The syntheses of a C-4:C-6 furano-steroid by the base-catalysed cyclization of 6α-acetoxyandrost-4-ene-3,17-dione and of a C-4:C-6 tetrahydrofuran by the cyclization of 3β,6β-dihydroxy-4β-hydroxymethylandrostan-17-one, are described.
References
1.
BonserR. W., ThompsonN. T., RandallR. W., TaresonJ. E., SpaceyG. D., HodsonH. F., and GarlandL. G., Br. J. Pharmacol.1991, 103, 1237.
2.
For a review see, HansonJ. R., Nat. Prod. Rep., 1995, 12, 381.
3.
HaefligerW., KisZ., and HauserD., Helv. Chim. Acta, 1975, 58, 1620.
