We report the complete characterisation of all the precursors of 6-bromo-5,8-dimethylisoquinoline via the synthesis of Miller and Moock, and the synthesis of 6-bromo-4,7-dimethyl-2-(5′-Bromo-4’,7′-dimethyl)-2’,3′-dihydro-1'H-inden-1′-yl)-1H-indene.
References
1.
MillerR. B., and MoockT., Tetrahedron Lett., 1980, 21, 3319.
2.
LewisR., Ph.D Thesis, University of Wales, 1995.
3.
BraunM., and BernardC., Liebigs. Ann. Chem., 1985, 435; F. McCapra, P. D. Leeson, V. Donovan and G. Perry, Tetrahedron, 1986, 42, 3223; J. A. Elvidge and R. G. Foster, J. Chem. Soc., 1963, 590; 1964, 981; J-P. Quere and E. Maréchal, Bull. Soc. Chim. Fr., 1971, 8, 2983; B. B. Eisner and K. J. Parker; J. Chem. Soc., 1957, 592.
4.
DaviesB. R., JohnsonS. J., and WoodgateP. D., J. Chem. Soc., Perkin Trans. 1, 1985, 2545.
5.
NolandW. E., LanducciL. L., and DarlingJ. C., J. Org. Chem., 1979, 44, 1358.
6.
DansiA., and PasiniC., Chem. Abstr., 1952, 46, 5563.
7.
MoglioniA. G., TombariD. G., and IglesiasG. Y. M., J. Chem. Res., 1998, 606.
8.
GansserC., MigambanouJ., and VielC., Farm. Ed. Sci., 1985, 40, 459.
9.
BirchA. J., JacksonA. H., and ShannonP. V. R., J. Chem. Soc., Perkin Trans. 1, 1974, 2185; 2190.