Bicyclic Organophosphorus Amides. Nucleophilic Cleavage of 1-Oxo-2,3-benzo-10-phenyl-4,7,10-triaza-1λ 5 -phosphabicyclo-[5.3.0]decane and its p -Anisyl Analogues †
Free accessResearch articleFirst published online November, 1999
Bicyclic Organophosphorus Amides. Nucleophilic Cleavage of 1-Oxo-2,3-benzo-10-phenyl-4,7,10-triaza-1λ 5 -phosphabicyclo-[5.3.0]decane and its p -Anisyl Analogues †
Methanolysis of the title substrates leads to different products depending on the conditions: in the presence of HCI both P–N bonds are broken yielding a non-cyclic phosphonic diester while the MeO- ion reacts selectively breaking the P–N(Ar) bond and yielding a cyclic, seven-membered phosphonic amidoester.
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