De Novo Appearance of Three Cavernomas in an Infant with Dural AV Shunts

Abstract

Cavernomas of the brain and spinal cord are malformations which are generally considered congenital and often found in young adults. Although the distinction of a sporadic and a hereditary type is discussed, the natural history is still poorly understood.

We present the unusual case of an infant first submitted to CT scan, MRI and MR-angiography at the age of three months, revealing multiple AV shunts of the superior sagittal and the sigmoid sinus, with a small pial supply. A second angiogram at the age of six months showed an additional parietal pial AVM. At this time, partial embolisation of the dural AV shunts was performed. At the age of three, the child was restudied by MRI and three formerly invisible cavernomas were detected.

Keywords

dural AV shunts cavernoma children

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References

Gallina

Nohra

: Multiple cavernoma of delayed appearance. Neurochirurgie 40: 322–325, 1994.

Gunel

Awad

: A founder mutation as a cause of cerebral cavernous malformation in Hispanic Americans. N Engl J Med 334: 946–951, 1996.

Horowitz

Kondziolka

: Multiple familial cavernous malformations evaluated over three generations with MR. Am J Neuroradiol 16: 1353–1355, 1995.

Kattapong

Hart

Davis

: Familial cerebral cavernous angiomas: Clinical and radiologic studies. Neurology 45(3 Pt1): 492–497, 1995.

Lasjaunias

: Revised Concept of the Congenital Nature of Vascular Malformations. In: Vascular diseases in neonates, infants and children. Springer Verlag 1997: 51–65.