US Department of Health Education and Welfare. The Belmont Report: ethical principles and guidelines for the protection of human subjects of research, http://www.hhs.gov/ohrp/humansubjects/guidance/belmont.html (1979, accessed 7 December 2014).
2.
LellouchJSchwartzD. L’essai therapéutique: éthique individuelle ou éthique collective?Rev Inst Int Stat1971; 39: 127–136.
3.
HeiligCMWeijerC. A critical history of individual and collective ethics in the lineage of Lellouch and Schwartz. Clin Trials2005; 2: 244–253.
4.
BerryDA. Editorial: adaptive clinical trials: the promise and the caution. J Clin Oncol2011; 29: 606–609.
5.
GaydosBKramsMPerevozskayaI. Adaptive dose-response studies. Drug Inf J2006; 40: 451–461.
6.
BerrySMSpinelliWLittmanGS. A Bayesian dose-finding trial with adaptive dose expansion to flexibly assess efficacy and safety of an investigational drug. Clin Trials2010; 7: 121–135.
7.
SkrivanekZBerrySBerryD. Application of adaptive design methodology in development of a long-acting glucagon-like peptide-1 analog (dulaglutide): statistical design and simulations. J Diabetes Sci Technol2012; 6: 1305–1318.
8.
BarkerADSigmanCCKelloffGJ. I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy. Clin Pharmacol Ther2009; 86: 97–100.
