GoldsteinLBAmarencoPSzarekMCallahanA 3rdHennericiMSillesenH. Hemorrhagic stroke in the stroke prevention by aggressive reduction in cholesterol levels study. Neurology2008; 70: 2364–2370.
2.
MaedaTKawaneTHoriuchiN. Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation. Endocrinology2003; 144: 681–692.
3.
BirukovKGBochkovVNBirukovaAAKawkitinarongKRiosALeitnerA. Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac. Circ Res2004; 95: 892–901.
4.
KouklisPKonstantoulakiMVogelSBromanMMalikAB. Cdc42 regulates the restoration of endothelial barrier function. Circ Res2004; 94: 159–166.
5.
BromanMTKouklisPGaoXRamchandranRNeamuRFMinshallRD. Cdc42 regulates adherens junction stability and endothelial permeability by inducing alpha-catenin interaction with the vascular endothelial cadherin complex. Circ Res2006; 98: 73–80.
6.
KohWMahanRDDavisGE. Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling. J Cell Sci2008; 121: 989–1001.
7.
BuchnerDASuFYamaokaJSKameiMShavitJABarthelLK. pak2a mutations cause cerebral hemorrhage in redhead zebrafish. Proc Natl Acad Sci USA2007; 104: 13996–14001.
8.
LiuJFraserSDFaloonPWRollinsELVom BergJStarovic-SubotaO. A betaPix Pak2a signaling pathway regulates cerebral vascular stability in zebrafish. Proc Natl Acad Sci USA2007; 104: 13990–13995.
