This paper reviews recent reports of the cholesterolaemic effects of palm oil. The evidence indicates that the substitution of palm oil or its lipid fractions for the usual fats in the diet does not result in an elevation of total serum cholesterol in lean, normocholesterolaemic individuals with a cholesterol intake of less than 300 mg per day. When threshold dietary levels of linoleic acid (18:2) are met, they tend to counter the cholesterol-raising effects of the 12- and 16-carbon saturated fatty acids. In view of this, the use of a cholesterol saturated-fat index to measure the hypercholesterolaemic and atherogenic potential of foods can be misleading, particularly when applied to palm oil. Nutritionists and health professionals need to keep abreast of recent knowledge on the cholesterolaemic impact of dietary fats and fatty acids.
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