Recent trials in neurology that should influence your practice

Pedley TA. Neurology at a crossroads: opportunities and challenges. JAMA 2014;311:1610-1.

Overview/introduction: Canadian best practice recommendations for stroke care. Available: www.strokebestpractices.ca/index.php/overview/introduction/ (accessed April 2, 2014).

The SPS3 Study Group. Blood-pressure targets in patients with recent lacunar stroke: the SPS3 randomized trial. Lancet 2013;382:507-15.

Wang Y Wang Y Zhao X . Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med 2013;369:11-9.

Steiner TJ. Headache in the world: public health and research priorities. Expert Rev Pharmacoecon Outcomes Res 2013;13:51-7.

Stovner L Hagen K Jensen R . The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia 2007;27:193-210.

Jackson JL Kuriyama A Hayashino Y. Botulinum toxin A for prophylactic treatment of migraine and tension headaches in adults: a meta-analysis. JAMA 2012;307:1736-45.

Multiple Sclerosis Society of Canada. About MS. Available: http://mssociety.ca/en/information/default.htm (accessed April 2, 2014).

Zamboni P Galeotti R Menegatti E . Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry 2009;80:392-9.

Zamboni P Galeotti R Menegatti E . A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency. J Vasc Surg 2009;50:1348-58.

Traboulsee AL Knox KB Machan L . Prevalence of extracranial venous narrowing on catheter venography in people with multiple sclerosis, their siblings, and unrelated healthy controls: a blinded, case-control study. Lancet 2014;383:138-45.

Alldredge BK Gelb AM Isaacs SM . A comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus. N Engl J Med 2001;345:631-7.

Silbergleit R Durkalski V Lowenstein D . Intramuscular versus intravenous therapy for prehospital status epilepticus. N Engl J Med 2012;366:591-600.

Moher D Liberati A Tetzlaff J Altman DG . PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009;6:e1000097.