Bicyclic dienones 4 are prepared in a one pot process from the reaction of 2-(acetoxymethyl)cyclohex-2-enone 1 with 1,3-dicarbonyl compounds 2 in the presence of K2CO3 in refluxing absolute ethanol.
References
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KlixR. C., and BachR. D., J. Org. Chem., 1987, 52, 580.
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Et3N (1 equiv.) was used to obtain 3d and 3e which were converted in situ by addition of K2CO3 (2 equiv.) into 4d and 4e (both equivalent to 4a), respectively; spectroscopic data for compounds 3d and 3e are consistent with those reported in ref. 4.
9.
ChamekhA., and AmriH., Tetrahedron Lett., 1998, 39, 375.
