening tool for DDH.
EP-13
Residual dysplasia in left-sided and right-sided hip dislocation in children with developmental dysplasia of the hip
Hsin-Ying Lin1, Suzanne de Vos-Jakobs2, Stijn Westerbos2, Max Reijman1
1Orthopedics and Sports Medicine, Erasmus MC, Rotterdam, The Netherlands, 2Pediatric Orthopedics, Erasmus MC Sophia Kinderziekenhuis, Rotterdam, The Netherlands
Introduction and Objective: Developmental dysplasia of the hip (DDH) is the most common musculoskeletal abnormality in infants and young children. Despite the fact that the left hip is most frequently affected, our clinical experience suggests a poorer outcome for right-sided DDH. Based on this hypothesis, we studied the outcomes of right-sided DDH in comparison to left-sided DDH up to 8-years follow-up.
Materials and Methods: We identified all children with unilateral hip dislocation at Erasmus MC - Sophia Children’s Hospital from 2002-2012, diagnosed with DDH before the age of 1 year and with minimum follow-up of 8 years. The outcome measures were residual dysplasia (based on acetabular index) at the age of 1, 2, 5 and 8 years old, surgical reduction rates, additional surgery and complication rates.
Results: Out of a consecutive series of 555 patients 298 could be included (17 males; median age at diagnosis 4.0 [IQR 3.0-5.5] months): 191 patients (64.1%) had left-sided hip dislocation and 107 (35.9%) had right-sided hip dislocation. There was no significant difference in residual dysplasia between the two groups at 1-, 2-, 5- and 8-year follow-up, respectively 34.0% vs. 24.2% (p = 0.107), 74.1% vs. 70.1% (p = 0.565), 74.1% vs. 66.2% (p = 0.261) and 65.3% vs. 53.8% (p = 0.199). There was no significant difference in surgical interventions between the left-sided and right-sided hip dislocation groups: additional surgical reduction (14.7% vs. 15.0%, p = 0.945) and additional surgery for residual dysplasia (8.9% vs. 10.3%, p = 0.695). There was no significant difference in complication rate between the groups: avascular necrosis (19.4% vs. 15.9%, p = 0.454) and re-dislocation (11.5% vs. 9.3%, p = 0.561).
Conclusions: In children suffering from DDH, right-sided hip dislocation does not have poorer outcomes compared to left-sided hip dislocation at 8-year follow-up.
EP-14
Parental experiences of children with developmental dysplasia of the hip: A qualitative study
Wesley Theunissen1, Marieke van der Steen1, Florens van Douveren1, Adhiambo Witlox2, Jaap Tolk3
1Máxima MC, Veldhoven, The Netherlands, 2Maastricht UMC+, Maastricht, The Netherlands, 3Erasmus MC, Rotterdam, The Netherlands
Introduction and Objective: Parental involvement and compliance to treatment are essential to provide optimal care for children with Developmental Dysplasia of the Hip (DDH). Despite the crucial role of parents in DDH care, a knowledge gap exists regarding the experience of parents caring for a child with DDH. The aim of this qualitative study is to explore the experiences of Dutch parents of children with DDH during the diagnostic and treatment process in the first year of life.
Materials and Methods: A qualitative study by means of individual semi-structured interviews on parental experience during treatment was conducted by a trained researcher. Parents of children aged younger than 1 year, who were treated for DDH with a Pavlik harness participated until data saturation was achieved. Population diversity was ensured by purposive sampling. Interviews were digitally audio recorded, transcribed verbatim and independently reviewed and coded by two researchers. Final categories and themes were discussed in the study group.
Results: Twenty parents were individually interviewed (95% female, mean age 31 and mean interview duration 31 minutes). Three main themes were identified: (1) insecurity, (2) interference with daily life and (3) Covid-19. Insecurity was underlined by: insufficient information, unclear overview of patient journey, discrepancy in expectation and reality, overwhelmingness by diagnosis, long-term consequences and acceptance/effect of treatment. Essential constituents of interference with daily life were: mother-child relationship, reaction surrounding, work parents, sleepless nights and psychological burden. Covid-19 led to a delay in diagnosis and prohibited presence of both parents in the hospital.
Conclusions: This study offers novel insights into parental experiences in DDH care. Most prominent reported was the feeling of insecurity due to insufficient information and a lack of overview of the patient journey. Future research and interventions should focus on optimizing information provision for parents of children with DDH.
EP-15
Traction assisted reduction compared with surgical reduction for treatment of walking age developmental dysplasia of the hip
Jason Chinnappa1 2, Anne-Laure Simon1, Alexandre Gounot1, Philippe Souchet1, Brice Ilharreborde1
1Department of Orthopaedic Surgery, Hôpital Universitaire Robert Debré, Paris, France, 2Department of Orthopaedic Surgery, Sydney Children’s Hospital, Sydney, Australia
Introduction and Objective: Treatment of dislocations in children with developmental dysplasia of the hip (DDH) discovered at the commencement of walking can be challenging. This study aims to describe and compare the results of traction reduction (TR) with surgical reduction (SR) in children with DDH diagnosed at walking age.
Materials and Methods: Hospital coding records were used to identify all DDH patients aged 9 months or older between 2009 and 2019 who underwent TR and 3 serial hip spica casts (18 weeks total) or who underwent SR with an open hip reduction via an anterior approach, combined with a Salter osteotomy of the pelvis and a femoral de-rotation with shortening at the same time. Pre and post-operative radiographs with a minimum 2 year follow-up were analysed, with complications and re-operations also recorded. Patients with syndromes associated with DDH or prior treatment for DDH were excluded.
Results: 12 patients (11 female) underwent SR (13 hips - 7 left) at a mean age of 30.3 months (range 14.2-56.5, SD 14.6), whilst 33 patients (29 female) underwent TR (37 hips - 23 left) at a mean age of 18.1 months (range 9.1-31.9, SD 6.0) (p < 0.0001). Mean inpatient hospital length of stay was 6.2 days for SR hips and 29.6 days for TR hips (p < 0.001). Avascular necrosis changes were observed in 25% of SR hips and 20% of TR hips at latest x-ray evaluation (p = 0.73). There were no unplanned surgeries in any of the SR hips. 51.3% of TR hips required follow-up surgery for residual DDH (19 pelvic osteotomies- 5 combined with proximal femoral osteotomies).
Conclusions: DDH discovered in the walking age child can be treated successfully with SR or TR reduction. TR in these patients is associated with a significantly higher inpatient hospital length of stay and rate of re-operation for residual DDH.
EP-18
The importance of monitoring and factors that may influence leg length difference in developmental dysplasia of the hip
1Norfolk and Norwich University Hospital, United Kingdom, 2Erasmus MC, Rotterdam, The Netherlands, 3Royal London Hospital, United Kingdom, 4Royal National Orthopaedic Hospital, United Kingdom
Introduction and Objective: Leg length discrepancy (LLD) in Developmental Dysplasia of the Hip (DDH) can arise due to avascular necrosis (AVN), osteotomies of the femur and acetabulum or residual dysplasia causing subluxation of the proximal femur. The aim of this study is to identify in patients with unilateral DDH; the prevalence of LLD, quantify which segment of the limb contributes to discrepancy and describe the influence of AVN on LLD. This study also tries to ascertain variables that may influence the need for LLD interventions. This would forewarn clinicians and better guide follow-up and management.
Materials and Methods: This was a consecutive retrospective case series study of patients with DDH. Long leg radiographs were calibrated and assessed at skeletal maturity. Measurements included Articulo-trochanteric distance (ATD), femoral length and tibial length. AVN was classified according Kalamchi-MacEwen. All surgical procedures for hip dysplasia and limb length discrepancy were documented.
Results: 109 patients met the inclusion criteria. The DDH leg was longer in 72/109(66%) patients. Majority of the segmental difference was in the subtrochanteric segment. Presence of AVN negatively influenced leg length. AVN was more common in patients with multiple procedures and older (≥ 3 year) age. In total 30 (27.5%) patients underwent a LLD intervention. The odds of needing a procedure to correct LLD was not influenced by type of surgery or grade of AVN. Lengthening of ipsilateral leg was required in patients with Type III and IV AVN.
Conclusions: LLD is higher in patients with DDH than the normal population. The DDH leg was usually longer in the subtrochanteric region with a trend towards femoral overgrowth after osteotomy and with multiple operative procedures. LLD interventions were required across all surgical groups and AVN grades. Our results underline the need for careful monitoring of LLD at appropriate stages in patients treated for DDH.
EP-19
A delayed imaging protocol for risk-factor based screening for developmental dysplasia of the hip reduces treatment rates: A COVID induced study
Anish Sanghrajka1, Rajiv Merchant1, Rachael Fisher1, Helen Chase1
1Norfolk & Norwich University Hospitals, Trauma & Orthopaedics, Norwich, United Kingdom
Introduction and Objective: The emergence of COVID-19 in 2020 meant that routine risk-factor based ultrasound screening for Developmental Dysplasia of the Hip (DDH) was ceased in our unit, and replaced with a Delayed Imaging Protocol (DIP), with either plain radiograph or ultrasound performed at about age 6 months. The purpose of this study was to investigate the impact this change in practice had on the incidence of Developmental Dysplasia of the Hip in our unit at this time point, and the impact on treatment rates for early DDH
Materials and Methods: This was a prospective cohort study of all babies referred to the DIP. Data collected demographic details, imaging modality, number of imaging episodes, evidence of DDH and whether treatment was required.
Results: Between July 2020 and November 2020, 162 babies were screened using the DIP. 98 were screened using plain radiographic imaging (AP pelvis) at mean age 7.04 months (range 5.6-12.9). 5 of these children had repeat radiograph 6 months later. 65 were imaged with ultrasound, (mean age 4.8 months; range 3.5-6.9). 4 of these children had a plain AP pelvis radiograph 6 months later. Only one subluxed hip was detected, and the child was treated in a semi-rigid abduction-orthosis. In 2020, our unit’s treatment rate for early DDH was 2.9/1000 live births, which is a reduction of 67% compared to 2019 (6.74/1000), and 62% reduction to 2018 (7.6/1000).
Conclusions: This study demonstrates the delayed imaging protocol for risk-factor based screening resulted in a significant reduction in treatment rates for early developmental dysplasia of this hip, without a corresponding increase in the rates of hip dysplasia, nor complexity of treatment. This study also demonstrates that ultrasound imaging of the hip can be used at least up to age 6 months without difficulty.
EP-20
Total hip arthroplasty followed by intramedullary femoral lengthening for staged reconstruction of unilateral neglected hip dislocation
Bjoern Vogt1, Robert Roedl1, Georg Gosheger2, Adrien Frommer1, Christoph Theil2, Gregor Toporowski1, Andrea Laufer1
1Pediatric Orthopedics, Deformity Reconstruction and Foot Surgery, 2General Orthopedics and Tumor Orthopedics, Muenster University Hospital, Muenster, Germany
Introduction and Objective: Neglected hip dislocation (NHD) can either occur congenitally, or secondary due to septic arthritis (SA) or trauma. Total hip arthroplasty (THA) is a successful approach to treat unilateral symptomatic NHD. However, the extensive leg length discrepancy (LLD) can hereby only be partially corrected. In case of residual LLD of more than 2 cm, subsequent femoral lengthening can be considered.
Materials and Methods: Retrospective analysis of clinical data and radiographs of five patients (age 38.1 (28-51) years) with unilateral NHD who underwent THA with (n = 3) or without (n = 2) subtrochanteric shortening osteotomy (SSO) and secondary intramedullary femoral lengthening through a retrograde magnetically-driven lengthening nail (follow-up 18.4 (15-27) months).
Results: LLD was 51.0 (45-60) mm before and 37.0 (30-45) mm after THA. Delayed bone union at one SSO site healed after revision with autologous bone grafting and plate fixation. Subsequent lengthening led to leg length equalization in all patients. Complete consolidation was documented in all lengthened segments.
Conclusions: Staged reconstruction via THA and secondary femoral lengthening can successfully be used to reconstruct the hip joint and equalize LLD. The specific anatomical conditions have to be taken into consideration when planning treatment, and patients ought to be closely monitored.
EP-21
Is the lateral cuneiform large enough to support interference screw fixation for tibialis anterior tendon transfer in children aged 3 to 6 years?
Jordan Polk1, Zachary Meyer2, Jacob Zide3, Yassine Kanaan1, Anthony Riccio1
1Orthopaedic Surgery, Texas Scottish Rite Hospital for Children, Dallas, USA, 2Orthopaedic Surgery, Washington University Medical Center, St. Louis, USA, 3Orthopaedic Surgery, Baylor Scott & White Hospital, Dallas, USA
Introduction and Objective: While transfer of the tibialis anterior tendon (TAT) to the lateral cuneiform (LC) is commonly performed for relapsed clubfoot deformity, modern methods of tendon fixation remain largely unstudied. Though interference screw fixation has the potential to obviate concerns of pressure necrosis and proper tendon tensioning associated with plantar button suspensory stabilization, a better understanding of LC morphology in young children is a necessary first step in assessing viability of this technique. The purpose of this investigation is therefore to define lateral cuneiform morphology in children aged 3-6 years.
Materials and Methods: A retrospective radiographic review of 40 healthy pediatric feet aged 3-6 years that had MRI or CT scans was performed. Length, width and height of the ossified portion of the LC were measured using sagittal, coronal and axial imaging. The maximal cross-sectional diameter of the TAT was measured at the level of the tibiotalar joint.
Results: Average ossified LC width ranged from 8.5mm in the 3-year-old cohort to 10.3mm in 6-year-old children. While the average width increased with each year of age, ANOVA testing revealed no significant difference in width between age groups (p = 0.091). Average ossified LC length ranged from 13.5mm in the 3-year-old cohort to 18.3mm in 6-year-old children with statistically significant increases in age all groups separated by two or more years (p = 0.017). The TAT to ossified LC width ratio ranged from 44% to 53% across age groups.
Conclusions: The ossification center of the LC is of sufficient width, height and length to accommodate a variety of commercially available interference screws in children aged 3-6 years. Assuming central bone tunnel preparation matching TAT diameter with line to line screw fixation, 47%-56% of the LC width and 70%-74% of the LC length would remain intact to circumferentially support interference screw fixation following TAT transfer.
EP-22
The Ponseti method for the treatment of clubfeet associated with Down syndrome
Edwin Portalatin-Perez1, Sarah Parenti2, Jordan Polk2, Chan-Hee Jo2, Anthony Riccio2
1Mayagüez Medical Center, Portorico, 2Scottish Rite for Children, Dallas, USA
Introduction and Objective: This study aims to compare treatment characteristics and outcomes of clubfoot patients with Down Syndrome (DS) to those with idiopathic clubfoot treated with the Ponseti method.
Materials and Methods: A retrospective review of prospectively gathered data was performed at a single institution over an 18-year period. Patients with idiopathic clubfeet and clubfeet associated with DS who were less than one-year old and treated by the Ponseti method were included. Initial Dimeglio score, number of casts, need for tendoachilles tenotomy, recurrence, and need for further surgery were recorded. Outcomes were classified using the Richards classification system.
Results: 24 clubfeet in 15 patients with DS, and 320 idiopathic clubfeet in 225 patients were identified. Average follow up was 62 months for the idiopathic cohort and 65 months for the DS cohort. DS patients presented for treatment at a significantly older age (54 vs. 16 days, p = 0.000) and with significantly lower average initial Dimeglio scores than the idiopathic cohort (11.1 vs. 13.7, p = 0.000). Tendoachilles tenotomy was performed in 79% of the idiopathic cohort and 75% of the DS cohort (p = 0.64). Recurrence rates were higher in the DS cohort (50%) than the idiopathic group (37%) but this difference was not statistically significant (p = 0.21). Need for later surgical procedures was similar between the two cohorts though recurrences in the DS group were significantly less likely to require intra-articular surgery (4.2% vs. 34.4%, p = 0.02). Clinical outcomes were 83% “good”, 13% “fair”, and 4% “poor” in DS patients, and 69% “good”, 27% “fair”, and 4% “poor” in the idiopathic cohort (p = 0.1).
Conclusions: Despite milder deformity and older age at presentation, DS associated clubfeet have similar recurrence rates and clinical outcomes as their idiopathic counterparts. When deformities do relapse in DS patients, significantly less intra-articular surgery is required than for idiopathic clubfeet.
EP-23
Interrelations between the too-long anterior calcaneal process, hind and mid-tarsal bone volumes, angles and osteochondral lesion of the dome of the talus. Analysis by software Slicer of 69 CT scan of feet
Giovanni Lucchesi1, François Bonnel2, Alain Dimeglio2, Giovanni Beltrami1, Federico Canavese3
1University Hospital Meyer, Firenze, Italy, 2University of Montpellier, Montpellier, France, 3Faculté de Médecine de l’Université de Lille Henri Warembourg, Loos, France
Introduction and Objective: No study has investigated the interrelations between Too-Long Anterior Calcaneal Process (TLACP), hind and mid-tarsal bones volumes and angles and the development of osteochondral lesion of the talus (OCL). The main goals of this work are: 1) to measure the volume of hind and mid-tarsal bones with and without TLACP; 2) to evaluate their angular relationships 3) to assess whether TLACP has an effect on the volume of OCL.
