Fanconi anaemia is a rare autosomal recessive chromosomal instability syndrome characterised by progressive bone marrow failure, skeletal defects, reduced fertility and increased susceptibility to malignancy. Successful pregnancy in both transplanted and non-transplanted patients have been recorded. In this paper, we present a woman diagnosed with Fanconi anaemia and who had a spontaneous conception at the age of 25 years with an uneventful delivery at 38 weeks of pregnancy.
ScarrCATreharneAConnerC, et al. Fanconi anaemia complicating pregnancy – treatment and management of critical thrombocytopenia and anaemia. Arch Dis Child2014; 306576: 412.
2.
AlterBPFrissoraCLHalpeirinDS.Fanconi’s anaemia and pregnancy. Br J Haematol1991;
77: 410–418.
3.
SorbiFMecacciFDi FilippoA, et al.
Pregnancy in Fanconi anaemia with bone marrow failure: a case report and review of the literature. BMC Pregnancy Childbirth2017;
17: 53.
4.
TischkowitzMDookalI.Fanconi anaemia and leukaemia – clinical and molecular aspects. Br J Haematol2004;
126: 176–191.
5.
WajnrajchMPGertnerJMHumaZ, et al.
Evaluation of growth and hormonal status in patients referred to the International Fanconi Anaemia Registry. Paediatrics Blood and Cancer2001;
107: 744–754.
6.
Riveros-Perez HermeschAC, et al.
Aplastic anaemia during pregnancy: a review of obstetrics and anaesthetic consideration.Int J Womens Health2018;
10: 117–125.
7.
CLASP trial.A randomised trial of low dose aspirin for the prevention and treatment of pre-eclampsia among 9364 pregnant women. Lancet1994;
343: 619–629.
8.
PeckTEHillFA.Pharmacology for anaesthesia and intensive care. 4th edCambridge:
Cambridge2014, p.110.
