DellingerRPLevyMMCarletJM. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Special Article. Crit Care Med2008;36: 296–327.
LevyMMDellingerRPTownsendSR. The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Crit Care Med2010;38: 1–8.
6.
DaviesAGreenCHuttonJ. Severe sepsis: a European estimate of the burden of disease in ICU. Intensive Care Med2001;27(Suppl 2):S284.
7.
EstebanAFrutos-VivarFFergusonND. Sepsis incidence and outcome: contrasting the intensive care unit with the hospital ward. Crit Care Med2007;35: 1284–89.
8.
KarlssonSVarpulaMRuokonenE. Incidence, treatment and outcome of severe sepsis in ICU-treated adults in Finland- the Finnsepsis Study. Intensive Care Med2007;33: 435–43.
9.
BlancoJMuriel-BombinASagredoV. Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multi-centre study. Crit Care2008;12: R158.
10.
DanielsR. Surviving the first hours in sepsis: getting the basics right. J Antimicrob Chemother2011;66 (s2):ii11–ii13.
11.
KumarARobertsDWoodKE. Duration of hypotension prior to initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med2006;34: 1589–96.
12.
FunkDJKumarA. Antimicrobial therapy for life-threatening infections: speed is life. Crit Care Clin2011;27: 53–76.
13.
GaieskiDFMikkelsenMEBandRA. Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. Crit Care Med2010;38: 1045–53.
14.
DanielsRNutbeamTMcNamaraGGalvinC. The sepsis six and the severe sepsis resuscitation bundle: a prospective observational study. Emerg Med J2011;28: 507–12.
15.
PuskarichMATrzeciakSShapiroNI. Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol. Crit Care Med2011;39: 2066–71.
16.
SeymourCWCookeCRMikkelsenME. Out-of-hospital fluid in severe sepsis: Effect on early resuscitation in the emergency department. Prehosp Emerg Care2010;14: 145–52.
17.
VincentJ-LSakrYSprungCL. Sepsis in European intensive care units: Results of the SOAP study. Crit Care Med2006;34: 354–53.
18.
RussellJAWalleyKRSingerJ. for the VASST Investigators. Vasopressin versus norepinephrine infusion in patients with septic shockNew Engl J Med2008;358: 877–87.