Connective tissue diseases are a rare and diverse group of disorders that result in pathology of the connective tissues of the body. This article focuses on the systemic autoimmune connective tissue diseases, and aims to provide a practical overview of these conditions for use in primary care.
BakstRMerolaJFFranksAGSanchezM (2008) Raynaud’s phenomenon: Pathogenesis and management. Journal of the American Academy of Dermatology, 59(4): 633–653.
3.
BowmanSIbrahimGHolmesGHamburgerJAinsworthJR (2004) Estimating the prevalence among Caucasian women of primary Sjögren’s syndrome in two general practices in Birmingham, UK. Scandinavian Journal of Rheumatology, 33(1): 39–43. doi: 10.1080/03009740310004676.
NashRAMcSweeneyPACroffordLJAbidMChenCSGodwinD… FurstDE (2007) High-dose immunosuppressive therapy and autologous hematopoietic cell transplantation for severe systemic sclerosis: long-term follow-up of the US multicenter pilot study. Blood, 110: 1388–1396. doi: 10.1182/blood-2007-02-072389.
10.
Ortega-Hernandez OD & Shoenfeld Y. Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment. Best Practice and Research Clinical Rheumatology 26, 61–72. doi: 10.1016/j.berh.2012.01.009.
11.
PostlethwaiteAEHarrisLJRazaSHKoduraSAkhigbeT (2012) Pharmacotherapy of systemic sclerosis. Expert Opinion on Pharmacotherapy, 11(5): 789–806. doi: 10.1517/14656561003592177.
Shanmugam VK & Steen VD. (2010). Renal manifestations in scleroderma: evidence for subclinical renal disease as a marker of vasculopathy. International Journal of Rheumatology 1–8. doi: 10.1155/2010/538589.
16.
TanEMCohenASFriesJFMasiATMcShaneDJRothfieldNF… WinchesterRJ (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis and Rheumatism, 25: 1271–1277. doi: 10.1002/art.1780251101.
17.
TanEMFeltkampTEWSmolenJSButcherBDawkinsRFritzlerMJ… KoziolJA (1997) Range of antinuclear antibodies in “healthy” individuals. Arthritis and Rheumatism, 40(9): 1601–1611. doi: 10.1002/art.1780400909.
18.
UrmanJDLowensteinMBAbelesMWeinsteinA (1978) Oral mucosal ulceration in systemic lupus erythematosus. Arthritis and Rheumatism, 21: 58–61. doi: 10.1002/art.1780210110.