Materials and Methods: This is a study of 69 CT scans of 54 consecutive children aged 11- 15 years who had undergone a CT scan due to symptomatology suggestive of TLACP. The 3D Slicer software allowed to calculate the volume of the talus, calcaneum, navicular, cuboid, TLACP and OCL (in mm3). The PACS system was used to perform the angular measurements (in degrees) between talus, calcaneum and navicular in the frontal, axial and sagittal plane.
Results: The mean hind and mid-tarsal bone volumes of the TLACP group were comparable to those of the control group. There were 40 (81.6%) OCLs detected exclusively in pathological feet (TLACP group); 32 lesions were medial (80%), and 8 lesions were lateral (20%). According to Ferkel and Sgaglione CT Staging System, there were 22 (55%) stage 1 lesions, 5 (12.5%) stage 2 lesions and 13 (32.5%) stage 3 lesions. Only the angle between the talus and calcaneum in the frontal plane was significantly lower in pathological feet with respect to the control group (p < 0.001). In pathological feet, the talus was supinated, and the calcaneus pronated.
Conclusions: TLACP tend to stiffen the foot, modifying its biomechanics and leading to supination of the talus and pronation of the calcaneum. This induces an overpressure at the medial side of the talus where we observed a greater frequency of medial OCL with larger volume than lateral OCL.
EP-24
Participation and motor abilities in children with idiopathic clubfeet after treatment with the Ponseti method
Arnold Besselaar1, Lianne van Dijk2, Lianne Grin2,3, Saskia Wijnands1,2,3, Marieke van der Steen1,4, Benedicte Vanwanseele2,3
1Department of Orthopaedic Surgery & Trauma,Máxima MC, Veldhoven, The Netherlands, 2Fontys University of Applied Sciences, Eindhoven, The Netherlands, 3Human Movement Biomechanics Research Group, Faculty of Kinesiology and Rehabilitation Sciences, KU Leuven, Leuven, Belgium, 4Department of Orthopaedic Surgery & Trauma, Catharina Hospital, Eindhoven, The Netherlands
Introduction and Objective: Despite the large body of literature available on good initial outcomes of the Ponseti method in clubfoot treatment, far less is known about the functional long-term outcomes. Functioning in children consists of different aspects such as their ability to execute activities and participate in society. Several studies on clubfoot patients showed limited motor abilities and walking capacity compared to healthy controls, while another study showed comparable athletic abilities. As participation in daily life activities plays an important role in the development of children it is important to understand what problems clubfoot patients encounter. This study aims to determine the level of motor ability and participation in Ponseti treated clubfoot patients compared to age-matched healthy controls.
Materials and Methods: Parents of children aged between 5-9 years with and without idiopathic Ponseti-treated clubfeet were asked to fill out an online questionnaires about their child’s motor abilities and participation level including the Dutch version of the Assessment of Life Habits for Children (LIFE-H) version 3 to assess participation and the Dutch Movement Assessment Battery for Children-2 Checklist (MABC-2) for motor abilities. Statistical analysis focused on differences between groups.
Results: Questionnaires from 91 clubfoot patients (age 7.1, 74%boys) and 63 controls (age 6.7, 54%boys) were analysed. Results showed no significant differences between both groups on the total scores of the LIFE-H and the MABC-2. Clubfoot patients, however, showed lower scores on the subscale ‘movement in a static and/or predictable environment’. In addition, more clubfoot patients showed a higher risk for limited motor abilities.
Conclusions: In general, clubfoot patients showed high levels of motor ability and participation which were comparable to healthy age-matched controls. However, relatively more clubfoot patients showed a higher risk for deviating motor abilities. Future analyses will aim to investigate if these problems might be linked to a relapse.
EP-25
Atypical triplane fractures in adolescents: How much displacement is acceptable for conservative treatment?
Chaemoon Lim1
1Department of Orthopaedic Surgery, Jeju National University Hospital, Cheju, South Korea
Introduction and Objective: Atypical triplane fractures (ATFs) defined as a triplane fracture that did not involve the weight-bearing articulating surface or as an extra-articular triplane fracture. ATFs are scarcely reported and the incidence may be underestimated. Moreover, there is no consensus on treatment. This study aimed to evaluate ATFs incidence, fracture pattern, treatment outcome, and propose treatment recommendations.
Materials and Methods: 25 ATFs of 46 triplane fractures were retrospectively reviewed between 2011 and 2017. ATFs were classified according to the modified ATF classification. Treatment methods were analyzed. Radiologic outcomes were measured based on fracture displacement. Clinical outcomes included the American Orthopedic Foot and Ankle Society score, visual analogue scale, ankle range of motion, and complications at final follow-up period.
Results: A total of 11 type IV, 11 type III, and three type II ATFs were identified. All type II ATFs (intra-articular fracture) were treated with operative treatment. Five patients were treated with operative treatment and 18 patients were treated with non-operative treatment in type III or IV ATFs (extra-articular fracture). Good radiologic and clinical outcomes were observed in all patients. The residual displacement after initial trial of closed reduction was between 4 mm and 5 mm in 10 cases of type III or IV ATFs; however, no complications were observed, and all cases had good clinical results after non-operative treatment.
Conclusions: ATFs may be under recognized. Operative treatment and non-operative treatment showed good outcome. Non-operative closed reduction and cast immobilization can be recommended for extra-articular ATF with displacement < 4 mm.
EP-26
Location of sustentaculum tali on foot AP radiographs reduces the risk of subtalar joint articular facets damage in calcaneal lightening osteotomy
Sapogovskiy Andrey1, Vladimir Kenis1
1Foot and Ankle Surgery, The Turner Scientific Research Institute for Children’s Orthopedics, Saint-Petersburg, Russian Federation
Introduction and Objective: Calcaneal lengthening osteotomy is often used for flatfeet reconstruction. Different authors performed an osteotomy of the calcaneus at different distances from the calcaneocuboid joint. The ideal level for calcaneal osteotomy is considered to be between the medial and anterior facets of subtalar joint. On the other hand, some studies show a high risk of the subtalar joint facets damage during calcaneal osteotomy. We have developed a method for determining the level of sustentaculum tali on AP foot radiographs. Performing calcaneal osteotomy at the level of the anterior border of sustentaculum tali can reduce the risk of articular surfaces damage.
Materials and Methods: We evaluated 15 children (30 feet) without tarsal bones deformities who have foot radiographs and CT-scans performed for various reasons. Four researchers measured the distance between sustentaculum tali and calcaneocuboid joint level on the AP foot radiographs. An inter-rater reliability assessment was performed (ICC [95% СI]). The next stage of the study includes comparing the distance measurement between sustentaculum tali and calcaneocuboid joint according to AP radiographs and CT-scans. The significance of the differences was assessed using the Man-Whitney test. A correlation and regression analysis between measurement based on CT and radiographs were also carried out.
Results: There was no statistically significant difference in the determination of the sustentaculum tali level between AP radiographs and CT (p = 0.856). Intraclass correlation coefficient was 0.823 indicating high reproducibility of sustentaculum tali determination on AP foot radiographs. Pearson coefficient was 0.914. In regression analysis we find strong linear correlation, R2 was 0.835. This indicates that the determination of the sustentaculum tali on the AP radiographs corresponds to its real location.
Conclusions: Visualization of the sustentaculum tali on AP foot radiographs allows to determine the level of the calcaneal osteotomy and reduce the risk of damage to the articular surfaces.
EP-27
Objectively measured sleep metrics in infants and toddlers undergoing night-time boots and bar brace treatment for clubfoot compared to age matched controls
Charlotte Sununu1, Natalie Barnett2, Clare Kehoe3, David Scher4
1Hospital for Special Surgery Main Hospital, Pediatric Research, New York, USA, 2Nanit, New York, USA, 3Johns Hopkins University School of Nursing, Baltimore, USA, 4Hospital for Special Surgery Main Hospital, Pediatric Orthopedic Surgery, New York, USA
Introduction and Objective: Brace tolerance and the potential for impaired sleep is a major concern for caregivers of babies undergoing clubfoot treatment. The purpose of this study was to measure sleep outcomes of children wearing night-time boots and bar corrective braces and compare them to sleep metrics of historical controls.
Materials and Methods: The Nanit sleep monitoring system utilizes computer vision technology to measure and analyze sleep/wake patterns without direct patient contact. Patients 12-36 months undergoing nighttime boots and bar treatment, who slept alone in a crib, were eligible. The primary outcome, total sleep time (TST), and secondary outcomes sleep efficiency (TST/total time in crib), parental interventions, and night-wakings were recorded from the time the patient was placed in the crib at night until they were removed in the morning. Nine children were included in the study; recorded sleep metrics were compared to data from 75 age and geographically matched controls. Sleep data was collected for 4 weeks on consecutive nights. Shapiro-Wilk tests were performed on all data sets to assess normality. The Welch 2-sample t-test was utilized to evaluate differences in all sleep metrics. Statistical analyses were conducted using RStudio (R v4.1.0, RStudio v1.4.1717).
Results: Mean age of patients in the clubfoot and control groups were 23 months and 22.5 months, respectively. The clubfoot group was 44.4% female, and controls were 53.3% female. When total sleep time, mean sleep efficiency, parental interventions, and night-wakings were compared, no significant difference was found between study group and control group (p = 0.3644, 0.1528, 0.2244, 0.1494).
Conclusions: Preliminary results suggest that sleep outcomes while undergoing night-time boots and bar bracing is similar to that of controls. Going forward, a larger patient cohort will be required to identify subtle sleep alternations. Caregivers and physicians should feel reassured that clubfoot corrective bracing will not impact child sleep.
EP-28
Efficacy of various treatment strategies in severe Legg-Calve-Perthes disease: A network meta-analysis
1Foot and Ankle Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, x Bangkok, Thailand
Introduction and Objective: Several treatment methods for Legg- Calvé-Perthes disease (LCPD) were described according to previous literatures. However, no consensus was arrived regarding the best strategies for severe LCPD. This study intended to compare the efficacy of all treatment strategies for severe LCPD.
Materials and Methods: We searched PubMed and Embase up until July 2020 for studies which investigate LCPD treatment strategies efficacy. A network meta-analysis was performed to estimate the risk ratio (RR) and 95% confidence interval (CI) from both direct and indirect evidence for achieving spherical congruence of the hip joint after skeletal maturity in severe LCPD patients.
Results: We identified and included 25 comparative studies with 2486 affected hips for evidence synthesis. Combined osteotomy and femoral varus osteotomy were more efficacious than symptomatic treatment with statistically significance with RR = 2.51 (95%CI 1.14 to 5.51) and RR = 1.48 (95%CI 1.12 to 1.91) respectively. All treatment methods were ranked according to their efficacy for achieving spherical congruence hip based on the surface under the cumulative ranking (SUCRA) as followed: Combined osteotomy (0.9), femoral varus osteotomy (0.7), Salter innominate osteotomy (0.6), non-operative containment (0.4), Chiari osteotomy (0.2), and symptomatic treatment (0.1).
Conclusions: Combined osteotomy and femoral varus osteotomy demonstrate superior efficacy in achieving spherical congruence hip compared to symptomatic treatment for severe LCPD patients based on current evidence.
EP-30
The optimized oxford hip skeletal maturity system proves resilient to rotational variation
Julio Castillo Tafur1, Ryan Furdock1, Abdus Sattar2, Raymond Liu1
1Department of Orthopaedic Surgery, Rainbow Babies and Children’s Hospital at Case Western Reserve University School of Medicine, Cleveland, USA, 2Case Western Reserve University School of Medicine, Department of Population and Quantitative Health Sciences, Cleveland, USA
Introduction and Objective: The recently described optimized Oxford skeletal maturity system utilizes anteroposterior (AP) hip radiographs to accurately, rapidly, and reliably estimate skeletal maturity. However, in the real-world setting, significant positional variation in AP hip radiographs may influence the accuracy of optimized Oxford skeletal age estimates. We sought to evaluate the consistency of skeletal age estimations using the Optimized Oxford system between differently rotated radiographs.
Materials and Methods: Thirty normal computerized tomography (CT) scans of males (15 children, 9 to 15 years) and females (15 children, 8 to 14 years) were obtained retrospectively, converted into 3D reconstructions and then used to produce simulated hip radiographs in five different rotational positions. The optimized Oxford system was applied to the 150 simulated AP hip radiographs (5 differently rotated views of 30 hips) to produce a skeletal age estimate for each. One-way repeated measures ANOVA was used to compare optimized Oxford skeletal age estimations on the centered hip view versus the other four rotated positions.
Results: Rotational position did not have a statistically significant effect on the skeletal age (p = 0.84) using one-way repeated measures ANOVA. Of the five radiographic parameters in the optimized Oxford system, only greater trochanter height showed significant rotational variation after Greenhouse-Geisser correction (F (2.58, 74.68) = 5.98, p < 0.001). However, post-hoc analyses showed that the greater trochanter height obtained at the most centered position was not different from the other four rotational positions (p > 0.05 for all).
Conclusions: The optimized Oxford skeletal maturity system is resilient to rotational variation. Mildly to moderately rotated radiographs obtained in the modern clinical setting can be used for skeletal age estimation by this method, broadening the clinical usage of this system.
EP-31
Long term follow-up (35 years) of untreated patients with idiopathic increased femoral anteversion
Anders Grønseth1, Suki Liyanarachi2, Joachim Horn1, Terje Terjesen1
1Children’s Orthopaedics and Reconstructive Surgery, Division of Orthopaedic Surgery, Oslo University Hospital, Oslo, Norway, 2Department of Orthopaedic,St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
Introduction and Objective: Treatment of idiopathic increased femoral anteversion (AV) has been a controversial topic. Several studies have shown a spontaneous decrease of the AV angle during childhood, leading to stricter indications for surgical correction. There is, however, limited knowledge about the long-term consequences of persisting increased AV. The purpose of our study was therefore to examine function and radiographic outcome in untreated patients with > 30 years follow-up.
Materials and Methods: Patients were recruited from a former study on the natural course of increased femoral AV in children. Inclusion criterion was untreated persisting AV angle ≥ 30°, verified by CT measurements. Outcome measures were the subscores of pain and symptoms of The Hip And Groin Outcome Score (HAGOS), signs of hip osteoarthritis defined by joint space width < 2 mm, and the foot progression angle. A control group of 14 individuals was examined using the same methods.
Results: 16 patients (15 females) with a mean age of 46.8 years (37-50) were included in the study. The mean follow-up after initial examination in childhood was 35.1 years (32-39). The control group had a mean age of 46.2 years (35-61). The mean AV angle was of 39.4° (29-53) in the study group and 24.4° (18-30) in the control group (p < 0.001). HAGOS pain score in the study group was 89.5 and 96.4 in the controls (p = 0.079). HAGOS symptom scores were 84.4 and 91.9, respectively (p = 0.128). The mean foot progression angle was 1.4° in the study group and 5.5° in controls.
Conclusions: Untreated patients with increased femoral AV and a follow-up of > 30 years had lower scores for HAGOS pain and symptoms and lower foot progression angle than the control group. These findings were not statistically significant, probably due to relatively few patients in both groups.
EP-32
Hip morphology in periacetabular osteotomy (PAO) patients treated for developmental dysplasia of the hip (DDH) as infants compared to those without infant treatment
Bridget Ellsworth1, Joshua Bram1, Ernest Sink1
1Hospital for Special Surgery, New York, USA
Introduction and Objective: A subset of patients successfully treated for DDH as infants have symptomatic acetabular dysplasia at skeletal maturity requiring PAO. The purpose of this study was to compare femoral and acetabular morphology in PAO patients with late acetabular dysplasia after previous treatment for DDH with PAO patients who do not have a history of DDH treatment.
Materials and Methods: A single surgeon’s patients who underwent PAO between 2011 and 2021 were retrospectively reviewed. Patients previously treated for infantile DDH with a Pavlik harness, abduction brace, closed reduction and spica casting, or open reduction and spica casting were included. Patients with previous bony hip surgery were excluded. Pre-operative radiographic measurements of each hip were recorded including lateral center edge angle (LCEA), anterior center edge angle (ACEA), and femoro-epiphyseal acetabular roof (FEAR) index. CT measurements included the coronal center edge angle (CCEA), sagittal center edge angle (SCEA), Tönnis angle, acetabular anteversion at 1, 2, and 3 o’clock (AV1, AV2, AV3), femoral neck-shaft angle (NSA), femoral version (FV), and alpha angle. Control PAO cases without a history of DDH diagnosis or treatment were matched with the infantile DDH treatment group in a 2:1 ratio based on CCEA, age, and sex.
