ICS Medal and Research Abstract Presentations

Wajant H Pfizenmaier K Scheurich P . Tumor necrosis factor signaling. Cell Death Differ 2003;10: 45–65.

Wilson MR Goddard ME O'Dea KP . Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice. Am J Physiol Lung Cell Mol Physiol 2007;293: L60–8.

Bertok S Wilson MR Morley PJ . Specific inhibition of intra-alveolar p55 TNF receptor signalling by a domain antibody attenuates ventilator-induced lung injury in mice. Intensive Care Med 2010;36: S196.

Wilson MR O'Dea KP Zhang D . Role of lung-marginated monocytes in an in vivo mouse model of ventilator-induced lung injury. Am J Respir Crit Care Med 2009;179: 914–22.

Wilson MR Choudhury S Goddard ME . High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury. J Appl Physiol 2003;95: 1385–93.

World Health Organisation. The Top Ten Causes of Death. 2004.(Accessed 21/06/2011, 2011, at http://www.who.int/mediacentre/factsheets/fs310/en/index.html.).

Nolan JS Zideman J. Biarent AD . European Resuscitation Council Guidelines for Resuscitation 2010. Section 1. Executive Summary. Resuscitation 2010;81: 1219–76.

Kramer-Johansen J Myklebust H Wik L . Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional study. Resuscitation 2006;71: 283–92.

Wik L . Rediscovering the importance of chest compressions to improve the outcome from cardiac arrest. Resuscitation 2003;58: 267–69.

Abella B Alvarado J Myklebust H . Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. JAMA 2005;293: 305–10.

Wik L Kramer-Johansen J Myklebust H . Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrest. JAMA 2005;293: 299–304.

Wik L Steen PA Bircher NG . Quality of bystander cardiopulmonary resuscitation influences outcome after prehospital cardiac arrest. Resuscitation 1994;28: 195–203.

Abella BS Edelson DP Kim S . CPR quality improvement during in-hospital cardiac arrest using a real-time audiovisual feedback system. Resuscitation 2007;73: 54–61.

Yeung J Meeks R Edelson D . The use of CPR feedback/prompt devices during training and CPR performance: A Systematic Review. Resuscitation 2009;80: 743–51.

Soar JM Ballance KG Barelli JHW . European Resuscitation Council Guidelines for Resuscitation 2010 Section 9. Principles of education in resuscitation. Resuscitation 2010;81: 1434–44.

Napier F Davies RP Baldock C . Validation for a scoring system of the ALS cardiac arrest simulation test (CASTest). Resuscitation 2009;80: 1034–8.

Cooper S Wakelam A . Leadership of resuscitation teams: ‘Lighthouse Leadership’. Resuscitation 1999;42: 27–45.

Gausche M Lewis RJ Stratton SJ . Effect of out-of-hospital pediatric endotracheal intubation on survival and neurological outcome: a controlled clinical trial. JAMA 2000;283: 783–90.

Hanif MA Kaji AH Niemann JT . Advanced airway management does not improve outcome of out-of-hospital cardiac arrest. Acad Emerg Med 2010;17: 926–31.

Jemmett ME Kendal KM Fourre MW . Unrecognised misplacement of endotracheal tubes in a mixed urban to rural emergency medical services setting. Acad Emerg Med 2003;10: 961–65.

Nolan JP Soar J . Airway techniques and ventilation strategies. Curr Opin Crit Care 2008;14: 279–86.

Shyamsundar M McKeown ST O'Kane CM . Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. Am J Respir Crit Care Med 2009;179: 1107–14.

Millikan KW Silverstein J Hart V . A 15-year review of esophagectomy for carcinoma of the esophagus and cardia. Arch Surg 1995;130: 617–24.

Tandon S Batchelor A Bullock R . Peri-operative risk factors for acute lung injury after elective oesophagectomy. Br J Anaesth 2001;86: 633–38.

Rocker GM Wiseman MS Pearson D . Neutrophil degranulation and increased pulmonary capillary permeability following oesophagectomy: A model of early lung injury in man. Br J Surg 1988;75: 883–86.

Moloney ED Mumby SE Gajdocsi R . Exhaled breath condensate detects markers of pulmonary inflammation after cardiothoracic surgery. Am J Respir Crit Care Med 2004;169: 64–69.

Koh KK Ahn JY Jin DK . Comparative effects of statin and fibrate on nitric oxide bioactivity and matrix metalloproteinase in hyperlipidemia. Int J Cardiol 2004;97: 239–44.

Jacobson JR Barnard JW Grigoryev DN . Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury. Am J Physiol Lung Cell Mol Physiol 2005;288: L1026–32.

Barazzone C Donati YR Rochat AF . Keratinocyte growth factor protects alveolar epithelium and endothelium from oxygen-induced injury in mice. Am J Pathol 1999;154: 1479–87.

Lee JW Fang X Gupta N . Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci USA 2009;106: 16357–62.

Veenith TV Rana M Ercole A . A[H1N1] flu and refractory hypoxaemia: Is extracorporeal lung support the holy grail? Thorax 2011;66: 836–37.

Girard MP Tam JS Assossou OM Kieny MP . The 2009 A (H1N1) influenza virus pandemic: a review. Vaccine 2010;28: 4895–902.

Craig T Duffy M Shyamsundar M . A randomized clinical trial of hydroxymethylglutaryl-coenzyme A reductase inhibition for acute lung injury (The HARP Study). Am J Resp Crit Care Med 2011;183: 620–26.

Van der Voort . An observational study on the effects of nadroparin-based and citrate-based continuous venovenous hemofiltration on calcium metabolism. Blood Purif 2007;25: 267–73.

