Hirsutism is a condition marked by excess terminal hair growth in women in areas like the upper lip, chin, abdomen, back, and thighs. This dark, coarse hair may signify hormonal imbalances, particularly elevated androgens, and may be linked to conditions such as polycystic ovary syndrome, adrenal hyperplasia, or medications affecting hormone levels. Diagnosis and management involve identifying the underlying cause and may include hormonal therapies, lifestyle changes, and cosmetic treatments to control hair growth. This article aims to summarise the causes, differential diagnosis, investigation, and treatment options for hirsuitism affecting patients presenting in primary care.
CarminaEKoyamaTChangL, et al. (1992)
Does ethnicity influence the prevalence of adrenal hyperandrogenism and insulin resistance in polycystic ovary syndrome?American Journal of Obstetrics & Gynaecology167(6): 1807. DOI: 10.1016/0002-9378(92)91779-a.
3.
CavlanDBharwaniNGrossmanA (2010)
Androgen- and estrogen-secreting adrenal cancers. Seminars in Oncology37(6): 638–648. DOI: 10.1053/j.seminoncol.2010.10.016.
4.
DemidovVNLipatenkovaOVikharevaC, et al. (2008)
Imaging of gynecological disease (2): Clinical and ultrasound characteristics of Sertoli cell tumors, Sertoli-Leydig cell tumors and Leydig cell tumors. Ultrasound in Obstetrics & Gynaecology31(1): 85–91. DOI: 10.1002/uog.5227.
5.
Escobar-MorrealeHFCarminaEDewaillyD, et al. (2012)
Epidemiology, diagnosis and management of hirsutism: A consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society. Human Reproduction Update18(2): 146–170. DOI: 10.1093/humupd/dmr042.
6.
KirschnerMASamojlikESilberD (1983)
A comparison of androgen production and clearance in hirsute and obese women. Journal of Steroid Biochemistry19(1B): 607–614. DOI: 10.1016/0022-4731(83)90225-x