Results: There were 21 hips in 18 patients previously treated for infantile DDH. The control PAO cohort was 42 hips in 42 patients who did not have previous DDH treatment. There was no statistically significant difference in any of the recorded measurements between patients previously treated for DDH and those without previous treatment including FV (p = 0.494), AV1 (p = 0.820), AV2 (p = 0.584), AV3 (p = 0.137), NSA (p = 0.612), and LCEA (p = 0.433).
Conclusions: Femoral and acetabular morphology is similar between PAO patients with persistent symptomatic acetabular dysplasia following DDH treatment and patients presenting after skeletal maturity with acetabular dysplasia and no previous history of DDH treatment.
EP-34
The mini open approach for the correction of femoralacetabular impingement after a slipped upper femoral epiphysis is effective and reproducible
Karim Masrouha1, Pablo Castaneda1, Leon Moscona Mishy1, Salim Habib2
1Department of Orthopedic Surgery, NYU Langone Health, New York, USA, 2Division of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, USA
Introduction and Objective: The most significant contributor to femoroacetabular impingement (FAI) in adolescence is slipped upper femoral epiphysis (SUFE); the CAM deformity of the proximal femur is almost ubiquitous after even a mild slip. If FAI becomes symptomatic, surgical treatment may be indicated; however, the surgical approach is debated. The objective was determine if the mini-open approach to treat FAI after SUFE is a reproducible approach that can provide pain relief and improved hip function.
Materials and Methods: This is a retrospective review of prospectively collected data on 26 patients who underwent a mini-open repair of post-SUFE FAI at one of two centres, with a minimum two-year follow-up. All patients had a history of a grade III SUFE and had FAI symptoms at presentation.
Results: Preoperative pain using the visual analog scale was recorded at a mean of 6.2 and went down to 0.004 two years after surgery. Hip function improved significantly, going from a mean modified Harris Hip Score of 78.8 preoperatively to 93.2 at two years (p = 0.000). Radiographically, the mean Alpha angle was 58.5° preoperatively and 48.9° at the two-year follow-up (p = 0.000). There were no cases of avascular necrosis and no significant complications.
Conclusions: The mini-open approach for treating symptomatic femoral acetabular impingement is safe and provides a significant improvement in pain and function in the short term.
EP-35
Testing a new surgical principle of guided growth for correction of rotational deformity of long bones in children
Andreas Peter Balslev-Clausen1, Klaus Hindsø2, Peter Buxbom3, Christian Wong4
Introduction and Objective: Corrections, using osteotomies and plates or frames, for angular and rotational deformity of the lower extremity are large surgical procedures with risk of complications, but they can be necessary for amending the subsequent gait disturbances, pain and decreased function caused by the deformity. Guided growth are used for correcting angular deformities in the growing pediatric patients, but the technique have not been used for rotational deformities in humans. So far only animal studies have been published and this study investigates if guided rotation is possible in children.
Materials and Methods: Five children (9 bone segments) with symptomatic rotational deformities were included after informed consent in a prospective cohort. Using intraoperative dynamic radiographs, Pediplates® were inserted across the growth plate in a 45 degree (dg.) angle on both sides of either the femoral and/or tibial physes of the knee. RSA beads were inserted systematically, and patients were followed up every three months with radiostereometric analysis.
Results: At 9.3 months follow up, there was an average of 5.5 dg. (range 0-12 dg.) of derotation and a longitudinal growth of 8.4 mm. (range 2.8-13 dg.). However, the first two patients (4 segments) showed minimal derotation and growth after 6 months, whereas the later three patients (5 segments) showed an average rotation of 9.3 dg. and 9.4 mm of growth. A rebound effect of 2.49 dg. was demonstrated in two children after plate removal at an average of 9.9 months.
Conclusions: The principles of guided growth can be applied for rotational deformity in growing children. In principle, this can be utilized to correct rotational deformities with minimal morbidity and discomfort. Exact plate placement of plates is crucial and a rebound effect is to be expected.
EP-36
How are pre-operative surgeon and patient expectations related to patient-reported outcomes after periacetabular osteotomy?
Samantha Ferraro1, Patricia Miller1, Michael MIllis1
1Boston Children’s Hospital, Boston, USA
Introduction: This study is intended to compare pre-operative surgeon and patient expectations to post-operative patient-reported outcomes for patients undergoing a periacetabular osteotomy (PAO).
Methods: Patients aged 14 or older who underwent a PAO from 2012 to 2014 were asked to complete a pre-operative questionnaire on their expected improvement in six domains (locking/catching, pain, sports participation, stability, stiffness, walking ability) as well as short-term and long-term follow-up questionnaires to collect patient-reported outcomes. Surgeons also completed a pre-operative questionnaire about their expectations for the patient.
Results: The patient cohort consists of 115 patients who underwent PAO surgery at an average 26.3 years (SD, 9.6; range, 11.8-47.3). Sixty-seven patients responded to a short-term follow-up questionnaire at a median 8 months (IQR, 6.5-12.1) after their PAO, which assessed their fulfilment of expectations and satisfaction with the surgery. In each domain, patients most commonly reported that they were “very satisfied” and had post-operative results that were “just as suspected.” The sports participation domain had the highest proportion of patients who reported results that were “not as expected” (21%) and who were “very dissatisfied” (17%). Sixty patients responded to a long-term follow-up questionnaire at a median 7.8 years (IQR, 7.5-8.4) after their PAO, which assessed their perceived degree of improvement in each of the six domains. Partial agreement between patient pre-operative expectations and long-term outcomes was moderate to substantial across all domains (kappa = 0.54-0.75). When comparing surgeon pre-operative expectations to long-term outcomes, partial agreement was moderate to substantial for only the sports participation (kappa = 0.49) and pain domain (kappa = 0.64).
Conclusions: Within the first year after a PAO, patients tend to have outcomes just as they suspected and are very satisfied with their surgery. Notably, the long-term follow-up questionnaires suggest that patients may be better at predicting long-term post-operative outcomes than their surgeons.
EP-37
Hip instability in children with trisomy 21
Milud Shadi1, Pawel Glowka1, Marek Jóźwiak2, Tomasz Kotwicki1
1Department of Spine Disorders and Pediatric Orthopedics, University of Medical Sciences, Poznan, Poland, 2Department of Paediatric Orthopaedics and Traumatology, University of Medical Sciences, Poznan, Poland,
Introduction and Objective: Hip instability occurs in 2% to 5% of patients with Down syndrome despite normal
acetabular morphology. The aim of the study was to evaluate the results of treatment of hip instability in children with trisomy 21.
Materials and Methods: 11 hips, 6 patients with trisomy 21, aged from to 12 years (mean 7.0, SD 2.9) were operated on because of habitual hip dislocation (2 patients), hip subluxation (1) and permanent hip dislocation (3). Walking difficulty, joint instability, pain, discomfort or fear of dislocation were the clinical problems. Posterior dislocation was observed in all patients. The following procedures were performed: 11 open hip reductions, 4 Dega’s reverse transiliac osteotomies, 3 Dega’s transiliac osteotomies, 2 triple pelvic osteotomies, 9 proximal femoral derotational osteotomies, 4 joint capsule duplications, 2 femoral head ligament augmentations. Hip spica cast was applied for 6 weeks. Based on the pre- and post-surgery X-rays acetabular index and Reimer’s migration index were measured.
Results: Stable hip joint was achieved in all patients. All patients walk independently, without any complaints. The acetabular index before surgery ranged from 15.0 to 27.0 (mean 19.2, SD 3.7), after surgery from 2.0 to 18.0 (mean 11.5, SD 5.4). Preoperative Reimer’s migration index ranged from 0% to 100.0% (mean 57.7%, SD 34.9%), after surgery from 0% to 20.0% (mean 6.5%, SD 9.2%). Anchor loosening was observed in one case requiring its removal.
Conclusions: Hip instability in patients with Down syndrome can be success treated. The surgery requires an individually selected, surgical technique, including procedures on soft and bone tissues, taking into account the patomechanism of hip instability.
EP-38
An anatomic study of the proximal tibial epiphysis with relevance to percutaneous epiphysiodesis using transphyseal screws (PETS)
Michael Do1, Conor McCarthy1, Daniel Cooperman1, Raymond Liu1
1Rainbow Babies and Children’s Hospital, Cleveland, USA
Introduction and Objective: A potential complication of PETS is development of tibial valgus deformity, which may occur secondary to decreased screw purchase in the thinner medial proximal tibial epiphysis. The thickness of the proximal tibial epiphysis has not yet been well quantified.
Materials and Methods: Three-dimensional surface scans of 32 cadaveric proximal tibial epiphyses in specimens aged 3 to 17 years old were obtained and computer modeling software was utilized to measure the thickness of the proximal tibial epiphysis at 20 standardized potential screw insertion points according to a generated 5x4 map. In the sagittal plane, 5 markers were set at 0 (midline), 10%, and 20% of the total physeal length away from midline in the anterior and posterior directions, and in the coronal plane, 4 markers total were set at 25% and 33% of the total physeal width away from the medial and lateral edges (Figure 1).
Results: When normalized to the total width of the proximal tibial epiphysis, the lateral side is thicker compared to the medial side (Figure 2). The positions with the greatest thickness are located at the midline in the sagittal plane and 33% of the total width away from the medial and lateral edges in the coronal plane (0.265 and 0.261 normalized thickness, respectively). The proximal tibial epiphysis is particularly thin 25% from the medial edge (normalized thickness range: 0.196-0.221). Multiple regression analysis revealed a significant relationship between increasing age and female sex with thinner normalized medial and lateral heights.
Conclusions: During PETS, screws should be positioned centrally in the sagittal plane and 33% of the total width away from the medial and lateral edges of the proximal tibial epiphysis in the coronal plane to obtain greater screw purchase. Caution is advised when inserting screws in the medial 25% of the proximal tibial epiphysis.
EP-39
Femur lengthening over nail in adolescents: Is the lateral shift of the mechanical axis inevitable?
Kyeong-Hyeon Park1, chang-wug Oh2
1Orthopedic Surgery, Kyungpook National University Chilgok Hospital, Daegu, South Korea, 2Orthopedic Surgery, Kyungpook National University Hospital, Daegu, South Korea
Introduction and Objective: The theoretical risk of medialisation of the knee joint and the lateral shift of the lower extremity mechanical axis due to lengthening along the anatomical axis is present in femoral lengthening over the nail technique. We aimed to determine whether femoral lengthening over the nail (LON) in adolescents has an inadvertent effect on lower limb alignment.
Materials and Methods: Femoral LON using monolateral distractor was performed in 29 femora in 29 patients (mean age 14.3 years (9 to 18)). Patients who underwent simultaneous realignment procedures or concurrent tibial lengthening or who developed mal- or nonunion were excluded. Pre-operative and post-lengthening radiographs were used to measure lower limb alignment.
Results: The mean lengthening achieved was 4.9 cm (2.6 to 8.3). The pre-operative and post-lengthening m-LDFA was average 88.4 (± 5.85) degrees and 87.9 (± 5.94) degrees (p > 0.05). The pre-operative and post-lengthening mechanical axis deviation (MAD) was on average 0.98 (± 20.01) mm and 4.03 (± 22.84) mm (p < 0.05). The average angle of proximal and distal femur shaft between was increased from varus 0.1 (± 3.7) degrees to varus 3.3 (± 5.2) degrees (p < 0.05). In 26 of 29 limbs, the mechanical axis shifted laterally by a mean of 1.4 mm/cm of lengthening (0 to 5.5).
Conclusions: In adolescents, femur lengthening over nail results in a lateral shift of the mechanical axis by approximately 1.4 mm for each 1 cm of lengthening. And it is thought to have little effect on mechanical axis deviation in adolescents.
EP-40
Drop landing analysis of rotational osteotomies
Peter Stevens1, Bruce Macwilliams1
1University of Utah Hospital, Salt Lake City, USA
Introduction and Objective: Persistent and symptomatic long bone torsion may warrant rotational osteotomy. By studying drop landing mechanics in subjects with pathological rotation alignment, we documented the negative biomechanical impacts on the knee joint, and the mitigation of these following rotational osteotomy
Materials and Methods: We performed drop landing analysis, preoperatively and following rotational osteotomy, on 3 cohorts of patients having: 1) femoral anteversion (FA, N = 12) 2) outward torsion (TT, N = 13) 3) pangenu (PG, N = 12). A fourth, age matched cohort, having no torsion, served as the control (TD, N=25). The mean age at surgery (initial surgery for staged procedures) ranged from 12.1 (FA) to 14.2 (PG) years. Subjects were predominately female in each group, including 30/37 (81%) of all limbs evaluated. The mean torsion in the TT and PG groups was 360 and 370. The mean femoral anteversion in the FA and PG groups was 310 and 330. Subjects completed a series of 5 drop landing maneuvers from a 30 cm. high bench, landing with feet on adjacent force plates. Motion data were collected at 100 Hz and force plate data at 1000 Hz. Trial data were averaged for each subject.
Results: FA and PG groups used compensatory hip rotation strategies to correct knee position. Elevated lateral knee forces, and valgus knee moments were still present preoperatively and were normalized following correction of malrotation. Anterior knee forces were decreased in TT compared to TD, and even more decreased after corrective osteotomy.
Conclusions: Adolescents with FA, TT, or PG may not always be able to compensate and therefore be more vulnerable to injury. Preoperative drop jump analysis provides objective evidence of the pathophysiology and risks of persistent torsion as well as the benefits of corrective osteotomy. This evidence may convince therapeutic nihilists that surgical treatment is warranted in a select population.
EP-41
Tension band plating for correction of leg length difference
1Erasmus MC Sophia Kinderziekenhuis, Rotterdam, The Netherlands, 2Royal National Orthopaedic Hospital, United Kingdom, 3Norfolk & Norwich University Hospital, United Kingdom, 4Great Ormond Street Hospital for Children, United Kingdom, 5University College London, United Kingdom
Introduction and Objective: Dual tension band plates are used as a means of temporary epiphysiodesis for longitudinal guided growth. The study aim was to assess rate of correction, identify development of femoral and tibial intra-articular deformity during correction, and document resumption of growth after plate removal.
Materials and Methods: We performed a retrospective cohort study of 34 consecutive patients treated with dual tension band plates between 2012 and 2020: 24 at the distal femur, 6 at the proximal tibia and 4 at both. 25 female patients were operated on at a mean age of 11.6 (± 1.4) years and 9 male patients at 13.5 (± 1.5) years. Measurements were performed on standardised long-leg radiographs and included LLD, joint line congruency angle, tibial roof angle, femoral floor angle and notch-intercondylar distance. Measurements were taken pre-operatively, at the end of length correction and at most recent review or skeletal maturity.
Results: LLD was reduced by a mean of 12.9mm (95%CI 10.2-15.5), mean residual difference was 8.4mm (95%CI 5.4-11.4). The mean correction rate for the proximal tibia was 0.40 (SD0.33) mm/month and 0.68 (SD0.36) mm/month for the distal femur. Only at femoral level, was a significant mean change in residual LLD (-2.5 mm (95%CI 0.7-4.2) observed between plate removal and skeletal maturity. After length correction, the tibial roof angle showed a significant between leg difference of 8.4° (95%CI 13.4-3.4). In femoral epiphysiodesis patients, no such differences were observed.
Conclusions: A significant reduction in LLD can be achieved using dual tension band plating. Change in intra-articular morphology was observed only in the proximal tibia and not in the distal femur. In the authors opinion tension band plating is a useful tool for younger patients or when residual growth is difficult to predict.
EP-42
Morphology of the knee joint after tension-band plating
Emma Julie Hvidberg1,2, Maria Kirstine Møller-Madsen2, Jan Duedal Rölfing1,2, Bjarne Moeller-Madsen1,2, Ahmed A. Abood1,2,3
1Department of Orthopaedics, Aarhus University Hospital, Aarhus N, Denmark, 2Danish Paediatric Orthopaedic Research, Aarhus N, Denmark, 3Department of Orthopaedics, Aalborg University Hospital, Aalborg, Denmark
Introduction and Objective: The use of tension-band plating, i.e. eight-plates is commonly used to correct coronal angular limb deformities in children. The technique consists in tethering of the physis peripherally while allowing the rest of the physis to grow normally. Changes in joint morphology have been observed after epiphysiodesis using eight-plates. Therefore, it seems relevant to investigate if joint morphology also changes after temporary hemiepiphysiodesis. The objective is to evaluate potential changes in knee joint morphology after treatment of coronal angular limb deformities with eight-plates.
