Asukai, Y., Valladares, A., Camps, C., Wood, E., Taipale, K., Arellano, J. et al. (2010) Cost-effectiveness analysis of pemetrexed versus docetaxel in the second-line treatment of non-small cell lung cancer in Spain: results for the non-squamous histology population. BMC Cancer10: 26.
2.
Azzoli, C.G., Baker Jr, S., Temin, S., Pao, W., Aliff, T., Brahmer, J. et al. (2009) American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for stage IV non-small cell lung cancer. J Clin Oncol27: 6251-6266.
3.
Belani, C.P., Lee, J.S., Socinski, M.A., Robert, F., Waterhouse, D., Rowland, K. et al. (2005) Randomized phase III trial comparing cisplatin-etoposide to carboplatin-paclitaxel in advanced or metastatic non-small cell lung cancer . Ann Oncol16: 1069-1075.
4.
Brodowicz, T., Krzakowski, M., Zwitter, M., Tzekova, V., Ramlau, R., Ghilezan, N. et al. (2006) Cisplatin and gemcitabine first-line chemotherapy followed by maintenance gemcitabine or best supportive care in advanced non-small cell lung cancer: a phase III trial. Lung Cancer52: 155-163.
5.
Cappuzzo, F.C.T., Stelmakh, L., Cicenas, S., Szczesna, A., Juhasz, E. and Esteban Gonzalez, E. et al., on behalf of the SATURN Investigators ( 2009) SATURN: A double-blind, randomized, phase III study of maintenance erlotinib versus placebo following nonprogression with first-line platinum-based chemotherapy in patients with advanced NSCLC. J Clin Oncol27(Suppl): Abstract 8001.
6.
Carlson, J.J., Reyes, C., Oestreicher, N., Lubeck, D., Ramsey, S.D. and Veenstra, D.L. ( 2008) Comparative clinical and economic outcomes of treatments for refractory non-small cell lung cancer (NSCLC). Lung Cancer61: 405-415.
7.
Ciuleanu, T., Brodowicz, T., Zielinski, C., Kim, J.H., Krzakowski, M., Laack, E. et al. (2009) Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small cell lung cancer: a randomised, double-blind, phase 3 study. Lancet374: 1432-1440.
8.
Douillard, J.Y., Shepherd, F.A., Hirsh, V., Mok, T., Socinski, M.A., Gervais, R. et al. (2010) Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small cell lung cancer: data from the randomized phase III INTEREST trial. J Clin Oncol28: 744-752.
9.
Fidias, P.M., Dakhil, S.R., Lyss, A.P., Loesch, D.M., Waterhouse, D.M., Bromund, J.L. et al. (2009) Phase III study of immediate compared with delayed docetaxel after front-line therapy with gemcitabine plus carboplatin in advanced non-small cell lung cancer. J Clin Oncol27: 591-598.
10.
Fojo, T. and Grady, C.(2009) How much is life worth: cetuximab, non-small cell lung cancer, and the $440 billion question. J Natl Cancer Inst101: 1044-1048.
11.
Fossella, F., Pereira, J.R., von Pawel, J., Pluzanska, A., Gorbounova, V., Kaukel, E. et al. (2003) Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small cell lung cancer: the TAX 326 study group. J Clin Oncol21: 3016-3024.
12.
Hanna, N., Shepherd, F.A., Fossella, F.V., Pereira, J.R., De Marinis, F., von Pawel, J. et al. (2004) Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small cell lung cancer previously treated with chemotherapy . J Clin Oncol22: 1589-1597.
13.
Kim, E.S., Hirsh, V., Mok, T., Socinski, M.A., Gervais, R., Wu, Y.L. et al. (2008) Gefitinib versus docetaxel in previously treated non-small cell lung cancer (INTEREST): a randomised phase III trial. Lancet372: 1809-1818.
14.
Kobayashi, S., Boggon, T.J., Dayaram, T., Janne, P.A., Kocher, O., Meyerson, M. et al. (2005) EGFR mutation and resistance of non-small cell lung cancer to gefitinib. N Engl J Med352: 786-792.
15.
Lyseng-Williamson, K.A.(2010) Erlotinib: a pharmacoeconomic review of its use in advanced non-small cell lung cancer. Pharmacoeconomics28: 75-92.
16.
Martoni, A., Marino, A., Sperandi, F., Giaquinta, S., Di Fabio, F., Melotti, B. et al. (2005) Multicentre randomised phase III study comparing the same dose and schedule of cisplatin plus the same schedule of vinorelbine or gemcitabine in advanced non-small cell lung cancer. Eur J Cancer41: 81-92.
17.
Miller, V.A.O.C.P., Soh, C., Kabbinavar, F., and for the ATLAS Investigators ( 2009) A randomized, double-blind, placebo-controlled, phase IIIb trial (ATLAS) comparing bevacizumab (B) therapy with or without erlotinib (E) after completion of chemotherapy with B for first-line treatment of locally advanced, recurrent, or metastatic non-small cell lung cancer (NSCLC). J Clin Oncol27: Abstract LBA8002.
