Hand surgeons have the potential to improve patient care, both with their own research and by using evidenced-based practice. In this first part of a two-part article, we describe key steps for the analysis of clinical data using quantitative methodology. We aim to describe the principles of medical statistics and their relevance and use in hand surgery, with contemporaneous examples. Hand surgeons seek expertise and guidance in the clinical domain to improve their practice and patient care. Part of this process involves the critical analysis and appraisal of the research of others.
DaviesJRobertsTLimbRMatherDThorntonDWadeRG.Time to surgery for open hand injuries and the risk of surgical site infection: a prospective multicentre cohort study. J Hand Surg Eur. 2020,
45: 622–8.
8.
HooperG.Tables and charts in the journal. J Hand Surg Eur. 2019,
44: 436–8.
9.
JohnsonNASimcockGLRyeDDiasJJ.Change in capitate shift after osteotomy for distal radial fracture malunion. J Hand Surg Eur. 2023,
48: 798–802.
10.
MatejkaJFitzmauriceG. Same stats, different graphs: generating datasets with varied appearance and identical statistics through simulated annealing. Proceedings of the 2017 CHI conference on human factors in computing systems. https://dl.acm.org/doi/10.1145/3025453.3025912#sec-cit (17th May 2023).
OeckenpöhlerSWieskötterBAitzetmüllerMKlietzMLRoyeckTLangerMF.Scapholunate ligament reconstruction using a part of the extensor carpi radialis brevis tendon through a dorsal approach. J Hand Surg Eur. 2023,
48: 303–8.
13.
PedersenABMikkelsenEMCronin-FentonD, et al.
Missing data and multiple imputation in clinical epidemiological research. Clin Epidemiol. 2017,
9: 157–66.
14.
RaghunathanT.Missing data analysis in practice.
Ann Arbor,
CRC Press, 2016: 9.
15.
StirlingPHCHarrisonSJMcEachanJE.The effect of diabetes mellitus on the outcome of surgery for cubital tunnel syndrome. J Hand Surg Eur. 2023,
48: 316–20.
16.
StirlingPHCJenkinsPJNgNClementNDDuckworthADMcEachanJE.Nonresponder bias in hand surgery: analysis of 1945 cases lost to follow-up over a 6-year period. J Hand Surg Eur. 2022,
47: 197–205.
17.
StuntJJBroekstraDCde BoerMR.Statistics in publishing: the (mis)use of the p-value (Part 2). J Hand Surg Eur. 2022,
47: 1092–5.
18.
TextorJvan der ZanderBGilthorpeMLiśkiewiczMEllisonG.Robust causal inference using directed acyclic graphs: the R package ‘dagitty’. Intl J Epidemiol. 2016,
45: 1887–94.
19.
WhiteIRCarlinJB.Bias and efficiency of multiple imputation compared with complete-case analysis for missing covariate values. Stat Med. 2010,
29: 2920–31.