Materials and Methods: A retrospective study was performed on radiographs of 39 children (71 knees). All patients undergoing temporary medial hemiepiphysiodesis using eight-plates between 2015 and 2020 were included. Anteroposterior knee radiographs of all patients were reviewed. The patients were assigned into two groups, tibial and femoral group according to anatomic insertion of the eight-plates. Medial and lateral slope angles of the tibial plateau, tibial roof angle and femoral notch angle were measured. Mean differences between pre-operative and post-operative values were estimated with corresponding confidence intervals and p-values.
Results: 75 eight-plates were identified (femur 68, tibia 7) in 39 children. Mean insertion time was 13 months (95% CI: 12; 14). Mean change of medial tibial and lateral slope angles was 0.45° (-1.83; 2.74) and 0.79° (-1.63; 3.2). Mean difference in roof angle was -1.24° (-2.77; 0.28) in the tibial group. Mean change in femoral notch angle was -1.2° (-3.3; 0.91). ICC value for the femoral notch angle was 0.64 (0.17; 0.97).
Conclusions: No alterations of the knee joint morphology were observed after temporary hemiepiphysiodesis with the insertion of eight-plates. It is safe to use eight-plates for hemiepiphysiodesis when correcting coronal limb deformities in children without changing the knee joint morphology.
EP-43
Our experience of treatment of congenital pseudoarthrosis of tibia using X-union protocol
Petr Vvedenskiy1, Maxim Vlasov1
1Pediatric Orthopaedics, Privolzhskiy Research Medical University, Nizhny Novgorod, Russian Federation
Introduction and Objective: According to the literature the rate of recurrence of pseudarthrosis of tibia with the use of different treatment techniques is up to 68%. When the compression-distraction method is combined with intramedullary nailing the frequency of recurrence decreases to an average of 17%. The “X-union” protocol proposed by D. Paley gives 100% of primary union and no recurrence of pseudoarthrosis according to author. This paper presents our experience in treatment of patients with congenital pseudarthrosis of tibia using the “X-union” protocol.
Materials and Methods: We analyzed 10 patients with a congenital pseudarthrosis of tibia who underwent surgical treatment according to the “X-union” protocol proposed by Dr. Paley. The only deviation from this protocol was that we didn’t used BMP sponge. Instead of it we used the “X-factor” in three patients. The age of patients varied from 1.5 to 7 years. In six patients the pseudarthrosis was caused by neurofibromatosis, in one by fibrous dysplasia. Seven patients had type 4B pseudarthrosis, two had type 3 and one - type 4A.
Results: Consolidation of tibia occurred in all 10 patients. Consolidation of fibula did not occur in three patients thus instead of an X-shaped synostosis a Y-shaped synostosis was obtained. All patients gained ability of weight-bearing within the affected limb. No recurrence of pseudarthrosis was noted for a follow-up period of up to 3 years.
Conclusions: The technology of treatment of congenital pseudarthrosis of tibia according to the “X-union” protocol allows to achieve consolidation of tibia and fibula with formation of tibiofibular synostosis. When performing a surgery special attention should be paid to osteosynthesis fibula and autograft plastics around the fibula fragments to ensure consolidation. Taking into account the tendency to valgus deformity of tibia in most patients it is probably make sense to perform slight varization of tibia.
EP-44
Bone age assessment by 3 methods. A comparison of 3 different methods for assessment of skeletal age when treating leg length discrepancies: An inter- and intra-observer study
Anne Breen1, Joachim Horn1, Harald Steen1, Are Pripp2, Ragnhild Gunderson3, Else Merckoll3, Ivan Hvid1, Wajeeha Zaidi4, Hilde Kristine Sandberg Mentzoni4
1Division of Orthopaedic Surgery, Oslo Universitetssykehus Rikshospitalet, Norway, 2University of Oslo, Norway, 3Division of Radiology, Oslo Universitetssykehus Rikshospitalet, Norway, 4Akershus University Hospital, Norway
Introduction and Objective: Skeletal maturity is a crucial parameter when calculating remaining growth in children. 3 different methods, 2 manual and 1 automated were used in the radiological assessment of bone age with respect to precision and systematic difference.
Materials and Methods: 66 simultaneous examinations of the left hand and left elbow from children treated for leg length discrepancies were randomly selected for skeletal age assessment. The radiographs were anonymized and assessed twice with at least 3 weeks interval according to the Greulich and Pyle (GP) and Sauvegrain (SG) methods by 5 radiologists with different level of experience. The hand radiographs were also assessed for GP bone age by use of the automated BoneXpert (BX) method for comparison.
Results: The inter-observer Inter Class Correlation (ICC) was 0.96 and 0.98 for the GP and SG method, respectively. The inter- and intra-observer Standard Error of the Measurement (SEM) was 0.41 and 0.32 years for the GP method and 0.27 and 0.21 years for the SG method with a significant difference (p < 0.001) between the methods and between the experienced and the less experienced radiologists for both methods (p = 0.003 and p < 0.001). In 25% of the assessments the discrepancy between the GP and the SG method was > 1 year. There was no systematic difference comparing both manual methods with the automatic BX method.
Conclusions: With respect to the precision of skeletal age determination, we recommend using the SG method or preferably the automated BX method based on GP assessments if available in the calculation of remaining growth
EP-46
MPLF reconstruction and hemi-epiphysiodesis for patellar instability with genu valgum
Dayna Philips1, Matthew Veerkamp1, Eric Wall1, Matthew Ellington2, Nicole Friel3, John Schlechter4, Daniel Green5, Javier Masquijo6, Shital Parikh1
1Cincinnati Children’s Hospital Medical Center, Cincinnati, USA, 2Central Texas Pediatric Orthopedics: Central Austin, Austin, USA, 3Shriners Hospitals for Children - Northern California, Sacramento, USA, 4CHOC Children’s Main Campus Orange, Orange, USA, 5Hospital for Special Surgery Main Hospital, New York, USA, 6Sanatorio Allende, Córdoba, Argentina
Introduction and Objective: Failure rate of isolated MPFLR in skeletally immature is higher than adults. The study aims to evaluate outcomes of combined MPFL Reconstruction (MPFLR) and implant mediated guided growth (IMGG) in skeletally immature patients with patellar instability and genu valgum.
Materials and Methods: In a multicenter study, 31 patients (37 knees) underwent MPFLR and IMGG with eight-plate or transphyseal screw. Radiographic and clinical outcomes were analyzed.
Results: Mean age 12.4 years (± 2.2). Skeletal age 12.9 years (± 1.8). MRI showed patella alta (CDI 1.4 ± 0.3), TT-TG 16.7 mm ± 5.6, patellar tilt 18.6° ± 8.3, trochlear depth 3 mm ± 1.4. Simultaneous MPFLR and IMGG performed in 26/37; 11 underwent staged procedures. 20 plates (13 femur, 1 tibia, 3 both) and 22 screws (14 femur, 4 tibia, 2 both) used. Valgus corrected from 12.7° (± 4) to 2.5° (±4.1) in 11.6 months (±6.3). 22/37 had implants removed; 13 had retained implants at maturity. No difference in valgus correction rate between plates (0.63°/month) vs screw (0.6°) but preoperative valgus was significantly different (15.2° vs 11°, p=0.001).There was no difference in correction rate between staged (0.68°/month) vs simultaneous (0.62°) surgery but preoperative valgus was significantly different (15.5° vs 11.4°, p = 0.004). There was significant difference in threshold value for valgus correction between institutions (15.1° vs 10.5°, p = 0.0005). Revision surgery required for 5/37 (13.5%) re-dislocations and 1 arthrofibrosis. Complications from IMGG: 2 rebound valgus > 5°, 6 overcorrection (1-5° varus) and one plate loosening requiring premature removal. 4/6 knees in children < 10 yrs age had 5 complications (3 re-dislocations, 2 overcorrection). All 5 re-dislocations occurred in 3/6 patients with bilateral procedures.
Conclusions: MPFLR and IMGG had acceptable outcomes with 13.5% re-dislocation. Children < 10 yrs and bilateral instability with genu valgum remain difficult subsets to treat that may require treatment modification.
EP-47
Lengthening of the femur in adolescents with congenital diseases - comparison of three different techniques
Szymon Pietrzak1, Dariusz Grzelecki2, Tomasz Parol1, Jaroslav Czubak1
1Dept. of Orthopaedics, Paediatric Orthopaedics and Traumatology, 2Dept. of Orthopaedics and Rheumoorthopaedics, Centre of Postgraduate Medical Education, A. Gruca Orthopaedic Hospital, Otwock, Poland
Introduction and Objective: The aim of this study is to evaluate the course of the treatment, clinical and functional outcomes of femur lengthening without axial and rotational deformity in adolescents with congenital disorders by the application of different methods: 1) intramedullary growing nail; 2) monolateral external distractor, and 3) computer-assisted circular external fixator.
Materials and Methods: This retrospective study comprised 35 patients (39 procedures): 11 intramedullary magnetic nails (IMN) Precise 2 (NuVasive, San Diego, California, USA), 11 monolateral external distractors Modular Rail System (MRS) (Smith and Nephew, Memphis, Tennessee, USA) and 17 external fixators Taylor Spatial Frame (TSF) (Smith and Nephew, Memphis, Tennessee, USA). The inclusion criteria were stated as congenital femoral length deficiency without any axial deformities, and independently of the finally applied treatment, technical possibility for use each of the analyzed methods.
Results: A distraction index did not differ significantly between the groups (p = 0.89). The median lengthening index was the lowest in the IMN group (24.3 d/cm; IQR 21.8 - 33.1) statistically different in comparison to the MRS (44.2 d/cm; IQR 42 - 50.9; p < 0.001) and the TSF group (48.4 d/cm; IQR 38.6 - 63.5; p < 0.001). Similarly, the consolidation index in the IMN group (12.9 d/cm; IQR 10.7 - 21.3) was the statistically lower than in the MRS (32.9 d/cm; IQR 30.2 - 37.6; p < 0.001) and the TSF (36.9 d/cm; IQR 26.6 - 51.5; p < 0.001) groups.
Conclusions: This study indicates IMN more valuable method of treatment for femoral length discrepancy without axial deformity than MRS and TSF in complication rate and indexes of lengthening and consolidation.
EP-48
Many radiologic indices for patellofemoral instability are unreliable
Peter Fabricant1, Madison Heath1, Douglas Mintz1, Kathleen Emery2, Matthew Veerkamp2, Simone Gruber1, Daniel Green1, Eric Wall2, Marc Tompkins3, Benton Heyworth4, JUPITER Study Group2, Beth Shubin Stein1, Shital Parikh2
1Hospital for Special Surgery Main Hospital, New York, USA, 2Cincinnati Children’s Hospital Medical Center, Cincinnati, USA, 3TRIA Orthopedic Center Bloomington, Bloomington, USA, 4Boston Children’s Hospital, Boston, USA
Introduction and Objective: Medical decisions and prognosis for patients with patellofemoral instability (PFI) relies heavily on anatomic risk factors which are measured on radiographs and MRI. In order to be clinically useful, imaging parameters must demonstrate acceptable interrater reliability. The purpose of this study was 1) to evaluate the interrater reliability of common radiographic parameters used for decision making process in PFI, and 2) to attempt to improve reliability for measurements that demonstrate unacceptable interrater reliability.
Materials and Methods: Common imaging parameters for PFI that have been published and their definitions were compiled. Two musculoskeletal radiologists assessed radiographs and MRI of 50 patients for PFI measures. Intraclass Correlation Coefficients (ICC) were calculated for each measurement. For those measurements demonstrating unacceptable interrater reliability (ICC < 0.6), authors discussed consensus methods to improve reliability and then examined 20 images from a separate set of subjects. If reliability was still low after the second round of assessment, the measure was considered unreliable.
Results: Of the 50 selected participants, 28 (56%) were female; mean age was 14 ± 2 years. Interrater reliability for 5 radiographic and 7 MRI assessments was initially acceptable, 4 radiographic and 2 MRI assessments improved after consensus training, and 6 radiographic and 3 MRI assessments remained unreliable after consensus training (
Table 1
). Radiographs were acceptable for evaluation of Caton Deschamps Index and leg length discrepancy / alignment. MRI was acceptable for evaluation of trochlear dysplasia and patellar tilt. The widely used Dejour classification was unreliable even after consensus training.
Conclusions: This study found that interrater reliability of many published PFI parameters, was unacceptably low. Unreliability may persist for those measurements with a high level of difficulty or ambiguity, or for indices that are infrequently assessed. Only reliable measurements should be used in clinical practice and research studies.
Interrater reliability of first and second round assessments of clinically relevant patellofemoral instability parameters by two fellowship-trained muskoloskeletal radiologists.
First assessment
Second assessment
Reliability
Variables
N
ICC
N
ICC
Initially reliable
Reliable with training
Unreliable
Xray
Trochlea crossing sign
33
0.455
10
0.625
X
Trochlear bump
34
0.205
7
0.435
X
Double contour sign
34
0.38
10
-0.2
X
Caton Deschamps Index
47
0.644
-
-
X
Medial patella avulsion fracture
50
0.43
18
0.779
X
Lateral patellofemoral angle
44
0.768
-
-
X
Lateral patellofemoral tilt
50
0.256
18
0
X
Congruence angle
44
-0.133
18
0.768
X
Patellofemoral arthritis
50
0.111
18
-0.062
X
Kellgren-Lawrence: medial
50
0
-
-
X
Kellgren-Lawrence: lateral
50
0
-
-
X
Leg length inequality
35
0.092
17
0.925
X
Leg length difference
15
0.985
-
-
X
Mechanical axis: left
49
0.777
-
-
X
Mechanical axis: right
50
0.665
-
-
X
MRI
Effusion
46
0.866
-
-
X
Bone bruise
45
0.961
-
-
X
Location of MFPL injury
43
0.639
-
-
X
TT-TG distance
44
0.706
-
-
X
Trochlear bump
20
0.861
-
-
X
Trochlear dysplasia: Dejour classification
42
0.174
19
0.211
X
Sulcus angle
11
0.339
20
0.684
X
Patellar tilt
44
0.841
-
-
X
Patellar subluxation distance
44
0.552
19
0.561
X
Osteochondral fracture
42
0.322
19
-0.108
X
Cartilage injury
38
0.245
20
0.686
X
Trochlear depth
20
0.743
-
-
X
EP-49
Management of first-time patellar dislocation: A survey of PRISM members
Shital Parikh1, Matthew Veerkamp1, PRISM Patellofemoral RIG1
1Cincinnati Children’s Hospital Medical Center, Cincinnati, USA
Introduction and Objective: To develop consensus-based guidelines for management of first-time patellar dislocation in children and adolescents as there is lack of high-level evidence to guide appropriate treatment.
Materials and Methods: A 29 question, multiple-choice, case-based survey was developed by 20 members of the Patellofemoral Research Interest Group (RIG) of the Pediatric Research in Sports Medicine (PRISM) society. The survey consisted of questions related to demographic information of the respondents (5 questions), management of first-time patellar dislocation without an osteochondral fracture in a 12.5 yr old girl (17 questions), and management of first-time patellar dislocation with a 2cm osteochondral fracture (7 questions). The survey underwent 2 rounds of iterations by RIG members and the final survey was administered to PRISM members using RedCap. Consensus-based guidelines were generated when more than 66% of respondents chose the same answer. Areas of disagreement were noted when there was no consensus.
Results: Of 157 eligible members, 79 (50%) responded. Sixty-one were orthopaedic surgeons and 18 were primary sports medicine physicians. 11 consensus-based guidelines were generated based on survey responses. For initial imaging studies, there was an increasing trend for obtaining MRI. Several components of non-operative treatment of first-time patellar dislocation such as brace, crutches, physical therapy and return to sports were better defined. Areas of discordance were noted if patient continued to have symptoms after initial conservative treatment and for management of contralateral first-time dislocation. In presence of an osteochondral fracture, surgical treatment (internal fixation of osteochondral fracture and simultaneous patellar stabilization) was agreed upon in principle but specific components (method of fixation, method of stabilization) were identified as areas of discordance.
Conclusions: Consensus-based guidelines offer recommendations for management of first-time patellar dislocation and would allow for standardization of care. Several changing trends and areas of disagreement were noted in clinical practice.
EP-50
Demographic and clinical characteristics of patellar instability patients from prospective JUPITER (Justifying Patellar Instability Treatment by Early Results) cohort
Meghan Bishop1, Jacqueline Brady2, Simone Gruber1, Matthew Veerkamp3, Joseph Nguyen1, Benton Heyworth4, Marc Tompkins5, Daniel Green1, Eric Wall3, JUPITER Study Group3, Beth Shubin Stein1, Shital Parikh3
1Hospital for Special Surgery Main Hospital, New York, USA, 2Oregon Health & Science University, Portland, USA, 3Cincinnati Children’s Hospital Medical Center, Cincinnati, USA, 4Boston Children’s Hospital, Boston, USA, 5TRIA Orthopedic Center Bloomington, Bloomington, USA
Objective: JUPITER (Justifying Patellar Instability Treatment by Early Results) is a hypothesis-driven, multi-armed, prospective cohort study to evaluate risk factors and predictors of clinical management and outcomes. Purpose of study is to provide objective analysis of patient demographics and characteristics and to determine clinical patterns for management of first-time and recurrent dislocators.
