Dupuytren's disease is a common disorder in the practice of hand surgery and is characterised by contraction of the palmar fascia. It is predominantly seen in the Celtic population. The treatment is essentially surgical but this is associated with a high recurrence rate. Present-day research is directed at the myofibroblast, which is thought to be the central cellular mechanism responsible for Dupuytren's disease. This paper offers a review of the literature and highlights new areas of research into this condition.
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References
1.
AbbottX, DenneyJ, BurkeF (1987): A review of attitudes to splintage in Dupuytren's contracture. Journal of Hond Surgery12B: 326–328
2.
AbercrombieM, FlintMH, JamesDW (1956): Wound contraction in relation to collagen formation in scorbutic guinea pigs. Journal of Embryology and Experimental Morphology4:67
3.
AnHS, SouthworthSR, JacksonT (1988): Cigarette smoking and Dupuytren's contracture of the hand. Journal of Hand Surgery13A: 872
4.
AndrewJG (1991): Contraction of the proximal interphalangeal joint in Dupuytren's disease. Journal of Hood Surgery16B: 446–448
5.
BadalamenteM, HurstL (1996): Enzyme injection as a non-operative treatment for Dupuytren's disease. Drug Delivery.3: 33–40
6.
BadalamenteM, HurstL (2000): Enzyme injection as nonsurgical treatment of Dupuytren's disease. Journal of Hand Surgery25A:4: 629–636
7.
Brickley-ParsonsD, GlimcherMJ, SmithRJ (1981): Biochemical changes in the collagen of the palmas fascia in patients with Dupuytren's disease. Journal of Bone & Joint Surgery (Am).63: 787–797
8.
BurgeP (1999): Genetics of Dupuytren's disease. Hand Clinics.15(1): 63–71
9.
BurkeFD, McGroutherDA, SmithPJ (1990): Dupuytren's disease. In Principles of Hand Surgery, Edinburgh, Churchill Livingstone
10.
CrowleyB, TonkinMA (1999); The proximal interphalangeal joint in Dupuytren's disease. Hand Clinics15 (1): 137–147
11.
DupuytrenG (1831): De la retraction des doigts par suite d'une affection de l-ponevrose palmaire. Description de la maladie. Operation chirurgicale qui convient dans de cas. J Univ Hebd Med Chirprat.5: 352–365
12.
ElliotD (1999): The Early History of Dupuytrens disease. Hand Clinics.15(1): 1–19
13.
ErdmannM, QuabaA, SommerladB (1995): Epithelioid sarcoma masquerading as Dupuytren's disease. British Journal of Plastic Surgery.48: 39–42
14.
GabbianiG, MajnoG (1972): Dupuytren's contracture: fibroblast contraction? An ultrastructural study. American Journal of Pathology.66: 131–46
15.
GassetJ (1985). Dupuytren's disease and the anatomy of the palmodigital aponeurosis. In HuestonJ, TubianaRDupuytren's disease.2nd edition, London, Churchill Livingstone.
16.
HakistanR (1974): Late results of extensive fasciectomy. In HuestonJ, TabianaR (eds): Dupuytren's disease.New York, Grune and Stratton
HuestonJT (1984): “Firebreaks” grafts in Dupuytren's contracture. Aust NZ Journal of Surgery.54: 277–281
21.
HuestonJ, SeyferA (1991): Some medicalegal aspects of Dupuytren's contracture. Hand Clinks.7:617
22.
HurstLC, BadalamenteMA (1999): Hon-operative treatment of Dupuytren's disease. Hand Clinics.15(1): 97–107
23.
KloenP (1999): New insights in the development of Dupuytren's contracture: a review. British Journal of Plastic Surgery.52(8): 629–635
24.
LuckJV (1959): Dupuytren's disease: A new concept of the pathogenesis correlated with surgical management. Journal of Bone & Joint Surgery (Am).41:635
25.
LundH (1941): Duputren's contracture and epilepsy. Arts Psychiatrica et Neurologica16: 465
26.
Maslieurat-LagemardGE (1839): De L'anatomie descriptive et chirugicale des aponevoroses et des membranes synoviales de la main, de leur application a la therapeutigue et a la medecine operatoire. Gazette Medicate de Paris.7: 273–280
27.
McCashCR (1964): The open palm technique in Dupuytren's contracture. British Journal of Plastic Surgery17: 271–280
28.
Mc FarlaneR, BotzJ, CheungH (1990): Epidemiology of surgical patients. In Mc FarlaneR, McGroutherD, FlintM (eds): Dupuytren's disease: Biology and Treatment.Edinburgh, Churchill Livingstone
29.
Mc FarlaneR, McGroutherD, FlintM (1990): Dupuytren's disease, Edinburgh, Churchill Livingstone
30.
McGroutherDA (1985): The microanatomy of Dupuytrens disease. En HuestonJT, TubianaR (eds): Dupuytren's disease.Edinburgh: Churchill Livingstone
31.
MobergE (1973): Three useful ways to avoid amputation in advanced Dupuytren's contracture. Orthop Clin North Am4: 1001
32.
MullinsPA (1999): Postsurgical rehabilitation of Dupuytren's disease. Hand Clinics15(1): 167–174
33.
NobleJ, ArafaM, HoyleG (1992): The association between alcohol, hepatic pathology and Dupuytren's disease. Journal of Hand Surgery17B: 71
34.
NobleJ, HeathcoteJG, CohenH (1984): Diabetes mellitus in the aetiology of Dupuytren's disease. Journal of Bone & Joint Surgery (Br).66: 322
35.
RossDC (1999): Epidemiology of Dupuytren's disease. Hand Clinics15(1): 53–62
36.
RowleyDI, CouchM, ChesneyRB (1984): Assessment of percutaneous fasciotomy in the management of Dupuytren's contracture. Journal of Hand Surgery9B: 163–166
37.
SchneiderLH, RankinFM, EisenbergT (1986): Surgery of Dupuytren's disease: A review of the open palm method. Journal of Hand Surgery11A: 23–27
38.
SkoogT (1967): The transverse elements of the palmar aponeurosis in Dupuytren's contracture. Scandonavian Journal of Plastic Reconstrctuve Surgery1: 51–63
39.
SmithAC (1991): Diagnosis and Indications for Surgical Treatment. Hand Clinics7(4): 635–642
40.
StricklandJW, LeibovicSJ (1991): Anatomy and pathogenesis of the digital cords and nodules. Hand Clinics7(4): 645–657
