SchwartzDLellouchJ. Explanatory and pragmatic attitudes in therapeutical trials. J Chronic Dis1967; 20(8): 637–648.
2.
Mc CordKAAl-Shahi SalmanRTreweekS, et al. Routinely collected data for randomized trials: promises, barriers, and implications. Trials2018; 19(1): 29.
3.
HemkensLGContopoulos-IoannidisDGIoannidisJPA. Routinely collected data and comparative effectiveness evidence: promises and limitations. CMAJ2016; 188(8): E158–E164.
4.
IoannidisJP. Why most clinical research is not useful. PLoS Med2016; 13(6): e1002049.
5.
BertagnolliMAndersonBQuinaA, et al. The electronic health record as clinical trials tool: opportunities and challenges. Clin Trials2020; 17(3): 237–242.
6.
FrobertOLagerqvistBOlivecronaGK, et al. Thrombus aspiration during ST-segment elevation myocardial infarction. N Engl J Med2013; 369(17): 1587–1597.
7.
HemkensLGSaccilottoRReyesSL, et al. Personalized prescription feedback using routinely collected data to reduce antibiotic use in primary care: a randomized clinical trial. JAMA Intern Med2017; 177(2): 176–183.
8.
HorwitzLIKuznetsovaMJonesSA. Creating a learning health system through rapid-cycle, randomized testing. N Engl J Med2019; 381(12): 1175–1179.
9.
Mc CordKAEwaldHLadanieA, et al. Current use and costs of electronic health records for clinical trial research: a descriptive study. CMAJ Open2019; 7(1): E23–E32.
10.
FitzpatrickTPerrierLShakikS, et al. Assessment of long-term follow-up of randomized trial participants by linkage to routinely collected data: a scoping review and analysis. JAMA Netw Open2018; 1(8): e186019.
11.
Llewellyn-BennettREdwardsDRobertsN, et al. Post-trial follow-up methodology in large randomised controlled trials: a systematic review. Trials2018; 19(1): 298.
12.
WeiskopfNGWengC. Methods and dimensions of electronic health record data quality assessment: enabling reuse for clinical research. J Am Med Inform Assoc2013; 20(1): 144–151.
13.
Ndounga DiakouLATrinquartLHrobjartssonA, et al. Comparison of central adjudication of outcomes and onsite outcome assessment on treatment effect estimates. Cochrane Database Syst Rev2016; 3: MR000043.
14.
KwakkenbosLJuszczakEHemkensLG, et al. Protocol for the development of a CONSORT extension for RCTs using cohorts and routinely collected health data. Res Integr Peer Rev2018; 3: 9.