Methods: 21 surgeons from 12 institutions enrolled patients, 10-30 years of age. Radiographs and MRI were evaluated to confirm patellar dislocation and skeletal maturity. Patient demographics, clinical history, physical exam characteristics, and validated baseline patient reported outcome (PRO) scores were collected and analyzed. Conservative versus operative management was based on treating physician’s preference following standard of care guidelines. The cohort was divided between first-time vs recurrent dislocators and between conservative vs operative treatment.
Results: 1670 knees (62% female, age: 18.4 years, 334 (20%) skeletally immature) with patellar instability were enrolled. 58% of knees had recurrent dislocation. 35% of first-time dislocations were treated with operative management as compared to 86% with recurrent dislocations (p < 0.001). Of first-time dislocators undergoing operative management, 37% were due to presence of an osteochondral fracture. Patients with recurrent dislocations and those treated operatively were noted to have a higher prevalence of J-sign (p < 0.001) and patellar apprehension (p < 0.001) on both the affected and contralateral knee than first-time dislocators and patients treated non-operatively. Recurrent dislocators were nearly twice as likely to be ligamentously lax (Beighton score ≥5) as compared to first-time dislocators (p = 0.024). Baseline PROs demonstrated significant differences amongst groups, with recurrent dislocators having lower Pedi-FABS (p < 0.001) scores and higher Kujala (0.023), KOOS ADL (0.013), KOOS Sports (p < 0.001), and Pedi-IKDC (0.002) scores than first-time dislocators.
Conclusions: In a large cohort, operative management following first-time patellar dislocation was more common than previously reported. Recurrent dislocators had less deficits on scores related to daily activities, suggesting compensatory adaptive mechanisms
EP-51
Suicidal ideation in pediatric orthopedic patients
Whitney Herge1, Farzam Farahani1 2, Aaron Hurd1 2, Claire Shivers1, Shelby Cerza1, Sarah Parenti1, Anthony Riccio1
1Scottish Rite for Children, Dallas, USA, 2University of Texas Southwestern Medical Center, Dallas, USA
Introduction and Objective: Suicide is the second leading cause of death among American children aged 10 to 18 years, and those with physical health conditions have a 20% increase in suicidal ideation (SI) relative to their healthy peers. Despite this, suicidality in children with musculoskeletal problems is largely unstudied. The purpose of this study is therefore to determine the prevalence of SI in pediatric orthopaedic patients and identify risk factors for suicidality.
Materials and Methods: A retrospective review of all patients aged 10 years and older presenting for outpatient orthopaedic evaluation to a single pediatric institution over a 2-year period was conducted. Demographics, primary orthopaedic diagnosis, treatment history, pain symptomatology, and responses on the Ask Suicide Screening Questionnaire were compared between patients who endorsed suicidality and a matched cohort of patients without suicidal ideation.
Results: Of 6710 individual patient encounters, 163 children (2.4%) endorsed SI and 7/163 (4.3%) were experiencing imminent suicidal thoughts. Patients endorsing suicidality were predominantly female (73%), Caucasian (72%) with a mean age of 14.6 years. When compared to the matched cohort, children endorsing suicidality were significantly more likely to present with a chief complaint of pain (44.8% vs. 22.1%, p = 0.0005) and ultimately more likely to receive a non-structural, non-mechanical pain diagnosis (17 .2% vs. 5.5%, p = 0.0009). No other differences in ultimate diagnosis were identified between suicidal and non-suicidal patients with regard to general anatomic location (spine, hip, upper extremity, lower extremity) or specific diagnoses within these regions. Suicidal patients with pain did trend towards a higher likelihood of characterizing their pain as persistent or chronic (75.3% vs. 58.3%, p = 0.08).
Conclusions: This is the first study to assess SI in a large, outpatient, pediatric orthopaedic population. Suicidality is not uncommon among outpatient adolescent orthopaedic patients. White females with chronic pain complaints appear be at particularly high risk.
EP-52
Electromyography role in children with split cord malformation diagnosis
1Н. Turner National Medical Research Centre for Children’s Orthopedics and Trauma Surgery, Saint Petersburg, Russian federation
Introduction and Objective: Split cord malformations (SCM) are rare congenital abnormalities arising from a primary neurulation defect while embryological development of the spinal cord. SCM can cause progressive neurologic impairment and orthopedics disorders unless early properly identified and surgically treated.
Materials and Methods: We examined 27 children aged 8 months to 17 years with detected SCM (type I in 19, type II in 3, diplomyelia in 5 cases). With 2 patients, SCM was diagnosed prenatally, with 4 before 1 y.o., and with the others between 3 and 14 y.o. All children underwent orthopedical, neurological and electromyographical (EMG) examination with testing of sensory and motor fibers of the lower extremities (n.tibialis, n.peroneus, n.suralis, n.cutaneous femoris later.).
Results: Most patients had unilateral foot and lower leg shortening (60%), in 15% combined with progressive cavo-varus foot deformity on the side of shortening, in 26% - spinal deformity, in 14% - weakness in lower extremities and fatigue while walking. Skin signs in thoracic or lumbar spine projection were detected in 44% of children. Neurological examination has revealed mild distal monoparesis in 44%, lower paraparesis in 18%, sensory and trophic disorders of the affected limb in 6 children (22%) older than 10 years. According to EMG data, in 89% of cases no sensory nerve action potentials were found on the side of shortening lower limb and foot deformity (stimulating: all nerves). In 74% of cases there was a decrease of the amplitude of compound muscle action potentials from the foot by 34% (stimulating n. tibialis) and by 46% (stimulating n.peroneus).
Conclusions: Absence of sensory nerve action potentials from one lower limb is a quite frequent sign of SCM. In cases of the shortening lower limb, the EMG examination plays a very important role in early detection of congenital spinal cord pathology such as SCM.
EP-53
Validity of the Patient Reported Outcome Information System (PROMIS) in children and adolescents with lower extremity conditions
Nicholas Sullivan1, Patricia Miller1, Susan Mahan1, Samantha Spencer1, James Kasser1, Matthew Milewski1, Dennis Kramer1, Collin May1
1Orthopaedics, Boston Children’s Hospital, Boston, USA
Introduction and Objective: PROMIS has been utilized in orthopaedics to capture patient-centered indicators of health status but has not yet been validated in pediatric patients with lower extremity conditions. We aimed to evaluate the psychometric properties of PROMIS in this group.
Materials and Methods: We performed a prospective study of consecutive patients aged 11-17 years with lower extremity orthopaedic conditions treated at a single center. Children were enrolled into one of three arms of the study. Arm A assessed validity of PROMIS domains with corresponding subscales of the Pediatric Outcomes Data Collection Instrument (PODCI). Arm B assessed reliability by retesting patients from Arm A with the same PROMIS domains 2-4 weeks apart. Arm C assessed PROMIS domain responses pre-operatively and again at 6+ months post-operatively.
Results: Arm A (Validity): 259 subjects enrolled. Convergent validity was achieved between the PROMIS and PODCI mobility (r = 0.73; p < 0.001), upper extremity (r = 0.58; p < 0.001), PROMIS physical activity and PODCI sports and physical function (r = 0.57; p < 0.001), PROMIS depressive symptoms and PODCI happiness subscale (r = -0.55; p < 0.001) and the PROMIS pain and PODCI pain/comfort (r = -0.68; p < 0.001). Divergent validity criteria were met with correlation less than 0.30. Arm B (Reliability): 30 subjects were re-administered PROMIS domains 2-4 weeks apart (mean 22 days). Test/retest reliability was highest for the depressive symptoms (ICC = 0.72), mobility (ICC = 0.71) and pain (ICC = 0.65) domains. Arm C (Responsiveness): 88 patients completed PROMIS domains preoperatively and at a mean 11 months postoperatively. Largest effect sizes seen in pain (11.3-point improvement) and mobility (7.6-point improvement) domains.
Conclusions: PROMIS showed convergent and divergent validity with PODCI across all domains tested, high test/retest reliability for depressive symptoms, mobility, and pain, and significant responsiveness to changes secondary to surgery for lower extremity conditions.
EP-54
Using a digital inclinometer significantly improves the accuracy of derotation osteotomy: A simulation study
Anish Sanghrajka1, Daniel Watts1, Helen Chase1, Daniel Bye1
1Trauma & Orthopaedics, Norfolk & Norwich University Hospitals, Norwich, United Kingdom
Introduction and Objective: Derotation osteotomies are commonly performed in paediatric orthopaedic and practice. The purpose of this study was to determine whether the use of a digital inclinometer significantly improves the accuracy in attaining the desired correction.
Materials and Methods: We designed an electronic survey regarding derotation femoral osteotomy (DFO) including methods of intra-operative angular correction assessment and acceptable margins of error for correction. This was distributed to 28 paediatric orthopaedic surgeons in our region. A DFO model was created, using an anatomic sawbone with foam covering. 8 orthopaedic surgeons each performed two 30-degree DFOs, one using K-wires and visual estimation (VE), and the other using a Digital Inclinometer (DI). Two radiologists reported pre and post procedure rotational profile CT scans to assess the achieved rotational correction.
Results: There was a 68% response rate to the survey. The most popular methods of estimating intra-operative correction were reported to be K-wires and rotation marks on bone. The majority of respondents reported that a 6-10o margin of error was acceptable for a 30-degree derotation. This was therefore set as the upper limit for acceptable error margin in the simulation study. The mean error in rotation in the VE group of simulated DFO was 19.7 degrees, with error > 5 degrees and error > 10 degrees in 7 (88%) and 6 (75%) cases respectively. Mean error in DI group was 3.1 degrees, with error > 5 degrees in 1 case (13%).
Conclusions: Our results show that the compared to conventional techniques, the use of an inclinometer significantly improves the accuracy of femoral de-rotation and significantly reduces the incidence of unacceptable errors in correction. This is particularly important when smaller corrections of derotation are planned. We would suggest that digital inclinometers be used to assess intra-operative correction during derotation osteotomies.
EP-55
Double calcaneal osteotomy in correction of severe planovalgus foot deformity in ambulatory children with spastic cerebral palsy.A prospective case series study
Ahmad Saeed Aly1, Shady Abdelghaffar1
1Orthopedic, Ain Shams University, Cairo, Egypt
Introduction and Objective: Foot deformities are common in children with cerebral palsy (CP). A planovalgus foot deformity is most likely a consequence of muscle imbalance and abnormal forces on a skeletally immature foot. Pain with weight bearing, ulcerative lesions because of prominent talar head, and gait disturbances resulting from irreducible talo-navicular joint sublaxation are frequently occurred. Our hypothesis was to add medial slide calcaneal osteotomy to the lateral column lengthening, double calcaneal osteotomy (DCO), in order to correct more severe flexible planovalgus feet deformities and to decrease the risk of recurrence.
Materials and Methods: 16 patients with 24 symptomatic planovalgus feet in Spastic diplegic CP (or mixed with predominant spasticity) were treated by DCO. Nine patients in this study were males and seven were females. The mean age of the patients at the time of surgery was 10.74 years (range: 6 - 16 years). The mean follow-up period was 33.5 months (range: 24-48 months). All patients were ambulatory (GMFCS I: one case = 6.25%, GMFCS II: three cases = 18.75%, and GMFCS III: 12 cases = 75%).
Results: There was a statistically significant improvement of the clinical heel valgus from preoperative mean of 34.45 (range: 20.75 - 47.38) to postoperative mean of 16.03 (range: 11.25 - 20). Radiologically, there were a statistically significant improvement of all parameters. the percentage of talar head uncoverage reduced from preoperative mean of 31.64% (range:16.6% - 66.6%) to postoperative mean of 8.32 % (range: 0% - 33.3%), Calcaneal pitch angle mean improved from -1.08 (range: -5 - 5) to 28.58 (range: 24 - 33), and Lateral TMT1 Improved from 33.91 (range: 17.67 - 47.14) to 17.73 postoperatively (range: 14.25 - 20).
Conclusions: There is a significant improvement in the clinical and radiological parameters in spastic CP patients with flexible planovalgus feet underwent double calcaneal osteotomy on the intermediate term follow up.
EP-56
Hip displacement in spinal muscular atrophy: The influence of genetic severity and functional level
Armagan Can Ulusaloglu1, Ali Asma1, Michael W. Shrader1, Mena Scavina1, William Mackenzie1, Amanda Erb1, Jason Howard1
1Nemours Children’s Hospital, Delaware, Wilmington, USA
Introduction and Objective: Hip displacement (HD; subluxation/dislocation) is common in spinal muscular atrophy (SMA), but neither genetic severity nor gross motor function level have been investigated as risk factors. Newer disease-modifying agents (DMA) have improved function and overall health in SMA, but their effects on the prevention of HD are unknown. The study objective was to determine risk factors for HD development in SMA.
Materials and Methods: Case-control. Children with SMA, at least 1 hip X-ray, and minimum 2-year follow-up, were included. Primary outcome was prevalence of HD [migration percentage (MP) ≥ 40%]. Secondary outcomes included: SMA Type (I/II/III), SMN2 copy number, Hammersmith Functional Motor Scale (HFMS, out of 66), ambulatory status [Functional Mobility Scale at 50m (FMS50)], clinically-relevant scoliosis (> 40° and/or surgery), DMA use (> 1y duration, Nusinersen/Risdiplam/Onosemnogene abeparvovec), and mechanical ventilation, as risk factors. Univariate/multivariate logistic regression were performed to identify independent risk factors.
Results: Eighty-two patients (52% female) with SMA Type I (N = 32.39%), II (N = 36.44%), and III (N = 14.17%), met the inclusion criteria; with a final follow-up of 4.5 (SD:2.7) years. The prevalence of HD was 74%, with a mean age of HD onset of 4.6 (SD:2.7) years. HFMS > 35 was protective against HD by ROC analysis (AUC = 0.661, p = 0.02). Significant risk factors by univariate analysis were: SMA Type (I, p = 0.003; II, p < 0.001), DMA treatment (p = 0.03), non-ambulatory status (FMS50 = 1, p = 0.001), HFMS score (< 35, p = 0.01), and clinically relevant scoliosis (p = 0.03). Multivariate analysis revealed SMA Type II (p < 0.001), and < 3 SMN2 copies (p = 0.009) to be independent risk factors.
Conclusions: The development of HD in SMA is high, with risk factors associated with proxy measures of disease severity; most notably lower gross motor function level (by SMA type), and decreased number of SMN2 copies. Identified risk factors can be used in the development of surveillance programs for early detection of HD in SMA.
EP-57
The influence of baseline gait velocity on treatment results after single-event multilevel surgery in patients with cerebral palsy
Mauro César de Morais Filho1, Marcelo Fujino1, Francesco Blumetti1, Cátia Kawamura1, José Augusto Lopes1
1AACD, Gait Laboratory, São Paulo, Brazil
Introduction and Objective: The purpose of this study was to analyze the influence of baseline gait velocity on treatment results after single-event multilevel surgery (SEMLS) in a group of cerebral palsy (CP) patients.
Materials and Methods: 258 patients with spastic diplegic CP, GMFCS I-III, who underwent SEMLS and had done pre and post-operative gait analyses were included in the study. The influence of GMFCS and baseline gait velocity on Gait Deviation Index (GDI) change after surgical intervention was analyzed.
Results: The GDI changed from 51.3 to 58.4 after SEMLS (p < 0.001) in the studied group and the increase on GDI after SEMLS was greater (p = 0.003) in patients GMFCS I (10.6) and II (10.3) than GMFCS III (5.3). The standardized baseline gait velocity [velocity(cm/s)/lower limb length(cm)] was higher (p = 0. 019) in GMFCS I (1.46) than GMFCS II (1.25) and lower in GMFCS III (0.76) than GMFCS I and II (p < 0.001). Patients GMFCS III with standardized baseline gait velocity (SBGV) of 1.0 or more had a GDI increase of 7.8 after SEMLS while in those with SBGV < 1.0 the GDI improvement was 4.8 (p = 0.124). Finally, patients with reduction on GDI after the intervention had lower pre-operative gait velocity than subjects with improvement > 10 points (p = 0. 01).
Conclusions: Higher baseline gait velocity and GMFCS levels I and II were related to better outcomes after SEMLS in the present study. In GMFCS III patients, the increase of baseline gait velocity didn’t change significantly the GDI improvement after intervention.
