Synthesis of Some Substituted Adamantane-2,4-diones from 4,4-Disubstituted Cyclohexanone Enamines and α,β-Unsaturated Acid Chlorides

Abstract

Following our previous report⁷ on the synthesis of adamantane derivatives by condensation of 4,4-disubstituted cyclohexanone enamines with α,β-unsaturated acid chlorides, we now report the synthesis of seven new substituted adamantanediones from the reactions of three cyclohexanone enamines (4, Y = phenyl, isopropenyl, methyl) in which one of the substituents is an acetyl group.