Eosinophilia induced by interleukin-2 cancer immunotherapy may be associated with enhanced production of total IgE

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References

Atzpodien

, Kirchner

Cancer, cytokines and cytotoxic cells: interleukin-2 in the immunotherapy of human neoplasms.

Klin Wochenschr 1990; 68: 1–11.

Rosenberg

S.A.

, Lotze

M.T.

, Muul

L.M.

A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer and interleukin-2 or high-dose interleukin-2 alone.

N Engl J Med 1987; 316: 889–97.

MacDonald

, Gordon

A.A.

, Kajitani

Interleukin-2 treatment-associated eosinophilia is mediated by interleukin-5 production.

Br J Haematol 1990; 76: 168–73.

Devereux

, Linch

D.C.

Clinical significance of the haemopoietic growth factors.

Br J Cancer 1989; 61: 2–5.

Venge

What is the role of the eosinophil?

Thorax 1990; 45: 161–3.

Olsson

, Venge

The role of the eosinophil granulocyte in the inflammatory reaction.

Allergy 1979; 34: 353–7.

Reeder

W.H.

, Goodrich

B.E.

Pulmonary infiltration with eosinophilia (PIE syndrome).

Ann Int Med 1952; 36: 1217–21.