EP-58
Predictors of postoperative urinary retention after posterior spinal fusion for adolescent idiopathic scoliosis
Tommi Yrjälä1, Linda Helenius1, Markku Taittonen1, Hanna Oksanen1, Heli Keskinen1, Terhi Kolari2, Ilkka Helenius3
1Turku University Hospital, Turku, Finland, 2Turku University, Finland, 3Helsinki University Hospital, Helsinki, Finland
Introduction and Objective: To determine predictors for postoperative urinary retention in adolescents undergoing posterior spinal fusion for idiopathic scoliosis. Postoperative urinary retention affects almost every third adolescent after spinal fusion for idiopathic scoliosis. There are limited data regarding the risk factors of postoperative urinary retention in this patient group.
Materials and Methods: A retrospective study with prospectively collected urinary retention data from paediatric spine register with 159 consecutive patients (114 females, mean age 15.6 years, range 10-21 years) undergoing pedicle screw instrumentation for adolescent idiopathic scoliosis at a university hospital between May 2010 and April 2020. Postoperative urinary retention was defined as an inability to void after catheter removal and documented residual over 300 mL as confirmed using an ultrasound or by catheterization.
Results: Postoperative urinary retention was diagnosed in 33% (53 of 159) of the patients during hospital stay. Opioid amount on the day of catheter removal (OR 6.74 [95% CI: 2.47, 18.36], p < 0.001), male gender (OR 2.26 [95% CI: 1.01, 5.05], p = 0.048), and increasing weight (OR 1.04 [95% CI: 1.01, 1.07], p = 0.014) were associated with postoperative urinary retention. Mean opioid consumption on the day of catheter removal was 0.81 mg/kg (95% CI: 0.66, 0.96) in the retention group vs 0.57 mg/kg (95% CI: 0.51, 0.64) in the non-retention group, p < 0.001.
Conclusions: Higher total opioid consumption, opioid amount on the day of catheter removal, higher weight, and male gender increases the risk of postoperative urinary retention in adolescents with idiopathic scoliosis undergoing posterior spinal fusion.
EP-59
Treatment of recurrent patellar dislocation in children and adolescents with medial patellofemoral ligament reconstruction - pediatric technique
João Cabral1, Ines Balacó1, Marcos Carvalho1, Oliana Madeira Tarquini1, Pedro Sá Cardoso1, Tah Ling1, Cristina Alves1
1Department of Pediatric Orthopaedics, Hospital Pediátrico - CHUC, EPE, Coimbra, Portugal
Introduction and Objective: Patellar instability is a complex disorder of the knee extensor mechanism, being one of the main knee problems that affect pediatric patients. Individually tailored surgical treatment is recommended for patients with recurrent patellar dislocations and usually involves specific paediatric techniques for medial patello-femoral ligament (MPFL) reconstruction. It is our objective to evaluate the results for the treatment of recurrent patellar dislocation in pediatric patients with na MPFL arthroscopic-assisted reconstruction, modified Chassaing technique.
Materials and Methods: We conducted a prospective study, with consecutive patients treated for recurrent patellar dislocation in our institution, period 2015-2018. We included patients with more than 1 episode of patellar dislocation, Caton-Deschamps index < 1.3 and TT-GT index < 20 mm. The surgical technique consisted of arthroscopic lateral patellar retinacular release, MPFL reconstruction with autologous gracilis, femoral soft tissue anchorage in the region of MPFL origin and patellar subperiosteal anchorage, followed by an Insall-like vastus medialis advancement. Pre and postoperative assessment was performed using the Lysholm functional scale, the apprehension test and patient’s satisfaction.
Results: There were 16 patients (9 girls, 7 boys), with 17 operated knees. Median age was 15.5 years (9-18) and median follow-up 19.5 months (7-29). The apprehension test was present in 76.4% of patients pre-operatively and 5.9% post-operatively (p < 0.001). Median Lysholm score went from 71.5 (33-89) preoperatively to 90.5 (75-100) post-operatively (p < 0.001). Satisfaction with treatment outcome was 88.2%. There were no recurrences.
Conclusions: In individuals with immature skeleton, procedures to treat patellar instability must not disturb growth. This arthroscopic-assisted modified Chassaing technique is minimally invasive, avoids possible physeal injuries and is effective and safe in children and adolescents, yielding good functional outcomes.
EP-60
First report and analysis of anterior inferior iliac spine avulsion re-fracture of the hip
Javier Besomi1,2,3, Jose Tomas Bravo2, Cristian Olmedo1, Jorge Joannon2, Daniela Landea4, Pedro Salgado4
1Pediatric Orthopaedic Surgery, Clinica Alemana de Santiago, Santiago, Chile, 2Facultad de Medicina Clinica Alemana - Universidad del Desarrollo, Santiago, Chile, 3Pediatric Orthopaedic Surgery, Hospital Clinico San Borja Arriaran, Santiago, Chile, 4Physiotherapy and Rehabilitation, Clinica Alemana de Santiago, Santiago, Chile
Introduction and Objective: Avulsive fractures of the anterior inferior iliac spine (AIIS) occur in adolescence, associated with indirect sports injuries. Re-fracture is a complication that has been described but there is no data on its prevalence or risk factors. The objective of this study is to describe the prevalence of hip AIIS re-fracture, identify risk factors for its occurrence, and describe its results.
Materials and Methods: Retrospective descriptive study of a case-series of patients with avulsion fracture of AIIS treated conservatively between the years 2016 and 2021. Re-fractures were registered at follow-ups. The age at time of fracture and re-fracture, latency from the first injury, radiological characteristics, and medical authorization to carry out sports activities were recorded. Functional results were evaluated using HOS score with sports subscale (HOSS).
Results: Thirty-four cases of avulsive fracture of the AIIS were obtained with a mean age of 13.7 years (11-16). With an average follow-up of 33 months (1.9-104), 6 cases presented acute re-fracture of AIIS, representing a prevalence of 17.6%. Re-fractures occurred at 12.8 weeks (6-22), with an average age of 13.3 years (11-15), all in male patients. All cases were managed conservatively. With an average follow-up of 21.4 weeks (1.4-38.6), there were no cases of nonunion, obtaining HOS score of 71.8 (57-76) and HOSS of 32.5 (27 - 36). Four patients returned to sport in an average time of 33.8 weeks (26 - 43.4). One case required arthroscopic labral repair surgery for persistent pain.
Conclusions: We present the first report in literature on the prevalence of avulsive re-fracture of AIIS. We obtained 17% re-fracture. In most cases, re-fracture occurred from kicking soccer ball prior to discharge without medical authorization for sports reintegration. We recommend not authorizing full sports reintegration before 12 weeks due to the risk of re-fracture.
EP-61
Walking hip spicas for paediatric femoral shaft fractures: Improving outcomes & reducing caregiver burden
Ben Steward1, Helen Gille1, Pranai Buddhdev1
1Broomfield Hospital, Broomfield, United Kingdom
Introduction and Objective: Walking, single-legged hip spicas have been shown to be safe and effective in young children with low-energy fractures. Despite its increasing adoption in North America, hospitals in Europe continue to utilise the traditional double-legged spica casts which preclude weightbearing. Our aim was to review our institution’s results to highlight the improved outcomes and help increase its acceptance for children aged 1 to 6 years in the UK/Europe.
Materials and Methods: A single-centre trauma database review of was performed to identify children aged 1-6 years presenting with femoral shaft fractures requiring hip spica application between 2011-2021. Patients admitted between 2011-2018 patients were treated with a traditional spica cast, with those from 2019 treated with a single-legged walking-hip spica. Demographic data, injury mechanism, hospitalisation analytics, time to weight-bearing and time in cast were collected by chart review. Final outcome was evaluated using Flynn’s criteria.
Results: Twenty patients presented with a low-energy fracture over the study period; 8 patients were treated with traditional hip spica cast, with twelve patients treated with a walking hip spica. The two cohorts were similar with regards to age, gender, mechanism of injury, number of hospital visits/radiographs and time in cast (mean 36 days, p = 0.3). Three children (25%) with walking hip spica casts required wedge adjustment to treat fracture malalignment. All patients with walking-hip spica cast were able to walk in the cast, with a mean time to weightbearing of 23 days (range: 15-51 days), compared to 71 days for those treated with traditional hip spica casting (p < 0.001). Flynn’s Criteria was found to be excellent in all patients.
Conclusions: Single-legged walking hip spicas facilitate earlier weight-bearing when compared to traditional spica casts, enabling accelerated mobility with reduced caregiver burden and requirement for wheelchairs. We hope to encourage and amplify its widespread adoption in the UK/Europe.
EP-62
Fully displaced pediatric supracondylar humerus fractures: Which ones need to go at night?
Susan Mahan1, Patricia Miller1, Jiwoo Park1, Nicholas Sullivan1, Carley Vuillermin1
1Boston Children’s Hospital, Boston, USA
Introduction and Objective: Determining which fully displaced supracondylar humerus fractures (SCHFx) are safe to postpone surgical treatment until daylight hours and which benefit from surgery overnight is challenging. The purpose of this study was to determine patient and fracture characteristics can provide guidance to optimal timing of displaced SCHFx that present overnight.
Materials and Methods: 225 completely displaced Gartland extension type 3 or 4 SCHFx in healthy patients that presented between 1800 and 0700 were identified. Demographic data, clinical information, radiographic assessment, and complications were collected retrospectively. Data analysis included univariate, multivariate logistic regression and classification and regression tree (CART) analysis was done.
Results: 225 SCHFx that presented to the ED between 1800 and 700 were included. 35% (78/225) underwent surgical treatment at night while 65% (147/225) were treated the next day. Overall complication rate was 6%; no difference based on timing of surgery. 12% (28/225) presented with a motor nerve injury while 6% (14/225) presented with a “pink pulseless” extremity. The most reliable radiographic predictor was the Maximum Displacement on the Anterior Posterior or Lateral view (MAPL). CART analysis was undertaken to develop a clinical algorithm to minimize complications: patients with a “pink pulseless” extremity or motor nerve injury were recommended for surgery overnight, while those with MAPL < 15 mm were recommended for surgery the next day.
Conclusions: This study has provided guidance on the timing of treatment for fully displaced pediatric supracondylar humerus fractures that present overnight. We provide a simple algorithm with three key clinical predictors for timing of treatment: presence of a “pink pulseless” arm, presence of a motor nerve injury, and displacement of any cortex by at least 15mm (MAPL). This provides a step forward to help practitioners who care for these difficult injuries make safer evidenced based decisions for their patients.
EP-63
Firearm-associated orthopedic injuries in the pediatric population of New York State (2016-2020)
Cordelia Carter1, Charles Lin1, Utkarsh Anil1
1NYU Langone Orthopedic Center, Department of Orthopedic Surgery, New York, USA
Introduction and Objective: Historically, gunshot wounds (GSWs) were a leading cause of injury/death among < 21 years of age in the USA. The COVID-19 pandemic resulted in a unique set of economic and social stressors, with the potential for gun-related violence increases. This study’s purpose was to identify/characterize firearm-associated pediatric orthopedic injuries in New York State (NYS) and differences in the injury rates before/after the COVID-19 pandemic.
Materials and Methods: Patients < 21 years old with firearm-related injuries between 1/1/2016 and 12/31/2020 were identified using the NYS Planning and Research Cooperative System (SPARCS) inpatient database. Diagnosis codes were cross-referenced with a comprehensive list of orthopedic fracture ICD-10 codes to identify pediatric patients with firearm-associated orthopedic injuries. Demographic information was collected. NYS census population estimates were used to calculate an annual firearm-related musculoskeletal injuries rate per million persons < 21 years. Poisson regression analysis compared the rate of orthopedic GSWs in 2020 to prior years, significance set at p < 0.05.
Results: 548 pediatric patients were admitted for firearm-related musculoskeletal injuries. The average patient age was 19 ± 2 years; 94% male, 73% Black, 17% Other, 9% White, 1% Asian and < 1% Pacific Islander. 49% had public insurance, 47% had private managed care, with the remainder self-paying or other. The majority of injuries occurred in large metropolitan areas. The average rate of firearm-related orthopedic injury was 5.6/1,000,000 persons < 21 years, with an average of 4.6/1,000,000 in the years 2017, 2018, 2019 and a high of 7.8/1,000,000 in 2020 (p < 0.001, Figure).
Conclusions: These injuries disproportionately affect Black males in urban areas. Pediatric orthopedic fractures rates secondary to GSWs declined in 2016-2019. This rate increased significantly in 2020, coinciding with the onset of the COVID-19 pandemic and the aforementioned stressors. Renewed prevention efforts are needed to avoid a parallel epidemic of pediatric orthopedic firearm injuries.
EP-64
Global variations in the management of diaphyseal forearm fractures in children: A survey of EPOS and POSNA members
Ludger Tüshaus1, Christoph Roeder2, Annelie Martina Weinberg3, Louise Klingenberg4, Sven-Oliver Dietz5, Nicolas Lutz6, Federico Canavese7, Cristina Alves8
1Department of Pediatric Surgery, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany, 2Landesklinikum Mödling, Mödling, Austria, 3Department of Orthopedics and Trauma, Medical University of Graz, Graz, Austria, 4Department of Orthopedics, Hvidovre Hospital, Hvidovre, Denmark, 5Department of Orthopedics and Trauma, Universitätsmedizin Mainz, Mainz, Germany, 6Service de Chirurgie de l’Enfant et de l’Adolescent, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, 7Department of Pediatric Orthopedic Surgery, Jeanne de Flandre Hospital, Lille, France, 8Department of Pediatric Orthopaedics, Hospital Pediátrico, Coimbra, Portugal
Introduction and Objective: Forearm fractures are among the most frequent fractures in children and adolescents. Treatment options are heterogeneous, and vary depending on fracture location, severity of displacement, patients’ age and surgeon’s preference. Traditional guidelines for nonsurgical treatment have been challenged in favor of surgical intervention, but it is unclear if this results in improved outcomes. It is conceivable that these differences represent our knowledge gaps about pediatric diaphyseal forearm fractures and may stimulate the development of large-scale prospective studies. A better understanding of the respective indication could help to set clinical standards and guidelines.
Materials and Methods: An electronic questionnaire to survey all EPOS and POSNA members has been created by European pediatric orthopaedic and trauma surgeons. Iteratively, questions were reviewed, selected, and optimized. A pilot test was conducted to test the survey and to establish content validity. The research was approved by the institutional review board of University of Lübeck. The survey was administered from October to November 2021.
Results: Variations and differences in the management of pediatric forearm fractures with respect to type of treatment, surgical indications, follow-up regimens and implant removal could be detected and mapped.
Conclusions: This large-scale survey is to our knowledge the first study assessing pediatric orthopaedic surgeons’ practices on pediatric diaphyseal forearm fracture management. Our results will help to understand current trends, similarities and differences across different regions.
Poisson regression for orthopedics GSWs, comparing 2020 to the years prior.
IRR = incidence rate ratio; CI = confidence interval.
EP-65
Construct validity of a novel simulator for pinning of supracondylar humeral fractures
Jan Duedal Rölfing1,2,3, Steven Long4, Ahmed A. Abood1,3, Emily Connor4, Emily Wagstrom5, Geb Thomas6, Don Anderson4, Heather Kowalski4
1Danish Paediatric Orthopaedic Research (dpor.dk), Denmark, 2Children’s Orthopaedics and Reconstruction, Aarhus University Hospital, Aarhus, Denmark, 3Corporate HR, MidtSim, Central Denmark Region, Denmark, 4Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, USA, 5Hennepin County Medical Center, Minneapolis, USA, 6Department of Industrial and Systems Engineering, University of Iowa, Iowa City, USA
Introduction and Objective: Dislocated supracondylar humerus fractures (SCH) in children are often treated by diverging Kirschner wires across the fracture to provide stable fixation. Building on a validated simulator for hip fractures, we developed an augmented reality simulator to train orthopedic residents in pinning SCH. The objective of this study was to assess the construct validity of the SCH simulator ie. its ability to distinguish surgical expertise.
Materials and Methods: 43 surgeons from the University of Iowa, University of Minnesota, and University of Aarhus, Denmark were included. 21 novices (first- or second-year residents), 11 intermediate surgeons (third- or fourth-year residents), and 11 advanced surgeons (fifth-year residents or faculty) participated. Surgical performance was graded on wire divergence, use of fluoroscopy, and overall time. Differentiating features of the simulator include: 1) camera-based tracking of a wire replaces fluoroscopic radiation exposure and 2) a plastic Sawbone replicates the feel of drilling through actual bone. After a warm-up exercise, participants were exposed to a reduced SCH and asked to place 3 diverging lateral wires based on haptic and radiological feedback by the simulator.
Results: Advanced and intermediate surgeons achieved significantly greater pin spread than the novice group (advanced 49%, intermediate 40%, novice 29%). The advanced group used significantly less fluoroscopy than the intermediate and novice groups (advanced 27 ± 6 images, intermediate 41 ± 17, and novice 52 ± 18). The advanced participants required significantly less time to place the 3-wire construct (advanced 321 ± 74 seconds, intermediate 448 ± 137, novice 592 ± 196). All results were statistically significant, p < 0.05.
