Oral focal mucinosis (OFM) is a rare mucosal lesion of unknown etiopathogenesis. It is considered the oral counterpart of cutaneous focal mucinosis. From the anatomo-pathological point of view it is characterised by a focal degeneration of myxoid type of connective tissue. A literature survey revealed 50 reports of OFM cases worldwide. Here, we present an even more rare case with tongue involvement. Particular emphasis is placed on diagnostic-differential aspects of this kind of lesion, both from the clinical and the histopathological point of view, in respect to other manifestations of tongue mucosa.
WilkMSchmoeckelC. Cutaneous focal mucinosis — A histopathological and immunohistochemical analysis of 11 cases. J Cutan Pathol1994; 21:446–52.
3.
SmithBCEllisGLMeis-KindblomJMWilliamsSB. Ectomesenchymal chondromyxoid tumor of the anterior tongue. Nineteen cases of new clinicopathologyc entity. Am J Surg Pathol1995; 19(5):519–30.
4.
LeeJAllenGMooreLGueS. Oral focal mucinosis in an adolescent: A casa report. Aust Dent J2012; 57(1):90–2.
5.
MadhusudhanASNagarajappaDManjunathaBSSwatiSaawarnBabuHS Charan. Oral focal mucinosis: Report of two cases. Rev Odonto Cienc2010; 25:310–3.
SistTCJrGreeneGWJr. Benign nerve sheath myxoma: Light and microscopic features of two cases. Oral Surg Oral Med Oral Patol1995; 47:441–4.
22.
MockliGCLjungBMGoldmanRL. Fine needle aspiration of intramuscular myxoma of the tongue. Acta Cytologica1993; 37:226–8.
23.
CarneyJAHruskaLSBeauichampGD. Dominant inheritance of the complex of myxomas, spotty pigmentation and endocrine overactivity. Mayo Clin1986; 61:165–172.
24.
GallagerRLHelwingEB. Neurothekeoma e benign cutaneous tumor of neural origin. Am J Clin Pathol1980; 74:759–64.
25.
HenzingerFMWeissSW. Soft tissue tumors. 4th ed.CV Mosby. St Louis, 2001.