Haemorrhage is the most frequent revealing condition of brain arteriovenous malformations (bAVMs). We report a rare case of unruptured parietal bAVM revealed by spontaneous thrombosis of the main draining vein, responsible for a focal neurological deficit. The bAVM was embolized in emergency conditions; complete regression of the neurological symptoms was observed within five days after the embolization. Potential mechanisms of such spontaneous thrombosis of the bAVM’s main drainage pathway as well as an exhaustive review of the literature concerning this rare revealing condition are presented and discussed.
StapfCMastHSciaccaRR. The New York Islands AVM study: design, study progress, and initial results. Stroke2003; 34: e29–33.
2.
Forsting M (ed). Intracranial vascular malformations and aneurysms. Berlin/Heidelberg: Springer–Verlag, 2006.
3.
CrawfordPMWestCRChadwickDW. Arteriovenous malformations of the brain: natural history in unoperated patients. J Neurol Neurosurg Psychiatry1986; 49: 1–10.
4.
WilkinsRH. Natural history of intracranial vascular malformations: a review. Neurosurgery1985; 16: 421–430.
5.
FultsDKellyDLJr. Natural history of arteriovenous malformations of the brain: a clinical study. Neurosurgery1984; 15: 658–662.
6.
HofmeisterCStapfCHartmannA. Demographic, morphological, and clinical characteristics of 1289 patients with brain arteriovenous malformation. Stroke2000; 31: 1307–1310.
7.
The Arteriovenous Malformation Study Group. Arteriovenous malformations of the brain in adults. N Engl J Med1999; 340: 1812–1818.
8.
ChenYPawlikowskaLYaoJS. Interleukin-6 involvement in brain arteriovenous malformations. Ann Neurol2006; 59: 72–80.
9.
PancianiPPFontanellaMCarlinoC. Progressive spontaneous occlusion of a cerebellar AVM: pathogenetic hypothesis and review of literature. Clin Neurol Neurosurg2008; 110: 502–510.
10.
CronqvistMWirestamRRamgrenB. Endovascular treatment of intracerebral arteriovenous malformations: procedural safety, complications, and results evaluated by MR imaging, including diffusion and perfusion imaging. Am J Neuroradiol2006; 27: 162–176.
SawlaniVHandiqueAPhadkeRV. Spontaneous regression of cerebral AVM due to thrombosis of draining vein—angiographic and MRI demonstration. J Neurol Sci2004; 223: 195–198.
KuritaHShinMUekiK. Congestive brain oedema associated with a pial arteriovenous malformation with impaired venous drainage. Acta Neurochirurgica2001; 143: 339–342.
15.
PicardLDa CostaEAnxionnatR. Acute spontaneous hemorrhage after embolization of brain arteriovenous malformation with N-butyl cyanoacrylate. J Neuroradiol2001; 28: 147–65.
16.
HademenosGJMassoudTF. Risk of intracranial arteriovenous malformation rupture due to venous drainage impairment. A theoretical analysis. Stroke1996; 27: 1072–1083.
17.
YenCPKhaledMASchwyzerL. Early draining vein occlusion after gamma knife surgery for arteriovenous malformations. Neurosurgery2010; 67: 1293–1302.