Conclusions: Treating SCH is a critical skill that orthopedic surgeons must acquire. This study shows that the novel simulator can clearly distinguish between the 3 groups: novice, intermediate, and advanced performance. Future studies will investigate how simulator training can improve the surgical skill of novice and intermediate residents.
EP-66
Two-fold risk of fractures among children whose mother smoked during the pregnancy
Roope Parviainen1, Juha-Jaakko Sinikumpu1
1University of Oulu, Faculty of Medicine, Finland
Introduction and Objective: The possible early risk factors of the childhood bone fractures during gestation are not well known. Given that the tobacco may affect the development of the bone tissue, we researched the potential association of maternal smoking during pregnancy with childhood bone fractures.
Materials and Methods: A comprehensive birth-cohort research in Northern Finland was performed and all eligible children with the expected date of delivery in 1986 (N = 6718) were included. The maternal smoking during pregnancy was inquired with structured questionnaire one week before or after the birth. The main outcome was the fracture in childhood. Hobbies and other individual characteristics were thought to affect the fracture risk more in older children. Only children under school age (< 7 years) with in-hospital treated fractures were included. The inclusive fracture data was gathered from the National Hospital Discharge Register (NHDR). Altogether 86 persons had suffered from a fracture: 30 girls and 56 boys. Two of the children had suffered from two fractures. The association between the maternal smoking during pregnancy and the fractures were analysed by Poisson regression analysis. Sex, maternal age during childbirth, the socioeconomic status of the family, body-mass-index of the children (at seven years of age), asthma and childhood rheumatism were taken as confounders.
Results: Maternal smoking during pregnancy associated with 1.83-fold increase in the fracture risk when adjusted with the confounders (95% CI 1.06-3.02, p = 0.02).
Conclusions: Maternal smoking during pregnancy may be an independent risk factor for bone fracture in childhood. Closer basic studies are needed to describe the biological pathways between the fetal exposure to smoke and susceptibility to fractures.
EP-67
Clinical outcome of supracondylar humerus fractures in patients younger than 30 months
Ahmet Hamdi Akgülle1, Bulent Erol1, Yavuz Şahbat1, Hayati Kart1, Özgür BAysal1
1Marmara University Research and Education Hospital, Turkey
Introduction and Objective: There are many studies from diagnosis to treatment of supracondylar humerus fractures in the literature; however it is rarely seen in the younger age group, few studies examine the radiologic and functional results of this age group which have quite different characteristics. Our study aims to present midterm radiological and functional results in the pediatric population under 30 months old, who were operated in our clinic.
Materials and Methods: Retrospective analysis of data about patients younger than 30 months old, operated in our clinic between 2012-2020 for supracondylar humerus fractures with at least 1 year follow-up.
Results: Fifty-two patients were available in the study, with patient characteristics, surgical, early postoperative data, midterm functional, and radiologic evaluation. Flynn outcome scores and variant HSS scores of these patients were compared with previous data. Similar clinical outcomes were achieved in this age group, compared to previously reported results of older patient groups.
Conclusions: Using a medial pin to achieve and protect stability in this age group overweights the risk of iatrogenic ulnar nerve damage. Patients with flexion-type fractures or who had additional surgery because of different injuries had more LOR and worse outcome. Younger patients tend to have more varus malalignment but similar functional results. High-energy fractures have different characteristics, and a unique approach for this kind of trauma may be needed.
EP-69
Surgical exploration of the pink pulseless supracondylar fracture
Philip McKeag1, Hean Wu Kang1, Richard Napier1
1Royal Belfast Hospital for Sick Children, United Kingdom
Introduction and Objective: Controversy exists with regards to the management of the pink pulseless supracondylar fracture. The British Orthopaedic Association Standards for Trauma (BOAST) Guidelines recommend observation for a pulseless limb following manipulation under anaesthetic and Kirschner wire fixation for supracondylar fractures provided that there are signs of perfusion. Numerous studies exist in the literature recommending both observation and surgical exploration for these injuries. An observational study was carried out in The Royal Victoria Hospital For Sick Children looking at patients undergoing surgical exploration for pink pulseless supracondylar fractures to determine the intraoperative findings.
Materials and Methods: Patients undergoing surgical exploration for pink pulseless supracondylar fractures were identified between the 27th of April 2008 and the 29th of September 2019 using Theatre Management System. Theatre operation notes and medical chart records were reviewed for each patient.
Results: 13 patients were identified. 6 patients were female and the average age was 5.3 years. Each patient sustained a Gartland Grade 3 supracondylar fracture. Following open exploration, 15% of patients were found to have the brachial artery and median nerve caught in the fracture site. 38% of patients sustained an injury to the brachial artery with 1 patient sustaining a transection of the artery. 15% of patients were found to have superficial tethering of the brachial artery in the fracture site. 23% of patients sustained a nerve injury, all of which recovered with observation.
Conclusions: Surgical exploration was justified given the intraoperative findings. 100% of patients had some form of brachial artery compromise on exploration.
EP-70
Treatment of unicameral bone cysts: A comparative study during 8-year period
Bojan Bukva1, Sinisa Ducic1, Mikan Lazovic1, Filip Milanovic1
1Pediatric Orthopedics and Traumatology, University Children`s Hospital, Belgrade, Serbia
Introduction and Objective: Unicameral bone cysts (UBC) are benign bone tumor-like lesions. The etiology of UBC is still unclear. There is no consensus about the protocol of UBC treatment. The aim of this study was to evaluate the effectiveness of three different techniques for the treatment of UBC.
Materials and Methods: This study included 129 pediatric patients with UBC treated during the 8-year period. The mean follow up was 7.14 years. The following parameters were observed: gender, age, site, length of cyst, cyst index, cortical thickness, presentation of pathologic fracture, healing of cyst, treatment complications and length of hospitalization. These parameters were correlated to three treatment modalities, i.e. intracystic methylprednisolone acetate (MPA) injection (group 1), curettage with bone grafting (group 2) and osteoinductive procedure using demineralized bone matrix [(DBM) (group 3)].
Results: According to the method of treatment, statistical significance was found for the site of affection, length of the cyst, presentation of pathologic fracture before treatment initiation and complication rate. Also, we found statistically significant differences in cyst healing and length of hospital stay between the intracystic MPA injection group and curettage and autologous bone grafting group. The same variables yielded significant differences between the curettage and autologous bone grafting group and osteoinductive procedure using DBM group. Statistically significant correlation between healing of the cyst and length of hospital stay according to treatment options was found. The length of hospital stay was shortest in patients treated by MPA injection into the cyst, while the period of cyst healing was shortest in patients treated by osteoinductive procedure.
Conclusions: Complete healing of UBC can be achieved only using open surgery procedure. Intracystic methylprednisolone acetate instillation can be considered a good option for initial treatment of UBC.
EP-71
Percutaneous alcohol-based sclerotherapy in aneurysmal bone cyst in children and adolescents. A retrospective study of 41 patients
Maria Tirta1, Georgia Antoniou1, Anastasia Pilichou1, Panagiotis Krallis1, Maria Stefanou1, John Anastasopoulos1
12nd Department of Pediatric Orthopaedics, Agia Sofia Children’s Hospital, Athens, Greece
Introduction and Objective: Aneurysmal bone cyst (ABC) is a benign bone lesion of childhood and adolescence, the management of which is controversial. The aim of this study was to analyze the outcomes of treatment in a series of patients with a primary ABC who had been treated by percutaneous sclerosant therapy using absolute alcohol (ethanol 96%).
Materials and Methods: We retrospectively reviewed the medical records of all the pediatric patients with ABC that were hospitalized in our Pediatric Orthopeadic Clinic and had a follow-up of at least 6-months, from January 2014 to September 2021.
Results: Forty-one children with ABC were included in our study, 33 males (80.5%) and 8 females (19.5%). The most frequent location of the lesion was the humerus (17 cases) followed by proximal femur and fibula. Revelation was mainly with pain (51.2%) and bone fracture (36.6%). All ABCs were treated with sclerotherapy, which was successful in 30 patients with a single session (73.2%). The mean age at first sclerotherapy was 9.92 years old (SD: ±3.56). Two sessions were needed in 10 patients (24.3%) and three sessions for only one patient. All ABC’s had bloody content and none of them was classifies as lymphatic. There was no recurrence, at a minimum 6-months follow-up. Considering the complications, one patient had a peroneal nerve paresis in the first session, and one had a local skin irritation.
Conclusions: Its clinical and radiological efficacy makes sclerotherapy an alternative primary treatment choice in ABC, avoiding recourse to invasive surgery.
EP-72
The proximal congenital radioulnar synostosis: Quality of life of paediatric patients. A multicentre study
Paola Zarantonello1, Giovanni Luigi Di Gennaro1, Sebastian Farr2, Giovanni Trisolino1, Diego Antonioli1, Giovanni Gallone1, Stefano Stallone1
1Rizzoli Orthopedic Institute, Bologna, Italy, 2Speising, Vienna, Austria
Introduction and Objective: Congenital radioulnar synostosis (CRUS) is a rare upper limb abnormality characterized by a prevalent fixed forearm attitude usually in pronation. The study aims to analyse patients with CRUS treated in the last 10 years in two different reference centers for pediatric orthopaedics.
Materials and Methods: We retrospectively collected all data reporting: demographic data, syndromes and associated symptoms, position and articulatity of the affected limb, type of treatment. Radiographs were evaluated to classify synostosis according to the Cleary-Omer classification. Complications were collected in accordance with the Clavien-Dindo-Sink classification. Patients were contacted to administer them the Quickdash and MEP scores.
Results: 70 patients (25 females, 45 males) for 93 forearms (38 right, 50 left, 5 not detected) were assessed. Average age at the first evaluation was 4.9 years. Mostly, the forearm was fixed in pronation (only 2 were in supination), particularly between the neutral position and the minimum pronation (0-20°). 37 cases were surgically treated with proximal derotative osteotomy and eventually the ulnar neurolysis (19). 2 cases were subjected to resection of the synostosic bridge. 5 complications were reported in 5 patients. The average age at follow-up was 9.5 years. At post-operative evaluation, most patients (both operated and not) declared a forearm in a neutral position and a good degree of satisfaction with satisfactory quality of life (MEPS: 90.1, Quickdash: 18%).
Conclusions: The proximal derotative osteotomy for CRUS, even if not restore the mobility of the forearm, allows to place it in a more comfortable position, improving autonomy and quality of life, as demonstrated by the collected data. Complications are infrequent and mostly transient. There are no statistically significant differences between different hardwares or associated procedure.
EP-73
Corrective procedure for flexion contracture of the elbow in neonatal palsy sequelae: Long term follow-up
Filippo M Senes1, Anna Maria Nucci1, Annalisa Valore1, Nunzio Catena2
1Reconstructive Surgery and Hand Surgery Unit - IRCCS Istituto Giannina Gaslini, Genoa, Italy, 2Hand Surgery and Microsurgery Uniti - Pediatric Orthopedic and Traumatology Unit, AO SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
Introduction and Objective: Aim of this paper is to validate a procedure for correcting elbow flexion contracture in patients suffering from brachial plexus neonatal palsy sequelae during their teens. Elbow flexion contracture represents an unsolved problem in the natural history of obstetric brachial plexus palsy (OBPP) because of the consistent deformity recurrence. Following a previous paper, in which an original technique was proposed in a small sample of patients, the authors show the possible correction of the deformity in a larger group of patients.
Materials and Methods: The procedure includes a combination of a posterior approach to the elbow with olecranon tip section and an anterior one with capsulotomy and soft tissue release to improve elbow range of motion. A series of 26 patients, who underwent the procedure, were checked out in medium and long term. Collected data were age, type of brachial plexus palsy, length of hospitalization, duration of surgery, preoperative and postoperative elbow range of motion, preoperative and postoperative DASH scores and satisfaction scores. Explaining further details about the procedure, the Authors report their results, including a statistical analysis.
Results: At the final follow-up, the mean increase of elbow extension was about 22°. Functional outcomes were successful as well, with a mean increase of 10 points of DASH score. Over 75% of patients were fully satisfied with their outcome.
Conclusions: The outcome has confirmed the good efficacy of the procedure in increasing elbow extension but also in improving cosmetic appearance in adolescents suffering from flexed elbow in OBPP sequelae.
EP-74
The treatment outcome of pediatric trigger thumb: Open surgery versus nonoperative management according to age
Jung Yun Bae1, Ju Mi Hwang1
1Department of Orthopedic Surgery,Pusan National University Yangsan Hospital, Yangsan-si, South Korea
Introduction and Objective: Pediatric trigger thumb (PTT) is a condition of flexion deformity of the interphalangeal(IP) joint in children. There have been debates about the results of surgical treatment in older children, even though many studies showed excellent results in PTT. Although the surgical outcome is satisfactory, the indications for nonoperative treatment for this condition are not clear. The purpose of this study is to evaluate the treatment results according to the treatment methods and age, and present the criteria for when and what treatment should be performed.
Materials and Methods: Data on 166 thumbs in 137 children were collected prospectively. We divided patients according to treatment methods into surgery group and conservative treatment group and according to age into two groups (A: under 4 years, B: over 4 years). We investigated the presence or absence of IP joint flexion deformity, triggering and complications.
Results: In surgery group, 92% of group A and 96.5% of group B were experienced complete symptom relief but there was no statistical significance (p > 0.05). As a result of Kaplan-Meier survival analysis for the conservative treatment group, A1 group, under 4 years old, improved in 51.5%, and the average time to improvement was 23 months. A2 group improved in 54.5%, the average time required was 18.5 months, and there was no significant difference in the survival curve between the two groups (p > 0.05).
Conclusions: There was no significant difference in treatment results according to the age in the conservative treatment group. Also, there was no significant difference between the two surgical treatment groups. If there is no pain or discomfort and the patient does not have symptoms such as being shy about deformity, surgical treatment after performing conservative treatment for about 2 years even for the over 4 years old group should be taken into consideration.
EP-75
Temporary epiphysiodesis in adolescent patients with ulnocarpal impaction syndrome
Philipp Scheider1, Rudolf Ganger2, Sebastian Farr2
1Department of Orthopaedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria, 2Department of Pediatric Orthopaedics and Foot and Ankle Surgery, Orthopaedic Hospital Speising, Vienna, Austria
Introduction and Objective: Adolescents with ulnar positive variance can develop ulnocarpal symptoms due to ulnocarpal impaction syndrome. Common treatment methods are conservative therapy, distal ulna epiphysiodesis or eventually ulnar shortening osteotomy. The aim of this preliminary case series was to investigate a recently described, new therapeutic approach using a reversible, temporary epiphysiodesis technique, following the principles of guided growth.
Materials and Methods: Seven cases with the diagnosis of a painful ulnar positive variance, which underwent a temporary epiphysiodesis, were retrospectively evaluated. These cases consisted of four individual patients who received an intraoperatively customized plate fixation to slow down growth. The following parameters were collected: diagnosis, age at surgery, age at explantation, growth plate status at explantation, ulnar variance before and after surgery, complications and any clinical and radiological abnormalities. The radiological measurements of ulnar variance were performed according to the Gelbermann method.
Results: The seven investigated cases (average age at surgery 12.4 years; average age at explantation 14.7 years), in which a temporary epiphysiodesis was performed, showed an average ulnar variance of +3.9 mm (range: from +1.9 mm to +6.1 mm) before the start of therapy. After explantation, an average ulnar variance of +0.1 mm (range: from -3.2 mm to +5.0 mm) was observed, which corresponds to an average reduction/improvement of -3.8 mm (range: from -0.5 mm to -9.3 mm). The ulnocarpal wrist complaints were significantly reduced after the intervention. One case needed a secondary ulnar shortening osteotomy.
Conclusions: The described method of a temporary, reversible epiphysiodesis is an elegant, less invasive technique to correct the ulnar positive variance without irreversibly closing the growth plate. In case of therapy failure, a secondary ulna shortening osteotomy is still possible.
EP-76
Age-related outcomes and complications of osteodistraction in the pediatric upper extremity: A large retrospective single-center study of 61 cases
Philipp Scheider1, Rudolf Ganger2, Sebastian Farr2
1Department of Orthopaedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria, 2Department of Pediatric Orthopaedics and Foot and Ankle Surgery, Orthopaedic Hospital Speising, Vienna, Austria
Introduction and Objective: The study purpose was to assess (1) the complication rate of osteodistraction in the pediatric upper extremity, its severity and relation to patient-and treatment-specific parameters, and (2) dedicated patient-reported outcome scores after these procedures.
Materials and Methods: This retrospective study analyzed chart of patients undergoing osteodistraction of the upper limb between 2003 and 2020. Demographics, distraction-specific parameters, healing index, and any complications graded according to the Sink grading scale (grades 1-5) were extracted. An additional phone interview was performed to assess patient satisfaction and functionality of the elongated limb using the Quick-DASH score.