18.
Mok, T.S., Wu, Y.L., Thongprasert, S., Yang, C.H., Chu, D.T., Saijo, N. et al. (2009) Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma . N Engl J Med361: 947-957.
19.
Non-small Cell Lung Cancer Collaborative Group ( 1995) Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials . BMJ311: 899-909.
20.
OSI Pharmaceuticals, I.a.G., Inc. (2009) FDA Advisory Committee recommends against approving tarveva for first-line maintenance use in advanced non-small cell lung cancer.
21.
Park, J.O., Kim, S.W., Ahn, J.S., Suh, C., Lee, J.S., Jang, J.S. et al. (2007) Phase III trial of two versus four additional cycles in patients who are nonprogressive after two cycles of platinum-based chemotherapy in non-small cell lung cancer. J Clin Oncol25: 5233-5239.
22.
Pfister, D.G., Johnson, D.H., Azzoli, C.G., Sause, W., Smith, T.J., Baker Jr, S. et al. (2004) American Society of Clinical Oncology treatment of unresectable non-small cell lung cancer guideline: update 2003. J Clin Oncol22: 330-353.
23.
Reck, M., von Pawel, J., Zatloukal, P., Ramlau, R., Gorbounova, V., Hirsh, V. et al. (2009) Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small cell lung cancer: AVAil. J Clin Oncol27: 1227-1234.
24.
Rosell, R., Moran, T., Queralt, C., Porta, R., Cardenal, F., Camps, C. et al. (2009) Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med361: 958-967.
25.
Rudd, R.M., Gower, N.H., Spiro, S.G., Eisen, T.G., Harper, P.G., Littler, J.A. et al. (2005) Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small cell lung cancer: a phase III randomized study of the London Lung Cancer Group . J Clin Oncol23: 142-153.
26.
Sandler, A., Gray, R., Perry, M.C., Brahmer, J., Schiller, J.H., Dowlati, A. et al. (2006) Paclitaxel-carboplatin alone or with bevacizumab for non-small cell lung cancer. N Engl J Med355: 2542-2550.
27.
Scagliotti, G., Hanna, N., Fossella, F., Sugarman, K., Blatter, J., Peterson, P. et al. (2009) The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies. Oncologist14: 253-263.
28.
Scagliotti, G.V., De Marinis, F., Rinaldi, M., Crino, L., Gridelli, C., Ricci, S. et al. (2002) Phase III randomized trial comparing three platinum-based doublets in advanced non-small cell lung cancer. J Clin Oncol20: 4285-4291.
29.
Scagliotti, G.V., Parikh, P., von Pawel, J., Biesma, B., Vansteenkiste, J., Manegold, C. et al. (2008) Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small cell lung cancer. J Clin Oncol26: 3543-3551.
30.
Sederholm, C., Hillerdal, G., Lamberg, K., Kolbeck, K., Dufmats, M., Westberg, R. et al. (2005) Phase III trial of gemcitabine plus carboplatin versus single-agent gemcitabine in the treatment of locally advanced or metastatic non-small cell lung cancer: the Swedish Lung Cancer Study Group. J Clin Oncol23: 8380-8388.
31.
Shepherd, F.A., Rodrigues Pereira, J., Ciuleanu, T., Tan, E.H., Hirsh, V., Thongprasert, S. et al. (2005) Erlotinib in previously treated non-small cell lung cancer. N Engl J Med353: 123-132.
32.
Socinski, M.A., Schell, M.J., Peterman, A., Bakri, K., Yates, S., Gitten, R. et al. (2002) Phase III trial comparing a defined duration of therapy versus continuous therapy followed by second-line therapy in advanced-stage IIIB/IV non-small cell lung cancer. J Clin Oncol20: 1335-1343.
33.
Soon, Y.Y., Stockler, M.R., Askie, L.M. and Boyer, M.J.(2009) Duration of chemotherapy for advanced non-small cell lung cancer: a systematic review and meta-analysis of randomized trials. J Clin Oncol27: 3277-3283.
34.
Tsao, M.S., Sakurada, A., Cutz, J.C., Zhu, C.Q., Kamel-Reid, S., Squire, J. et al. (2005) Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med353: 133-144.
35.
von Plessen, C., Bergman, B., Andresen, O., Bremnes, R.M., Sundstrom, S., Gilleryd, M. et al. (2006) Palliative chemotherapy beyond three courses conveys no survival or consistent quality-of-life benefits in advanced non-small cell lung cancer. Br J Cancer95: 966-973.
36.
Westeel, V., Quoix, E., Moro-Sibilot, D., Mercier, M., Breton, J.L., Debieuvre, D. et al. (2005) Randomized study of maintenance vinorelbine in responders with advanced non-small cell lung cancer. J Natl Cancer Inst97: 499-506.