Histologic findings after Guglielmi detachable coils endovascular embolisation have been studied in experimental aneurysms. Few reports describe histopathologic reactions to platinum coils in humans. In this report we describe gross, light microscopic pathology and scanning electron microscopy study of a ruptured basilar tip artery aneurysm in a patient who died 16 hours following coiling.
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References
1.
GuglielmiGViñuelaF: Electrothrombosis of saccular aneurysms via endovascular approach. Part 1: Electrochemical basis, technique and experimental results. J Neurosurg75: 1–7, 1991.
2.
GuglielmiGViñuelaF: Electrothrombosis of saccular aneurysms via endovascular approach. Part 2: Preliminary clinical experience. J Neurosurg75: 8–14, 1991.
3.
GravesVBPartingtonCR: Treatment of carotid aneurysms with platinum coils: An experimental study in dogs. Am J Neuroradiol11: 249–252, 1990.
4.
AhujaAHergenrotherR: Platinum coil coatings to increase thrombogenicity: A preliminary study in rabbits. Am J Neuroradiol14: 794–798, 1993.
5.
TenjinHFushikiS: Effect of Guglielmi detachable coils on experimental carotid artery aneurysms in primates. Stroke26: 2075–2080, 1995.
6.
MawadMMawadJ: Long-term histopathologic changes in canine aneurysms embolized with Guglielmi detachable coils. Am J Neuroradiol16: 7–13, 1995.
7.
ReulJSpetzgerU: The nature of early intraluminal thrombosis in terminal aneurysms occluded with Guglielmi detachable coils. Interventional Neuroradiology4: 39–48, 1998.
8.
MolyneuxAEllisonD: Histological findings in giant aneurysms treated with Guglielmi detachable coils. J Neurosurg83: 129–132, 1995.
9.
PorterPJStiverSI: Acute human histopathologic study of a saccular aneurysm treated by Guglielmi detachable coils. ASNR American Society of Neuroradiology. Toronto, Canada1997: 297.
10.
HorowitzMPurdyP: Scanning electron microscopic findings in a basilar tip aneurysm embolized with Guglielmi detachable coils. Am J Neuroradiol18: 688–690, 1997.
11.
ManabeHFujitaS: Embolisation of ruptured cerebral aneurysms with interlocking detachable coils in acute stage. Interventional Neuroradiology3: 49–63, 1997.
12.
MizoiKYoshimotoT: A pitfall in the surgery of a recurrent aneurysm after coil embolisation and its histological observation: Technical case report. Neurosurgery39: 165–168, 1996.
13.
ManabeHFujitaS: Rerupture of coil-embolised aneurysm during long-term observation. J Neurosurg88: 1096–1098, 1998.
14.
OzawaTKoikeT: Scanning electron microscopic study of the migrated platinum coil after endovascular embolisation of a giant cerebral aneurysm. Am J Neuroradiol19: 594–595, 1998.
15.
KoizumiTKawanoT: Histological findings in aneurysm treated with IDC: Scanning electron microscopical study. No Shinkei Geka25(11): 1027–31, 1997.
16.
GravesVBStrotherCM: Early treatment of ruptured aneurysms with Guglielmi detachable coils: Effect on subsequent bleeding. Neurosurgery37: 640–647, 1995.
17.
HorowitzMSamsonDPurdyP: Does electrothrombosis occur immediately after embolisation of an aneurysm with Guglielmi detachable coils?Am J Neuroradiol18: 510–513, 1997.