Psoriasis is a chronic inflammatory condition with a relapsing and remitting course. It has a complex aetiology, involving genetic, environmental and immunological components. Psoriasis has important associations with arthritis and cardiovascular disease, therefore a comprehensive understanding of the condition is important for all GPs. Psycho-social wellbeing is also commonly affected. A wide variety of topical treatments for psoriasis can be initiated in primary care, alongside assessment and treatment of conditions associated with the disease.
British Association of Dermatologists (2016) British Association of Dermatologists’ guidelines for the safe and effective prescribing of methotrexate for skin disease 2016. Available at: www.bad.org.uk/shared/get-file.ashx?id=4020&itemtype=document (accessed 27 April 2018).
Greb JE, Goldminz AM, Elder JT, et al. (2016) Psoriasis. Nature Reviews Disease Primers 2: 16082. DOI: 10.1038/nrdp.2016.82.
6.
HawkesJEChanTCKrueger JamesG (2017) Psoriasis pathogenesis and the development of novel targeted immune therapies. The Journal of Allergy and Clinical Immununology140(3): 545–653. DOI: 10.1016/j.jaci.2017.07.004.
7.
HorreauCPouplardCBrenautEet al.(2013) Cardiovascular morbidity and mortality in psoriasis and psoriatic arthritis: A systematic literature review. Journal of the European Academy of Dermatology and Venereology27: 12–29. DOI: 10.1111/jdv.12163.
8.
KimWBJeromeDYeungJ (2017) Diagnosis and management of psoriasis. Canadian Family Physician63(4): 278–285. Available at: www.cfp.ca/content/63/4/278 (accessed 27 April 2018).
9.
KurdSKTroxelABCrits-ChristophPet al.(2010) The risk of depression, anxiety, and suicidality in patients with psoriasis: A population-based cohort study. Archives of Dermatology146(8): 891–895. DOI: 10.1001/archdermatol.2010.186.
10.
Martínez-GarcíaEArias-SantiagoSValenzuela-SalasIet al.(2014) Quality of life in persons living with psoriasis patients. Journal of American Academy of Dermatology71(2): 302–307. DOI: 10.1016/j.jaad.2014.03.039.
11.
MoonHMizaraAMcBrideSR (2013) Psoriasis and psycho-dermatology. Dermatology and Therapy3(2): 117–130. DOI: 10.1007/s13555-013-0031-0.
12.
NelsonPAKaneKChisholmAet al.(2016) ‘I should have taken that further’ – missed opportunities during cardiovascular risk assessment in patients with psoriasis in UK primary care settings: A mixed-methods study. Health Expectations19(5): 1121–1137. DOI: 10.1111/hex.12404.
OgdieAGelfandJM (2015) Clinical risk factors for the development of psoriatic arthritis among patients with psoriasis: A review of available evidence. Current Rheumatology Reports17(10): 64. DOI: 10.1007/s11926-015-0540-1.
15.
OgdieAWeissP (2015) Epidemiology of psoriatic arthritis. Rheumatic Diseases Clinics of North America41(4): 545–568. DOI: 10.1016/j.rdc.2015.07.001.
SamarasekeraEJNeilsonJMWarrenRBet al.(2013) Incidence of cardiovascular disease in individuals with psoriasis: A systematic review and meta-analysis. The Journal of Investigative Dermatology133(10): 2340–2346. DOI: 10.1038/jid.2013.149.
18.
ShahwanKTKimballAB (2015) Psoriasis and cardiovascular disease. Medical Clinics of North America99(6): 1227–1242. DOI: 10.1016/j.mcna.2015.08.001.
19.
SpringateDAParisiRKontopantelisEet al.(2017) Incidence, prevalence and mortality of patients with psoriasis: A U.K. population-based cohort study. British Journal of Dermatology176(3): 650–658. DOI: 10.1111/bjd.15021.
ZengJLuoSHuangYet al.(2017) Critical role of environmental factors in the pathogenesis of psoriasis. The Journal of Dermatology44: 863–872. DOI: 10.1111/1346-8138.13806.