Results: This study included 61 cases from 48 individual patients. The mean age at the start of distraction was 11.5 ± 3.6 years. The ulna was the most frequently lengthened bone, with 21 (34.4%) cases. 94 complications were observed, with an average complication rate of 77.0%. Based on the Sink grading scale (1-5), grade 3 complications were most common (n = 29; 47.5%) followed by grade 1 (n = 14; 23.0%), 2 (n = 14; 23.0%) and 4 (n = 4; 6.6%). A significantly lower and thus better bone healing index was observed for the age category < 10 years compared to the 14-18 years group (p = .006). The average satisfaction was 4.2 ±1.0 points out of 5. The mean Quick-DASH score was 14.1 ± 12.5, indicating very good clinical outcomes.
Conclusions: Despite the occurrence of numerous complications, high patient satisfaction and good daily life functionality of the treated limb was observed. An age of >14 years at the beginning of therapy had a negative prognostic effect on bone healing during distraction. Thus, osteodistraction in the upper extremity may preferably be performed below 10 years of age because of enhanced bone regeneration.
EP-77
Testing a new method of osteosynthesis of antebrachium fractures in children; A prospective randomized controlled longitudinal study
Lærke Gyllenborg1, Christian Wong1, Ture Karbo2
1Department of Orthopaedics, Hvidovre University Hospital, Hvidovre, Denmark, Denmark, 2Department of Orthopaedic Surgery Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
Introduction and Objective: Children’s forearms fractures are commonly treated surgically with Kirschner Wires (KW) or Elastic Stable Intramedullary Nails (ESIN). The “Minimally Invasive Reduction Osteosynthesis System” (MIROS) seems technically adequate for the treatment of these fractures by combining benefits of external fixation and intramedullary nailing. Benefits are postulated to be minimally invasive, have short removal time, and unnecessariness of postoperative casting. We undertook a prospective randomized controlled longitudinal study of antebrachial fractures in children comparing treatment results of MIROS to KW and ESIN.
Materials and Methods: Twenty children were included consecutively and block-randomized to treatment with either conventional surgery (5KW/5ESIN) or MIROS (10). Radiographic alignment and clinical parameters of scar size, pain status, grip strength, physical activity, and range of motion after three months and after five years were measured and compared.
Results: All osteosynthesis methods had similar pain status, bilateral strength difference, duration of surgical insertion, and return to recreational activities at three months- and five years follow up. The MIROS had a significantly smaller scar size and faster removal time, and the need for postoperative casting was significantly less. All osteosynthesis systems maintained radiographically fracture reduction at three months and five years follow-up. Refractures occurred when operated on with MIROS, but the overall complication rate was non-significant.
Conclusions: In conclusion, MIROS is non-inferior to other surgical methods for forearm fractures in children. MIROS has the clinical benefit of omitting casting after surgery, obtaining reduced scar size, and shorter removal-time without full anaesthesia.
EP-78
Flexor tendon injuries in the pediatric age: What results can be expected?
Marcos Carvalho1, Ricardo Marques1, Pedro Sá Cardoso1, Tah Ling1, Ines Balacó1, Oliana Madeira Tarquini1, João Cabral1, Cristina Alves1
1Department of Pediatric Orthopaedics, Pediatric Hospital, CHUC, EPE, Coimbra, Portugal
Introduction and Objective: Flexor tendon injuries are rare in children, posing specific diagnostic and therapeutic challenges. This study aims to describe epidemiologic characteristics of flexor tendon injuries in children and evaluate the outcomes of surgical treatment.
Materials and Methods: Retrospective study of patients with acute traumatic flexor tendon injuries treated between 2012-2019. We analyzed demographics, lesion mechanism, surgical technique, clinical results, complications and secondary surgical procedures. Functional results were assessed through the Total Active Mobilization (TAM) score.
Results: Twenty patients included (n = 34 tendons), with median follow-up of 7 months [min-3; max-34] and median age at time of surgery of 13 years-old [min-1; max-17]. Male gender was predominant (n = 16). The most prevalent injury mechanism was a cut (n = 17), mostly affecting the 4th digit (n=10) and Verdan’s zone II (n = 13). Modified Kessler was the suture technique more commonly used (n=31) and polypropylene was the preferred suture material (n = 19). All patients were immobilized with splint for a median time of 4 weeks [min-1; max-7]. According to TAM, 15 patients reached a score > 75%, independently of age (p > 0.05). Stiffness was the main complication observed. Complications were identified in 37% of patients and were most common in those older than 10 years-old (p > 0.05) and zone II lesions (p > 0.05). Four patients (20%) needed a second surgical intervention.
Conclusions: Flexor tendon injuries in children are relatively uncommon and prevail in the male gender, similarly to the adult population. Principal complication observed was stiffness, more prevalent in children above 10 years-old, although without relevant functional implications, as surgical treatment enabled good or excellent outcomes in 75% of patients.
EP-79
Peripheral nerve injuries of the upper extremity in paediatric population: Long-term outcomes and prognostic factors
1Orthopaedic Surgery, Necker Hospital, Paris, France
Introduction and Objective: Peripheral nerve injuries of the upper limb are rare in children and poorly documented. The aim of this retrospective study was to analyze the long-term sensitive and motor results, and to determine predictor factors of recovery after such lesions surgically treated in children.
Materials and Methods: Thirteen children with a mean age at injury of 9.2 years were included. Sensory perception was measured with monofilaments and the static 2-point discrimination test. Grip and motor strength were collected. Cold intolerance, persistence of paresthesias or irritative syndrome in front of the wound were looked for. Quality of life was assessed by QuickDASH.
Results: The injury involved the radial (3), median (9), or combined median and ulnar (1) nerves repaired by primary direct suture (11) or autologous nerve graft (2). The mechanism was traumatic by glass (10) or road accident (3). The dominant limb was involved in 7 cases. After a mean follow-up of 7.8 years, touch sensitivity was normal (10) or slightly deficient (3) in the monofilament test. Discrimination test was normal (11) or adequate (2). Strength was complete in 10 patients. Three patients had cold intolerance, 4 had paraesthesia, 1 of them required medical treatment. An irritative syndrome in front of the wound was found in 3 patients. Mean QuickDASH was 5.6. There was no statistical difference in both sensory and motor postoperative recovery between partial and complete lesion, suture and nerve graft or according to the location of the injury. There was a better sensory recovery in children < 12 years (p < 0.05). The sensory prognosis was also better without associated lesions (p < 0.05).
Conclusions: Sensitive, motor and functional results after surgical treatment of peripheral nerve injuries of the upper limb were globally satisfactory in children. Sensory recovery was better at early age and without associated lesions.
EP-80
Signaling overuse sports injuries in the pediatric elbow: Physicians’ item collection
Brinne Roorda1, Christiaan van Bergen1, Denise Eygendaal1, Bertram The1, Iris van Oost1
1Amphia Hospital, Breda, The Netherlands
Introduction and Objective: Detection of overuse in pediatric athletes is often delayed resulting in injuries. Sports-related overuse injuries in children can be associated to functional limitation and even progressive joint degeneration in adulthood. Timely diagnosis is essential to prevent further damage. The aim of this study was to develop a measurement instrument for signals of overuse elbow injuries in young athletes in elbow loading sports. A valid instrument for early detection as such does not exist to date. Data were obtained on presence and severity of overuse injuries in pediatric patients from a focus group of physicians involved in the management of these injuries.
Materials and Methods: A group of thirteen (pediatric) orthopedic surgeons, sports physicians and physiotherapists, experienced in guidance and treatment of pediatric athletes in elbow-loading sports, participated in a focus group. Signals and functional limitations of pediatric athletes with overuse elbow injuries caused by sports activity, were discussed and rated in order of importance. The results were organized into subcategories.
Results: Twenty-two important signals and functional limitations were identified by the focus group. The participants agreed that the most important signal is pain. Additional important signals included the onset of the complaints and swelling of the joint. The most important functional limitations were decreased sports performance, restriction in movement and mobility both during sports and when at rest.
Conclusions: The results of this study form a comprehensive item set for identifying overuse elbow injuries in pediatric athletes. They can be used in the future for development of a measurement instrument of overuse injuries of the elbow. This instrument will be able to facilitate the detection of warning-signs and of pediatric athletes at risk for overuse elbow injuries in order to prevent serious overuse injuries in the future.
EP-81
Innovation of COVID-19 pandemic; A prospective study on paediatric forearm fractures manipulations in A&E department of a District General Hospital
Hafiz Umer1, Hafiz-Javaid Iqbal1, Matthew Nixon1, Mark Webb1, Peter Kenyon1, Sophie Dodd1
1Countess of Chester Hospital NHS Foundation Trust, United Kingdom
Introduction: Forearm fractures equate for up to 36% of all paediatric fractures. Majority of these can be managed conservatively in plaster cast. Performing reduction and cast application of these fractures in the Accident & Emergency (A&E) Department may benefit patient, parents and the hospital.
Method: We performed a prospective study on manipulations of angulated paediatric forearm fractures under sedation (MUS) using either Ketamine or multimodal analgesia (Intranasal diamorphine, Entonox). Visual analogue scores (VAS) and, Face, Leg, Activity, Cry, Consolability (FLACC) scores were used to evaluate pain and anxiety before, during and after the procedure. Satisfaction scores from parents and nursing staff were also recorded. A matched cohort of patients who underwent manipulation under anaesthesia (MUA) in theatres, were selected and outcomes including, complications and length of stay were compared.
Results: Analysis was performed using radiographs and medical documentation between February 2020 and February 2021. 21 patients underwent MUS and 21 patients had MUA in theatre. Both groups contained 11 diaphyseal and 10 metaphyseal fractures with an age range of 3-15 years. In MUS group, average pain score pre-procedure was 6/10 and post-procedure was 2/10. Average FLACC score during the procedure was 2 and average parent and staff satisfaction was 9/10. In the MUS group, only 1 patient required further (surgical) procedure versus 0 in the MUA group (p=1.0). Overall, in the MUS group, 3 complications occurred: a broken cast, pressure area and a loss of reduction compared to 3 complications in the MUA group: 2 cases of reduced range of motion requiring prolonged physiotherapy and one radio-ulnar impingement.
Conclusions: Manipulations of paediatric forearm fractures in A&E departments are safe, well-tolerated by patients and have comparable outcomes to manipulations performed in theatre with the added benefit of avoiding general anaesthesia, preventing need for admission for the patient and saving costs.
EP-82
Displaced midshaft clavicle fractures treated with orif vs non-op: Equivalent strength, endurance, and kinematics
Clare Kehoe1, Roger Widmann2, Nicolas Pascual-Leone2, David Scher2, Emily Dodwell2
1Johns Hopkins University School of Nursing, Baltimore, USA, 2Hospital for Special Surgery Main Hospital, New York, USA
Introduction and Objective: Treatment of displaced midshaft clavicle fractures in adolescents remains controversial. Previous motion analysis studies have suggested no significant difference in strength or endurance in patients aged 10-16 treated operatively vs non-operatively. The purpose of this study was to assess strength, endurance, and range of motion in older adolescents with mid-shaft clavicle fractures treated with anatomic reduction internal fixation vs those allowed to heal mal-united.
Materials and Methods: Patients aged 14-19 at time-of-injury with mid-shaft clavicle fractures shortened ≥15 mm were included whether treated operatively or non-operatively. An age and sex matched control group was included. Shoulder strength in flexion and extension was measured as an average peak force in Newton-meters, Shoulder endurance was measured using work fatigue and presented as a percent decrease from maximum force. Range of motion was tested with abduction and presented as a coefficient of variance between tested sides. Two samples t-tests were used to compare continuous variables. Statistical significance was set at p-value = 0.05. Analyses were completed with Stata, v14.2 (StataCorp, College Station, TX).
Results: Six operative, 10 non-operative, and 11 controls were included. The mean age at testing was 17.8 years, 16.8 years, and 17.8 for operative, non-operative, and controls, respectively. No significant difference in flexion or extension strength, endurance, or range of motion was noted between affect and non-affected cases (p = 0.23, 0.74, 0.97, 0.47) or dominant versus non-dominant arms (p = 0.77, 0.70, 0.93, 0.46).
Conclusions: No difference in shoulder strength, endurance, or motion was found between patients treated with ORIF, non-operative treatment or controls. These results build upon previous motion studies, demonstrating no functional deficit for fractures allowed to heal malunited in an older age cohort (14-19 years at time-of-injury), controlled for hand-dominance. For most adolescents with displaced mid-shaft clavicle fractures, non-operative management should be considered as first line treatment.
EP-84
Sprengel deformity - clinical and radiographic outcome following surgical intervention
Antfang Carina1, Andrea Laufer1, Georg Gosheger1, Anna Maria Rachbauer1, Gregor Toporowski1, Adrien Frommer1, Henning Tretow1, Robert Rödl1, Bjoern Vogt1
Introduction and Objective: Sprengel deformity is a rare skeletal deformity due to a maldescent of the scapula. In addition to aesthetical issues, the limitation in abduction of the affected shoulder is the primary indication for surgical intervention. The most widely used surgical procedures for lowering the scapula are the techniques according to Green and Woodward, releasing the shortened muscles proximate to the scapula and the spine, respectively.
Materials and Methods: We investigated patients with Sprengel deformity consulting our hospital from 2016 - 2021. 13 patients with 15 affected shoulders (right = 6; left = 5; bilateral = 2) were included in the study. The deformity was classified using the clinical (Cavendish) and radiographic (Rigault) classification systems. 7/13 patients had a severe deformity (Cavendish III/IV; Rigault III) and therefore received either surgery according to Green (n = 3) or Woodward (n = 4). Median age was 5 years (range 3-6) at date of surgery.
Results: At first consultation we identified the following grades of severity according to Cavendish I = 1, II = 5, III = 4, IV = 5 (average 2.9) and according to Rigault I = 3, II = 6, III = 6 (average 2.2). Of these patients 7 received surgery. Their preoperative average Cavendish as well as average Rigault grades (3.6 and 2.9 respectively) could postoperatively be improved to an average of 1.4. Associated deformities were found in 13 cases (Klippel-Feil-Syndrome=7, Os omovertebrale =8). Abduction in the affected shoulder was improved by 50° postoperatively. Complications were seen in two patients, one pneumothorax and one transient radial nerve palsy.
Conclusions: Both surgical techniques achieve satisfying results in correction of Sprengel deformity. Following surgery, the aesthetic aspect as well as the function show a considerable improvement. The main purpose for surgery should be the severity of deformity and the limitation in the abduction of the shoulder.
EP-85
Measurement for objective diagnosis of multidirectional instability of shoulder in adolescent patients
Mason Yoder1, Matthew Veerkamp1, Colin McDonald1, Shital Parikh1
1Cincinnati Children’s Hospital Medical Center, Cincinnati, USA
Introduction and Objective: To identify objective criteria for Multidirectional Instability (MDI) diagnosis in adolescent patients based on shoulder capsular dimensions on MR imaging
Materials and Methods: 24 adolescent patients surgically treated for MDI were age-matched to 25 control patients. On MR arthrogram, width and depth of rotator interval and multiple linear dimensions of glenohumeral capsule were measured on sagittal-oblique MR arthrography sequences, after controlling for glenoid size. These dimensions were compared between the 2 groups using Student’s t-test. ROC curves were generated to calculate threshold values for measured variables.
Results: 24 patients (28 shoulders), 20 females, 4 males were in MDI group; average age at time of surgery 15.2 years (range, 8-20 yrs). Control group of 25 patients (27 shoulders), 9 females, 16 males; average age 15.4 years (range, 11-18 yrs). The rotator interval depth was significantly greater in the MDI group than the control group (MDI 8.5mm; control 6.1 mm) (p < 0.01). The inferior, posteroinferior, and posterior dimensions (posterior-inferior quadrant, 3 to 6 o’clock position for left shoulder) of the glenohumeral joint capsule were significantly greater in the MDI group (inferior 24.5mm; posteroinferior 26.4 mm, posterior 22.5 mm) than in the control group (inferior 20.4mm, posteroinferior 21.9mm, posterior 19.3 mm) (p < 0.01). Rotator interval width and capsular dimensions in other directions showed no statistically significant difference between the 2 groups. Based on ROC, threshold values of 24 mm (inferior capsule) and 7.4 mm (rotator interval depth) had 70.6-73.5% sensitivity and 70.4% specificity to identify MDI patients.
Conclusions: 24 mm and 7 mm threshold values (24/7) of inferior capsule and rotator interval depth, respectively, on shoulder MR arthrography could aid in diagnosis of MDI in adolescent patients. This is the first study to objectively quantify capsular volume in adolescent patients with surgically treated MDI. This information needs to be further validated in prospective fashion.