An experimental study of a novel high-precision iliac vein pressure measuring device to evaluate iliac vein compression syndrome

Abstract

Objective

This study aims to assess the clinical value of a novel high-precision iliac vein pressure measuring device to diagnose and treat iliac vein compression syndrome.

Methods

A total of 38 patients with clinically confirmed iliac vein compression syndrome (all lesions on the left side) were selected. The iliac vein pressure and pressure recovery time (time taken for pressure to return to resting levels) were measured in four states: rest, affected limb elevation, ankle extension and flexion, and gastrocnemius muscle compression. Bilateral comparisons and pre- and post-treatment assessments were conducted.

Results

The left iliac vein pressure in the four states (42.40 ± 16.08 mmH₂O, 51.23 ± 17.63 mmH₂O, 70.26 ± 25.55 mmH₂O, and 111.47 ± 58.78 mmH₂O) and pressure recovery time (25.57 ± 10.65 s) were significantly higher compared to the right iliac vein pressure (30.67 ± 7.46 mmH₂O, 36.55 ± 8.59 mmH₂O, 44.84 ± 11.17 mmH₂O, and 52.96 ± 14.06 mmH₂O) and recovery time (18.92 ± 21.07 s) (p = .000). The pressure in patients with left iliac occlusion (179.07 ± 31.64 mmH₂O) was significantly higher than in patients with stenosis (79.91 ± 33.54 mmH₂O) (p = .000). In eight patients who underwent intraluminal iliac venous therapy, postoperative pressure (37.29 ± 7.53 mmH₂O, 44.74 ± 5.10 mmH₂O, 53.76 ± 5.36 mmH₂O, and 61.96 ± 7.27 mmH₂O) and pressure recovery time (20.88 ± 5.67 s) significantly improved compared to preoperative measurements (50.53 ± 8.21 mmH₂O, 60.03 ± 7.50 mmH₂O, 96.88 ± 11.67 mmH₂O, 177.11 ± 22.40 mmH₂O, and 35.50 ± 6.95 s) (p < .01). Despite improvements, postoperative left iliac pressure remained significantly higher than the right iliac pressure in different states (p < .05). The left iliac vein pressure increased significantly during ankle extension and flexion, as well as gastrocnemius muscle compression compared to resting and elevated limb states (p < .05).

Conclusion

The innovative high-precision iliac vein pressure measuring device enables rapid and accurate quantification of iliac vein pressure. As a functional diagnostic method, it holds considerable clinical value in diagnosing iliac vein compression syndrome and evaluating treatment efficacy.