Wang PL . Bone resorption and “relative” immobilization hypercalcaemia with prolonged continuous renal replacement therapy and citrate anticoagulation. Am J Kidney Dis 2004;44: 1110–14.

Hébert PC . A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999;340: 409–17.

Cavallazzi R Marik PE . Association between time of admission to the ICU and mortality: a systemic review and meta-analysis. Chest 2010;138: 68–75.

Afessa B Gajic O . Association between ICU admission during morning rounds and mortality. Chest 2009;136: 1489–95.

Meynaar I van der Spoel J Rommes J . Off hour admission to an intensivist-led ICU is not associated with increased mortality. Crit Care 2009;13: R84–91.

Mercier E Giraudeau B Ginies G . Iatrogenic events contributing to ICU admission: a prospective study. Intensive Care Med 2010;36: 1033–37.

Lehmann LS Puopolo AL Shaykevich S . Iatrogenic events resulting in intensive care admission: Frequency, cause, and disclosure to patients and institutions. Am J Med 2005;118: 409–13.

Nolan T Resar R Haraden C Griffin FA . Improving the Reliability of Health Care. IHI Innovation Series. Boston: Institute for Healthcare Improvement; 2004.

Nelson E Batalden P Godfrey M . Quality by Design: A Clinical Microsystems Approach. Jossey Bass; 1st edition. 2007.

Sykes A . An investigation of the microbiological contamination of ultrasound equipment. Br J Infection Control 2006;7:.

Fowler C . McCracken D. US probes: risk of cross infection and ways to reduce it – comparison of cleaning methods. Radiology 1999;213: 299–300.

Dreyfuss D Saumon M . Ventilator-induced lung injury: Lessons from experimental studies. Am J Respir Crit Care Med 1998;157: 294–323.

Vincent JL Baron JF Reinhart K . Anemia and blood transfusion in critically ill patients. JAMA 2002;288: 1499–507.

Astles T . Iatrogenic anaemia in the critically ill: a survey of the frequency of blood testing in a teaching hospital intensive care unit. JICS 2009;10: 279–81.

Cuthbertson BH Rajalingam Y Harrison S . The outcome of haematological malignancy in Scottish intensive care units. JICS 2008;9: 135–40.

Ferreira FL Bota DP Bross A . Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA 2001;286: 1754–58.

Yee B Naik VN Joo HS . Nontechnical skills in anesthesia crisis management with repeated exposure to simulation-based education. Anaesthesiology 2005;103: 241–48.

Kurrek MM Fish KJ . Anaesthesia crisis resource management training: an intimidating concept, a rewarding experience. Can J Anaesth 1996;43: 430–34.

Resuscitation Council (UK). Resuscitation Guidelines. In: Nolan JP , ed. 2010: pg 69–72. www.resus.org.

K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification and Stratification. Am J Kidney Dis 2002;39: S1–S266.

Volk H Reinke P Krausch D . Monocyte deactivation-rationale for a new therapeutic strategy in sepsis. Intensive Care Med 1996;22: S474–81.

Black R Rauch C Kozlosky C . A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 1997;385: 729–33.

Alvarez-Iglesias A Wayne G O'Dea KP . Continuous real-time measurement of tumour necrosis factor-α converting enzyme activity on live cells. Lab Invest 2005;85: 1440–48.

Scott A O'Dea KP O'Callaghan D . Reactive oxygen species and p38 MAPK mediate TNF-alpha converting enzyme (TACE/ADAM17) activation in primary human monocytes. J Biol Chem 2011: Epub 26/08/2011.

Bouchon A Facchetti F Weigand MA Colonna M . TREM-1 amplifies inflammation and is a crucial mediator in septic shock. Nature 2001;410: 1103–07.

Beirne P Pantelidis P Charles P . Multiplex immune serum profiling in sarcoidosis and systemic sclerosis. Eur Respir J 2009;34: 1376–82.

De Jonghe . Crit Care Med 2007;35: 2007–15.

Vinge . Brit J Surg 1996;83360–63.

Poulsen JB . Crit Care Med 2011;39: 456–61.

Rodriquez PO . J Crit Care 2011;in press.

Gerovasili . Crit Care 2009;13: 1466–69.

A Code of Practice for the Diagnosis and Confirmation of Death. Academy of the Medical Royal Colleges. 2008; Available from: http://www.ics.ac.uk/intensive_care_professional/organ_donation.

Hoffenberg R . Christiaan Barnard: his first transplants and their impact on concepts of death. BMJ 2001;323: 1478–80.

Bell D Murphy P . Barriers to brainstem death testing and organ donation can be addressed. Anaesthesia 2010;65: 646–47.

Hsieh S-T . Brain death worldwide: Accepted fact but no global consensus in diagnostic criteria. Neurology 2006;67: 919–22.

Bell MDD Moss E Murphy PG . Brainstem death testing in the UK—time for reappraisal? Br J Anaesth. 2004;92: 633–40.

Parisi JE Kim RC Collins GH Hilfinger MF . Brain death with prolonged somatic survival. N Engl J Med 1982;306: 14–6.

Powner DJ Bernstein IM . Extended somatic support for pregnant women after brain death. Crit Care Med 2003;31: 1241–49.

Webb AC Samuels OB . Reversible brain death after cardiopulmonary arrest and induce hypothermia. Crit Care Med 2011;39: 1538–42.

Dupes B Gayet-Declacroix M Villers D . Diagnosis of brain death using two-phase spiral CT. Am J Neuroradiol 1998;19: 641–47.

Frampas E. Videcoq M. de Kerviler E.F. . CT angiography for brain death diagnosis. Am J Neuroradiol 2009;30: 1566–70.

Potts M Evans DW . Does it matter that organ donors are not dead? Ethical and policy implications. J Med Ethics 2005;31: 406–09.