We describe the case of a 31-year-old man admitted to the intensive care unit (ICU) with hypercapnia and hypoxia secondary to Aspergillosis, Pneumocystis jirovecii pneumonia and tuberculosis. The patient was treated with conventional lung-protective ventilation strategies. He subsequently had a Novalung® interventional lung assist membrane ventilator (iMV) inserted due to worsening hypercapnia. His condition initially improved; however eight days after insertion the iMV appeared to be associated with worsening oxygenation.
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