Percutaneous Transluminal Angioplasty for Acute Thrombotic Occlusion of the Cervical Internal Carotid Artery Using a Perfusion Balloon Catheter

Abstract

We performed emergency percutaneous transluminal angioplasty (PTA) with a perfusion balloon catheter (PBC) for PTCA and, at the same time, thrombolytic therapy was administered by urokinase (UK) perfusion in five cases of severe cervical internal carotid artery stenosis in which sudden cerebral hemisphere ischemia occurred due to acute thrombotic obliteration.

In four out of the five cases, effective revascularization was obtained; three resulted in Good recovery, but one showed extensive cerebral infarction after PTA.

In the remaining one case, where stenosis of the internal carotid artery of the opposite side occurred subclinically, effective revascularization by PTA was impossible resulting in the death of this patient. While “artery to aetery embolism” was confirmed in all four cases in which revascularization was successful, most emboli were dissolved by combined thrombolysis.

As poor prognostic factors, findings of a low density area and closing of cerebral sulci in an initial CT and poor development of the collateral circulation mediating the circle of Willis and leptomeningeal collateral on the cerebral surface were indicated.

Since PBC is capable of performing PTA while assuring circulation distant from the balloon, it facilitates gradual and prolonged balloon inflation, which is said to be safer and more effective, and is considered a reasonable method of revascularization at the time of an acute obliteration in the cervical internal carotid artery. In addition, this method can be used as a bridge to carotid endarterectomy. However, “artery to artery embolism” accompanying PTA in the acute stage remains a major problem, and a combination of thrombolysis seems indispensable.