Amenorrhoea

Abstract

Amenorrhoea is the absence of menstruation in a female patient of reproductive age. Patients with amenorrhoea may be concerned about puberty and fertility depending on the age of presentation. It is important for clinicians to consider the underlying causes and appropriately assess, investigate and counsel each patient. Approximately 0.3% of females experience primary amenorrhoea, and 3–4% of females at reproductive age experience secondary amenorrhoea. This article aims to outline the differential diagnoses for both primary and secondary amenorrhoea and to consider investigation and management in primary care, including indications for referral to secondary care.