DRESS syndrome (Drug rash with eosinophilia and systemic symptoms) is a severe drug-induced hypersensitivity syndrome characterized by diffuse skin rash, fever, eosinophilia, atypical lymphocytes and organ involvement. We report a case of drug reaction with eosinophilia and systemic symptoms (DRESS) to sulphasalazine. A 54-year-old woman developed a widespread papulovesicular rash after treatment with sulphasalazine (1000 mg daily). She was successfully treated with systemic corticosteroids.
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