With the increasing use of oral anticoagulation therapy the appropriate management of perioperative anticoagulation is of surgical importance. There is a delicate balance between the risk of a perioperative thromboembolic event and the risk of operative bleeding from anticoagulation. Whilst there are a range of options available to the clinician, there appears to be no precise agreement about how to best manage this problem.
Antiplatelet Trialists' Collaboration1994Collaborative overview of randomised trials of antiplatelet therapy - III: Reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patientsBritish Medical Journal308235–246
2.
ArbitE, GoldbergM, Gomez-OrellanaI, MajuruS2006Oral heparin: status reviewThrombosis Journal106
3.
AutarR2003The management of deep vein thrombosis: The Autar DVT Risk Assessment Scale re-visitedJournal of Orthopaedic Nursing7114–124
4.
CannegieterSC, RosendaalFR, WintzenAR1995Optimal oral anticoagulant therapy in patients with mechanical heart valvesNew England Journal of Medicine33311–7
5.
ChengM, HuaW, ChenK, PuJ2009Perioperative anticoagulation for patients with mechanic heart valve(s) undertaking pacemaker implantationEuropace111183–1187
DunnAS, TurpieAGG2003Perioperative management of patients receiving oral anticoagulants. A systematic reviewArchives of Internal Medicine163901–908
8.
ErikssonBI, DahlOE, BüllerHR2005A new oral direct thrombin inhibitor, dabigatran etexilate, compared with enoxaparin for prevention of thromboembolic events following total hip replacement or knee replacement: BISTRO II randomised trialJournal of Thrombosis and Haemostasis3103–111
9.
HarbrechtU2011Old and new anticoagulantsHamostaseologie3121–27
10.
HewittRL, ChunKL, FlintLM1999Current clinical concepts in perioperative anticoagulationThe American Surgeon65270–273
11.
HirshJ, WarkentinTE, RaschkeR1998Heparin and low molecular-weight heparin. Mechanisms of action, pharmokinetics, dosing considerations, monitoring, efficacy and safetyChest114S489–S510
12.
KearonC, HirshJ1997Management of anticoagulation before and after elective surgeryNew England Journal of Medicine3361506–1511
13.
KnepperJ, RamacciottiE, WakefieldTW2011Novel anticoagulants: a discussion of clinical use in the treatment and prevention of venous thromboembolismPhlebology263–7
14.
Lazo-LangnerA, RodgerMA, WellsPS2009Lessons from ximelagatran: issues for future studies evaluating new oral direct thrombin inhibitors for venous thromboembolism prophylaxis in orthopedic surgeryClinical Application in Thrombosis & Hemostasis15316–326
15.
MorrisTA, CastrejonS, DevendraG2007No difference in risk for thrombocytopenia during treatment of pulmonary embolism and deep venous thrombosis with either low-molecular-weight-heparin or unfractionated heparin: A meta-analysisChest1321131–1139
16.
National Institute for Health and Clinical Excellence2007The reduction of venous thromboembolism (deep vein thrombosis and pulmonary embolism) in patients undergoing orthopaedic surgery and other high-risk surgical proceduresLondon, NICE
17.
RochaE, Martinez-GonzalezMA, MontesR, PanizoC2000Do the low molecular weight heparins improve the efficacy and safety of the treatment of deep venous thrombosis? A meta-analysisHaematologica85935–942
18.
Scottish Intercollegiate Guidelines Network2002Guidelines 62: Prophylaxis Of venous thromboembolismEdinburgh, SIGN
19.
SingerDE, AlbersGW, DalenJE2004Antithrombotic therapy in atrial fibrillation: the Seventh ACCP Conference on Antithrombotic and Thrombolytic TherapyChest126S429–S456
20.
TurnaB, SteinRJ, SmaldoneMC2008Safety and efficacy of flexible ureterorenoscopy and holmium: YAG lithotripsy for intrarenal stones in anticoagulated casesThe Journal of Urology1791415–1419
21.
WalengaJM, JeskeWP, PrechelMM, BacherP, BakhosM2004Decreased prevalence of heparin-induced thrombocytopenia with low-molecular-weight heparin and related drugsSeminars in Thrombosis and Haemostasis3069–80
22.
WarkentinTE, RobertsRS, HirshJ, KeltonJG2003An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patientsArchives of Internal Medicine1632518–2524
23.
WarkentinTE, GreinacherA2007Heparin-induced thrombocytopenia4th editionNew York, Informa Healthcare USA
24.
WhiteRH, McKittrickT, HutchinsonR, TwitchellJ1995Temporary discontinuation of warfarin therapy: changes in the international normalized ratioAnnals of Internal Medicine12240–42